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Botulinum Toxin: Evidence-based Medicine Criteria In Blepharospasm And Hemifacial Spasm

W. Jost, A. Kohl
Published 2001 · Medicine

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Abstract Botulinum A toxin is recognized and approved for symptomatic treatment of hemifacial spasm and blepharospasm. The state of trials is good, although double-blind placebo-controlled studies have been carried out involving only a small number of cases. Open case control studies have been done with large patient collectives. In both indications, treatment with botulinum toxin reaches the highest EBM degree in a critical evaluation.
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