Weight Loss Is A Major Contributor To Improved Sexual Function After Bariatric Surgery
Mireia Mora, Gloria Beatriz Aranda, Ana de Hollanda, L Flores, Manel Puig-Domingo, Josep Vidal
Published 2013 · Medicine
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BackgroundThe relative contribution of anthropometric, hormonal, and metabolic changes after bariatric surgery (BS) on sexual function (SF) in severely obese subjects is not well established.MethodsProspective observational case series study of 39 men undergoing BS. SF was assessed by means of the international index of erectile function (IIEF) before and at 1 year after surgery. At the same time points, anthropometric (body mass index, waist circumference), hormonal (testosterone, sex hormone binding globulin, estradiol, gonadotropins, inhibin B, prolactin, leptin), and metabolic parameters (insulin sensitivity, C-reactive protein, lipid profile, hemoglobin A1c, presence of hypertension or sleep apnea) were assessed.ResultsBS was associated with marked weight loss (77.18 % excess weight loss), improved IIEF score (baseline: 54.85 ± 16.59, 1 year: 61.21 ± 14.10; p < 0.01), gonadal function (testosterone: baseline 256.36 ± 120.98, 1 year: 508.01 ± 161.90; p < 0.001), and improved metabolic profile. However, on multivariate regression analysis whereas changes in body mass index (beta: −0.677, p = 0.001), and baseline IIEF score (beta: −0.397, p = 0.023), were independent predictors of the changes in the IIEF score at 1 year after surgery, changes in hormonal and metabolic factors were not. Variables in the model accounted for 66 % of the postsurgical variation in the IIEF score. Similar results were found when the different IIEF-sexual domains were evaluated, except for intercourse satisfaction for which no independent predictor was identified.ConclusionsWeight loss’s beneficial effects on SF occurring after BS are beyond the parallel improvement in gonadal and metabolic profiles.
This paper references
Sleep apnea, reproductive hormones and quality of sexual life in severely obese men.
Ahmad O. Hammoud (2011)
Insulin Resistance, Inflammation, and the Metabolic Syndrome Following Roux-en-Y Gastric Bypass Surgery in Severely Obese Subjects Published ahead of print at http://care.diabetesjournals.org on 27 April 2007. DOI: 10.2337/dc07-0189. A table elsewhere in this issue shows conventional and Système In
Rosa Morínigo (2007)
Obesity, the metabolic syndrome, and sexual dysfunction in men.
Katherine Esposito (2011)
A (2010) The effect of obesity on sperm disorders and male infertility
SS du Plessis (2010)
Sex hormones and bariatric surgery in men.
S Raghavendra Rao (2011)
A Review of the Relationships Between Extreme Obesity, Quality of Life, and Sexual Function
David B Sarwer (2012)
Sexual Function in Men Older Than 50 Years of Age: Results from the Health Professionals Follow-up Study
Constance G Bacon (2003)
American Association of Clinical Endocrinologists, The Obesity Society, and American Society for Metabolic & Bariatric Surgery Medical Guidelines for Clinical Practice for the perioperative nutritional, metabolic, and nonsurgical support of the bariatric surgery patient.
Jeffrey I. Mechanick (2008)
Update: Hypogonadotropic hypogonadism in type 2 diabetes and obesity.
Paresh Dandona (2011)
Inhibin B in Men with Severe Obesity and After Weight Reduction Following Gastroplasty
Hadas Globerman (2005)
Erectile dysfunction and hormonal imbalance in morbidly obese male is reversed after gastric bypass surgery: a prospective randomized controlled trial.
Leonardo Oliveira Reis (2010)
The importance of diagnostic criteria in the association between the metabolic syndrome and cardiovascular disease in obese subjects
Josep Vidal (2005)
Effects of bariatric surgery on urinary and sexual function.
Weranja K B Ranasinghe (2011)
A critical evaluation of simple methods for the estimation of free testosterone in serum.
A. Vermeulen (1999)
Effect of bariatric surgery on cardiovascular risk profile.
H M Heneghan (2011)
Effect of lifestyle changes on erectile dysfunction in obese men: a randomized controlled trial.
Katherine Esposito (2004)
Does weight loss improve semen quality and reproductive hormones? results from a cohort of severely obese men
Linn Berger Håkonsen (2011)
Validated questionnaires for assessing sexual dysfunction and BPH/LUTS: solidifying the common pathophysiologic link
Raymond C. Rosen (2008)
Short-term Effects of Sleeve Gastrectomy on Type 2 Diabetes Mellitus in Severely Obese Subjects
Josep Vidal (2007)
Clinical practice guidelines for the perioperative nutritional, metabolic, and nonsurgical support of the bariatric surgery patient--2013 update: cosponsored by American Association of Clinical Endocrinologists, The Obesity Society, and American Society for Metabolic & Bariatric Surgery.
Jeffrey I. Mechanick (2013)
The international index of erectile function (IIEF): a multidimensional scale for assessment of erectile dysfunction.
Raymond C. Rosen (1997)
Prevalence of hypogonadism in males aged at least 45 years: the HIM study
Thomas M. Mulligan (2006)
The effect of obesity on sperm disorders and male infertility
Stefan S. du Plessis (2010)
Inflammatory biomarkers and risks of myocardial infarction, stroke, diabetes, and total mortality: implications for longevity.
Paul M. Ridker (2007)
Sexual dysfunction is common in the morbidly obese male and improves after gastric bypass surgery.
Ramsey M. Dallal (2008)
Impaired quality of life and sexual function in overweight and obese men: the European Male Ageing Study.
Thang Sieu Han (2011)
Bariatric Surgery Does not Interfere With Sperm Quality—A Preliminary Long-Term Study
Leonardo Oliveira Reis (2012)
Relation between psychosocial risk factors and incident erectile dysfunction: prospective results from the Massachusetts Male Aging Study.
Andre Araujo (2000)
Erectile dysfunction and coronary risk factors: prospective results from the Massachusetts male aging study.
Henry A. Feldman (2000)
Effect of Roux-en-Y gastric bypass surgery on the sex steroids and quality of life in obese men.
Ahmad O. Hammoud (2009)
This paper is referenced by
Chapter 19 – Testicular Disorders
Alvin M. Matsumoto (2012)
Effects of Lifestyle Changes and Testosterone Therapy on Erectile Function
Abdulmaged M Traish (2016)
Does Metabolic Syndrome Impair Sexual Functioning in Adults With Overweight and Obesity?
Saeideh Botlani Esfahani (2019)
Does sleeve gastrectomy improve the gait parameters of obese patients?
Lionel Rebibo (2016)
Cross-sectional study of male sexual function in bariatric patients
Michał R. Janik (2016)
Erectile dysfunction in cardiovascular risk population
Otto Ettala (2015)
Gender disparities in weight loss surgery
Sherif G. Aly (2020)
Evalution of Weight Control and Nutrition Education in Erectile Dysfunction Treatment
Ersan Arda (2019)
Early Effect of Bariatric Surgery on Urogenital Function in Morbidly Obese Men.
M. Aleid (2017)
Metabolic and Endocrine Consequences of Bariatric Surgery
Isabel Cornejo-Pareja (2019)
Effect of Bariatric Surgery on Male Sexual Function: A Meta-Analysis and Systematic Review
Jiangnan Xu (2019)
Sexual functioning of men and women with severe obesity before bariatric surgery.
Kristine J. Steffen (2017)
Sexual functioning in men who underwent bariatric surgery: far beyond sex hormones.
Leonardo Oliveira Reis (2015)
Impact of Bariatric Surgery on Male Sex Hormones and Sperm Quality: a Systematic Review and Meta-Analysis
Yung Lee (2018)
Effect of Body Weight on Sexual Function in Men and Women
Jenna Bates (2019)
Effect of Bariatric Surgery on the Circulating Level of Adiponectin, Chemerin, Plasminogen Activator Inhibitor-1, Leptin, Resistin, and Visfatin: A Systematic Review and Meta-Analysis.
Moein Askarpour (2020)
Bariatric Surgery Improves Sexual Function in Obese Patients.
David Goitein (2015)
The relationships between bariatric surgery and sexual function: current evidence based medicine
Dehong Cao (2020)
Sex Hormone-Binding Globulin and the Metabolic Syndrome
Geoffrey L. Hammond (2017)
The Effects of Laparoscopic Adjustable Gastric Band Procedure on the Sexual Functioning
Gaye Çelikcan (2019)
Fertility and Testosterone Improvement in Male Patients After Bariatric Surgery
Michaela Luconi (2015)
Effects of bariatric surgery on male lower urinary tract symptoms and sexual function.
Asnat Groutz (2017)
Mechanisms for T 2 DM Remission After BS
Isabel Cornejo-Pareja (2019)
Change in Sexual Dysfunction Following Bariatric Surgery
Laura Wingfield (2015)
Obesity and Reproduction.
Neal Mahutte (2018)
Obesity, Male Reproductive Function and Bariatric Surgery
Angelo Di Vincenzo (2018)
Male Obesity-related Secondary Hypogonadism – Pathophysiology, Clinical Implications and Management
Cornelius J Fernandez (2019)
Investigating the Effects of Lifestyle Changes on Sexual Function of Patients Undergoing Hemodialysis Procedures
Parvin Kazemi (2016)
Decreased visceral fat area correlates with improved total testosterone levels after Roux-en-Y gastric bypass in obese Chinese males with type 2 diabetes: a 12-month follow-up.
Fangyuan Liu (2018)
Effect of testosterone therapy combined with a very low caloric diet in obese men: a randomised controlled trial
Ng Tang Fui (2017)
Sexual functioning and sex hormones in men who underwent bariatric surgery.
David B Sarwer (2015)
Obesity and late-onset hypogonadism
G. Corona (2015)See more