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Cancer: Clinical Challenges And Opportunities
Published 2005 · Medicine
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Lung cancer is the leading cause of cancer death. Gene expression profiling of lung cancer may provide one method to increase our understanding of this very heterogeneous disease and potentially identify new approaches for early diagnosis, prognosis or treatment. This brief review examines some of the issues that are associated with the clinical presentation of this disease and some important questions that might be addressed using gene expression profiling experiments when applied to human lung cancer.
This paper references
Time trend and the age‐period‐cohort effect on the incidence of histologic types of lung cancer in connecticut, 1960‐1989
T. Zheng (1994)
The new World Health Organization classification of lung tumours
E. Brambilla (2001)
Laser capture microdissection and microarray expression analysis of lung adenocarcinoma reveals tobacco smoking- and prognosis-related molecular profiles.
K. Miura (2002)
Gene expression profiles in human non-small and small-cell lung cancers.
S. Difilippantonio (2003)
Lymph node mapping and curability at various levels of metastasis in resected lung cancer.
T. Naruke (1978)
Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses
Arindam Bhattacharjee (2001)
The natural history of lung cancer: a review based on rates of tumour growth.
D. Geddes (1979)
Predicting the course of Gompertzian growth
L. Norton (1976)
Molecular profiling of non-small cell lung cancer and correlation with disease-free survival.
D. Wigle (2002)
Cancer Statistics, 2003
A. Jemal (2003)
Gender and histologic type variations in smoking-related risk of lung cancer.
R. Brownson (1992)
Molecular cytogenetic analysis of non-small cell lung carcinoma by spectral karyotyping and comparative genomic hybridization.
C. Luk (2001)
Expression profiles of non-small cell lung cancers on cDNA microarrays: Identification of genes for prediction of lymph-node metastasis and sensitivity to anti-cancer drugs
T. Kikuchi (2003)
Non-small-cell lung cancer molecular signatures recapitulate lung developmental pathways.
A. Borczuk (2003)
Differential gene expression in human lung adenocarcinomas and squamous cell carcinomas.
A. McDoniels-Silvers (2002)
[Incidence of metastases and their distribution pattern in bronchial carcinoma. Autopsy findings during 5 decades (1935 to 1984)].
M. Notter (1989)
Expression profiling of primary non-small cell lung cancer for target identification
J. Heighway (2002)
Gene expression profiling of advanced lung cancer
S. Petersen (2000)
Gene-expression profiles predict survival of patients with lung adenocarcinoma
D. Beer (2002)
The effect of low‐yield cigarette smoking on lung cancer risk
E. Wynder (1988)
Patterns of lung cancer risk according to type of cigarette smoked
J. Lubin (1984)
A training-testing approach to the molecular classification of resected non-small cell lung cancer.
N. Yamagata (2003)
Identification of differentially expressed genes in pulmonary adenocarcinoma by using cDNA array
H. Wikman (2002)
Differences in lung cancer risk between men and women: examination of the evidence.
E. Zang (1996)
Different susceptibility to smoking-induced DNA damage among male and female lung cancer patients.
D. Ryberg (1994)
cDNA microarray analysis of gene expression in pathologic stage IA nonsmall cell lung carcinomas
H. Nakamura (2003)
New aspects in the staging of lung cancer. Prospective validation of the international union against cancer TNM classification
H. Bülzebruck (1992)
AJCC cancer staging handbook
F. L. Greene (2002)
Diversity of gene expression in adenocarcinoma of the lung
M. E. Garber (2001)
Significance of lymph node metastases in lung cancer.
T. Naruke (1993)
Diagnosis and treatment of lung cancer : an evidence-based guide for the practicing clinician
F. Detterbeck (2001)
Modeling tumor growth.
C. Calderón (1991)