Online citations, reference lists, and bibliographies.
← Back to Search

Projection Of Jaw‐muscle Spindle Afferents To The Caudal Brainstem In Rats Demonstrated Using Intracellular Biotinamide

P. Luo, R. Wong, D. Dessem
Published 1995 · Biology, Medicine

Save to my Library
Download PDF
Analyze on Scholarcy
Share
Intracellular staining with biotinamide was used to study the axonal projection and synaptic morphology of rat jaw‐muscle spindle afferents. Intracellular recordings in the mesencephalic trigeminal nucleus (Vme) were identified as spindle afferent responses by their increased firing during stretching of the jaw‐elevator muscles. Biotinamide‐stained axon collaterals with boutons were found in the trigeminal motor nucleus (Vmo), Vme, the region dorsal to Vmo including the supratrigeminal region, the dorsomedial portion of the trigeminal principal sensory nucleus, and the dorsomedial part of the rostral spinal trigeminal subnucleus oralis. Additional, previously undescribed projections of jaw‐muscle spindle afferents were found to the dorsomedial portiori of the caudal spinal trigeminal subnucleus oralis (Vodm), the dorsomedial part of the spinal trigeminal subnucleus interpolaris (Vidm), the caudal parvicellular reticular formation, laminae IV and V of the spinal trigeminal subnucleus caudalis (Vc), and the dorsal division of the medullary reticular field. Labeled spindle boutons in Vodm formed predominately axodendritic synapses. Some of these boutons received presynaptic inputs from unlabeled P‐type boutons containing clear, spherical, or flattened vesicles. In Vidm, labeled collaterals and boutons were densely clustered into glomerular‐like structures. Labeled boutons in Vidm made axodendritic, axosomatic, and axoaxonic synapses and received synaptic contacts from unlabeled boutons containng clear, spherical, or flat and pleomorphic vesicles. Unlabeled presynaptic boutons in Vidrn occasionally contained dense core vesicles. Labeled boutons in Vc mainly formed synaptic contacts with large diameter dendrites. This projection of jaw‐muscle spindle afferents to caudal brainstem regions may play a significant role in masticatory‐muscle stretch reflexes and in the integration of trigeminal proprioceptive information and its transmission to higher centers. © 1995 Wiley‐Liss, Inc.
This paper references
10.1007/BF00237931
Cerebellar afferents from the trigeminal sensory nuclei in the cat
R. Somana (2004)
10.1152/JN.1980.44.2.372
Intracellular analysis of synaptic potentials induced in trigeminal jaw-closer motoneurons by pontomesencephalic reticular stimulation during sleep and wakefulness.
S. Chandler (1980)
10.1002/CNE.902200303
Afferent projections to the oral motor nuclei in the rat
J. Travers (1983)
10.1002/CNE.902280212
The distribution of afferent neurones in the mesencephalic nucleus of the fifth nerve in the cat
S. Gottlieb (1984)
10.1152/jn.1963.26.3.379
Organization and function of the trigeminal mensencephalic nucleus.
C. Jerge (1963)
10.1113/jphysiol.1992.sp019320
Monosynaptic EPSPs elicited by single interneurones and spindle afferents in trigeminal motoneurones of anaesthetized rats.
P. Grimwood (1992)
10.1016/0304-3940(80)90333-X
Fibers of trigeminal mesencephalic neurons in the maxillary nerve of the rat
L. Gonzalo-Sanz (1980)
10.1016/0304-3959(86)90213-7
Convergence of cutaneous, tooth pulp, visceral, neck and muscle afferents onto nociceptive and non-nociceptive neurones in trigeminal subnucleus caudalis (medullary dorsal horn) and its implications for referred pain
B. Sessle (1986)
10.1016/0006-8993(84)90831-X
The ultrastructure of group Ia afferent fiber synapses in the lumbosacral spinal cord of the cat
R. E. W. Fyffe (1984)
10.1002/CNE.902680403
The central projection of masticatory afferent fibers to the trigeminal sensory nuclear complex and upper cervical spinal cord
Y. Shigenaga (1988)
10.1113/jphysiol.1972.sp009983
A functional analysis of the components of the mesencephalic nucleus of the fifth nerve in the cat
F. Cody (1972)
10.1159/000121784
Localization of cutaneously elicited climbing fiber responses in lobule V of the monkey cerebellum.
L. Robertson (1981)
10.1016/0006-8993(90)91285-O
Direct observations of synapses between GABA-immunoreactive boutons and muscle afferent terminals in lamina VI of the cat's spinal cord
D. Maxwell (1990)
10.1152/JN.1948.11.5.445
Anatomical considerations on monosynaptic reflex arcs.
J. Szentágothai (1948)
10.1016/0361-9230(90)90167-X
Convergence patterns of afferent information from the temporomandibular joint and masseter muscle in the trigeminal subnucleus caudalis
Y. Kojima (1990)
10.1002/CNE.902150405
Organization of HRP‐labeled trigeminal mandibular, primary afferent neurons in the rat
M. Jacquin (1983)
10.2170/JJPHYSIOL.20.1
Neurophysiologic properties of the supratrigeminal nucleus.
M. Takata (1970)
10.1113/jphysiol.1985.sp015890
Morphological and electrophysiological determination of the projections of jaw‐elevator muscle spindle afferents in rats.
K. Appenteng (1985)
10.1002/CNE.901730408
Projections to the spinal cord from medullary somatosensory relay nuclei
H. Burton (1977)
10.1002/CNE.901880107
Efferent connections of the brainstem trigeminal complex with the facial nucleus of the rat
R. Erzurumlu (1979)
10.1002/CNE.903530107
Inputs from identified jaw‐muscle spindle afferents to trigeminothalamic neurons in the rat: A double‐labeling study using retrograde HRP and intracellular biotinamide
P. Luo (1995)
10.1007/BF00227141
Upper cervical inspiratory neurons in the rat: an electrophysiological and morphological study
J. Lipski (2004)
10.1016/0006-8993(86)91148-0
The distribution of muscle primary afferents from the masseter nerve to the trigeminal sensory nuclei
T. Nishimori (1986)
10.1016/0006-8993(90)91632-Q
Morphology of central terminations of low-threshold trigeminal primary afferents from facial skin in the cat — intra-axonal staining with HRP
Y. Shigenaga (1990)
10.1002/CNE.903030210
Morphological characteristics and terminating patterns of masseteric neurons of the mesencephalic trigeminal nucleus in the rat: An intracellular horseradish peroxidase labeling study
P. Luo (1991)
10.1016/0006-8993(69)90266-2
Cortically induced presynaptic inhibition of trigeminal proprioceptive afferents.
E. Sauerland (1969)
10.1016/0014-4886(83)90094-8
Corticobulbar projections and orofacial and muscle afferent inputs of neurons in primate sensorimotor cerebral cortex
M. A. Sirisko (1983)
10.1002/CNE.903360105
Monosynaptic innervation of trigeminal motor neurones involved in mastication by neurones of the parvicellular reticular formation
D. Mogoseanu (1993)
10.1113/jphysiol.1963.sp007214
The response of de‐efferented muscle spindle receptors to stretching at different velocities
P. Matthews (1963)
10.1007/BF00236294
The medullary projection from the mesencephalic trigeminal nucleus. An experimental study with comments on the intrinsic trigeminal connections
F. Walberg (2004)
10.3109/08990229409028860
Physiological identification of jaw-movement-related neurons in the trigeminal nucleus of cats.
N. Capra (1994)
10.1016/0165-0270(92)90045-F
Intra-axonal neurobiotin™ injection rapidly stains the long-range projections of identified trigeminal primary afferents in vivo: comparisons with HRP and PHA-L
M. Jacquin (1992)
10.1016/0006-8993(89)90119-4
Physiological and morphological characteristics of periodontal mesencephalic trigeminal neurons in the cat — intra-axonal staining with HRP
Y. Shigenaga (1989)
10.1002/CNE.901390205
Trigeminal proprioceptive projections to the hypoglossal nucleus and the cervical ventral gray column
N. Mizuno (1970)
10.1152/JN.1940.3.5.423
FUNCTION OF MESENCEPHALIC ROOT OF FIFTH CRANIAL NERVE
K. Corbin (1940)
10.1016/0361-9230(92)90145-N
Responses of trigeminal subnucleus interpolaris neurons to afferent inputs from deep oral structures
Atsushi Ohya (1992)
10.1002/CNE.902060308
Reevaluation of projections from the mesencephalic trigeminal nucleus to the medulla and spinal cord: New projections. A combined retrograde and anterograde horseradish peroxidase study
D. Ruggiero (1982)
10.1016/0006-8993(82)90728-4
Origin of ascending intratrigeminal pathways in the cat
W. M. Panneton (1982)
10.1016/0306-4522(84)90018-6
Ascending and descending internuclear connections of the trigeminal sensory nuclei in the cat. A study with the retrograde and anterograde horseradish peroxidase technique
M. Ikeda (1984)
10.1016/0306-4522(89)90115-2
A quantitative study of the projections of the gracile, cuneate and trigeminal nuclei and of the medullary reticular formation to the thalamus in the rat
S. Kemplay (1989)
10.1016/0006-8993(88)91206-1
Morphology of single mesencephalic trigeminal neurons innervating masseter muscle of the cat
Y. Shigenaga (1988)
10.1016/0014-4886(74)90121-6
Oral-facial and jaw muscle afferent projections to neurons in cat frontal cortex.
J. Lund (1974)
10.1016/0014-4886(70)90209-8
Cerebellar projections of the masticatory and extraocular muscle proprioception.
G. B. Azzena (1970)
10.1523/JNEUROSCI.05-08-02095.1985
The ultrastructural basis for synaptic transmission between primary muscle afferents and neurons in Clarke's column of the cat
B. Walmsley (1985)
10.1152/JN.1984.51.5.890
Functional organization of trigeminal subnucleus interpolaris: nociceptive and innocuous afferent inputs, projections to thalamus, cerebellum, and spinal cord, and descending modulation from periaqueductal gray.
H. Hayashi (1984)
10.1113/jphysiol.1978.sp012353
The projection of jaw elevator muscle spindle afferents to fifth nerve motoneurones in the cat.
K. Appenteng (1978)
10.1016/0306-4522(82)90256-1
The cells of origin of the trigeminothalamic, trigeminospinal and trigeminocerebellar projections in the cat
M. Matsushita (1982)
10.1113/jphysiol.1980.sp013326
Activation of cat muscle spindle primary, secondary and intermediate sensory endings by suxamethonium.
M. Dutia (1980)
10.1002/CNE.903280108
Location, morphology, and central projections of mesencephalic trigeminal neurons innervating rat masticatory muscles studied by axonal transport of choleragenoid‐horseradish peroxidase
P. Raappana (1993)
10.1016/0006-8993(87)90506-3
Ascending and descending internuclear projections within the trigeminal sensory nuclear complex
I. D. Nasution (1987)
10.1016/0006-8993(82)90137-8
Physiological properties of neurons in different parts of the cat trigeminal sensory complex
J. Azérad (1982)
10.1016/0306-4522(91)90136-C
A comparison of the distribution and morphology of thalamic, cerebellar and spinal projection neurons in rat trigeminal nucleus interpolaris
K. Phelan (1991)
10.1016/0006-8993(91)90011-J
Monosynaptic connections between neurons of trigeminal mesencephalic nucleus and jaw-closing motoneurons in the rat: an intracellular horseradish peroxidase labelling study
P. Luo (1991)
10.1007/BF01063415
Functional properties of interneurons of the masticatory reflex
E. Gura (2005)
10.1002/CNE.901830112
Organization of trigeminothalamic tracts and other thalamic afferent systems of the brainstem in the rat: Presence of gelatinosa neurons with thalamic connections
T. Fukushima (1979)
10.1002/CNE.902630112
Central projections of the mesencephalic nucleus of the fifth nerve: An autoradiographic study
E. Luschei (1987)
10.1016/0006-8993(80)90756-8
Differential organization of thalamic projection cells in the brain stem trigeminal complex of the rat
R. Erzurumlu (1980)
10.1113/jphysiol.1992.sp019356
The classification of afferents from muscle spindles of the jaw‐closing muscles of the cat.
A. Taylor (1992)
10.1016/0006-8993(85)91442-8
Differential distribution of cell bodies and central axons of mesencephalic trigeminal nucleus neurons supplying the jaw-closing muscles and periodontal tissue: A transganglionic tracer study in the cat
S. Nomura (1985)
10.1016/0006-8993(85)91371-X
Distribution and response characteristics of masseteric nerve-driven neurons in two separate cortical projection areas of cats
K. Iwata (1985)
10.1002/CNE.902500205
Mesencephalic trigeminal sensory neurons of cat: Axon pathways and structure of mechanoreceptive endings in periodontal ligament
M. Byers (1986)
10.3109/07367228509144579
The dorsomedial portion of trigeminal nucleus oralis (Vo) in the rat: cytology and projections to the cerebellum.
W. Falls (1985)
10.1002/CNE.902360109
Trigeminal mesencephalic neurons innervating functionally identified muscle spindles and involved in the monosynaptic stretch reflex of the lateral pterygoid muscle of the guinea pig
S. Nozaki (1985)
10.1002/CNE.902150305
A light and electron microscopic study of premotor neurons for the trigeminal motor nucleus
N. Mizuno (1983)
10.1016/0006-8993(83)90928-9
The cells of origin of cat trigeminothalamic projections: Especially in the caudal medulla
Y. Shigenaga (1983)
10.1016/0006-8993(89)91573-4
An HRP study of the central projections from primary sensory neurons innervating the rat masseter muscle
J. Arvidsson (1989)
10.1016/0006-8993(94)90257-7
Immunohistochemical localization of glutamate and glutaminase in guinea pig trigeminal premotoneurons
J. Turman (1994)
10.1016/0306-4522(84)90066-6
Trigeminal afferents to the diencephalon in the rat
M. Peschanski (1984)
10.1002/CNE.902820306
Morphology of jaw‐muscle spindle afferents in the rat
D. Dessem (1989)
10.1002/CNE.902580307
Transneuronal transport of wheat germ agglutinin‐conjugated horseradish peroxidase into trigeminal interneurones of the rat
K. Appenteng (1987)
10.1016/0304-3940(81)90198-1
Peripheral and central distribution of fibres of the mesencephalic trigeminal root in the rat
C. Matesz (1981)
10.1016/0361-9230(93)90163-6
Thalamic- and cerebellar-projecting interpolaris neuron responses to afferent inputs
Atsushi Ohya (1993)
10.1016/0304-3940(78)90015-0
Trigeminal projections to cerebellar tactile areas in the rat-origin mainly from n. interpolaris and n. principalis
C. Watson (1978)
10.1016/0014-4886(81)90190-4
Response characteristics and classification of muscle spindles of the masseter muscle in the cat
H. Inoue (1981)
10.1159/000146232
Variations of supraorbital bony structures in Sienese skulls.
A. Guidotti (1986)
10.1113/jphysiol.1977.sp011709
Control of dynamic and static nuclear bag fibres and nuclear chain fibres by gamma and beta axons in isolated cat muscle spindels.
I. Boyd (1977)
10.1016/0006-8993(93)90601-I
An unrelayed projection of jaw-muscle spindle afferents to the cerebellum
R. Donga (1993)
10.1016/0006-8993(83)91330-6
Electron microscopic observations on the synaptic contacts of group Ia muscle spindle afferents in the cat lumbosacral spinal cord
S. Conradi (1983)
10.1002/CNE.901960202
Descending projections from the spinal and mesencephalic nuclei of the trigeminal nerve to the spinal cord in the cat. A study with the horseradish peroxidase technique
M. Matsushita (1981)
10.1016/0006-8993(79)90225-7
Neurons in marginal layer of trigeminal nucleus caudalis projecting to ventrobasal complex (VB) and posterior nuclear group (PO) demonstrated by retrograde labeling with horseradish peroxidase
Y. Shigenaga (1979)
10.1002/CNE.902790302
Distribution and central projections of primary afferent neurons that innervate the masseter muscle and mandibular periodontium: A double‐label study
N. Capra (1989)
10.1016/0006-8993(88)90732-9
Morphological and functional properties of trigeminal nucleus oralis neurons projecting to the trigeminal motor nucleus of the cat
Y. Shigenaga (1988)
10.1016/0006-8993(85)91308-3
Projections of the rat trigeminal sensory nuclear complex demonstrated by multiple fluorescent dye retrograde transport
J. Silverman (1985)



This paper is referenced by
10.1016/J.BRAINRESREV.2007.08.009
Neurobiology of orofacial proprioception
N. Lazarov (2007)
10.2186/PRP.5.143
Influence of Teeth Clenching on the Bodily Equilibrium against Striking Weight Impact
S. Tanaka (2006)
10.1002/cne.21047
Expression of vesicular glutamate transporter 1 immunoreactivity in peripheral and central endings of trigeminal mesencephalic nucleus neurons in the rat
Y. W. Pang (2006)
10.1523/JNEUROSCI.21-16-06298.2001
Quantitative Analysis of Synaptic Contacts Made between Functionally Identified Oralis Neurons and Trigeminal Motoneurons in Cats
A. Yoshida (2001)
10.1097/01.WNR.0000180149.29762.C4
Ultrastructure of jaw muscle spindle afferents within the rat trigeminal mesencephalic nucleus
S. Paik (2005)
10.14814/phy2.13206
Neurons within the trigeminal mesencephalic nucleus encode for the kinematic parameters of the whisker pad macrovibrissae
O. Mameli (2017)
10.1016/S0006-8993(01)02911-0
Light and electron microscopic observations of a direct projection from mesencephalic trigeminal nucleus neurons to hypoglossal motoneurons in the rat
J. Zhang (2001)
10.1016/j.neuroscience.2006.04.055
Brainstem projections from recipient zones of the anterior ethmoidal nerve in the medullary dorsal horn
W. Panneton (2006)
10.1016/S0006-8993(02)04046-5
Ultrastructural features of synapse from dorsal parvocellular reticular formation neurons to hypoglossal motoneurons of the rat
J. Zhang (2003)
10.1016/j.brainres.2005.06.074
Involvement of reticular neurons located dorsal to the facial nucleus in activation of the jaw-closing muscle in rats
J. Takamatsu (2005)
10.1016/j.pneurobio.2012.01.011
Generation of the masticatory central pattern and its modulation by sensory feedback
Philippe Morquette (2012)
10.1002/cne.1034
Jaw‐muscle spindle afferent pathways to the trigeminal motor nucleus in the rat
P. Luo (2001)
10.1002/(SICI)1096-9861(19990329)406:1<29::AID-CNE3>3.0.CO;2-0
Physiologic and morphologic properties of motoneurons and spindle afferents innervating the temporal muscle in the cat
A. Yoshida (1999)
10.1046/j.1460-9568.2000.00001.x
Evidence for functional compartmentalization of trigeminal muscle spindle afferents during fictive mastication in the rabbit
K. Westberg (2000)
10.1002/ar.20712
Peripheral Muscle Targets and Central Projections of the Mesencephalic Trigeminal Nucleus in Macaque Monkeys
N. Wang (2008)
10.1002/cne.21062
Selective distribution and function of primary afferent nociceptive inputs from deep muscle tissue to the brainstem trigeminal transition zone
H. Wang (2006)
10.1016/j.brainres.2018.02.033
Transcortical descending pathways through granular insular cortex conveying orofacial proprioception
Etsuko Ikenoue (2018)
10.1002/(SICI)1097-0185(199708)248:4<554::AID-AR7>3.0.CO;2-L
Central connections of the nucleus mesencephalicus nervi trigemini in the mallard (Anas platyrhynchosL.).
R. Bout (1997)
10.1523/JNEUROSCI.21-11-03729.2001
Membrane Resonance and Subthreshold Membrane Oscillations in Mesencephalic V Neurons: Participants in Burst Generation
N. Wu (2001)
10.1002/(SICI)1096-9861(19990412)406:3<384::AID-CNE7>3.0.CO;2-7
Ultrastructural anatomy of physiologically identified jaw‐muscle spindle afferent terminations onto retrogradely labeled jaw‐elevator motoneurons in the rat
P. Luo (1999)
10.1002/cne.21461
The derivatives of the Wnt3a lineage in the central nervous system
A. Louvi (2007)
10.1002/1096-9861(20001009)426:1<13::AID-CNE2>3.0.CO;2-R
Quantitative ultrastructure of physiologically identified premotoneuron terminals in the trigeminal motor nucleus in the cat
Y. Shigenaga (2000)
Membrane Excitability in Mesencephalic V Neurons Development of Inward Rectification and Control of
N. Wu (2015)
10.1016/S0892-1997(99)80057-5
Interrelation of mandibular laryngeal functions.
S. Cookman (1999)
10.1016/j.neuroscience.2016.03.026
Revisiting the supratrigeminal nucleus in the rat
T. Fujio (2016)
10.1002/(SICI)1097-0185(199607)245:3<581::AID-AR15>3.0.CO;2-L
Peptidergic innervation of the mesencephalic trigeminal nucleus in the cat
N. Lazarov (1996)
10.3791/2650
Physiological, morphological and neurochemical characterization of neurons modulated by movement.
D. Dessem (2011)
10.1111/j.1469-7793.1998.00695.x
Hyperpolarization‐activated cationic currents (Ih) in neurones of the trigeminal mesencephalic nucleus of the rat
B. Khakh (1998)
10.1152/JN.00850.2002
Development of inward rectification and control of membrane excitability in mesencephalic v neurons.
S. Tanaka (2003)
10.1016/j.neuroscience.2018.07.047
Cortical and Subcortical Projections from Granular Insular Cortex Receiving Orofacial Proprioception
Yumi Tsutsumi (2018)
10.1016/J.NEURES.2004.12.016
Excitatory GABAergic synaptic potentials in the mesencephalic trigeminal nucleus of adult rat in vitro
Y. Yokomizo (2005)
10.2334/josnusd.16-0845
Projection and synaptic connectivity of trigeminal mesencephalic nucleus neurons controlling jaw reflexes.
A. Yoshida (2017)
See more
Semantic Scholar Logo Some data provided by SemanticScholar