← Back to Search
Detection And Inhibition Of Bacteria On A Dual-Functional Silver Platform.
Vadanasundari Vedarethinam, L. Huang, W. Xu, R. Zhang, Deepanjali D Gurav, Xuming Sun, J. Yang, R. Chen, Kun Qian
Published 2019 · Materials Science, Chemistry, Medicine
Download PDFAnalyze on Scholarcy
Detection and inhibition of bacteria are universally required in clinics and daily life for health care. Developing a dual-functional material is challenging and in demand, engaging advanced applications for both defined bioanalysis and targeted biotoxicity. Herein, magnetic silver nanoshells are designed as a multifunctional platform for the detection and inhibition of bacteria. The optimized magnetic silver nanoshells enable direct laser desorption/ionization mass spectrometry based metabolic analysis of bacteria (≈10 µL-1 ), in complex biofluids. The serum infection process (0-10 h) is monitored by statistics toward clinical classification. Moreover, magnetic silver nanoshells facilitate surface adhesion on bacteria due to nanoscale surface roughness and thus display long-term antibacterial effects. Bacteria metabolism is studied with metabolic biomarkers (e.g., malate and lysine) identified during inhibition, showing cell membrane destruction and dysfunctional protein synthesis mechanisms. This work not only guides the design of material-based approaches for bioanalysis and biotoxicity, but contributes to bacteria-related diagnosis by using specific metabolic biomarkers for sensitive detection and new insights by monitoring metabolomic change of bacteria for antibacterial applications.
This paper references
Current evidence on hospital antimicrobial stewardship objectives: a systematic review and meta-analysis.
Emelie C. Schuts (2016)
Extraction, detection, and profiling of serum biomarkers using designed Fe3O4@SiO2@HA core–shell particles
C. Rejeeth (2017)
Visible-light-driven enhanced antibacterial and biofilm elimination activity of graphitic carbon nitride by embedded Ag nanoparticles
Wei Bing (2015)
Nanotechnology-Driven Therapeutic Interventions in Wound Healing: Potential Uses and Applications
Suzana Hamdan (2017)
Bactericidal activity of partially oxidized nanodiamonds.
Julia Wehling (2014)
An "On-Site Transformation" Strategy for Treatment of Bacterial Infection.
Guobin Qi (2017)
Efficient hot-electron transfer by a plasmon-induced interfacial charge-transfer transition
K. Wu (2015)
Antimicrobial susceptibility testing using high surface-to-volume ratio microchannels.
C. H. Chen (2010)
Synthesis of Fe(3)O(4)@SiO(2)@PMMA core-shell-shell magnetic microspheres for highly efficient enrichment of peptides and proteins for MALDI-ToF MS analysis.
H. Chen (2010)
Characterization of Protein Lysine Propionylation in Escherichia coli: Global Profiling, Dynamic Change, and Enzymatic Regulation.
Mingwei Sun (2016)
Designed Microdevices for In Vitro Diagnostics
Xuming Sun (2017)
Engineering Iron Oxide Hollow Nanospheres to Enhance Antimicrobial Property: Understanding the Cytotoxic Origin in Organic Rich Environment
Y. A. Nor (2016)
Self-assembling dipeptide antibacterial nanostructures with membrane disrupting activity
Lee Schnaider (2017)
Plasmonic silver nanoshells for drug and metabolite detection
L. Huang (2017)
High-efficiency nano/micro-reactors for protein analysis
Yixin Li (2015)
Sensing by Smell: Nanoparticle-Enzyme Sensors for Rapid and Sensitive Detection of Bacteria with Olfactory Output.
Bradley M. Duncan (2017)
Structure transition, formation, and optical absorption property study of Ag/SiO 2 nanofilm by sol–gel method
Yan Li (2012)
Nanomaterials as Assisted Matrix of Laser Desorption/Ionization Time-of-Flight Mass Spectrometry for the Analysis of Small Molecules
M. Lu (2017)
Potential of marine natural products against drug-resistant fungal, viral, and parasitic infections.
U. R. Abdelmohsen (2017)
Magnetic Field-Induced T Cell Receptor Clustering by Nanoparticles Enhances T Cell Activation and Stimulates Antitumor Activity
Karlo Perica (2014)
WHO Global Antimicrobial Resistance Surveillance System early implementation 2016-17.
Barbara Tornimbene (2018)
Effect of the Volume-to-Surface Ratio of Cultures on Escherichia coli Growth: An Experimental and Theoretical Analysis
H. Martinez (2012)
Strains, functions and dynamics in the expanded Human Microbiome Project
Jason Lloyd-Price (2017)
A Hybridization Model for the Plasmon Response of Complex Nanostructures
E. Prodan (2003)
Structural and Functional Characterization of Malate Synthase G from Opportunistic Pathogen Pseudomonas aeruginosa.
A. C. McVey (2017)
Receptor-mediated exopolysaccharide perception controls bacterial infection
Y. Kawaharada (2015)
Surfactant-directed synthesis of silver nanorods and characteristic spectral changes occurred by their morphology evolution
Wen Zhang (2014)
Bifunctional Au-Fe3O4 nanoparticles for protein separation.
J. Bao (2007)
In situ detection of live-to-dead bacteria ratio after inactivation by means of synchronous fluorescence and PCA
R. Li (2018)
Robust classification of bacterial and viral infections via integrated host gene expression diagnostics
T. Sweeney (2016)
Kinetically controlled seed-mediated growth of narrow dispersed silver nanoparticles up to 120 nm: secondary nucleation, size focusing, and Ostwald ripening.
Ruilong L. Zong (2014)
Metagenomic Sequencing with Strain-Level Resolution Implicates Uropathogenic E. coli in Necrotizing Enterocolitis and Mortality in Preterm Infants
D. Ward (2016)
Formation of Silver Nanoparticles and Self-Assembled Two-Dimensional Ordered Superlattice
Shengtai He (2001)
Global landscape of cell envelope protein complexes in Escherichia coli
M. Babu (2018)
Silver-coated gold nanoparticles as concentrating probes and matrices for surface-assisted laser desorption/ionization mass spectrometric analysis of aminoglycosides
M. Wang (2009)
Methylation of proteins involved in translation
B. Polevoda (2007)
Cu Nanoparticles Have Different Impacts in Escherichia coli and Lactobacillus brevis than Their Microsized and Ionic Analogues.
Chitrada Kaweeteerawat (2015)
A coming era of precision diagnostics based on nano-assisted mass spectrometry
Kun Qian (2018)
The quantitative and condition-dependent Escherichia coli proteome
A. Schmidt (2016)
The role of the microbiome in cancer development and therapy
A. Bhatt (2017)
Plasmonic nanoshells enhanced laser desorption/ionization mass spectrometry for detection of serum metabolites.
X. Wei (2017)
Metabolic Fingerprinting on a Plasmonic Gold Chip for Mass Spectrometry Based in Vitro Diagnostics
Xuming Sun (2018)
Facile, one-pot synthesis, and antibacterial activity of mesoporous silica nanoparticles decorated with well-dispersed silver nanoparticles.
Y. Tian (2014)
Altered plasma proteome during an early phase of peritonitis-induced sepsis.
V. Thongboonkerd (2009)
High Performance, Multiplexed Lung Cancer Biomarker Detection on a Plasmonic Gold Chip
Bin Liu (2016)
Measuring single-cell gene expression dynamics in bacteria using fluorescence time-lapse microscopy
J. W. Young (2012)
Enzyme Mimicry for Combating Bacteria and Biofilms.
Zhaowei Chen (2018)
High-throughput metabolomic analysis predicts mode of action of uncharacterized antimicrobial compounds
M. Zampieri (2018)
Designer SiO₂@Au nanoshells towards sensitive and selective detection of small molecules in laser desorption ionization mass spectrometry.
Jinrui Gan (2015)
A novel approach for the synthesis of ultrathin silica-coated iron oxide nanocubes decorated with silver nanodots (Fe3O4/SiO2/Ag) and their superior catalytic reduction of 4-nitroaniline.
M. Abbas (2015)
Plasmon-induced hot carrier science and technology.
M. Brongersma (2015)
From Isolated Ag+ Ions to Aggregated Ag0 Nanoclusters in Silver-Exchanged Engelhard Titanosilicate (ETS-10) Molecular Sieve: Reversible Behavior
G. Agostini (2009)
Injectable Bioadhesive Hydrogels with Innate Antibacterial Properties
Michael C. Giano (2014)
Quantification of circulating Mycobacterium tuberculosis antigen peptides allows rapid diagnosis of active disease and treatment monitoring
C. Liu (2017)
Single Molecule with Dual Function on Nanogold: Biofunctionalized Construct for In Vivo Photoacoustic Imaging and SERS Biosensing
U. S. Dinish (2015)
Environmental drivers of a microbial genomic transition zone in the ocean’s interior
Daniel R. Mende (2017)
Dual-Mode Mass Spectrometric Imaging for Determination of in Vivo Stability of Nanoparticle Monolayers.
S. G. Elci (2017)
Quantifying the Sensitivity of Multipolar (Dipolar, Quadrupolar, and Octapolar) Surface Plasmon Resonances in Silver Nanoparticles: The Effect of Size, Composition, and Surface Coating.
Neus G Bastús (2016)
Optical properties of metallodielectric nanostructures calculated using the finite difference time domain method
Chris Oubre† and (2004)
A Plasmonic Mass Spectrometry Approach for Detection of Small Nutrients and Toxins
Shu Wu (2018)
Enhanced antibacterial activity through the controlled alignment of graphene oxide nanosheets
Xinglin Lu (2017)
Construction of a synthetic metabolic pathway for biosynthesis of the non-natural methionine precursor 2,4-dihydroxybutyric acid
T. Walther (2017)
Toxicity mechanisms in Escherichia coli vary for silver nanoparticles and differ from ionic silver.
A. Ivask (2014)
Sensitive and fast identification of bacteria in blood samples by immunoaffinity mass spectrometry for quick BSI diagnosis† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c5sc04919a
Y. Zhu (2016)
Fabrication and Characterization of Magnetic Microrobots for Three-Dimensional Cell Culture and Targeted Transportation
S. Kim (2013)
Rapid detection of single bacteria in unprocessed blood using Integrated Comprehensive Droplet Digital Detection
Dong-Ku Kang (2014)
Advanced Functional Nanomaterials for Theranostics.
H. Huang (2017)
Infection-targeted bactericidal nanoparticles
Li-li Li (2018)
Multifunctional Magnetic Particles for Combined Circulating Tumor Cells Isolation and Cellular Metabolism Detection.
Jiao Wu (2016)
Fabrication and nonlinear optical investigations of SiO2@Ag core-shell nanoparticles
A. Sakthisabarimoorthi (2017)
Multisubstrate-compatible ELISA procedures for rapid and high-sensitivity immunoassays
C. Dixit (2011)
Silica Nanopollens Enhance Adhesion for Long-Term Bacterial Inhibition.
H. Song (2016)
Obituary—John (Jack) Payne Woodall
Talha Khan Burki (2017)
Nucleation and Growth of Ordered Arrays of Silver Nanoparticles on Peptide Nanofibers: Hybrid Nanostructures with Antimicrobial Properties
Elena Pazos (2016)
Synergistic reaction of silver nitrate, silver nanoparticles, and methylene blue against bacteria
R. Li (2016)
This paper is referenced by
Cubic nano-silver-decorated manganese dioxide micromotors: enhanced propulsion and antibacterial performance.
W. Liu (2020)
Barcoding Amino Acids for Mutation Screening in Amyloid Beta Peptides
Phuong Huu Hoang (2019)
Urine Metabolic Fingerprints Encode Subtypes of Kidney Diseases.
J. Yang (2019)
Metabolic Fingerprinting on Synthetic Alloys for Medulloblastoma Diagnosis and Radiotherapy Evaluation.
J. Cao (2020)
FeOOH@Metal-Organic Framework Core-Satellite Nanocomposites for Serum Metabolic Fingerprints of Gynecological Cancers.
Jingjing Wan (2020)
Detection of Escherichia coli O157:H7 and Salmonella enterica serotype Typhimurium based on cell elongation induced by beta-lactam antibiotics.
M. Jia (2019)
Antibacterial mechanism of polysaccharide from Tetrastigma hemsleyanum Diels et Gilg's polysaccharides by metabolomics based on HPLC/MS.
X. Chen (2019)
High throughput analysis and quantitation of α-dicarbonyls in biofluid by plasmonic nanoshells enhanced laser desorption/ionization mass spectrometry
Qiyue Zhao (2021)
Design of Hierarchical Beads for Efficient Label-Free Cell Capture.
Shiyu Sun (2019)
A high-throughput SAMDI-mass spectrometry assay for isocitrate dehydrogenase 1.
S. Anderson (2020)
Ag-doped silicon-based nanospheres for the efficient capture and remove of iodide anions from solutions
Hualun Li (2019)
Structural characterization of phosphoethanolamine-modified lipid A from probiotic Escherichia coli strain Nissle 1917
Sung-Hyun Jo (2019)
Label-Free Detection of Transferrin Receptor by a Designed Ligand-Protein Sensor.
Wanshan Liu (2019)
Rapid Computer‐Aided Diagnosis of Stroke by Serum Metabolic Fingerprint Based Multi‐Modal Recognition
W. Xu (2020)
Bioelectronic sensor mimicking the human neuroendocrine system for the detection of hypothalamic-pituitary-adrenal axis hormones in human blood.
S. Lee (2020)
Nanoporous core@shell particles: Design, preparation, applications in bioadsorption and biocatalysis
Haiyang Su (2020)
Colorimetric determination of tumor cells via peroxidase-like activity of a cell internalizable nanozyme: Hyaluronic acid attached-silica microspheres containing accessible magnetite nanoparticles
Çiğdem Kip (2020)
A Biomimetic Plasmonic Nanoreactor for Reliable Metabolite Detection
Jiangang Liu (2020)
Diagnosis and prognosis of myocardial infarction on a plasmonic chip
W. Xu (2020)
A Multifunctional Platinum Nanoreactor for Point-of-Care Metabolic Analysis
L. Huang (2019)
In situ assembly of well-dispersed Ag nanoparticles on the surface of polylactic acid-Au@polydopamine nanofibers for antimicrobial applications.
Q. Zhang (2019)
MALDI-MS imaging of lipids in corn using a flexible ultrasonic spraying device as matrix deposition method
Xing-Li Pei (2020)
Janus particles: design, preparation, and biomedical applications
H. Su (2019)