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Association Between Hidradenitis Suppurativa And Lymphoma

Rachel Tannenbaum, Andrew Strunk, Amit Garg
Published 2019 · Medicine
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Methods | This cross-sectional cohort analysis used standardized electronic health record information of the IBM Explorys database for 55 million patients from 27 integrated health systems across the United States.1 The analysis was limited to adults aged at least 18 years with active status between July 16, 2013, and July 16, 2018, who had complete information on sex and age. The Systemized Nomenclature of Medicine–Clinical Terms hidradenitis, non-Hodgkin’s lymphoma, Hodgkin’s disease, and primary cutaneous T-cell lymphoma were used to identify cohorts.2 Use of electronic health data to identify lymphoma cohorts has been performed in prior studies evaluating associations between lymphoma and other conditions, including psoriasis.3,4 We assessed overall lymphoma prevalences among patients with and without HS, and within demographic subgroups. Prevalences were compared using a logistic regression model controlling for age and sex. All hypothesis tests were 2-tailed and conducted at the .05 significance level. This study was approved by the human subjects committee at the Feinstein Institute for Medical Research at Northwell Health, which waived the need for informed consent for deidentified data.
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