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Changes In Sexual Functioning And Sex Hormone Levels In Women Following Bariatric Surgery.

David B Sarwer, Jacqueline C. Spitzer, Thomas A Wadden, James E Mitchell, Kathryn L Lancaster, Anita P Courcoulas, William F Gourash, Raymond C. Rosen, Nicholas J. Christian
Published 2014 · Medicine
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IMPORTANCE Obesity has been associated with impairments in sexual function and untoward changes in reproductive hormones in women. Relatively few studies have investigated changes in these domains following bariatric surgery. OBJECTIVE To investigate changes in sexual functioning, sex hormone levels, and relevant psychosocial constructs in women who underwent bariatric surgery. DESIGN, SETTING, AND PARTICIPANTS A prospective cohort study of 106 women from phase 2 of the Longitudinal Assessment of Bariatric Surgery who underwent bariatric surgery (median [interquartile range] body mass index, 44.5 [41.4-49.7]). Assessments were completed between 2006 and 2012. INTERVENTIONS Bariatric surgery was performed by a surgeon certified by the Longitudinal Assessment of Bariatric Surgery (85 women underwent a Roux-en-Y gastric bypass, and 21 women underwent laparoscopic adjustable gastric banding). MAIN OUTCOMES AND MEASURES Sexual functioning was assessed by use of the Female Sexual Function Index. Hormones were assessed by use of a blood assay. Quality of life, body image, depressive symptoms, and marital adjustment were assessed by use of validated questionnaires. RESULTS Women lost a mean 32.7% (95% CI, 30.7%-34.7%) of initial body weight at postoperative year 1 and a mean 33.5% (95% CI, 31.5%-35.6%) at postoperative year 2. Two years following surgery, women reported significant improvements in overall sexual functioning and specific domains of sexual functioning: arousal, lubrication, desires, and satisfaction. They also experienced significant changes at 2 years in all hormones of interest. Women reported significant improvements in most domains of quality of life, as well as body image and depressive symptoms, within the first year after surgery, with these improvements being maintained through the second postoperative year. CONCLUSIONS AND RELEVANCE Women who underwent bariatric surgery had significant improvements in overall sexual functioning, in most reproductive hormones of interest, and in psychosocial status. Improvements in sexual health can be added to the list of health benefits associated with bariatric surgery. TRIAL REGISTRATION Identifier: NCT00670098.
This paper references
Manual for the Impact of Weight on Quality of Life Measure (IWQOL and IWQOL-Lite)
RL Kolotkin (2011)
Development of a brief measure to assess quality of life in obesity.
Ronette L Kolotkin (2001)
Health-Related Quality of Life and Symptoms of Depression in Extremely Obese Persons Seeking Bariatric Surgery
Anthony N. Fabricatore (2005)
Comparison of psychosocial status in treatment-seeking women with class III vs. class I-II obesity.
Thomas A Wadden (2006)
Changes in quality of life and body image after gastric bypass surgery.
David B Sarwer (2010)
Changes in depression and quality of life in obese individuals with binge eating disorder: bariatric surgery versus lifestyle modification.
Lucy F Faulconbridge (2013)
Baseline characteristics of participants in the Longitudinal Assessment of Bariatric Surgery-2 (LABS-2) study.
Steven H. Belle (2013)
Relationship between Sexual Function and Quality of Life in Obese Persons Seeking Weight Reduction
Reneé H Moore (2013)
Health outcomes of gastric bypass patients compared to nonsurgical, nonintervened severely obese.
Ted D. Adams (2010)
Assessing Impact of Weight on Quality of Life.
Ronette L Kolotkin (1995)
A Review of the Relationships Between Extreme Obesity, Quality of Life, and Sexual Function
David B Sarwer (2012)
SF-36 health survey: Manual and interpretation guide
John E Ware (2003)
Effects of gastric bypass surgery on female reproductive function.
Richard S Legro (2012)
Quality of life and psychosocial adjustment in patients after Roux-en-Y gastric bypass: a brief report.
Maureen P. Dymek (2001)
Quality-of-Life Assessment of Morbidly Obese Patients who have Undergone a Lap-Band® Operation: 2-Year Follow-Up Study: Is the MOS SF-36 a useful instrument to measure quality of life in morbidly obese patients?
Rogier Hörchner (2001)
Characteristics of morbidly obese patients before gastric bypass surgery.
Martina de Zwaan (2003)
Pre-operative Predictors of Weight Loss at 1-Year after Lap-Band® Surgery
J. Bryan Dixon (2001)
Response to Comment on: Wing et al. Effect of Intensive Lifestyle Intervention on Sexual Dysfunction in Women With Type 2 Diabetes: Results From an Ancillary Look AHEAD Study. Diabetes Care 2013;36:2937–2944
Rena R Wing (2013)
Safety and efficacy of bariatric surgery: Longitudinal Assessment of Bariatric Surgery.
Steven H. Belle (2007)
The development and validation of the body shape questionnaire
Peter J. Cooper (1987)
Psychosocial and behavioral aspects of bariatric surgery.
David B Sarwer (2005)
The impact of obesity on hormonal parameters in hirsute and nonhirsute women.
Donatella Bernasconi (1996)
Effect of Intensive Lifestyle Intervention on Sexual Dysfunction in Women With Type 2 Diabetes
Rena R Wing (2013)
Two-year changes in health-related quality of life in gastric bypass patients compared with severely obese controls.
Ronette L Kolotkin (2009)
An inventory for measuring depression.
A. T. Beck (1961)
Psychopathology before surgery in the longitudinal assessment of bariatric surgery-3 (LABS-3) psychosocial study.
James E Mitchell (2012)
Perioperative safety in the longitudinal assessment of bariatric surgery.
David R. Flum (2009)
Prevalence and degree of sexual dysfunction in a sample of women seeking bariatric surgery.
Dale S Bond (2009)
Quality of life after RouxenY gastric bypass and changes in bodymass index and obesityrelated comorbidities
C Julia (2012)
Sexual functioning and sex hormones in persons with extreme obesity and seeking surgical and nonsurgical weight loss.
David B Sarwer (2013)
The Female Sexual Function Index (FSFI): Cross-Validation and Development of Clinical Cutoff Scores
Markus Wiegel (2005)
Quality of life after Roux-en-Y gastric bypass and changes in body mass index and obesity-related comorbidities.
Carla Júlia (2013)
Sex difference in the effect of obesity on 24-hour mean serum gonadotropin levels.
Gladys Witt Strain (2003)
Baseline characteristics of participants in the Longitudinal Assessment of Bariatric Surgery2 ( LABS2 ) study [ published online March 7 ,
SH Belle (2013)
Obesity and the role of gut and adipose hormones in female reproduction.
Gabriella G. Gosman (2006)
The impact of a primary care-based weight loss intervention on the quality of life
David B Sarwer (2013)
Body mass index, circulating levels of sex-steroid hormones, IGF-I and IGF-binding protein-3: a cross-sectional study in healthy women.
Annekatrin Lukanova (2004)
Swedish obese subjects (SOS) – an intervention study of obesity. Two-year follow-up of health-related quality of life (HRQL) and eating behavior after gastric surgery for severe obesity
Johnny Karlsson (1998)
Sf-36r Health Survey Manual And Interpretation Guide
Kristin K. Snow (2015)
Obesity and sexual quality of life.
Ronette L Kolotkin (2006)
Obesity and infertility
Renato Pasquali (2007)
Significant resolution of female sexual dysfunction after bariatric surgery.
Dale S Bond (2011)
Interrelationships between weight loss, body fat distribution and sex hormones in pre- and postmenopausal obese women.
E. Turcato (1997)
The Female Sexual Function Index (FSFI): a multidimensional self-report instrument for the assessment of female sexual function.
Raymond C. Rosen (2000)
Measuring Dyadic Adjustment: New Scales for Assessing the Quality of Marriage and Similar Dyads.
Graham B. Spanier (1976)
Sex Hormone Changes in Morbidly Obese Patients after Vertical Banded Gastroplasty
Elias A. Bastounis (1998)
The impact of body image experiences: development of the body image quality of life inventory.
Thomas F. Cash (2002)
Quality of Life and Psychosocial Adjustment in Patients after Roux-en-Y Gastric Report Bypass: A Brief Report
Maureen P. Dymek (2001)
Health-Related Quality of Life in Patients Seeking Gastric Bypass Surgery vs Non-Treatment-Seeking Controls
Ronette L Kolotkin (2003)
Visceral fat accumulation in relation to sex hormones in obese men and women undergoing weight loss therapy.
Rianne Leenen (1994)
Sexual dysfunction is common in the morbidly obese male and improves after gastric bypass surgery.
Ramsey M. Dallal (2008)
Six-year changes in health-related quality of life in gastric bypass patients versus obese comparison groups.
Ronette L Kolotkin (2012)

This paper is referenced by
New insights on bariatric surgery outcomes.
Sayeed Ikramuddin (2013)
Sexual Activity After Bariatric Surgery: A Prospective Monocentric Study Using the PISQ-IR Questionnaire.
Patrick-Julien Treacy (2019)
Gastric Bypass Surgery but not Caloric Restriction Improves Reproductive Function in Obese Mice
Aaron P. Frank (2015)
Issues Surrounding the Relationship Between Sexual Function and Bariatric Surgery
Derek Larkin (2017)
Sexual functioning of men and women with severe obesity before bariatric surgery.
Kristine J. Steffen (2017)
Effect of Body Weight on Sexual Function in Men and Women
Jenna Bates (2019)
The Effect of Bariatric Surgery on Patient HRQOL and Sexual Health During a 1-Year Postoperative Period
Vasileios Efthymiou (2014)
Romantic, sexual, and sexual risk behaviours of adolescent females with severe obesity
Jennifer N. Becnel (2017)
Sexual Dysfunctions in Obese Women Before and After Bariatric Surgery
Dita Pichlerová (2019)
From Table to Bedroom: Nutritional Status, Dietary Interventions, and Women’s Sexual Function
Sean M. McNabney (2019)
Beyond 'truly exceptional': A tribute to Thomas F. Cash, an innovative leader in the body image field.
Tracy L Tylka (2019)
Diet and Female Sexual Health.
Maxwell Towe (2019)
Bariatric surgery repercussions on the quality of life , biochemical profile , and blood pressure of patients with morbid obesity
Lucas Silva Franco de Oliveira ()
Body mass index and health‐related quality of life
R Apple (2018)
Commentary on “Critical Flaws in the FSFI and IIEF”
Raymond C. Rosen (2014)
Bariatric Surgery Significantly Improves the Quality of Sexual Life and Self-esteem in Morbidly Obese Women
Faredj Cherick (2019)
Evaluación de la función sexual en pacientes con obesidad, antes y después de la cirugía bariátrica
José Miguel Silva (2019)
Changes in Dietary Intake and Eating Behavior in Adolescents After Bariatric Surgery: an Ancillary Study to the Teen-LABS Consortium
David B Sarwer (2017)
Associations between relationship stability, relationship quality, and weight loss outcomes among bariatric surgery patients.
Shannon M. Clark (2014)
Sexual Dysfunction in Eating Disorders
Giovanni Castellini (2018)
Improvements of health-related quality of life 5 years after gastric bypass. What is important besides weight loss? A study from Scandinavian Obesity Surgery Register.
Mustafa Raoof (2020)
Sexual health and wellbeing
Geoffrey Hackett (2017)
Impacto da cirurgia bariátrica na imagem corporal e saúde mental
Lília Gisela Simões Cipriano (2019)
Obesity and Sexual Dysfunction: Making the Connection.
Anne Katz (2017)
Sexuality in eating disorders patients: etiological factors, sexual dysfunction and identity issues. A systematic review
Giovanni Castellini (2016)
Effects of obesity treatment on female reproduction: results do not match expectations.
Richard S Legro (2017)
Concomitant Early Abdominoplasty and Sleeve Gastrectomy can destroy the Triangle of Danger of Obesity , Bad Quality of Life and Depression in Obese Patients
Hussein Elgohary (2016)
Effect of Bariatric Surgery on Sexual Function and Sex Hormone Levels in Obese Patients: A Meta-Analysis
Junping Wen (2018)
4-Year Changes in Sex Hormones, Sexual Functioning, and Psychosocial Status in Women Who Underwent Bariatric Surgery
David B Sarwer (2017)
Suicide, Self-harm, and Depression After Gastric Bypass Surgery: A Nationwide Cohort Study
Ylva Trolle Lagerros (2017)
Obesity and Sexual Functioning
David B Sarwer (2018)
Risk factors for sexual dysfunction in BRCA mutation carriers after risk-reducing salpingo-oophorectomy
Jessica L Chan (2019)
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