← Back to Search
Recent Advances In The Physiology Of Spore Formation For Bacillus Probiotic Production
V. Elisashvili, E. Kachlishvili, M. Chikindas
Published 2018 · Biology, Medicine
Save to my Library
Download via 🐼 PaperPanda Download via oaDOI Download via OAB Download via LibKey Download via Google Google ScholarAnalyze on Scholarcy Visualize in Litmaps
Reduce the time it takes to create your bibliography by a factor of 10 by using the world’s favourite reference manager
Time to take this seriously.
Spore-forming probiotic bacteria have received a wide and constantly increasing scientific and commercial interest. Among them, Bacillus species are the most studied and well-characterized Gram-positive bacteria. The use of bacilli as probiotic products is expanding especially rapidly due to their inherent ability to form endospores with unique survivability and tolerance to extreme environments and to produce a large number of valuable metabolites coupled with their bio-therapeutic potential demonstrating immune stimulation, antimicrobial activities and competitive exclusion. Ease of Bacillus spp. production and stability during processing and storage make them a suitable candidate for commercial manufacture of novel foods or dietary supplements for human and animal feeds for livestock, especially in the poultry and aquaculture industries. Therefore, the development of low-cost and competitive technologies for the production of spore-forming probiotic bacteria through understanding physiological peculiarities and mechanisms determining the growth and spore production by Bacillus spp. became necessary. This review summarizes the recent literature and our own data on the physiology of bacilli growth and spore production in the submerged and solid-state fermentation conditions, focusing on the common characteristics and unique properties of individual bacteria as well as on several approaches providing enhanced spore formation.
This paper references
Topley and Wilson's Principles of Bacteriology, Virology and Immunity
B. A. D. Stocker (1976)
Single, chemically defined sporulation medium for Bacillus subtilis: growth, sporulation, and extracellular protease production
J. Hageman (1984)
Probiotics in man and animals.
R. Fuller (1989)
Energy and calcium ion dependence of proteolysis during sporulation of Bacillus subtilis cells
M. B. O'Hara (1990)
α-Amylase production by thermophilic Bacillus coagulans in solid state fermentation
K. R. Babu (1995)
Enhanced sporulation in Bacillus subtilis grown on medium containing glucose:ribose
K. Warriner (1999)
High-cell-density cultivation of microorganisms
D. Riesenberg (1999)
Control of sporulation initiation in Bacillus subtilis.
A. Sonenshein (2000)
Characterization of Bacillus Species Used for Oral Bacteriotherapy and Bacterioprophylaxis of Gastrointestinal Disorders
N. T. Hoa (2000)
Role of Dipicolinic Acid in Survival ofBacillus subtilis Spores Exposed to Artificial and Solar UV Radiation
Tony A. Slieman (2001)
Isolation, identification and evaluation of bacterial antagonists against Botrytis elliptica on lily
A. Chiou (2001)
Histological alterations of intestinal villi in chickens fed dried Bacillus subtilis var. natto.
M. Samanya (2002)
Production of a biocontrol agent for crucifers black rot disease
C. L. Luna (2002)
Production of iturin A by Bacillus amyloliquefaciens suppressing Rhizoctonia solani
G. Yu (2002)
Guidelines for the evaluation of probiotics in food
Fao Who (2002)
Biotechnological advantages of laboratory-scale solid-state fermentation with fungi
U. Hölker (2003)
Bacterial direct-fed microbials in ruminant diets: Performance response and mode of action
C. Krehbiel (2003)
Sporeformers as Human Probiotics: Bacillus, Sporolactobacillus, and Brevibacillus.
M. Sanders (2003)
Natto-A food made by fermenting cooked soybeans with Bacillus subtilis (natto)
T. Hosoi (2003)
Optimization of agitation, aeration, and temperature conditions for maximum β-mannanase production
Yaoyu Feng (2003)
Effects of Lactobacilli and an acidophilic fungus on the production performance and immune responses in broiler chickens.
M. K. Huang (2004)
Bacillus spores as probiotic products for human use.
S. Senesi (2004)
Spore probiotics as animal feed supplements.
Stephen T. Cartman (2004)
Modeling and optimization of the process conditions for biomass production and sporulation of a probiotic culture
R. Sen (2005)
Lactic acid bacteria and their uses in animal feeding to improve food safety.
M. M. Brashears (2005)
Screening for Bacillus Isolates in the Broiler Gastrointestinal Tract
T. M. Barbosa (2005)
pH-, Lactic Acid-, and Non-Lactic Acid-Dependent Activities of Probiotic Lactobacilli against Salmonella enterica Serovar Typhimurium
D. Fayol-Messaoudi (2005)
The use of bacterial spore formers as probiotics.
H. Hong (2005)
A Procedure for High‐Yield Spore Production by Bacillus s ubtilis
S. Monteiro (2005)
Influence of Glutamate on Growth, Sporulation, and Spore Properties of Bacillus cereus ATCC 14579 in Defined Medium
Y. D. de Vries (2005)
Solid Culturing of Bacillus amyloliquefaciens for α-Amylase Production
D. Gangadharan (2006)
Bacillus thuringiensis and Bacillus sphaericus biopesticides production
M. El-Bendary (2006)
Application of statistically-based experimental designs in medium optimization for spore production of Bacillus subtilis from distillery effluent
Fengyu Shi (2006)
Effect of Bacillus licheniformis and Bacillus subtilis supplementation of ewe's feed on sheep milk production and young lamb mortality.
S. Kritas (2006)
Effects of a dried Bacillus subtilis culture on egg quality.
L. Li (2006)
Dietary probiotic supplementation and resulting effects on performance, health status, and microbial characteristics of primiparous sows.
B. M. Böhmer (2006)
Solid culturing of Bacillus amyloliquefaciens for alpha amylase production
D Gangadharan (2006)
The Potential Role of Concentrated Animal Feeding Operations in Infectious Disease Epidemics and Antibiotic Resistance
M. Gilchrist (2007)
On the use of a probiotic (Bacillus subtilis - strain DSM 17299) as growth promoter in broiler diets
M. Opaliński (2007)
High-yield spore production from Bacillus licheniformis by solid state fermentation
S. Zhao (2007)
Survivability of a probiotic Lactobacillus casei in the gastrointestinal tract of healthy human volunteers and its impact on the faecal microflora
K. Tuohy (2007)
Medium optimization of carbon and nitrogen sources for the production of spores from Bacillus amyloliquefaciens B128 using response surface methodology
Y. Rao (2007)
Germination and outgrowth of Bacillus subtilis and Bacillus licheniformis spores in the gastrointestinal tract of pigs
T. D. Leser (2008)
Bacillus subtilis Spores Germinate in the Chicken Gastrointestinal Tract
Stephen T. Cartman (2008)
Effect of cultivation conditions on spore production from Bacillus amyloliquefaciens B128 and its antagonism to Botrytis elliptica
Y-M Tzeng (2008)
Greater enhancement of Bacillus subtilis spore yields in submerged cultures by optimization of medium composition through statistical experimental designs
Zhen-Min Chen (2009)
Feeding beneficial bacteria: A natural solution for increasing efficiency and decreasing pathogens in animal agriculture
J. F. Flint (2009)
Inexpensive fed-batch cultivation for high poly(3-hydroxybutyrate) production by a new isolate of Bacillus megaterium.
Songsri Kulpreecha (2009)
A new strategy to apply Bacillus subtilis MA139 for the production of solid‐state fermentation feed
W. Ying (2009)
The potential benefits of probiotics in animal production and health.
H. Musa (2009)
Effects of Bacillus subtilis var. natto and Saccharomyces cerevisiae mixed fermented feed on the enhanced growth performance of broilers.
K.-L. Chen (2009)
Evaluation of Multi-microbial Probiotics Produced by Submerged Liquid and Solid Substrate Fermentation Methods in Broilers
Y. H. Shim (2010)
Multi-objective process optimization and integration for the sequential and increased production of biomass, lipase and endospores of a probiotic bacterium.
S. Das (2010)
Probiotics and prebiotics in animal feeding for safe food production.
F. Gaggìa (2010)
The potential of probiotics: a review.
C. Soccol (2010)
Evaluation of multi-microbe probiotics prepared by submerged liquid or solid substrate fermentation and antibiotics in weaning pigs
J. Choi (2011)
Effect of different concentrations of Bacillus subtilis on growth performance, carcase quality, gut microflora and immune response of broiler chickens
A. Molnár (2011)
Probiotics and health: an evidence-based review.
P. Aureli (2011)
Probiotics market size , share & trends analysis report by application ( food & beverages , dietary supplements , animal feed ) , by end - use , by region , and segment forecast , 2018 – 2024
P Aureli (2011)
Effect of supplementation of Bacillus subtilis LS 1-2 to broiler diets on growth performance, nutrient retention, caecal microbiology and small intestinal morphology.
S. Sen (2012)
Bacillus subtilis Endospores at High Purity and Recovery Yields: Optimization of Growth Conditions and Purification Method
M. B. Tavares (2012)
Protection activity of a novel probiotic strain of Bacillus subtilis against Salmonella Enteritidis infection.
M. Thirabunyanon (2012)
Bacillus subtilis: from soil bacterium to super-secreting cell factory
J. V. van Dijl (2013)
Isolation and characterization of different strains of Bacillus licheniformis for the production of commercially significant enzymes.
Maria Ghani (2013)
Characterization of Bacillus spp. strains for use as probiotic additives in pig feed
N. Larsen (2013)
Non-digestible long chain beta-glucans as novel prebiotics
K. Lam (2013)
Probiotics from research to market: the possibilities, risks and challenges.
B. Foligné (2013)
Enhanced viability of Lactobacillus reuteri for probiotics production in mixed solid-state fermentation in the presence of Bacillus subtilis
Yi-ran Zhang (2013)
A second-generation Bacillus cell factory for rare inositol production
Kosei Tanaka (2014)
A new chemically defined medium for the growth and sporulation of Bacillus cereus strains in anaerobiosis.
A. Abbas (2014)
Enhanced Spore Production of Bacillus subtilis Grown in a Chemically Defined Medium
S. Monteiro (2014)
Effects of dietary supplementation with Bacillus subtilis LS 1–2 fermentation biomass on growth performance, nutrient digestibility, cecal microbiota and intestinal morphology of weanling pig
S. Lee (2014)
A statistical approach for the production of thermostable and alklophilic alpha-amylase from Bacillus amyloliquefaciens KCP2 under solid-state fermentation
Vimal S Prajapati (2014)
Low cost medium for spore production of Bacillus KKU02 and KKU03 and the effects of the produced spores on growth of giant freshwater prawn (Macrobrachium rosenbergii de Man).
C. Wangka-orm (2014)
Current Developments in Probiotics
C. Soccol (2015)
Poultry-beneficial solid-state Bacillus amyloliquefaciens B-1895 fermented soybean formulation
V. Chistyakov (2015)
Antibacterial activity and genotypic-phenotypic characteristics of bacteriocin-producing Bacillus subtilis KKU213: potential as a probiotic strain.
Nalisa Khochamit (2015)
Comparison of Microbiological and Probiotic Characteristics of Lactobacilli Isolates from Dairy Food Products and Animal Rumen Contents
N. Jose (2015)
Effect of medium components and culture conditions in Bacillus subtilis EA-CB0575 spore production
Luisa F. Posada-Uribe (2015)
The toxic effects of combined aflatoxins and zearalenone in naturally contaminated diets on laying performance, egg quality and mycotoxins residues in eggs of layers and the protective effect of Bacillus subtilis biodegradation product.
Ru Jia (2016)
Multistrain Probiotics: The Present Forward the Future
V. Giacchi (2016)
PRODUCTION OF CELLULASES AND XYLANASE FROM BACILLUS SUBTILIS MU S1 ISOLATED FROM PROTECTED AREAS OF MUNNAR WILDLIFE DIVISION
Sreena C.P (2016)
Development of bioprocess for high density cultivation yield of the probiotic Bacillus coagulans and its spores
Kavita R. Pandey (2016)
Bacillus As Potential Probiotics: Status, Concerns, and Future Perspectives
Fouad M. F. Elshaghabee (2017)
OPTIMIZATION OF ENHANCED PROBIOTIC SPORES PRODUCTION IN SUBMERGED CULTIVATION OF BACILLUS AMYLOLIQUEFACIENS B-1895
Tamar Khardziani (2017)
Bacillus amyloliquefaciens Spore Production Under Solid-State Fermentation of Lignocellulosic Residues
V. Berikashvili (2017)
Elucidation of Bacillus subtilis KATMIRA 1933 Potential for Spore Production in Submerged Fermentation of Plant Raw Materials
Tamar Khardziani (2017)
Bacillus Probiotic Supplementations Improve Laying Performance, Egg Quality, Hatching of Laying Hens, and Sperm Quality of Roosters
M. Mazanko (2017)
A review on application of probiotic, prebiotic and synbiotic for sustainable development of aquaculture
S. Das (2017)
Rapid optimization of spore production from Bacillus amyloliquefaciens in submerged cultures based on dipicolinic acid fluorimetry assay
Hang Ren (2018)
Bacillus subtilis with endocellulase and exocellulase activities isolated in the thermophilic phase from composting with coffee residues.
Yadira Siu-Rodas (2018)
Probiotics and Prebiotics: An Overview on Recent Trends
G. Zoumpopoulou (2018)
Bacillus probiotics: an alternative to antibiotics for livestock production
S. Mingmongkolchai (2018)
Genome Sequence of the Probiotic Strain Bacillus velezensis Variant polyfermenticus GF423
H. Jeong (2018)
Spores and Their Significance
P. Setlow (2019)
This paper is referenced by
A Review of the Effects and Production of Spore-Forming Probiotics for Poultry
I. Popov (2021)
Production and stability of a multi-strain Bacillus based probiotic product for commercial use in poultry
Uraisha Ramlucken (2021)
Bacillus subtilis natto as a potential probiotic in animal nutrition
Sandra R B Ruiz Sella (2021)
Diversity and biotechnological potential of endophytic Bacillus species originating from the stem apoplast fluid of sugarcane plants
Leona Henrique Varial de Melo (2021)
Bacillus subtilis-Based Probiotic Improves Skeletal Health and Immunity in Broiler Chickens Exposed to Heat Stress
Sha-Sha Jiang (2021)
Dietary supplementation with Bacillus mixture modifies the intestinal ecosystem of weaned piglets in an overall beneficial way
Xiaodan Wang (2020)
Stabilizing enzymes by immobilization on bacterial spores: A review of literature.
Chika Jude Ugwuodo (2020)
Improving probiotic spore yield using rice straw hydrolysate
L. Yin (2020)
Enhancement of the Anti-inflammatory Effect of Bromelain by Its Immobilization on Probiotic Spore of Bacillus cereus
Chika Jude Ugwuodo (2020)
Probiotics in shellfish aquaculture
E. Ringø (2020)
Optimization of a culture medium based on forage palm for δ-endotoxin production
T. A. F. da Silva (2020)
New Bacillus spp. with potential for 2,3-butanediol production from biomass.
P. Petrova (2020)
The Bacteria-gut-brain Axis: Gut Bacteria as a Key Regulator of Social Stress and Stress-related Injurious Behaviors in Chickens
Sha-Sha Jiang (2020)
Phosphorus Solubilization and Mobilization: Mechanisms, Current Developments, and Future Challenge
Dhavalkumar Patel (2020)
Bacillus spp. Spores—A Promising Treatment Option for Patients with Irritable Bowel Syndrome
A. Catinean (2019)
Gut-Brain Axis: Probiotic, Bacillus subtilis , Prevents Aggression via the Modification of the Central Serotonergic System
H. Cheng (2019)
Evaluation of an Industrial Soybean Byproduct for the Potential Development of a Probiotic Animal Feed Additive with Bacillus Species
Rachel Mahoney (2019)