Online citations, reference lists, and bibliographies.
← Back to Search

Challenging Regulations: Managing Risks In Crop Biotechnology

H. Jones
Published 2015 · Biology, Medicine

Save to my Library
Download PDF
Analyze on Scholarcy Visualize in Litmaps
Reduce the time it takes to create your bibliography by a factor of 10 by using the world’s favourite reference manager
Time to take this seriously.
Get Citationsy
Alongside other aspects of agriculture, plant breeding is pivotal to securing crop yields necessary to meet the growing demands for human food and animal feed. In addition to the important targets of yield, nutritional quality and resilience to abiotic stresses, breeding for resistance to pests and diseases will become even more critical as the availability of plant protection products is further diminished by regulation and/or the lack of new active ingredients coming to market (Chapman 2014) and by consumer preferences for fewer inputs. In this regard, it is fortuitous and timely that future crop genetic improvement will be aided by several developments in plant breeding that are underpinned by the massive increase in DNA sequence information flowing into databases from new methods of reading DNA that were developed in the mid 2000's (Moorthie et al. 2011). A stark example of this revolution in sequencing speed is seen in the progress of rice genomics where, after about three years work, the first draft genomic sequence of rice was published in 2002 (Goff et al. 2002; Yu et al. 2002). Yet, little over ten years later, IRRI published the genomic sequence of 3000 different rice varieties (Alexandrov 2015). This step‐change in sequencing and bioinformatics resulted in the generation of massive data sets that can be mined to give information about the genetic location and function of specific alleles which in turn can be used to inform and facilitate crop improvement via conventional breeding methods or via a spectrum of rapidly evolving molecular breeding technologies and concepts of synthetic biology. Two such technologies close to commercialization are genome editing and interorganism silencing which are discussed below. However, the plant breeder faces significant challenges to fully integrate these novel approaches to produce new varieties because of ambiguities and uncertainties surrounding risk assessment and regulation.
This paper references
Duplications That Suppress and Deletions That Restore Expression from a Chalcone Synthase Multigene Family.
J. Todd (1996)
The Canadian Food Inspection Agency.
D. Hare (1997)
Directive 2001 / 18 / EC of the European Parliament and of the Council of 12 March 2001 on the Deliberate Release into the Environment of Genetically Modifi ed Organisms ( EEC , 2001 )
S. A. Goff (2001)
Directive 2001/18/EC of the European Parliament and of the Council of 12 March 2001 on the Deliberate Release into the Environment of Genetically
European Parliament (2001)
A draft sequence of the rice genome (Oryza sativa L. ssp. japonica).
S. Goff (2002)
A Draft Sequence of the Rice Genome (Oryza sativa L. ssp. indica)
Jun Yu (2002)
Transgenic rootstock protein transmission in grapevines
M. Dutt (2007)
Proceedings of the International Symposium on Biotechnology of Temperate Fruit Crops and Tropical Species
R. Scorza (2007)
Review of massively parallel DNA sequencing technologies
S. Moorthie (2011)
Scientific opinion addressing the safety assessment of plants developed through cisgenesis and intragenesis
H. Andersson (2012)
Trait stacking via targeted genome editing.
W. M. Ainley (2013)
Intragenesis and cisgenesis as alternatives to transgenic crop development.
I. Holme (2013)
Determination of the Safety of Cibus Canada Inc. ' s Canola (Brassica napus L
Genetically modifi ed plants and regulatory loopholes and weaknesses under the plant protection act
E. Montgomery (2013)
Genetically modifi ed plants and regulatory loopholes and weaknesses under the plant protection act
S. Moorthie (2013)
Is the regulatory regime for the registration of plant protection products in the EU potentially compromising food security
P. Chapman (2014)
Simultaneous editing of three homoeoalleles in hexaploid bread wheat confers heritable resistance to powdery mildew
Sulfonylurea - tolerant canola eyed for 2016 launch
W. M. Ainley (2014)
Sulfonylurea-tolerant canola eyed for
Agcanada News (2014)
Regulatory uncertainty over genome editing.
H. Jones (2015)
SNP-Seek database of SNPs derived from 3000 rice genomes
N. Alexandrov (2014)
Plants with Novel Traits
P. Chapman (2015)
Plants with Novel Traits Available via plants-with-novel-traits/eng
Office of Science and Technology Policy (OSTP)
Yael Kovo (2016)
Available via plants-with-novel-traits/approved-under-review/decision- documents/dd-2013-100
on the Deliberate Release into the Environment of Genetically Modifi ed Organisms
European Parliament
Figure 1 . Three processes, with examples that have generated commercial herbicide tolerant crops and the EU GMO regulatory implications. Event 5715

This paper is referenced by
Cisgenesis: Engineering Plant Genome by Harnessing Compatible Gene Pools
B. K. Sarmah (2021)
Evolution of regulatory systems and national biosafety frameworks
R. Hull (2021)
CRISPR-Cas9 in agriculture: Approaches, applications, future perspectives, and associated challenges
Prabin Adhikari (2020)
Plant Genome Editing – Policies and Governance
T. Sprink (2020)
Plants Developed by New Genetic Modification Techniques—Comparison of Existing Regulatory Frameworks in the EU and Non-EU Countries
M. Eckerstorfer (2019)
An EU Perspective on Biosafety Considerations for Plants Developed by Genome Editing and Other New Genetic Modification Techniques (nGMs)
M. Eckerstorfer (2019)
Edit at will: Genotype independent plant transformation in the era of advanced genomics and genome editing.
A. Kausch (2019)
Increasing metabolic potential: C-fixation.
P. Andralojc (2018)
Genome editing in crop improvement: Present scenario and future prospects
G. S. Miglani (2017)
Potential impact of genome editing in world agriculture.
Jorge Martínez-Fortún (2017)
Genetic improvement of grass pea (Lathyrus sativus) for low β-L-ODAP content
P. Emmrich (2017)
Future of breeding by genome editing is in the hands of regulators.
H. Jones (2015)
Genome editing for crop improvement: Challenges and opportunities.
N. Abdallah (2015)
Semantic Scholar Logo Some data provided by SemanticScholar