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Multifunctional Poly(2-oxazoline) Nanoparticles For Biological Applications.

Kristian Kempe, Antje Vollrath, Hendrik W Schaefer, T. Poehlmann, C. Biskup, R. Hoogenboom, S. Hornig, U. Schubert
Published 2010 · Materials Science, Medicine

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New multifunctional copoly(2-oxazoline) nanoparticles were prepared for cell studies. The polymer contains double-bond side chains as potential reaction sites for "thio"-click reactions as well as a fluorescein label covalently bound to the polymer backbone. Using the nanoprecipitation technique, spherical nanoparticles of 200-800 nm were obtained. Confocal laser scanning microscopy measurements revealed the cellular uptake of the nanoparticles.
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