Online citations, reference lists, and bibliographies.
← Back to Search

Potentially Inappropriate Medication Use In The Community-dwelling Elderly: Findings From The 1996 Medical Expenditure Panel Survey.

C. Zhan, J. Sangl, A. Bierman, M. R. Miller, B. Friedman, S. Wickizer, G. Meyer
Published 2001 · Medicine

Save to my Library
Download PDF
Analyze on Scholarcy Visualize in Litmaps
Share
Reduce the time it takes to create your bibliography by a factor of 10 by using the world’s favourite reference manager
Time to take this seriously.
Get Citationsy
CONTEXT Inappropriate medication use is a major patient safety concern, especially for the elderly population. Using explicit criteria, prior studies have found that 23.5% and 17.5% of the US community-dwelling elderly population used at least 1 of 20 potentially inappropriate medications in 1987 and 1992, respectively. OBJECTIVES To determine the prevalence of potentially inappropriate medication use in community-dwelling elderly persons in 1996, to assess trends over 10 years, categorize inappropriate medication use according to explicit criteria, and to examine risk factors for inappropriate medication use. DESIGN, SETTING, AND PARTICIPANTS Respondents aged 65 years or older (n = 2455) to the 1996 Medical Expenditure Panel Survey, a nationally representative survey of the US noninstitutionalized population were included. A 7-member expert panel was convened to categorize inappropriate medications. MAIN OUTCOME MEASURE Prevalence of use of 33 potentially inappropriate medications. RESULTS In 1996, 21.3% (95% confidence interval [CI], 19.5%-23.1%) of community-dwelling elderly patients in the United States received at least 1 of 33 potentially inappropriate medications. Using the expert panel's classifications, about 2.6% of elderly patients (95% CI, 2.0%-3.2%) used at least 1 of the 11 medications that should always be avoided by elderly patients; 9.1% (95% CI, 7.9%-10.3%) used at least 1 of the 8 that would rarely be appropriate; and 13.3% (95% CI, 11.7%-14.9%) used at least 1 of the 14 medications that have some indications but are often misused. Use of some inappropriate medications declined between 1987 and 1996. Persons with poor health and more prescriptions had a significantly higher risk of inappropriate medication use. CONCLUSIONS Overall inappropriate medication use in elderly patients remains a serious problem. Despite challenges in using explicit criteria for assessing inappropriate medications for elderly patients, such criteria can be applied to population-based surveys to identify opportunities to improve quality of care and patient safety. Enhancements of existing data sources to include dosage, duration, and indication may augment national improvement and monitoring efforts.
This paper references
ensuring safety before funding
Newcomer L. Medicare pharmacy coverage (1952)
10.2105/AJPH.70.5.485
A study of antipsychotic drug use in nursing homes: epidemiologic evidence suggesting misuse.
W. Ray (1980)
10.1016/S0140-6736(84)90775-X
PRESCRIPTION OF CONTRAINDICATED AND INTERACTING DRUGS IN ELDERLY PATIENTS ADMITTED TO HOSPITAL
M. Gosney (1984)
10.1001/ARCHINTE.1991.00400090107019
Explicit criteria for determining inappropriate medication use in nursing home residents. UCLA Division of Geriatric Medicine.
M. Beers (1991)
10.1001/ARCHINTE.151.9.1825
Explicit criteria for determining inappropriate medication use in nursing home residents. UCLA Division of Geriatric Medicine.
M. Beers (1991)
10.7326/0003-4819-117-8-684
Inappropriate medication prescribing in skilled-nursing facilities.
M. Beers (1992)
10.1093/AGEING/21.4.294
Inappropriate medication is a major cause of adverse drug reactions in elderly patients.
C. Lindley (1992)
10.1001/ARCHINTE.1993.00410060015003
Reserpine and the medical marketplace.
F. Lederle (1993)
10.1001/JAMA.1994.03520040054040
Inappropriate drug prescribing for the community-dwelling elderly.
S. Willcox (1994)
10.1001/JAMA.1994.03520040078046
Suboptimal medication use in the elderly. The tip of the iceberg.
J. Gurwitz (1994)
10.1111/j.1532-5415.1995.tb06098.x
Inappropriate Use of Nonpsychotropic Medications in Nursing Homes
B. Williams (1995)
10.1111/j.2042-7174.1996.tb00844.x
The Delphi and nominal group techniques in health services research
J. Cantrill (1996)
10.2105/AJPH.87.3.404
Inappropriate drug prescriptions for elderly residents of board and care facilities.
D. Spore (1997)
10.1001/ARCHINTE.1997.00440350031003
Explicit criteria for determining potentially inappropriate medication use by the elderly. An update.
M. Beers (1997)
10.1046/J.1365-2753.1997.T01-1-00005.X
Auditing prescription practice using explicit criteria and computerized drug benefit claims data.
G. Anderson (1997)
10.1177/106002809703100702
Inappropriate Medication Prescribing for the Elderly by Office-Based Physicians
R. Aparasu (1997)
Defining inappropriate practices in prescribing for elderly people: a national consensus panel.
P. McLeod (1997)
Nonresponse adjustment strategy in the 1996 Medical Expenditure Panel Survey: Household component
S. Cohen (1998)
10.1001/JAMA.280.14.1249
Improving prescribing patterns for the elderly through an online drug utilization review intervention: a system linking the physician, pharmacist, and computer.
M. Monane (1998)
10.1093/AJHP/56.5.433
Inappropriate prescribing for elderly outpatients.
R. Aparasu (1999)
10.1111/j.1532-5415.1999.tb01289.x
Inappropriate Medication Prescribing in Homebound Older Adults
A. Golden (1999)
10.1001/ARCHINTE.160.18.2825
Prescribing potentially inappropriate psychotropic medications to the ambulatory elderly.
J. Mort (2000)
10.1111/j.1532-5415.2000.tb04782.x
Sedative, Hypnotic, and Antianxiety Medication Use in an Aging Cohort over Ten Years: A Racial Comparison
D. Blazer (2000)
Why the Elderly Need Individualized Pharmaceutical Care
D. Nash (2000)
10.1001/ARCHINTE.160.18.2717
Preventable medical injuries in older patients.
J. Rothschild (2000)
10.1177/009127000004001001
American College of Clinical Pharmacology Response to the Institute of Medicine Report “To Err Is Human: Building a Safer Health System”
L. T. Kohn (2000)
Medicare pharmacy coverage: ensuring safety before funding.
L. Newcomer (2000)
10.1046/j.1532-5415.2001.49042.x
Suboptimal Prescribing in Older Inpatients and Outpatients
J. Hanlon (2001)
10.7326/0003-4819-134-9_PART_1-200105010-00029
Geriatrics Review Syllabus: A Core Curriculum in Geriatric Medicine
Rocco Vivenzio (2001)
A study of an POTENTIALLY INAPPROPRIATE PRESCRIBING FOR THE ELDERLY 2828 JAMA, December 12, 2001—Vol
W Ray (2001)
A study of an POTENTIALLY INAPPROPRIATE PRESCRIBING FOR THE ELDERLY
W Ray (2001)
Outpatient Prescription Drugs: Data Collection and Editing in the 1996 Medical Expenditure Panel Survey (HC010A)
JF Moeller (2001)
10.7326/0003-4819-112-8-636_2
Geriatrics Review Syllabus: A Core Curriculum in Geriatric Medicine
E. Cobb (2002)



This paper is referenced by
10.1186/s12877-021-02246-2
An examination of three prescribing cascades in a cohort of older adults with dementia
Shanna C. Trenaman (2021)
10.1186/s13012-020-01078-9
Rationale and design of the Novel Uses of adaptive Designs to Guide provider Engagement in Electronic Health Records (NUDGE-EHR) pragmatic adaptive randomized trial: a trial protocol
J. Lauffenburger (2021)
10.18203/2319-2003.IJBCP20210559
A prospective study on prescribing pattern of drugs in geriatric patients in the department of medicine in a tertiary care center
Priya Mohan B. N. (2021)
10.1016/S2666-7568(21)00054-4
Polypharmacy, inappropriate prescribing, and deprescribing in older people: through a sex and gender lens
P. Rochon (2021)
10.1186/s12877-021-02024-0
Development of an explicit tool assessing potentially inappropriate medication use in Hong Kong elder patients
Huanyu Zhang (2021)
10.2147/CIA.S309063
High-Risk Perioperative Medications in the Chinese Elderly Population
Shuying Wang (2021)
10.1007/s00432-020-03252-4
Polypharmacy as a prognostic factor in older patients with advanced non-small-cell lung cancer treated with anti-PD-1/PD-L1 antibody-based immunotherapy
T. Hakozaki (2020)
10.1016/j.cct.2020.106069
A randomized clinical trial of a collaborative home-based diabetes intervention to reduce emergency department visits and hospitalizations in black individuals with diabetes.
R. Casten (2020)
Kalkulierte parenterale Initialtherapie bakterieller Infektionen: Antibiotika-Therapie beim alten Menschen
Leitlinie „Kalkulierte (2020)
10.3390/medicina56070320
Pharmacological Interactions in the Elderly
E. Błeszyńska (2020)
10.1093/gerona/glaa128
Systematic Review and Meta-Analysis on the Associations of Polypharmacy and Potentially Inappropriate Medication with Adverse Outcomes in Older Cancer Patients.
Li-Ju Chen (2020)
Le bilan partagé de médication : un nouvel outil dans la prise en charge du patient âgé et polymédiqué à l'officine
Angélique Beillier (2020)
10.4018/978-1-7998-3066-5.ch007
Geriatric Interprofessional Education
Tina Meyer (2020)
10.3390/ijerph16122189
Association between Potentially Inappropriate Medication Use and Chronic Diseases in the Elderly
Tzu-Chueh Wang (2019)
10.1093/ageing/afz092
A qualitative exploration of the experiences of community dwelling older adults with sensory impairment/s receiving polypharmacy on their pharmaceutical care journey
A. Smith (2019)
10.1371/journal.pone.0217406
Identifying potential prescribing safety indicators related to mental health disorders and medications: A systematic review
W. Khawagi (2019)
10.1111/bcpt.13096
Patient‐ and health care‐related factors associated with initiation of potentially inappropriate medication in community‐dwelling older persons
Virva Hyttinen (2019)
10.1136/bmjopen-2018-027290
Quality of prescribing in older people from a broad family physician perspective: a descriptive pilot study
N. Parodi López (2019)
10.3389/fphar.2019.00592
Physician’s Knowledge of Appropriate Prescribing for the Elderly—A Survey Among Family and Internal Medicine Physicians in Nigeria
J. Fadare (2019)
10.1634/theoncologist.2019-0406
Associations of Polypharmacy and Inappropriate Medications with Adverse Outcomes in Older Adults with Cancer: A Systematic Review and Meta-Analysis.
Mostafa R Mohamed (2019)
10.1111/jcpt.12811
Potentially inappropriate medications with risk of cardiovascular adverse events in the elderly: A systematic review of tools addressing inappropriate prescribing
J. Aguiar (2019)
10.1186/s12877-019-1287-8
Prevalence of Potentially Inappropriate Medication use in older drivers
Guohua Li (2019)
10.1186/s12889-019-8069-2
MOBIlity assessment with modern TEChnology in older patients’ real-life by the General Practitioner: the MOBITEC-GP study protocol
Mareike Münch (2019)
Médicaments potentiellement inappropriés chez les personnes âgées : mise à jour d'une liste adaptée à la thérapeutique en médecine générale
D. Coulibaly (2019)
10.1634/theoncologist.2018-0807
Polypharmacy in Patients with Ovarian Cancer.
Sean Oldak (2019)
10.1016/J.REFIRI.2017.12.001
La déprescription chez les aînés et le rôle des infirmières pour tendre vers des polymédications appropriées, une revue narrative de la littérature
Caroline Sirois (2018)
10.1007/s00228-018-2446-0
Potentially inappropriate medication in the elderly: a systematic review of validated explicit criteria
F. R. Motter (2018)
10.1016/j.jgo.2017.07.015
Polypharmacy, potentially inappropriate medications and drug-drug interactions in geriatric patients with hematologic malignancy: Observational single-center study of 122 patients.
D. Léger (2018)
10.1007/s00228-018-2603-5
Medication use in older patients and age-blind approach: narrative literature review (insufficient evidence on the efficacy and safety of drugs in older age, frequent use of PIMs and polypharmacy, and underuse of highly beneficial nonpharmacological strategies)
D. Fialová (2018)
10.2147/TCRM.S170475
Polypharmacy leads to increased prevalence of potentially inappropriate medication in the Indonesian geriatric population visiting primary care facilities
R. Abdulah (2018)
10.1002/phar.2095
Quality of Prescribing by Physicians, Nurse Practitioners, and Physician Assistants in the United States
Shiyin Jiao (2018)
10.1007/978-3-319-73820-8_14
Ageism in Medication Use in Older Patients
D. Fialová (2018)
See more
Semantic Scholar Logo Some data provided by SemanticScholar