Online citations, reference lists, and bibliographies.
← Back to Search

Optimization Of Bioactive Compounds Extraction Assisted By Microwave Parameters From Kappaphycus Alvarezii Using RSM And ANFIS Modeling

Suraj Baskararaj, Panneerselvam Theivendren, P. Palanisamy, Suthendran Kannan, P. Pavadai, S. Arunachalam, Murugesan Sankaranarayanan, Uma Priya Mohan, Lokeshkumar Ramasamy, Selvaraj Kunjiappan
Published 2019 · Materials Science

Cite This
Download PDF
Analyze on Scholarcy
Share
The main focus of present study is to optimize the extraction parameters for maximum yield of biomass, β-carotene and chlorophyll content and their antioxidants from Kappaphycus alvarezii by response surface methodology (RSM) along with adaptive neuro-fuzzy inference system (ANFIS). Central composite rotatable design of RSM was applied to optimize the effect of microwave-assisted extraction (MAE) parameters. In this way, four parameters, such as methanol concentration (X1: 65–80%), microwave power (X2: 15–20%), radiation induced temperature (X3: 45–60 °C) and radiation exposure time (X4: 7.5–15 min) at five levels were selected. Optimal conditions were found as X1 = 80%, X2 = 20%, X3 = 45 °C and X4 = 12.5–14.5 min, under this condition, % yield of biomass (y1) = 86.231–87.212%, β-carotene and chlorophyll content (y2) = 77.348–82.841 mg/gm, %DPPHsc (y3) = 69.362–72.768%, %ABTSsc (y4) = 66.282–70.621%, FRAP (y5) = 62.654–64.381 μg mol (Fe(II))/g has been obtained. Also, optimized values of MAE parameters were compared and verified with ANFIS. Further, the major bioactive compounds present in the optimally obtained extract of K. alvarezii was identified through FTIR, gas chromatography-mass spectrum and HPLC.
This paper references
10.1007/s10811-010-9570-2
The commercial red seaweed Kappaphycus alvarezii—an overview on farming and environment
M. S. Bindu (2010)
10.1016/c2013-0-08304-1
Readings in Fuzzy Sets for Intelligent Systems
M. Dubois (1993)
10.1021/NP068054V
Natural products as sources of new drugs over the last 25 years.
D. Newman (2007)
10.1016/J.ALGAL.2012.10.001
Microwave assisted lipid extraction from microalgae using biodiesel as co-solvent
J. Iqbal (2013)
10.1007/s10811-016-0974-5
Algae as nutritional and functional food sources: revisiting our understanding
M. Wells (2016)
10.1016/J.IFSET.2011.09.004
Supercritical fluid extraction of astaxanthin from Haematococcus pluvialis and its antioxidant potential in sunflower oil
Lingzhao Wang (2012)
10.1016/J.FCT.2006.01.011
Antiproliferative and antioxidant properties of an enzymatic hydrolysate from brown alga, Ecklonia cava.
Yasantha Athukorala (2006)
10.2174/2213335605666180528084153
Optimization of Microwave-assisted Extraction of Bioactive Compounds from Dunaliella bardawil Using RSM and ANFIS Modeling and Assessment of the Anticancer Activity of Bioactive Compounds
Selvaraj Kunjiappan (2019)
10.1002/elsc.201400191
Algae as production systems of bioactive compounds
I. Michalak (2015)
10.1016/J.TIFS.2008.08.004
Nutraceuticals and functional foods: Whole versus processed foods
F. Shahidi (2009)
10.1002/PCA.631
Recent extraction techniques for natural products: microwave-assisted extraction and pressurised solvent extraction.
B. Kaufmann (2002)
10.17221/6758-VETMED
Carrageenan: a review.
J. Nečas (2018)
10.2174/138161209789058084
Antioxidant effects of natural bioactive compounds.
C. Balsano (2009)
10.1007/s11694-017-9634-y
Optimization and analysis of microwave-assisted extraction of bioactive compounds from Mimosa pudica L. using RSM & ANFIS modeling
V. Ganesan (2017)
10.2174/1871520618666180628155223
Design Graph Theoretical Analysis and In Silico Modeling of Dunaliella Bardawil Biomass Encapsulated N-Succinyl Chitosan Nanoparticles for Enhanced Anticancer Activity.
Selvaraj Kunjiappan (2018)
10.1021/np200906s
Natural products as sources of new drugs over the 30 years from 1981 to 2010.
D. Newman (2012)
10.3390/md14020034
Marine Origin Polysaccharides in Drug Delivery Systems
M. J. Cardoso (2016)
10.1016/J.CHERD.2013.10.001
Modeling and Kinetics Study of Conventional and Assisted Batch Solvent Extraction
Chung-Hung Chan (2014)
10.1093/GLYCOB/CWM014
A comparative study of the anti-inflammatory, anticoagulant, antiangiogenic, and antiadhesive activities of nine different fucoidans from brown seaweeds.
A. Cumashi (2007)
10.3390/molecules190811679
Review of Natural Compounds for Potential Skin Cancer Treatment
Tawona N. Chinembiri (2014)
10.1006/BBRC.2001.4663
Crystal structure of a light-harvesting protein C-phycocyanin from Spirulina platensis.
A. K. Padyana (2001)
10.1016/j.biopha.2016.12.092
The properties of red seaweed (Kappaphycus alvarezii) and its effect on mammary carcinogenesis.
Vi-Sion Chang (2017)
10.1006/ABIO.1996.0292
The ferric reducing ability of plasma (FRAP) as a measure of "antioxidant power": the FRAP assay.
I. Benzie (1996)
10.1016/J.JFOODENG.2013.01.014
Techniques for extraction of bioactive compounds from plant materials: A review
J. Azmir (2013)
10.1007/s12161-015-0370-9
Optimization of Extraction of Bioactive Compounds from Black Carrot Using Response Surface Methodology (RSM)
Burcu Guldiken (2015)
10.1088/1748-605X/aabcea
Design, graph theoretical analysis and in silico modeling of Dunaliella bardawil biomass encapsulated keratin nanoparticles: a scaffold for effective glucose utilization.
Selvaraj Kunjiappan (2018)
10.1155/2014/462623
Erratum to “Does Urinary Bladder Shape Affect Urinary Flow Rate in Men with Lower Urinary Tract Symptoms?”
Y. Z. Ateşçi (2014)
HPLC chromatogram of optimally obtained extract of K. alvarezii 2789 Optimization of bioactive compounds extraction assisted by microwave parameters from.
J. Iqbal (2013)
Sci
S. Zorofchian Moghadamtousi (2014)
10.1002/jssc.201200231
Isolation of fucoxanthin from edible brown algae by microwave-assisted extraction coupled with high-speed countercurrent chromatography.
Xiaohua Xiao (2012)
10.1111/1541-4337.12005
Technologies for Extraction and Production of Bioactive Compounds to be Used as Nutraceuticals and Food Ingredients: An Overview
G. J. Gil-Chavez (2013)
10.1016/j.foodres.2018.07.021
Microwave assisted extraction of phenolic compounds from four economic brown macroalgae species and evaluation of their antioxidant activities and inhibitory effects on α-amylase, α-glucosidase, pancreatic lipase and tyrosinase.
Y. Yuan (2018)
10.1016/J.CARBPOL.2010.10.062
Biological activities and potential health benefits of sulfated polysaccharides derived from marine algae
I. Wijesekara (2011)
10.1007/BF00003544
Microalgae as sources of pharmaceuticals and other biologically active compounds
M. Borowitzka (2004)
10.1007/s10811-010-9632-5
Bioactive compounds in seaweed: functional food applications and legislation
S. L. Holdt (2010)
10.1016/J.TIFS.2011.09.001
Seaweeds: A sustainable functional food for complementary and alternative therapy
S. Mohamed (2012)
10.1080/01496390802282321
Optimization of Microwave-Assisted Extraction of Astaxanthin from Haematococcus Pluvialis by Response Surface Methodology and Antioxidant Activities of the Extracts
Liyan Zhao (2009)
10.1021/JF9913458
Antioxidant activity of dietary polyphenols as determined by a modified ferric reducing/antioxidant power assay.
R. Pulido (2000)
10.5772/51572
Algal Polysaccharides, Novel Applications and Outlook
S. Kraan (2012)
10.1002/9783527679577.CH26
Algal Polysaccharides and Their Biological Applications
Sirisha L. Vavilala (2015)
10.1016/J.RSER.2017.03.135
The application of microwave heating in bioenergy: A review on the microwave pre-treatment and upgrading technologies for biomass
E. T. Kostas (2017)
10.1016/J.JFF.2015.06.018
Phenolics and polyphenolics in foods, beverages and spices: Antioxidant activity and health effects – A review
F. Shahidi (2015)
10.1155/2014/768323
Anticancer and Antitumor Potential of Fucoidan and Fucoxanthin, Two Main Metabolites Isolated from Brown Algae
Soheil Zorofchian Moghadamtousi (2014)



This paper is referenced by
Semantic Scholar Logo Some data provided by SemanticScholar