Obesity And Renal Disease
Published 2006 · Medicine
With the increasing prevalence of obesity and its impact on metabolic and cardiovascular diseases, more attention is now being focused on the relationship between obesity and renal function. It is now recognized that obesity enhances the progression of renal function deterioration to end-stage renal disease (ESRD) in subjects with known preexisting renal disease. In addition, obestiy is associated with a well-described glomerulopathy called focal segmental glomerulosclerosis (FSGS). Finally, and most important, through its close association with type 2 diabetes and hypertension, the two most important causes of ESRD in the United States (1), obesity is now felt to be a major risk factor for the development of chronic kidney disease.