Online citations, reference lists, and bibliographies.
← Back to Search

Scaffolds And Cells For Tissue Regeneration: Different Scaffold Pore Sizes—different Cell Effects

Ieva Bružauskaitė, D. Bironaitė, E. Bagdonas, E. Bernotiene
Published 2015 · Chemistry, Medicine

Save to my Library
Download PDF
Analyze on Scholarcy
Share
During the last decade biomaterial sciences and tissue engineering have become new scientific fields supplying rising demand of regenerative therapy. Tissue engineering requires consolidation of a broad knowledge of cell biology and modern biotechnology investigating biocompatibility of materials and their application for the reconstruction of damaged organs and tissues. Stem cell-based tissue regeneration started from the direct cell transplantation into damaged tissues or blood vessels. However, it is difficult to track transplanted cells and keep them in one particular place of diseased organ. Recently, new technologies such as cultivation of stem cell on the scaffolds and subsequently their implantation into injured tissue have been extensively developed. Successful tissue regeneration requires scaffolds with particular mechanical stability or biodegradability, appropriate size, surface roughness and porosity to provide a suitable microenvironment for the sufficient cell–cell interaction, cell migration, proliferation and differentiation. Further functioning of implanted cells highly depends on the scaffold pore sizes that play an essential role in nutrient and oxygen diffusion and waste removal. In addition, pore sizes strongly influence cell adhesion, cell–cell interaction and cell transmigration across the membrane depending on the various purposes of tissue regeneration. Therefore, this review will highlight contemporary tendencies in application of non-degradable scaffolds and stem cells in regenerative medicine with a particular focus on the pore sizes significantly affecting final recover of diseased organs.
This paper references
10.1007/s10856-013-4934-1
A novel porous scaffold fabrication technique for epithelial and endothelial tissue engineering
K. McHugh (2013)
10.1016/J.ADDR.2007.04.021
Functional electrospun nanofibrous scaffolds for biomedical applications.
D. Liang (2007)
10.1016/J.BIOMATERIALS.2005.02.002
Porosity of 3D biomaterial scaffolds and osteogenesis.
V. Karageorgiou (2005)
10.1021/JA060573X
Self-assembly of peptide-amphiphile nanofibers: the roles of hydrogen bonding and amphiphilic packing.
S. E. Paramonov (2006)
10.1002/bit.23027
Marrow‐Derived stem cell motility in 3D synthetic scaffold is governed by geometry along with adhesivity and stiffness
S. Peyton (2011)
Induced pluripotent stem
II Slukvin (2007)
10.1002/(SICI)1097-4636(199707)36:1<17::AID-JBM3>3.0.CO;2-O
Bone formation by three-dimensional stromal osteoblast culture in biodegradable polymer scaffolds.
S. L. Ishaug (1997)
10.1002/jbm.a.32798
Epidermal and dermal integration into sphere-templated porous poly(2-hydroxyethyl methacrylate) implants in mice.
Y. Fukano (2010)
culating mesenchymal stem cells
CA Roufosse (2004)
10.1006/JMCC.2001.1367
Cardiomyocyte grafting for cardiac repair: graft cell death and anti-death strategies.
M. Zhang (2001)
10.1186/scrt501
Synovial fluid and synovial membrane mesenchymal stem cells: latest discoveries and therapeutic perspectives
Eduardo Branco de Sousa (2014)
10.1634/stemcells.2006-0814
A Novel Culture Technique for Human Embryonic Stem Cells Using Porous Membranes
S. Kim (2007)
10.1016/j.biomaterials.2008.09.017
In vitro cell alignment obtained with a Schwann cell enriched microstructured nerve guide with longitudinal guidance channels.
A. Bozkurt (2009)
10.1016/S1369-7021(11)70058-X
Biomaterials & scaffolds for tissue engineering
F. Obrien (2011)
10.1016/j.biomaterials.2010.10.056
Cell infiltration and growth in a low density, uncompressed three-dimensional electrospun nanofibrous scaffold.
B. Blakeney (2011)
10.1016/j.cell.2006.07.024
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
Kazutoshi Takahashi (2006)
10.1096/fj.09-145177
Comparison of contractile behavior of native murine ventricular tissue and cardiomyocytes derived from embryonic or induced pluripotent stem cells
Jiao-ya Xi (2010)
10.4103/1673-5374.133160
Neural stem cell transplantation in a double-layer collagen membrane with unequal pore sizes for spinal cord injury repair
N. Yuan (2014)
10.1126/science.1151526
Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells
J. Yu (2007)
10.1016/j.biomaterials.2009.09.063
The effect of mean pore size on cell attachment, proliferation and migration in collagen-glycosaminoglycan scaffolds for bone tissue engineering.
C. Murphy (2010)
10.1023/B:ABME.0000017544.36001.8e
Polymeric Scaffolds for Bone Tissue Engineering
X. Liu (2004)
10.1046/j.1365-2141.2000.01986.x
Mesenchymal progenitor cells in human umbilical cord blood
A. Erices (2000)
10.1016/0142-9612(96)85758-9
Role of material surfaces in regulating bone and cartilage cell response.
B. Boyan (1996)
10.1002/stem.1066
Concise Review: Immune Recognition of Induced Pluripotent Stem Cells
A. Boyd (2012)
10.1016/J.BIOMATERIALS.2003.10.086
Microcellular polyHIPE polymer supports osteoblast growth and bone formation in vitro.
G. Akay (2004)
10.1163/1568562042459733
Characterization of neural stem cells on electrospun poly(L-lactic acid) nanofibrous scaffold
F. Yang (2004)
Migration of polarized epithelial cells through permeable membrane substrates of defined pore size.
S. Tucker (1992)
Biomaterials with tightly controlled pore size that promote vascular in-growth
A. Marshall (2004)
Mesenchymal stem cells from primary breast cancer tissue promote cancer proliferation and enhance mammosphere formation partially via EGF/EGFR/Akt
YanXL (2012)
Electrospun scaffolds for stem cell
SH Lim (2009)
10.1002/JBM.A.30232
Synthetic scaffold morphology controls human dermal connective tissue formation.
H. Wang (2005)
Cytological demonstration of the clonal
AJ Becker (1963)
10.1073/pnas.1006442107
Proangiogenic scaffolds as functional templates for cardiac tissue engineering
Lauran R. Madden (2010)
10.1002/JBM.10318
Fabrication and surface modification of macroporous poly(L-lactic acid) and poly(L-lactic-co-glycolic acid) (70/30) cell scaffolds for human skin fibroblast cell culture.
J. Yang (2002)
10.1016/J.BIOMATERIALS.2003.12.019
Novel porous aortic elastin and collagen scaffolds for tissue engineering.
Qijin Lu (2004)
10.1016/0076-6879(82)82080-6
[23] Cell-collagen interactions: Overview
F. Grinnell (1982)
10.5772/54372
De-Differentiation of Somatic Cells to a Pluripotent State
C. Wenceslau (2013)
10.1002/jbm.a.32834
Design of three-dimensional biomimetic scaffolds.
S. Owen (2010)
10.1126/SCIENCE.284.5411.143
Multilineage potential of adult human mesenchymal stem cells.
M. Pittenger (1999)
10.1290/1071-2690(2000)036<0476:DGFIBS>2.0.CO;2
Diffusable growth factors induce bladder smooth muscle differentiation
Wenhui Liu (2000)
10.1088/1748-6041/3/3/034002
Electrospun nanofiber scaffolds: engineering soft tissues.
S. Kumbar (2008)
10.1038/40687
Erratum: Integrin–ligand binding properties govern cell migration speed through cell–substratum adhesiveness
S. Palecek (1997)
10.1166/JBN.2005.013
Surface Engineering of Nano-Fibrous Poly(L-Lactic Acid) Scaffolds via Self-Assembly Technique for Bone Tissue Engineering
X. Liu (2005)
10.1186/1749-799X-3-17
Fibrin and poly(lactic-co-glycolic acid) hybrid scaffold promotes early chondrogenesis of articular chondrocytes: an in vitro study
M. Sha'ban (2008)
10.1016/S8756-3282(99)00192-1
Effect of surface roughness on proliferation and alkaline phosphatase expression of rat calvarial cells cultured on polystyrene.
K. Hatano (1999)
10.1002/(SICI)1097-4636(199811)42:2<245::AID-JBM9>3.0.CO;2-P
Surface topography can interfere with epithelial tissue migration.
J. Fitton (1998)
10.1016/J.BIOMATERIALS.2004.03.015
The influence of microchannels on neurite growth and architecture.
M. Mahoney (2005)
10.1016/J.BIOMATERIALS.2006.06.013
Nano-fibrous scaffolding promotes osteoblast differentiation and biomineralization.
K. Woo (2007)
10.1016/0002-9149(91)90255-J
Ventricular enlargement and remodeling following acute myocardial infarction: mechanisms and management.
E. Braunwald (1991)
Scaffold mean pore
A 45100–101 Matsiko (2015)
10.1002/1097-4636(200105)55:2<141::AID-JBM1000>3.0.CO;2-J
Biodegradable polymeric scaffolds for musculoskeletal tissue engineering.
C. Agrawal (2001)
10.1038/197452A0
Cytological Demonstration of the Clonal Nature of Spleen Colonies Derived from Transplanted Mouse Marrow Cells
A. Becker (1963)
10.1083/jcb.201210152
Physical limits of cell migration: Control by ECM space and nuclear deformation and tuning by proteolysis and traction force
K. Wolf (2013)
10.3233/THC-2007-15102
The effect of pore size on permeability and cell attachment in collagen scaffolds for tissue engineering.
F. Obrien (2007)
The effect of pore size on permeability and cell attachment in collagen scaffolds for tissue
FJ O’Brien (2007)
10.1111/j.1365-4632.2008.03380.x
Human mesenchymal stem cells may be involved in keloid pathogenesis
K. Akino (2008)
10.2147/IJN.S73096
Thickness-controllable electrospun fibers promote tubular structure formation by endothelial progenitor cells
Jong Kyu Hong (2015)
10.1089/107632701300062859
Multilineage cells from human adipose tissue: implications for cell-based therapies.
P. Zuk (2001)
10.1016/J.CARDIORES.2004.05.012
Genes, stem cells and biological pacemakers.
M. Rosen (2004)
10.4049/jimmunol.179.3.1595
Adult Human Fibroblasts Are Potent Immunoregulatory Cells and Functionally Equivalent to Mesenchymal Stem Cells1
M. Haniffa (2007)
10.1371/journal.pone.0111566
The Effect of 3D Nanofibrous Scaffolds on the Chondrogenesis of Induced Pluripotent Stem Cells and Their Application in Restoration of Cartilage Defects
J. Liu (2014)
10.2217/nnm.14.212
Nanotechnology in bladder cancer: current state of development and clinical practice.
B. Tomlinson (2015)
10.1016/0267-6605(92)90098-E
Tissue regeneration by use of collagen-glycosaminoglycan copolymers.
I. Yannas (1992)
A novel porous
SL Tao (2013)
10.1038/nbt1274
Isolation of amniotic stem cell lines with potential for therapy
P. Coppi (2007)
10.1002/(SICI)1097-4636(199824)43:4<422::AID-JBM9>3.0.CO;2-1
Polymer concepts in tissue engineering.
S. Peter (1998)
10.1006/JMCC.2001.1491
Survival and development of neonatal rat cardiomyocytes transplanted into adult myocardium.
J. Mueller-Ehmsen (2002)
using porous membranes
MY Kim (2014)
10.1126/SCIENCE.284.5413.489
Functional arteries grown in vitro.
L. Niklason (1999)
10.1371/journal.pone.0014297
c-kitpos GATA-4 High Rat Cardiac Stem Cells Foster Adult Cardiomyocyte Survival through IGF-1 Paracrine Signalling
N. Kawaguchi (2010)
10.1177/0022034509340867
Mesenchymal Stem Cells Derived from Dental Tissues vs. Those from Other Sources: Their Biology and Role in Regenerative Medicine
G. T. Huang (2009)
Functional electrospun
BS Hsiao (2007)
10.1002/wnan.26
Nanostructured polymer scaffolds for tissue engineering and regenerative medicine.
I. O. Smith (2009)
10.1016/0300-5712(78)90023-4
Implantation of porous polymethylmethacrylate resin for tooth and bone replacement
B. Roberts (1978)
10.1016/J.BIOCEL.2003.10.007
Circulating mesenchymal stem cells.
C. Roufosse (2004)
10.1016/j.addr.2009.07.011
Electrospun scaffolds for stem cell engineering.
S. Lim (2009)
10.1161/01.RES.0000196867.12470.84
Small-diameter artificial arteries engineered in vitro.
B. Isenberg (2006)
Polymeric scaffolds for bone tissue
X 1016j.addr.2009.07.011 Liu (2004)
Cell-collagen interactions: overview.
F. Grinnell (1982)
Survival and devel
TI Long (2002)
10.1016/j.actbio.2011.04.006
Increasing capillary diameter and the incorporation of gelatin enhance axon outgrowth in alginate-based anisotropic hydrogels.
K. Pawar (2011)
10.1186/2055-7124-18-7
Stimulated migration and penetration of vascular endothelial cells into poly (L-lactic acid) scaffolds under flow conditions
min-ah koo (2014)
10.1016/j.ejps.2009.03.010
Delivery of bioactive macromolecules from microporous polymer matrices: Release and activity profiles of lysozyme, collagenase and catalase.
Y. Wang (2009)
10.1016/j.actbio.2010.02.030
The effects of pore architecture in silk fibroin scaffolds on the growth and differentiation of mesenchymal stem cells expressing BMP7.
Y. Zhang (2010)
10.1002/jbm.a.34646
The effect of porosity of a biphasic ceramic scaffold on human skeletal stem cell growth and differentiation in vivo.
A. Aarvold (2013)
10.1089/ten.TEA.2013.0545
Scaffold mean pore size influences mesenchymal stem cell chondrogenic differentiation and matrix deposition.
A. Matsiko (2015)
10.1063/1.2372694
Drawing suspended polymer micro-/nanofibers using glass micropipettes
Amrinder S. Nain (2006)
10.3760/CMA.J.ISSN.0376-2491.2011.10.013
[Growth and migration of umbilical cord mesenchymal stem cells on polycarbonate membrane with different pore sizes].
Dong-Jie Li (2011)
Pore size variable type I
YL Polym Ed 151483–1497 Yang (2010)
10.1021/NL0700346
Aligned Arrays of Biodegradable Poly(ε-caprolactone) Nanowires and Nanofibers by Template Synthesis
S. Tao (2007)
10.1002/JBM.10167
Electrospun nanofibrous structure: a novel scaffold for tissue engineering.
W. Li (2002)
10.1186/1465-9921-14-9
Mesenchymal stem cells promote alveolar epithelial cell wound repair in vitro through distinct migratory and paracrine mechanisms
Khondoker M Akram (2013)
10.1002/JBM.820040309
Potential of ceramic materials as permanently implantable skeletal prostheses.
S. Hulbert (1970)
10.1016/j.biomaterials.2011.01.049
The performance of laminin-containing cryogel scaffolds in neural tissue regeneration.
M. Jurga (2011)
10.1038/385537A0
Integrin-ligand binding properties govern cell migration speed through cell-substratum adhesiveness
S. Palecek (1997)
10.1126/SCIENCE.1553558
Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system.
B. Reynolds (1992)
The effect of mean
CM 1006jmcc.2001.1491 Murphy (2010)
10.1089/107632701753213183
Effect of pore size and void fraction on cellular adhesion, proliferation, and matrix deposition.
J. Zeltinger (2001)
Biological response of chondrocytes cultured in three-dimensional nanofibrous poly(epsilon-caprolactone) scaffolds.
W. Li (2003)
10.1007/s10549-011-1577-0
Mesenchymal stem cells from primary breast cancer tissue promote cancer proliferation and enhance mammosphere formation partially via EGF/EGFR/Akt pathway
X. Yan (2011)
10.1126/SCIENCE.1064829
Taking Cell-Matrix Adhesions to the Third Dimension
E. Cukierman (2001)
Migration of polarized epithelial cells through permeable membrane substrates of defined pore size.
Tucker Sp (1992)
10.1016/J.BIOMATERIALS.2005.06.035
Neurite bridging across micropatterned grooves.
J. Goldner (2006)
Aligned arrays of biodegradable poly(epsilon-caprolactone) nanowires and nanofibers by template synthesis.
S. Tao (2007)
10.1182/BLOOD.V79.11.2821.BLOODJOURNAL79112821
Direct contact between human primitive hematopoietic progenitors and bone marrow stroma is not required for long-term in vitro hematopoiesis.
C. Verfaillie (1992)
10.1002/jbm.a.32309
The behavior of mesenchymal stem cells on micropatterned PLLA membranes.
I-Chi Lee (2009)
10.1002/JBM.A.10098
Nano-fibrous scaffolding architecture selectively enhances protein adsorption contributing to cell attachment.
K. Woo (2003)
10.1016/j.jpedsurg.2011.10.013
Regenerative medicine strategies.
A. Atala (2012)
10.1038/nbt1374
Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts
M. Nakagawa (2008)
10.1007/BF02634136
An in vitro model for cell-cell interactions
K. Saunders (2007)
10.1016/J.BIOMATERIALS.2003.11.034
Response of MG63 osteoblast-like cells onto polycarbonate membrane surfaces with different micropore sizes.
S. Lee (2004)
10.5772/21983
Cell Responses to Surface and Architecture of Tissue Engineering Scaffolds
Hsin-I Chang (2011)
Biomaterials & scaffolds for tissue engineering. Mater Today 14:88–95
FJ O’Brien (2011)
Induction of pluripotent stem
K Takahashi (2006)
10.1016/j.biomaterials.2010.03.039
Pore size variable type I collagen gels and their interaction with glioma cells.
Ya-li Yang (2010)
Osteogenic cells on bio-inspired materials for bone tissue engineering.
B. Vagaská (2010)
10.1529/biophysj.107.122598
Microarchitecture of three-dimensional scaffolds influences cell migration behavior via junction interactions.
B. Harley (2008)
10.1007/978-3-211-72958-8_15
Nerve regeneration using tubular scaffolds from biodegradable polyurethane.
T. Hausner (2007)
10.1002/jbm.a.31816
Effect of scaffold architecture and pore size on smooth muscle cell growth.
M. Lee (2008)
10.1016/j.biomaterials.2014.07.011
Engineering vascular tissue with functional smooth muscle cells derived from human iPS cells and nanofibrous scaffolds.
Yongyu Wang (2014)
10.1006/DBIO.1999.9565
A new look at the origin, function, and "stem-cell" status of muscle satellite cells.
P. Seale (2000)
10.1016/J.BBAMCR.2004.04.007
Focal adhesion regulation of cell behavior.
Michele A. Wozniak (2004)
Integrin Dynamics and Matrix Assembly
R. Pankov (2000)
10.1016/J.MEMSCI.2013.11.034
Microfabrication of High-Resolution Porous Membranes for Cell Culture.
M. Kim (2014)
10.1016/J.BIOMATERIALS.2007.07.006
Characterisation of the macroporosity of polycaprolactone-based biocomposites and release kinetics for drug delivery.
Y. Wang (2007)
10.1016/S0276-1092(08)70029-4
Replacement of the Knee Meniscus by a Porous Polymer Implant: A Study in DogsTienen TG, Heijkants RGJC, de Groot JH, et al (Univ Med Ctr Nijmegen, the Netherlands; State Univ of Groningen, the Netherlands) Am J Sports Med 34:64–71, 2006§
B. Morrey (2007)
10.1002/JBM.A.10101
Biological response of chondrocytes cultured in three-dimensional nanofibrous poly(ϵ-caprolactone) scaffolds†
W. Li (2003)



This paper is referenced by
10.4103/jasmr.jasmr_18_19
The odontogenic performance of human dental pulp stem cell in 3-dimensional chitosan and nano-bioactive glass-based scaffold material with different pores size
Reham A. A. Morsy (2019)
10.3390/polym8050200
Thermogel-Coated Poly(ε-Caprolactone) Composite Scaffold for Enhanced Cartilage Tissue Engineering
Shao-Jie Wang (2016)
10.1007/S10856-019-6343-6
Injectable hydrogel based on dialdehyde galactomannan and N-succinyl chitosan: a suitable platform for cell culture.
Everton Lucas de Lima (2020)
10.1088/1748-605X/ab99d5
Constructed microbubble porous scaffolds of polyvinyl alcohol for subchondral bone formation for osteoarthritis surgery.
Tanchanok Parivatphun (2020)
10.15171/bi.2020.06
Propagation of limbal stem cells on polycaprolactone and polycaprolactone/gelatin fibrous scaffolds and transplantation in animal model
Fatemeh Sanie-Jahromi (2020)
10.1080/09205063.2019.1678796
5-Azacytidine incorporated polycaprolactone-gelatin nanoscaffold as a potential material for cardiomyocyte differentiation
K. Rachel (2019)
10.1002/jcb.28980
Synthesis and evaluation of injectable thermosensitive penta‐block copolymer hydrogel (PNIPAAm‐PCL‐PEG‐PCL‐PNIPAAm) and star‐shaped poly(CL─CO─LA)‐b‐PEG for wound healing applications
F. Oroojalian (2019)
10.2217/rme-2018-0044
Stem and progenitor cell microenvironment for bone regeneration and repair.
C. Lee (2019)
10.1016/j.msec.2020.111189
3D printing and characterization of human nasoseptal chondrocytes laden dual crosslinked oxidized alginate-gelatin hydrogels for cartilage repair approaches.
S. Schwarz (2020)
10.1007/978-3-319-33037-2_137-1
Biologics: Inherent Challenges
Charles M. C. Lee (2020)
10.1016/j.ijbiomac.2019.07.155
Natural composite dressings based on collagen, gelatin and plant bioactive compounds for wound healing: A review.
Alexandra Gaspar-Pintiliescu (2019)
10.18063/ijb.v5i1.163
Near-field electrospinning of a polymer/bioactive glass composite to fabricate 3D biomimetic structures
K. Kolan (2019)
10.1007/s12221-020-9418-6
Crosslinked Ionic Alginate and Cellulose-based Hydrogels for Photoresponsive Drug Release Systems
Fang Zhou (2020)
10.1016/j.jma.2020.05.006
Pore characterization of PM Mg–0.6Ca alloy and its degradation behavior under physiological conditions
Eshwara Phani Shubhakar Nidadavolu (2020)
10.1016/j.ceramint.2020.01.050
Synthesis and characterization of magnesium-lanthanum dual doped bioactive glasses
Hossein Jodati (2020)
10.1186/s40824-019-0172-z
Increased pore size of scaffolds improves coating efficiency with sulfated hyaluronan and mineralization capacity of osteoblasts
Jan Krieghoff (2019)
10.1016/j.matdes.2019.108424
A novel auxetic structure based bone screw design: Tensile mechanical characterization and pullout fixation strength evaluation
Y. Yao (2020)
10.1016/J.APSUSC.2017.08.005
Fabrication of Polycaprolactone Electrospun Fibers with Different Hierarchical Structures Mimicking Collagen Fibrils for Tissue Engineering Scaffolds
L. Jiang (2018)
10.1115/1.4043036
Computational Design and Optimization of Nerve Guidance Conduits for Improved Mechanical Properties and Permeability.
S. Zhang (2019)
10.1080/09205063.2020.1815278
Fluidic embedding of additional macroporosity in alginate-gelatin composite structure for biomimetic application
Arindam Banerjee (2020)
10.1038/s41598-019-48429-1
Osteostimulatory effect of biocomposite scaffold containing phytomolecule diosmin by Integrin/FAK/ERK signaling pathway in mouse mesenchymal stem cells
S. Chandran (2019)
10.3233/ch-199206
The Effect of stiffness variation of electrospun fiber meshes of multiblock copolymers on the osteogenic differentiation of human mesenchymal stem cells.
X. Sun (2019)
10.1007/s40883-020-00166-y
Recent Advancements and Associated Challenges of Scaffold Fabrication Techniques in Tissue Engineering Applications
Arun Koyyada (2020)
10.1007/s40883-020-00165-z
Platelet Concentrates as Biomaterials in Tissue Engineering: a Review
S. Jasmine (2020)
10.1155/2019/6279721
Bone Tissue Regeneration in the Oral and Maxillofacial Region: A Review on the Application of Stem Cells and New Strategies to Improve Vascularization
Vivian Wu (2019)
10.1039/C7PY01375B
Tailored emulsion-templated porous polymer scaffolds for iPSC-derived human neural precursor cell culture
Ashley R Murphy (2017)
Matériaux poreux à base de polyuréthane pour l’ingénierie tissulaire
G. Lutzweiler (2019)
10.1016/j.tice.2018.09.003
Development of a demineralized and decellularized human epiphyseal bone scaffold for tissue engineering: A histological study.
Elham Abedin (2018)
10.3390/pharmaceutics11120678
Bi-Layered Polymer Carriers with Surface Modification by Electrospinning for Potential Wound Care Applications
Mirja Palo (2019)
10.1002/masy.202000046
Assessment of Biocompatibility and Vascular Effects of Polymeric Materials Using Chick Chorioallantoic Membrane, an Alternative Method
Lays Fernanda Nunes Dourado (2020)
10.1088/1748-605x/abac4c
Effective production of multifunctional magnetic-sensitive biomaterial by an extrusion-based additive manufacturing technique.
A. F. Rodrigues (2020)
10.1016/J.CERAMINT.2019.06.048
Easy manufacturing of 3D ceramic scaffolds by the foam replica technique combined with sol-gel or ceramic slurry
C. Navalón (2019)
See more
Semantic Scholar Logo Some data provided by SemanticScholar