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Gold Nanoparticle-fluorophore Complexes: Sensitive And Discerning "noses" For Biosystems Sensing.

Uwe H F Bunz, Vincent M Rotello
Published 2010 · Medicine, Chemistry
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Gold nanoparticles (NPs) efficiently quench adsorbed fluorophores. Upon disruption of such complexes by an analyte, fluorescence turn-on is observed. By judicious choice of the functionalized NP and the fluorophore, these complexes display different responses to analytes, thus leading to versatile yet simple array-based sensor platforms. Using this strategy, we can identify proteins in buffer and serum, distinguish between both different species and different strains of bacteria, and differentiate between healthy, cancerous, and metastatic human and murine cells.
This paper references
10.1021/jo0617971
Supramolecular analytical chemistry.
Eric V. Anslyn (2007)
10.1021/ar020083j
Nanoparticles: scaffolds and building blocks.
Roy Shenhar (2003)
10.1021/ja027184x
Influencing receptor-ligand binding mechanisms with multivalent ligand architecture.
Jason E. Gestwicki (2002)
10.1038/nnano.2007.99
Detection and identification of proteins using nanoparticle-fluorescent polymer 'chemical nose' sensors.
Chang-Cheng You (2007)
10.1002/ange.200805456
Konjugierte Polyelektrolyte: Synthese, Photophysik und Anwendungen
Hui Jiang (2009)
10.1002/chem.200306076
Nanoparticles: scaffolds for molecular recognition.
Ulf Drechsler (2004)
10.1073/pnas.0900975106
Detection and differentiation of normal, cancerous, and metastatic cells using nanoparticle-polymer sensor arrays
Avinash Bajaj (2009)
10.1039/B811603B
Gold nanoparticle-PPE constructs as biomolecular material mimics: understanding the electrostatic and hydrophobic interactions
Ronnie L. Phillips (2009)
10.1021/jo900433j
Guidelines for pattern recognition using differential receptors and indicator displacement assays.
Masanori Kitamura (2009)
10.1021/MA8016025
Sugar-Substituted Poly(p-phenyleneethynylene)s: Sensitivity Enhancement toward Lectins and Bacteria
Ronnie L. Phillips (2008)
10.1016/j.ccr.2006.04.009
Indicator-displacement assays
Binh T. Nguyen (2006)
10.1002/chem.200800296
Hydroxycruciforms: amine-responsive fluorophores.
Psaras L McGrier (2008)
10.1021/jf0624695
Colorimetric sensor array for soft drink analysis.
Chen Zhang (2007)
10.1021/ol071065a
A food freshness sensor using the multistate response from analyte-induced aggregation of a cross-reactive poly(thiophene).
Marc S. Maynor (2007)
10.1021/ja052606z
A colorimetric sensor array for organics in water.
Chen Zhang (2005)
10.1002/anie.200703369
Rapid and efficient identification of bacteria using gold-nanoparticle-poly(para-phenyleneethynylene) constructs.
Ronnie L. Phillips (2008)
10.1021/ja061112e
Cruciforms as functional fluorophores: response to protons and selected metal ions.
Anthony J. Zucchero (2006)
10.1021/ma9812332
Evidence of Aggregate Formation for 2,5-Dialkylpoly(p-phenyleneethynylenes) in Solution and Thin Films
Carrie E. Halkyard (1998)
10.1007/s002160050875
Non-selective chemical sensors in analytical chemistry: from “electronic nose” to “electronic tongue”
Yuri Vlasov (1998)
10.1038/212901a0
Effect of Pyrophosphate on Hydroxyapatite and Its Implications in Calcium Homeostasis
Herbert Fleisch (1966)
10.1039/B505518K
Differential receptor arrays and assays for solution-based molecular recognition.
Aaron T Wright (2006)
10.1021/la051152g
Nonspecific interactions of a carboxylate-substituted PPE with proteins. A cautionary tale for biosensor applications.
Ik-Bum Kim (2005)
10.1016/S1074-5521(96)90280-X
Strength in numbers: non-natural polyvalent carbohydrate derivatives.
Laura L Kiessling (1996)
10.1024/0301-1526.30.S58.15
The fate of the ischaemic limb in diabetes: it is neuropathy that makes the difference
E. Chantelau (2001)
10.1021/cr970071p
Programmed Materials Synthesis with DNA.
James J. Storhoff (1999)
10.1021/ja904045n
Pattern-based recognition of thiols and metals using a single squaraine indicator.
Himali Sudarshani Hewage (2009)
10.1002/ANGE.200703369
Effiziente Erkennung von Bakterien mit Goldnanopartikel‐Poly(para‐phenylenethinylen)‐Konstrukten
Ronnie L. Phillips (2008)
10.1038/35021028
A colorimetric sensor array for odour visualization
Neal A. Rakow (2000)
10.1002/chem.200801403
Nano-conjugate fluorescence probe for the discrimination of phosphate and pyrophosphate.
Ik-Bum Kim (2009)
10.1002/anie.200351058
A multicomponent sensing ensemble in solution: differentiation between structurally similar analytes.
Sheryl Lynn Wiskur (2003)
10.1002/(SICI)1521-3757(19981016)110:20<2908::AID-ANGE2908>3.0.CO;2-2
Polyvalente Wechselwirkungen in biologischen Systemen: Auswirkungen auf das Design und die Verwendung multivalenter Liganden und Inhibitoren
Mathai Mammen (1998)
10.1038/nmat768
Conducting polymers in electronic chemical sensors
Jiri Janata (2003)
10.1021/cr030698+
Gold nanoparticles: assembly, supramolecular chemistry, quantum-size-related properties, and applications toward biology, catalysis, and nanotechnology.
Marie-Christine Daniel (2004)
10.1021/ja0468022
Colorimetric molecularly imprinted polymer sensor array using dye displacement.
Nathaniel T Greene (2005)
10.1073/pnas.1132025100
Beyond superquenching: Hyper-efficient energy transfer from conjugated polymers to gold nanoparticles
Chunhai Fan (2003)
10.1021/nl0727056
Targeted photothermal lysis of the pathogenic bacteria, Pseudomonas aeruginosa, with gold nanorods.
R Sean Norman (2008)
10.1039/b410889b
Surface recognition of biomacromolecules using nanoparticle receptors.
Ayush Verma (2005)
10.1006/bbrc.2002.6678
The SELDI-TOF MS approach to proteomics: protein profiling and biomarker identification.
Haleem J. Issaq (2002)
10.1039/b416587j
Mannose-substituted PPEs detect lectins: a model for Ricin sensing.
Ik-Bum Kim (2005)
10.1002/chem.200400788
Sugar-poly(para-phenylene ethynylene) conjugates as sensory materials: efficient quenching by Hg2+ and Pb2+ ions.
Ik-Bum Kim (2004)
10.1002/pi.2206
Colorimetric and fluorometric molecularly imprinted polymer sensors and binding assays
Clifton J. Stephenson (2007)
10.1128/AAC.46.7.2155-2161.2002
Multiplex PCR Strategy for Rapid Identification of Structural Types and Variants of the mec Element in Methicillin-Resistant Staphylococcus aureus
Duarte Oliveira (2002)
10.1021/ar9600796
Teaching old indicators new tricks.
Sheryl Lynn Wiskur (2001)
10.1021/cr980102w
Cross-reactive chemical sensor arrays.
Keith J. Albert (2000)
10.1021/ja00155a023
Fluorescent Chemosensors Based on Energy Migration in Conjugated Polymers: The Molecular Wire Approach to Increased Sensitivity
Qin Yuan Zhou (1995)
10.1128/jcm.37.6.2024-2026.1999
Times to Detection of Bacteria and Yeasts in BACTEC 9240 Blood Culture Bottles
Barbara S. Reisner (1999)
10.1021/ja00032a046
Antibody targeting to bacterial cells using receptor-specific ligands
Carolyn R. Bertozzi (1992)
10.1039/B109895K
Detection of infectious and toxigenic bacteria.
Anil K. Deisingh (2002)
10.1021/cr068287r
Serum and plasma proteomics.
Haleem J. Issaq (2007)
10.1016/S0140-6736(88)92659-1
DETECTION OF HTV1 DNA IN INFANTS AND CHILDREN BY MEANS OF THE POLYMERASE CHAIN REACTION
Francoise Claudine Laure (1988)
10.1021/ja047936i
Detection of bacteria with carbohydrate-functionalized fluorescent polymers.
Matthew D. Disney (2004)
10.1021/ja056428l
Deposition of CTAB-terminated nanorods on bacteria to form highly conducting hybrid systems.
Vikas Berry (2005)
10.1038/nchem.334
Sensing of proteins in human serum using conjugates of nanoparticles and green fluorescent protein.
Mrinmoy De (2009)
10.1002/(SICI)1521-3773(19981102)37:20<2754::AID-ANIE2754>3.0.CO;2-3
Polyvalent Interactions in Biological Systems: Implications for Design and Use of Multivalent Ligands and Inhibitors.
Mathai Mammen (1998)
10.1002/1521-3773(20010917)40:18<3337::AID-ANIE3337>3.0.CO;2-G
Not a Library
Roald Hoffmann (2001)
10.1021/cr030067f
Nanostructures in biodiagnostics.
Nathaniel L Rosi (2005)
10.1016/S1367-5931(99)00034-4
Anion recognition: synthetic receptors for anions and their application in sensors.
Timothy S. Snowden (1999)
10.1021/ma050595o
Sensing of lead ions by a carboxylate-substituted PPE : Multivalency effects
Ik-Bum Kim (2005)
10.1021/ja0200903
Selective binding of mannose-encapsulated gold nanoparticles to type 1 pili in Escherichia coli.
Chun-Cheng Lin (2002)
10.1002/anie.200805456
Conjugated polyelectrolytes: synthesis, photophysics, and applications.
Hui Jiang (2009)
10.1021/cr9603744
The Cationminus signpi Interaction.
Jennifer C. Ma (1997)



This paper is referenced by
10.1002/chem.201803103
Immobilized Poly(aryleneethynylene) pH Strips Discriminate Different Brands of Cola.
Markus Bender (2018)
10.1039/c3nr06583a
A universal fluorescence sensing strategy based on biocompatible graphene quantum dots and graphene oxide for the detection of DNA.
Zhao Sheng Qian (2014)
10.1021/la300402w
Physicochemical characteristics of protein-NP bioconjugates: the role of particle curvature and solution conditions on human serum albumin conformation and fibrillogenesis inhibition.
Sonia Goy-López (2012)
10.1002/smll.201202772
Pattern recognition analysis of proteins using DNA-decorated catalytic gold nanoparticles.
Xiafeng Yang (2013)
10.1016/j.biomaterials.2014.05.054
Scavenger receptor-recognized and enzyme-responsive nanoprobe for fluorescent labeling of lysosomes in live cells.
Yanbin Fan (2014)
10.1016/J.CCR.2018.03.019
Two-photon absorption properties of 1,10-phenanthroline-based Ru(II) complexes and related functionalized nanoparticles for potential application in two-photon excitation photodynamic therapy and optical power limiting
Gilles Lemercier (2018)
10.1021/acs.analchem.5b02453
Suspension Array of Ionic Liquid or Ionic Liquid-Quantum Dots Conjugates for the Discrimination of Proteins and Bacteria.
Shuai X. Chen (2015)
10.1021/acsami.6b06462
Water-Soluble Poly(p-aryleneethynylene)s: A Sensor Array Discriminates Aromatic Carboxylic Acids.
Jinsong Han (2016)
10.1016/B978-0-12-409547-2.12616-2
Colorimetric and Fluorometric Sensor Arrays for Molecular Recognition
Jon R. Askim (2017)
10.1039/c1cc14726a
Mapping the nanoparticle-coating monolayer with NMR pseudocontact shifts.
Gaetano Guarino (2012)
10.1016/j.colsurfb.2018.09.070
Biocompatible graphene-based nanoagent with NIR and magnetism dual-responses for effective bacterial killing and removal.
Fan Yang (2019)
10.1007/s11426-018-9374-y
Using selenium-conjugated polyethylene glycol to enhance the stability of gold nanoparticles in biologically relevant samples
Yang Xue (2018)
10.1002/mabi.201900415
Nanoparticles Based on Hydrophobic Polysaccharide Derivatives-Formation Principles, Characterization Techniques, and Biomedical Applications.
Martin Gericke (2020)
10.1007/s12272-013-0273-5
Gold nanoparticle (AuNP)-based drug delivery and molecular imaging for biomedical applications
Eun Hye Jeong (2014)
10.1039/c0nr00612b
DNA-mediated site-specific deposition of gold nanoparticles on silicon wafers.
Katharina Heimann (2010)
10.1021/la202035x
Aging of gold nanoparticles: ligand exchange with disulfides.
Yun Ma (2011)
10.1039/c4cp01534g
A 5-(difluorenyl)-1,10-phenanthroline-based Ru(II) complex as a coating agent for potential multifunctional gold nanoparticles.
Juliette Moreau (2014)
10.1021/acs.langmuir.5b04568
Structure of Rigid Polymers Confined to Nanoparticles: Molecular Dynamics Simulations Insight.
Sabina Maskey (2016)
10.1016/J.CHEMPR.2017.05.005
Array-Based Sensing of Whisky: A Whiff of the Spirit World
Puspam Keshri (2017)
10.1039/C8TB02349B
NIR-Absorbing water-soluble conjugated polymer dots for photoacoustic imaging-guided photothermal/photodynamic synergetic cancer therapy.
Huaxia Shi (2018)
10.1007/978-3-642-36199-9_41-1
Poly(Arylene Ethynylene)s
Akshay Kokil (2014)
10.1002/9783527656028.CH06
Materials for FRET Analysis: Beyond Traditional Dye–Dye Combinations
K. E. Sapsford (2013)
10.1039/c2an35170f
Label-free Raman spectroscopy for accessing intracellular anticancer drug release on gold nanoparticles.
Kwang-Su Ock (2012)
10.1039/c0cc03900d
Fluorescent nanoparticles assembled from a poly(ionic liquid) for selective sensing of copper ions.
Kun Cui (2011)
10.1016/j.jhazmat.2019.121118
Fluorescent carbon nanodots-based artificial tongue for determining and discriminating cigarettes.
Naiying Du (2019)
10.1039/c9cc01741k
A repertoire of biomedical applications of noble metal nanoparticles.
Mohammad Azharuddin (2019)
10.1039/c6an02647h
Recent developments in protease activity assays and sensors.
Irvine Lian Hao Ong (2017)
10.1039/C4TB00252K
Using metal nanoparticles as a visual sensor for the discrimination of proteins.
Hai Yan Liu (2014)
10.1021/MA5018296
Syntheses and Characteristics of Water-Soluble, Pyridine-Based Poly(aryleneethynylene)s
Kai Seehafer (2014)
Personalized Diagnosis and Therapy
G€unter M€uller (2015)
10.1039/c3cs60277j
Functional nanoprobes for ultrasensitive detection of biomolecules: an update.
Jing-Juan Xu (2014)
10.1021/ja305814u
A graphene-based sensor array for high-precision and adaptive target identification with ensemble aptamers.
Hao Pei (2012)
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