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Absorbability Of Calcium Sources: The Limited Role Of Solubility

R. Heaney, R. Recker, C. Weaver
Published 2007 · Medicine, Chemistry

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SummaryFractional absorption of seven chemically defined calcium sources was measured in normal adult women under standardized load conditions. Solubility of the sources in water at neutral pH ranged from a low of 0.04 mM to a high of 1500 mM. The relationship of solubility to absorbability was weak. In the range from 0.1 to 10 mM, within which most calcium supplement sources fall, there was no detectable effect of solubility on absorption. Data from four food sources are presented for comparison. Absorbability of food calcium was not clearly related to absorbability of the dominant chemical form in the food concerned. These findings suggest that (1) even under controlled, chemically defined conditions, solubility of a source has very little influence on its absorbability; and (2) absorbability of calcium from food sources is determined mainly by other food components.
This paper references
10.1016/S0160-3450(15)32077-8
Nutritional and pharmaceutical aspects of calcium supplementation.
C. Carr (1987)
10.1093/ajcn/50.4.830
Oxalate: effect on calcium absorbability.
R. Heaney (1989)
10.1007/BF02555147
Factors affecting absorbability of calcium from calcium salts and food
C. Pak (2007)
10.1093/ajcn/47.4.707
Calcium absorbability from spinach.
R. Heaney (1988)
Agents affecting calcification: calcium, parathyroid hormone, calcitonin, vitamin D, and other compounds
Haynes RJ (1985)
10.1007/BF02556676
Calcium absorption from a new calcium delivery system (CCM)
K. T. Smith (2007)
10.1056/NEJM198507113130202
Calcium absorption and achlorhydria.
R. Recker (1985)
Intestinal Absorption of Metal Ions and Chelates
H. Ashmead (1984)
10.1093/ajcn/51.4.656
Calcium absorption from kale.
R. Heaney (1990)
A double isotope method for measurement of intestinal absorption of calcium in man.
J. Degrazia (1965)
10.1159/000384981
Experimental Studies of Calcium Absorption in Man
F. Bronner (1962)
cium absorbability from milk products , an imitation milk , and calcium carbonate
RR Recker (1988)
10.1016/0378-5122(90)90096-O
Calcium absorption in women: relationships to calcium intake, estrogen status, and age.
R. Heaney (1989)
10.1093/ajcn/47.1.93
Calcium absorbability from milk products, an imitation milk, and calcium carbonate.
R. Recker (1988)
10.1172/JCI111254
An evaluation of the importance of gastric acid secretion in the absorption of dietary calcium.
G. Bo-Linn (1984)
10.1093/ajcn/49.2.372
Meal effects on calcium absorption.
R. Heaney (1989)
10.7326/0003-4819-108-6-905_2
Estimating true fractional calcium absorption.
R. Heaney (1988)
10.7326/0003-4819-103-4-516
Estimation of true calcium absorption.
R. Heaney (1985)
10.1056/NEJM198708273170903
Gastrointestinal absorption of calcium from milk and calcium salts.
M. Sheikh (1987)
10.1093/ajcn/47.2.262
Variability of calcium absorption.
R. Heaney (1988)
10.1002/JBMR.5650040117
A model system for assessing physicochemical factors affecting calcium absorbability from the intestinal tract
C. Pak (1989)



This paper is referenced by
Bioavailability of Nutrients and Other Bioactive Components from Dietary Supplements Factors Influencing the Measurement of Bioavailability , Taking Calcium as a Model 1
Robert Proulx Heaney (2001)
Bioavailability and Solubility of Different Calcium-Salts as a Basis for Calcium Enrichment of Beverages
Takeshi Nagai (2010)
Etude de la digestion et du confort en bouche de produits fromagers développés pour répondre aux besoins sensoriels et nutritionnels de la population senior.
L. Lorieau (2018)
Opinion on a request from the European Commission related to the 2 nd ERF carcinogenicity study on aspartame Scientific Opinion of the Panel on Food Additives and Nutrient Sources added to Food
Fernando Aguilar (2009)
10.3945/ajcn.114.090621
Bioavailability of enteric-coated microencapsulated calcium during pregnancy: a randomized crossover trial in Bangladesh.
D. E. Roth (2014)
10.1080/10408390701407266
Review of the Dietary Reference Intake for Calcium: Where Do We Go From Here?
S. Meacham (2008)
Comparison of calcium absorption from various calcium-containing products in healthy human adults: a bioavailability study
Pratibha Chaturvedi (2006)
Nutrient reference values for Australia and New Zealand: Including recommended dietary intakes
S. Capra (2006)
10.4236/FNS.2010.12009
Bioavailability and Solubility of Different Calcium-Salts as a Basis for Calcium Enrichment of Beverages
Gaby Kressel (2010)
10.3923/AJAVA.2013.613.621
Effects of Calcium Sources and Levels on Growth Performance and Calcium Bioavailability in Weaning Piglets
Hu Sen Jiang (2013)
CHELATED MINERALS Addressing Key Challenges in Mineral Supplementation
Sarah Cook (2018)
How to prevent osteoporosis
M. Bolanowski (2008)
Calcium Bioavailability of Soyfoods , Dairy Examined By
Y. Zhao ()
10.1016/J.LWT.2006.03.009
Heat stability and calcium bioavailability of calcium-fortified milk
G. Singh (2007)
Jungbunzlauer presents : The challenge of calcium fortification in beverages
()
10.1007/978-1-59259-961-5_9
Food Sources, Supplements, and Bioavailability
C. Weaver (2006)
Calcium : Which Form is Best ?
()
Effects of Calcium on Indices of Bone and Cardiovascular Health, and on Cancer
Sarah M Bristow (2014)
10.1016/B978-0-12-387784-0.00011-0
Minerals and Trace Elements
M. Kohlmeier (2014)
10.1002/jbmr.196
Solubility and bioavailability of stabilized amorphous calcium carbonate
Oren E. Meiron (2011)
16 Ingredients How to Fortify Beverages With Calcium
()
10.1590/S0482-50042009000200008
Cálcio dietético: estratégias para otimizar o consumo
Giselle A. P. Pereira (2009)
Calcium and Vitamin D in the prevention and treatment of osteoporosis: Shedding light on new developments
I. Hollis (2007)
10.1080/10408398.2018.1435503
Influence of food structure on dairy protein, lipid and calcium bioavailability: A narrative review of evidence
A. Fardet (2018)
10.1093/AJCN/83.2.310
Absorption of calcium from milks enriched with fructo-oligosaccharides, caseinophosphopeptides, tricalcium phosphate, and milk solids.
E. López-Huertas (2006)
10.3109/00365520903434117
Hypochlorhydric stomach: a risk condition for calcium malabsorption and osteoporosis?
P. Sipponen (2010)
10.2903/j.efsa.2009.1088
Calcium acetate, calcium pyruvate, calcium succinate, magnesium pyruvate magnesium succinate and potassium malate added for nutritional purposes to food supplements 1 Scientific Opinion of the Panel on Food Additives and Nutrient Sources added to Food (ANS)
F. Aguilar (2009)
Calcium Acetate Versus Calcium Carbonate as Oral Phosphate Binder: Preparation and In Vitro Assessment
N. Tavakoli (2005)
10.1016/j.foodchem.2019.125351
Evaluation of the inhibition of mercury absorption by vegetable juices using a red sea bream intestine model.
Masashi Ando (2019)
The role of calcium in peri- and postmenopausal women: 2006 position statement of the North American Menopause Society.
R. Heaney (2006)
10.1152/physrev.00015.2012
Gastric acid, calcium absorption, and their impact on bone health.
Sascha Kopic (2013)
10.1016/B978-012370544-0.50033-1
CHAPTER 31 – Nutrition and Risk for Osteoporosis
R. Heaney (2008)
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