Online citations, reference lists, and bibliographies.

Closure Of Mucosal Defects Over Exposed Mandibular Plates Using Fibrin Glue.

H P Gaboriau, Peter C Belafsky, Nima Pahlavan, Ronald G. Amedee
Published 1999 · Medicine
Cite This
Download PDF
Analyze on Scholarcy
Share
BACKGROUND Mandibular plates may become exposed following radiation therapy, infection, and mucosal necrosis. This may lead to early removal of the mandibular plates with subsequent instability of bone fragments. OBJECTIVE To compare fibrin glue, a bioadhesive, with traditional sutures in closing mucosa over exposed mandibular plates in a cat. DESIGN Prospective matched-pairs analysis. SUBJECTS Nine cats were used, and each cat served as its own control. INTERVENTION Bilateral mandibular plates were fixed on the buccal side of the mandible of 9 cats. The surgical defects over the plates were left uncovered. After 4 days, the plates on the right side were covered with a mucosal graft fastened with fibrin glue, and on the left side the grafts were secured with sutures. After 10 days, the grafts were excised and a histological examination was performed. RESULTS The mean operative time for coverage was 2 minutes 11 seconds for the fibrin glue and 12 minutes 48 seconds for the sutures (P < .001). Gross examination revealed granulation or ulceration in 3 of the fibrin and 9 of the suture specimens (P < .005). All specimens displayed mild-to-moderate acute and chronic inflammation. All sutured specimens showed focal foreign body-type giant cells surrounding fragments of bone and suture. Two mandibular plates were partially exposed on the fibrin glue side. CONCLUSIONS The use of fibrin glue to cover exposed mandibular plates is safe and well tolerated in cats. Glue application requires a shorter operative time and is associated with fewer occurrences of granulation and ulceration when compared with suture fixation. Further studies are indicated to titrate the concentration of fibrin glue and to prevent plate exposure.
This paper references
Fibrinsutureofperipheral nerves
MK Wax (1940)
10.1016/0142-9612(95)93113-R
Preparation and use of fibrin glue in surgery.
Frederick H Silver (1995)
Dtsch Med Wochenschr
S Bergel (1909)
Quotable Don't forget that Pare centuries ago wrote We dress them, God heals them
(1999)
10.1016/0278-2391(85)90129-6
Fibrin seal: the state of the art.
Helene Matras (1985)
Use of fibrin glue in maxillofacial surgery.
Bradley R. Davis (1998)
Prosthetic plate mandibular reconstruction.
Davidson Mj (1991)
10.1097/00006534-199703000-00035
The Use of Fibrin Sealant in the Prevention of Seromas
Renato Saltz (1997)
Fibrinsutureofperipheral nerves
MK Wax (1940)
10.1016/0007-1226(94)90087-6
Face lifts and sprayed fibrin glue: an outcome analysis of 200 patients.
Daniel Alexandre Marchac (1994)
Fibrin suture of peripheral nerves Contemporary management of cerebrospinal fluid rhinorrhea
Jz Young (1940)
10.1007/978-3-642-58789-4
Manual of Internal Fixation in the Cranio-Facial Skeleton
Leon A. Assael Dmd (1998)
10.1097/00006534-199709000-00027
Fibrin glue fixation in forehead endoscopy: evaluation of our experience with 206 cases.
Daniel Alexandre Marchac (1997)
Complications associated with rigid fixation of mandibulotomies.
Karen Jee-Hae McCann (1994)
Fibrin glue in facial plastic and reconstructive surgery.
David Archer Ellis (1988)
10.1097/00006534-199505000-00010
The free flap and plate in oromandibular reconstruction: long-term review and indications.
J. Brian Boyd (1995)
10.1055/s-0029-1201395
Ueber Wirkungen des Fibrins
S. Bergel (1909)
10.1016/S0039-6109(05)70573-9
The role of sutures and fibrin sealant in wound healing.
William D. Spotnitz (1997)
10.1001/archotol.1995.01890010056010
Rigid fixation of vascularized bone grafts in mandibular reconstruction.
Neal Futran (1995)
10.1097/00005537-199606000-00022
Use of fibrin glue in parotidectomy closure.
Joël Depondt (1996)
10.1001/archotol.124.6.665
Sutureless cartilage graft laryngotracheal reconstruction using fibrin sealant.
Dongwoo Kang (1998)
10.1016/S0194-59989770292-4
Contemporary Management of Cerebrospinal Fluid Rhinorrhea
Mark Wax (1997)
10.1016/0002-9610(89)90009-3
Mandibular reconstruction using AO plates.
Douglas W. Klotch (1987)
10.1097/00006534-199112000-00009
Experimental and clinical applications of fibrin glue.
Renato Saltz (1991)



This paper is referenced by
Semantic Scholar Logo Some data provided by SemanticScholar