Considerations And Challenges For Pregnancy In Polycystic Ovary Syndrome
C. Han, E. Werner
Published 2014 · Medicine
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Although the relationship of polycystic ovary syndrome (PCOS) with subfertility is well established, postconception implications of PCOS on pregnancy remain debated. Increased risk for miscarriage, gestational diabetes, hypertensive diseases of pregnancy, intrauterine growth abnormalities, perinatal mortality, and operative delivery are described in women with PCOS. Unfortunately, our understanding of definitive causal relationship to the observed associations is limited by the heterogeneity of the syndrome as well as by a paucity of large randomized controlled trials studying pregnancy in PCOS.
This paper references
Does suppressing luteinising hormone secretion reduce the miscarriage rate? Results of a randomised controlled trial
K. Clifford (1996)
Serum androgen levels in women who have recurrent miscarriages and their correlation with markers of endometrial function.
M. Okon (1998)
Pregnancy outcomes and the effect of metformin treatment in women with polycystic ovary syndrome: an overview
G. Ghazeeri (2012)
An informative protocol for the investigation of recurrent miscarriage: preliminary experience of 500 consecutive cases.
K. Clifford (1994)
Diabetes in pregnancy
P. Catalano (2000)
Prepregnancy Obesity and Fetal Death: A Study Within the Danish National Birth Cohort
E. Nohr (2005)
Role of gestational hormones in the induction of insulin resistance.
E. Ryan (1988)
A meta-analysis of pregnancy outcomes in women with polycystic ovary syndrome.
C. Boomsma (2006)
Prepregnancy BMI and the risk of gestational diabetes: a systematic review of the literature with meta-analysis.
M. R. Torloni (2009)
Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS).
B. Fauser (2004)
Effect of treatment of gestational diabetes mellitus on pregnancy outcomes.
C. Crowther (2005)
Increased prevalence of insulin resistance in women with a history of recurrent pregnancy loss.
L. Craig (2002)
Polycystic ovary syndrome, infertility, familial thrombophilia, familial hypofibrinolysis, recurrent loss of in vitro fertilized embryos, and miscarriage.
C. Glueck (2000)
Using an electrocautery strategy or recombinant follicle stimulating hormone to induce ovulation in polycystic ovary syndrome: randomised controlled trial
N. Bayram (2004)
Metformin versus placebo from first trimester to delivery in polycystic ovary syndrome: a randomized, controlled multicenter study.
E. Vanky (2010)
Polycystic ovarian syndrome and the risk of spontaneous abortion following assisted reproductive technology treatment.
J. Wang (2001)
A reappraisal of the role of polycystic ovary syndrome in recurrent miscarriage.
K. Cocksedge (2008)
Metformin versus insulin for the treatment of gestational diabetes.
J. Rowan (2008)
The effect of obesity on the outcome of infertility management in women with polycystic ovary syndrome
M. Al-Azemi (2003)
Lifestyle changes in women with polycystic ovary syndrome.
L. Moran (2011)
Effects of metformin-diet intervention before and throughout pregnancy on obstetric and neonatal outcomes in patients with polycystic ovary syndrome
C. Glueck (2013)
Reproductive impact of polycystic ovary syndrome
R. Usadi (2012)
Metformin therapy throughout pregnancy reduces the development of gestational diabetes in women with polycystic ovary syndrome.
C. Glueck (2002)
Reduced serum glycodelin and insulin-like growth factor-binding protein-1 in women with polycystic ovary syndrome during first trimester of pregnancy.
D. Jakubowicz (2004)
Detecting Insulin Resistance in Polycystic Ovary Syndrome: Purposes and Pitfalls
R. Legro (2004)
Plasminogen activator inhibitor activity: an independent risk factor for the high miscarriage rate during pregnancy in women with polycystic ovary syndrome.
C. Glueck (1999)
The origins and sequelae of abnormal neuroendocrine function in polycystic ovary syndrome.
S. K. Blank (2006)
Creasy and Resnik's Maternal-Fetal Medicine: Principles and Practice
R. K. Creasy (2013)
Management of preeclampsia and eclampsia.
J. Pritchard (1980)
Insulin-sensitising drugs (metformin, rosiglitazone, pioglitazone, D-chiro-inositol) for women with polycystic ovary syndrome, oligo amenorrhoea and subfertility.
T. Tang (2012)
Recurrent early miscarriage and polycystic ovaries.
M. Sagle (1988)
Prospective parallel randomized, double-blind, double-dummy controlled clinical trial comparing clomiphene citrate and metformin as the first-line treatment for ovulation induction in nonobese anovulatory women with polycystic ovary syndrome.
S. Palomba (2005)
Recurrent miscarriage: aetiology, management and prognosis.
T. Li (2002)
Pregnancy complications in women with polycystic ovary syndrome.
C. Boomsma (2008)
Hyperandrogenic anovulation (PCOS): a unique disorder of insulin action associated with an increased risk of non-insulin-dependent diabetes mellitus.
A. Dunaif (1995)
Predicting ongoing pregnancy following ovulation induction with recombinant FSH in women with polycystic ovary syndrome.
M. van Wely (2005)
Metformin administration versus laparoscopic ovarian diathermy in clomiphene citrate-resistant women with polycystic ovary syndrome: a prospective parallel randomized double-blind placebo-controlled trial.
S. Palomba (2004)
Risk of adverse pregnancy outcomes in women with polycystic ovary syndrome: population based cohort study
N. Roos (2011)
Polycystic ovaries and recurrent miscarriage--a reappraisal.
R. Rai (2000)
Effect of preconceptional metformin on abortion risk in polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials.
S. Palomba (2009)
Association of moderate obesity with a poor pregnancy outcome in women with polycystic ovary syndrome treated with low dose gonadotrophin
D. Hamilton‐Fairley (1992)
Men at risk: occupation and male infertility.
P. Claman (2004)
Effects of metformin on early pregnancy loss in the polycystic ovary syndrome.
D. Jakubowicz (2002)
Risk factors for pre-eclampsia at antenatal booking: systematic review of controlled studies
K. Duckitt (2005)
High prevalence of polycystic ovaries and associated clinical, endocrine, and metabolic features in women with previous gestational diabetes mellitus.
J. Holte (1998)
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