Online citations, reference lists, and bibliographies.
← Back to Search

“Apraxia Of Lid Opening,” A Focal Eyelid Dystonia: Clinical Study Of 32 Patients

P. Krack, M. H. Marion
Published 1994 · Medicine

Cite This
Download PDF
Analyze on Scholarcy
Share
We have seen 32 patients with “apraxia of lid opening” (ALO) in the following clinical settings: as an isolated condition (3 patients), idiopathic blepharospasm (BSP, 20 patients, including 4 familial cases), progressive supranuclear palsy (PSP, 7 patients), and dystonic parkinsonian syndrome (2 patients). Twenty‐nine patients treated with botulinum toxin into the orbicularis oculi muscle were rated before and after treatment and 83% of the patients improved on a clinical scale. Best results were obtained with injections directed toward the junction of the preseptal and pretarsal parts of the palpebral orbicularis oculi. Several patients also improved on anticholinergic drugs. Besides medical treatment, lid crutches, in conjunction with botulinum toxin injections, were useful in some patients. ALO is not a true apraxia; it constitutes an eyelid dystonia as shown by its clincal and electrophysiological features as well as pharmacological reactions and is encountered in a clinical spectrum ranging from an isolated from to predominant BSP. It was an important cause of treatment failures in botulinum toxin‐treated BSP but by modifying our injection strategy and by adding anticholinergic drugs and also lid crutches, we obtained a good functional benefit.
This paper references
10.1136/jnnp.55.5.369
A new variant of blepharospasm.
J. Elston (1992)
10.1038/eye.1988.4
Botulinum toxin therapy for involuntary facial movement
J. Elston (1988)
10.1016/S0002-9394(33)94251-8
Bilateral Facial Spasm: Paraspasme Facial Bilatéral of Sicard
H. Parker (1933)
10.1016/0013-4694(53)90037-6
The electrical activity of the muscles of the eye and eyelids in various positions and during movement.
A. Bjork (1953)
Die Encephalitis lethargica, ihre Nachkrankheiten und ihre Behandlung
C. Economo (1929)
10.1097/00005053-195603000-00001
LEFT HEMIPLEGIA AND MOTOR IMPERSISTENCE
M. Fisher (1956)
10.1098/rspl.1898.0090
On the reciprocal innervation of antagonistic muscles. Fifth note
C. Sherrington (1899)
10.1001/ARCHOPHT.1965.00970030157003
APRAXIA OF LID OPENING.
J. Goldstein (1965)
10.1212/WNL.36.3.414
Eyelid movement disorders and motor impersistence in acute hemisphere disease
E. De Renzi (1986)
10.1212/WNL.35.3.423
“Apraxia” of eyelid opening
F. E. Lepore (1985)
10.1002/ANA.410250615
Apraxia of eyelid opening secondary to right hemisphere infarction
J. C. Johnston (1989)
10.1001/ARCHNEURPSYC.1927.02210030107008
PAROXYSMAL SPASM OF THE EYELIDS AS A POST-ENCEPHALITIC MANIFESTATION
B. J. Alpers (1927)
10.1136/jnnp.51.6.767
Blepharospasm: a review of 264 patients.
F. Grandas (1988)
10.1016/0022-510X(88)90191-8
Involuntary closure of eyelids in parkinsonism: Electrophysiological evidence for prolonged inhibition of the levator palpebrae muscles
Á. Esteban (1988)
10.1002/MDS.870040402
Eyelid movement abnormalities in progressive supranuclear palsy
Lawrence I. Golbe (1989)
10.1177/095952877906200129
The Movements of the Eyelids
Gowers Wr (1879)



This paper is referenced by
10.3109/9780203640487-10
Other primary generalized dystonias
A. Elia (2007)
10.1097/WNO.0b013e3180334f0b
Modified Lundie Loops Improve Apraxia of Eyelid Opening
B. Ramasamy (2007)
10.1002/mds.22116
GPi‐DBS in Huntington's disease: Results on motor function and cognition in a 72‐year‐old case
A. Fasano (2008)
10.1016/S0003-9993(97)90169-6
Botulinum toxin treatment of apraxia of eyelid opening in progressive supranuclear palsy: report of two cases.
F. Piccione (1997)
10.1016/S1567-4231(09)70189-3
Chapter 41 Focal injection therapy
Jean-Michel Gracies (2003)
10.3233/NRE-151220
Bilateral ptosis: Lesion in the oculomotor nuclei or supranuclear lesion?
Julien Dimitriou (2015)
10.1016/j.parkreldis.2016.12.009
Understanding falls in progressive supranuclear palsy.
B. Bluett (2017)
10.1590/S0004-282X2005000200006
Botulinum toxin a in the treatment of blepharospasm: a 10-year experience.
L. Silveira-Moriyama (2005)
Tricks in dystonia : ordering the complexity Vesper Fe
M. Ramos (2014)
10.1007/s00702-010-0546-9
Difficulties with differentiating botulinum toxin treatment effects in essential blepharospasm
B. Wabbels (2010)
10.7916/D8SQ8Z4T
Blepharospasm plus Cervical Dystonia with Predominant Anterocollis: A Distinctive Subphenotype of Segmental Craniocervical Dystonia
O. Waln (2011)
10.1007/s40263-016-0347-2
A Review of Treatment Options for Progressive Supranuclear Palsy
M. Stamelou (2016)
10.1016/S0002-9394(01)01389-7
Prolonged orbicularis oculi activity: A major factor in apraxia of lid opening
V. Tozlovanu (2001)
10.1007/978-1-4614-4466-4_16
Spastic Facial Muscle Disorders
Juwan Park (2012)
10.1038/sj.eye.6702054
Blepharospasm and hemifacial spasm: a protocol for titration of botulinum toxin dose to the individual patient and for the management of refractory cases
E. Ortisi (2006)
10.1007/s00415-006-7003-6
Dystonia in Parkinson’s disease
E. Tolosa (2006)
10.1016/j.neurol.2017.05.006
123I-FP-CIT SPECT imaging in blepharospasm.
M. De Verdal (2017)
10.1016/J.MEHY.2007.03.014
Dystonia redefined as central non-paretic loss of control of muscle action: a concept including inability to activate muscles required for a specific movement, or 'negative dystonia'.
T. Mezaki (2007)
10.1097/ICU.0b013e3282be9032
What is new in the era of focal dystonia treatment? Botulinum injections and more
A. Çetinkaya (2007)
10.1080/01658107.2018.1474371
Awakening Ptosis: A Clinical Review
A. I. Otaiku (2019)
10.1212/WNL.48.5.1178
International Symposium for Therapy of Ocular Motility and Related Visual Disturbances
H. Kaminski (1997)
10.1016/S1353-8020(01)00025-6
Dystonia and parkinsonism.
J. Jankovic (2001)
10.18821/1560-9545
Поражение периферических нервов паранеопластического и токсического генеза у пациентов, страдающих раком молочной железы и мелкоклеточным раком легкого
Array С. Королева (2013)
10.1212/WNL.48.6.1491
Apraxia of lid opening
D. Boghen (1997)
10.1002/mds.20957
Deep brain stimulation: Postoperative issues
G. Deuschl (2006)
Electrophysiologic Evaluation of Blepharospasm
Jae-Myun Chung (1999)
10.1097/WNO.0000000000000512
Sleep-Induced Apraxia of Eyelid Opening
S. Reggie (2017)
10.1002/mds.10163
Postoperative management of subthalamic nucleus stimulation for Parkinson's disease
P. Krack (2002)
10.1017/CBO9780511544873.045
Progressive Supranuclear Palsy.
L. Golbe (2001)
10.1038/eye.2000.86
Riolan's muscle: Action and indications for botulinum toxin injection
I. Mackie (2000)
10.1007/s00417-003-0682-0
Glucose hypometabolism in medial frontal cortex of patients with apraxia of lid opening
Y. Suzuki (2003)
10.1016/S1293-2965(07)70755-7
Aspectos terapéuticos actuales de la toxina botulínica en neurología
S. Sangla (2007)
See more
Semantic Scholar Logo Some data provided by SemanticScholar