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A Novel Electrogenerated Chemiluminescence Reaction Scheme Using Core‐Shell Luminol‐Based SiO2 Nanoparticles As A Regulator And Its Analytical Application

L. Zhang, Xingwang Zheng, Z. Guo
Published 2007 · Chemistry

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A novel core-shell luminol-based SiO2 nanoparticle was synthesized by two step micro-emulsion method. While these nanoparticles were used as electrogenerated chemiluminescence (ECL) reagent, the electrochemical (EC) reaction as well as the subsequent chemiluminescence (CL) reaction not only could be separated spatially, but also presented high efficiency for analytical purpose. In this case, the core-shell luminol-based SiO2 nanoparticles offered more potential to avoid the contradiction between the EC and the CL reaction conditions. A new ECL method based on the nanoparticle was developed, and isoniazid was selected as a model analyte to illustrate the characteristics of this new ECL method. Under the selected conditions, the proposed ECL response to isoniazid concentration was linear in the range of 1.0×10−10 to 1.0×10−6 g/mL with 2×10−11 g/mL detection limit.
This paper references
Optical nanosensors for chemical analysis inside single living cells. 2. Sensors for pH and calcium and the intracellular application of PEBBLE sensors.
H. Clark (1999)
Biochemically functionalized silica nanoparticles.
M. Qhobosheane (2001)
Occurrence, mechanisms and analytical applications of electrogenerated chemiluminescence. A review
A. W. Knight (1994)
Flow-injection electrogenerated chemiluminescence determination of isoniazid using luminol.
X. Zheng (2001)
Electrochemiluminescence of hydrogen peroxide-luminol at a carbon electrode
S. Sakura (1992)
Flow injection analysis of pyrogallol with enhanced electrochemiluminescent detection
Y. Sun (2000)
Flow-injection electrogenerated chemiluminescence detection of hydrazine based on its in-situ electrochemical modification at a pre-anodized platinum electrode.
Xingwang Zheng (2002)
A review of recent trends in analytical applications of electrogenerated chemiluminescence
A. W. Knight (1999)
Optical nanosensors for chemical analysis inside single living cells. 1. Fabrication, characterization, and methods for intracellular delivery of PEBBLE sensors.
H. Clark (1999)
A real-time ratiometric method for the determination of molecular oxygen inside living cells using sol-gel-based spherical optical nanosensors with applications to rat C6 glioma.
H. Xu (2001)
Determination of lipid hydroperoxides by electrochemiluminescence
S. Sakura (1992)
Multichannel electrochemiluminescence of luminol in neutral and alkaline aqueous solutions on a gold nanoparticle self-assembled electrode.
Hua Cui (2004)
Conjugation of biomolecules with luminophore-doped silica nanoparticles for photostable biomarkers.
S. Santra (2001)

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