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Sleep Loss And Neuronal Stress

N. Naidoo
Published 2019 · Medicine

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Sleep loss and insufficient sleep are increasingly prevalent in most societies these days. Besides the well-known effects of sleep loss such as motor vehicle and workplace accidents, studies have shown a myriad of physiological consequences including increased risk for type 2 diabetes, obesity, and cardiovascular disease. Sleep loss is known to impair cognition and affect learning and memory. More recent studies have demonstrated a link between sleep loss, neuronal stress, injury, and degeneration. Both acute and chronic sleep loss as well as sleep fragmentation have been shown to impact neurons at a molecular level and lead to injury and sometimes death. Mechanisms and pathways involved will be discussed in this chapter.
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