Online citations, reference lists, and bibliographies.

Cytogenetic Analysis Of Tissues From Patients With Familial Paragangliomas Of The Head And Neck

A. Zaslav, D. Myssiorek, C. Mucia, J. Fox
Published 1995 · Medicine

Cite This
Download PDF
Analyze on Scholarcy
Background. Paragangliomas of the head and neck are slow‐growing tumors that originate from neural crest cells. Between 7% and 9% of these tumors have a familial occurrence. The suspected gene for familial paragangliomas (FP) is transmitted with an autosomal dominant mode of inheritance with incomplete penetrance, and appears to exhibit genomic imprinting. It has been demonstrated by family studies that individuals who inherit the gene(s) from their father will develop the disease. Through linkage analysis, the gene(s) for FP has been postulated to be located on the long arm of chromosome 11. The discovery of many different genes has been elucidated through the cytogenetic analysis of affected individuals who carry specific chromosome aberrations. This project was designed to look for chromosome abnormalities in several second‐generation family members to further assist in the localization of the gene(s) for FP.

This paper is referenced by
Lessons to be learned: a case study approach Paraganglioma of the urinary bladder
M. Dewan (2001)
Carotid body tumors in inhabitants of altitudes higher than 2000 meters above sea level
S. Rodríguez-Cuevas (1998)
[Head and neck paragangliomas: imaging diagnosis and embolization].
A. C. Rodríguez (2007)
From the archives of the AFIP. Paragangliomas of the head and neck: radiologic-pathologic correlation. Armed Forces Institute of Pathology.
A. B. Rao (1999)
Imaging Evaluation and Treatment of Vascular Lesions at the Skull Base.
Gaurav Jindal (2017)
Familial paraganglioma and gastric stromal sarcoma: a new syndrome distinct from the Carney triad.
J. Carney (2002)
Paragangliomas de cabeza y cuello: diagnstico por imagen y embolizacin
A. M. C. Rodríguez (2007)
Repositioning the hereditary paraganglioma critical region on chromosome band 11q23
B. Baysal (1999)
Embolization of vascular tumors of the head and neck.
J. Gemmete (2009)
Gastric stromal sarcoma, pulmonary chondroma, and extra-adrenal paraganglioma (Carney Triad): natural history, adrenocortical component, and possible familial occurrence.
J. Carney (1999)
Paragangliomas of the head and neck: clinical, morphological and immunohistochemical aspects.
P. A. Filho (2001)
Semantic Scholar Logo Some data provided by SemanticScholar