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Safe Cholecystectomy Multi-society Practice Guideline And State-of-the-art Consensus Conference On Prevention Of Bile Duct Injury During Cholecystectomy

L. Michael Brunt, D. Deziel, D. Telem, S. Strasberg, R. Aggarwal, H. Asbun, J. Bonjer, Marian McDonald, A. Alseidi, M. Ujiki, T. Riall, C. Hammill, C. Moulton, P. Pucher, R. Parks, M. T. Ansari, Saxon Connor, Rebecca C. Dirks, B. Anderson, Maria S. Altieri, L. Tsamalaidze, D. Stefanidis, Domenech Chantel Luigi Ryan Eugene Marie Chris Shanley Scot Asbun den Baaker Boni Campagna Ceppa Crandall Davi, Domenech Asbun, Chantel den Baaker, L. Boni, Ryan Campagna, E. Ceppa, M. Crandall, C. Davis, Shanley B. Deal, Scott Dojels, Ismael Domiguez-Rosado, Leonie van Gastel, Justin Gerard, D. Hashimoto, E. Harrison, S. Holden, R. Ignacio, O. Imventarz, R. Jeyarajah, Mackenzie Landin, C. Lawrence, Marc G. Mesleh, Sara Monafred, A. Paganini, B. Fernando Santos, S. Sikora, Tim Schaffner, Nate Stoikes, Bailey Su, M. Thomas, Ben Veenstra, Waala Abdelmoaty, E. Zwart
Published 2020 · Medicine

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Background Bile duct injury (BDI) is the most common serious complication of laparoscopic cholecystectomy. To address this problem, a multi-society consensus conference was held to develop evidenced-based recommendations for safe cholecystectomy and prevention of BDI. Methods Literature reviews were conducted for 18 key questions across six broad topics around cholecystectomy directed by a steering group and subject experts from five surgical societies (SAGES, AHPBA IHPBA, SSAT, and EAES). Evidence-based recommendations were formulated using the GRADE methodology. When evidence-based recommendations could not be made, expert opinion was documented. A number of recommendations for future research were also documented. Recommendations were presented at a consensus meeting in October 2018 and were voted on by an international panel of 25 experts with greater than 80% agreement considered consensus. Results Consensus was reached on 17 of 18 questions by the Guideline Development Group (GDG) and expert panel with high concordance from audience participation. Most recommendations were conditional due to low certainty of evidence. Strong recommendations were made for (1) use of intraoperative biliary imaging for uncertainty of anatomy or suspicion of biliary injury; and (2) referral of patients with confirmed or suspected BDI to an experienced surgeon/multispecialty hepatobiliary team. Conclusion These consensus recommendations should provide guidance to surgeons, training programs, hospitals, and professional societies for strategies that have the potential to reduce BDIs and positively impact patient outcomes. Development of clinical and educational research initiatives based on these recommendations may drive further improvement in the quality of surgical care for patients undergoing cholecystectomy.
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