Online citations, reference lists, and bibliographies.
Referencing for people who value simplicity, privacy, and speed.
Get Citationsy
← Back to Search

Surfactant-induced Release Of Liposomal Contents. A Survey Of Methods And Results.

J. Ruíz, F. Goñi, A. Alonso
Published 1988 · Chemistry, Medicine

Save to my Library
Download PDF
Analyze on Scholarcy Visualize in Litmaps
Share
Reduce the time it takes to create your bibliography by a factor of 10 by using the world’s favourite reference manager
Time to take this seriously.
Get Citationsy
A systematic approach to the phenomenon of surfactant-dependent release of liposomal contents has been attempted. A variety of methods have been comparatively studied. The influence of the size of the entrapped molecule, nature of the surfactant, composition of bilayers and sonication of liposomes have been considered separately. In order to compare different results, a parameter has been defined, R50, as the phospholipid/surfactant mole ratio producing 50% release of the entrapped solute. This parameter appears to be, to a large extent, independent of time and liposome concentration. Surfactant-induced release of liposomal contents does not occur as a result of breakdown of phospholipid bilayers, but is rather a different phenomenon, occurring at detergent concentrations substantially lower (2-5 times) than solubilization. The required amount of surfactant appears to increase with the size of the entrapped solute. R50 depends clearly on the nature of the soluble amphiphile, but there is no obvious relationship with its critical micellar concentration. Liberation of vesicle content also depends on bilayer composition: phospholipids have various effects on the stability of the membrane, while the hydrophobic peptide, gramicidin A, appears to have little influence. Cholesterol is interesting, since at equimolar proportions with phosphatidylcholine, it decreases the stability of bilayer towards Triton X-100, while increasing it in the presence of cholate. Sonication also exerts an influence on the surfactant-dependent release of vesicle contents; it appears to decrease the bilayer stability, so that lower detergent concentrations are required to liberate the entrapped solutes. Finally, it should be noted that, although the decrease in self-quenching of 6-carboxyfluorescein is a convenient method for the study of solute liberation, glucose release, as detected by enzymatic methods, may be more reliable for accurate measurements.
This paper references
10.1016/0005-2736(87)90383-X
The influence of membrane composition on the solubilizing effects of Triton X-100.
M. Urbaneja (1987)
10.1016/S0006-3495(78)85500-3
Equilibrium studies of lecithin-cholesterol interactions I. Stoichiometry of lecithin-cholesterol complexes in bulk systems.
N. L. Gershfeld (1978)
10.1126/SCIENCE.835007
Liposome-cell interaction: transfer and intracellular release of a trapped fluorescent marker.
J. Weinstein (1977)
10.1016/0304-4157(75)90016-7
Solubilization of membranes by detergents.
A. Helenius (1975)
10.1016/0304-4157(83)90004-7
Solubilization of phospholipids by detergents. Structural and kinetic aspects.
D. Lichtenberg (1983)
10.1016/0003-9861(84)90228-5
Lysophosphatidylcholine cell depolarization: increased membrane permeability for use in the determination of cell membrane potentials.
R. Gallo (1984)
10.1016/0076-6879(79)56066-2
[63] Properties of detergents
A. Helenius (1979)
10.1016/0014-5793(81)80287-6
Lysis and reassembly of sonicated lecithin vesicles in the presence of triton X‐100
A. Alonso (1981)
10.1111/J.1432-1033.1986.TB10088.X
The interaction of phosphatidylcholine bilayers with Triton X-100.
F. Goñi (1986)
10.1021/BI00583A013
Structural and kinetic studies on the solubilization of lecithin by sodium deoxycholate.
D. Lichtenberg (1979)
10.1017/S0033583500001797
Phase transitions and fluidity characteristics of lipids and cell membranes.
D. Chapman (1975)
10.1159/000198984
Studies on the mechanism of bile salt-induced liposomal membrane damage.
R. Schubert (1983)
10.1016/0005-2736(76)90424-7
Effect of lipid composition on sensitivity of lipid membranes to Triton X-100.
K. Inoue (1976)
10.1016/0005-2736(85)90072-0
Bile salt damage of egg phosphatidylcholine liposomes.
C. O'connor (1985)
10.1016/s0021-9258(18)70226-3
Phosphorus assay in column chromatography.
G. R. Bartlett (1959)
10.1126/SCIENCE.195.4277.480
Quandaries for american scholars.
D. Joravsky (1977)
10.1177/000456326900600108
Determination of Glucose in Blood Using Glucose Oxidase with an Alternative Oxygen Acceptor
P. Trinder (1969)
10.1016/0005-2736(78)90275-4
The interaction of detergents with bilayer lipid membranes.
J. Bangham (1978)
10.1016/0022-2836(77)90236-4
Interactions of helical polypeptide segments which span the hydrocarbon region of lipid bilayers: Studies of the gramicidin alipid-water system
D. Chapman (1977)
10.1016/0005-2736(83)90102-5
Membrane-surfactant interactions. The effect of Triton X-100 on sarcoplasmic reticulum vesicles.
A. Prado (1983)
10.1016/0003-9861(77)90343-5
Triton X-100 as a channel-forming substance in artificial lipid bilayer membranes.
P. Schlieper (1977)
10.1016/0005-2736(87)90301-4
Kinetic studies on the interaction of phosphatidylcholine liposomes with Triton X-100.
A. Alonso (1987)



This paper is referenced by
10.1016/j.bpj.2013.06.007
The mechanism of detergent solubilization of lipid bilayers.
D. Lichtenberg (2013)
10.1016/S0001-8686(00)00081-6
Properties of the amphiphilic films in mixed cationic/anionic vesicles: a comprehensive view from a literature analysis.
C. Tondre (2001)
10.1007/BF00654745
Assembly properties of Triton X-100/phosphatidylcholine aggregates during liposome solubilization
A. D. L. Maza (1996)
10.1016/0005-2736(89)90547-6
The integrity of proteoliposomes adsorbed on a biosurface
F. J. Hutchinson (1989)
10.1021/la201438s
Interaction of ionic surfactants with cornea-mimicking anionic liposomes.
C. Gupta (2011)
10.1016/S0927-7757(99)00246-0
Solubilization of stratum corneum lipid liposomes by C14-betaine/sodium dodecyl sulfate mixtures. Influence of the level of ceramides in the solubilization process
O. López (2000)
10.1002/ANGE.19951071905
Die cytomimetische organische Chemie — ein erster Bericht
F. Menger (1995)
10.1016/S0304-4157(00)00011-3
Spectroscopic techniques in the study of membrane solubilization, reconstitution and permeabilization by detergents.
F. Goñi (2000)
10.1016/0005-2736(90)90111-Z
Interaction of Triton X-100 and octyl glucoside with liposomal membranes at sublytic and lytic concentrations. Spectroscopic studies.
J. Lasch (1990)
10.1016/0005-2736(89)90200-9
The solubilization and morphological change of human platelets in various detergents.
Y. Shiao (1989)
10.1016/j.cbpa.2012.05.182
Miniaturized bioanalytical systems: enhanced performance through liposomes.
K. Edwards (2012)
10.1016/0731-7085(94)90004-3
Effects of surfactants on the spectral behaviour of calcein.
A. Memoli (1994)
10.1074/JBC.271.43.26616
Different Effects of Enzyme-generated Ceramides and Diacylglycerols in Phospholipid Membrane Fusion and Leakage*
M. Ruiz-Argüello (1996)
10.3109/08982109909044492
Optimization of Drug Loading Procedures and Characterization of Liposomal Formulations of Two Novel Agents Intended for Boron Neutron Capture Therapy (BNCT)
M. Johnsson (1999)
10.1017/S0033583508004721
Interactions of surfactants with lipid membranes.
H. Heerklotz (2008)
10.1016/0378-5173(94)90440-5
AN INVESTIGATION INTO THE EFFECTS OF SURFACTANTS ON PHOSPHOLIPID MONOLAYERS USING A LANGMUIR-BLODGETT-FILM BALANCE
N.M.W. Ah-Fat (1994)
10.1016/S0378-4347(97)00517-3
Methodology for vesicle permeability study by high-performance gel exclusion chromatography.
K. Andrieux (1998)
10.1021/ja3051876
A self-assembled delivery platform with post-production tunable release rate.
J. Boekhoven (2012)
10.3139/113.110125
AOT-Vesicles Produced at the Oil-Water Interface
E. A. Kubatta (2011)
10.1007/BF00659286
Solubilization of unilamellar phospholipid bilayers by nonionic surfactants
A. D. L. Maza (1994)
10.1529/BIOPHYSJ.105.076471
Sphingosine increases the permeability of model and cell membranes.
F. Contreras (2006)
10.1016/0003-9861(88)90409-2
Sublytic and lytic effects of the zwitterionic bile derivative 3-((3-deoxycholamidopropyl)dimethylammonio)-1-propanesulfonate on phosphatidylcholine liposomes.
M. A. Partearroyo (1988)
10.1007/BF02517989
Solubilizing effects caused by the nonionic surfactant octyl glucoside in phosphatidylcholine liposomes
A. Maza (1996)
10.1016/S0378-5173(98)00345-7
Surfactants in membrane solubilisation.
M. Jones (1999)
10.1016/S0927-7757(98)00212-X
INTERACTION OF THE GLYCOPROTEIN EXCRETED BY PSEUDOALTEROMONAS ANTARCTICA NF3 WITH PHOSPHATIDYLCHOLINE LIPOSOMES
A. D. L. Maza (1998)
10.1016/S0005-2736(97)00265-4
The aminosterol antibiotic squalamine permeabilizes large unilamellar phospholipid vesicles.
B. Selinsky (1998)
Parallel sampling from individual cells on a microchip : towards a parallel single cell analysis platform
E. V. D. Brink (2011)
10.1016/S0168-3659(97)00205-8
Subsolubilizing alterations caused by alkyl glucosides in phosphatidylcholine liposomes.
A. de la Maza (1998)
10.1007/BF02641006
Solubilization of phospholipid bilayer caused by surfactants
A. Maza (1993)
10.1016/0005-2736(89)90219-8
Solubilization of DMPC and DPPC vesicles by detergents below their critical micellization concentration: high-sensitivity differential scanning calorimetry, Fourier transform infrared spectroscopy and freeze-fracture electron microscopy reveal two interaction sites of detergents in vesicles.
T. Bayerl (1989)
10.1039/CS9922100127
Surfactant interactions with biomembranes and proteins
M. Jones (1992)
10.1007/BF00665642
Alterations in phospholipid bilayers caused by sodium dodecyl sulphate/triton X-100 mixed systems
A. D. L. Maza (1996)
See more
Semantic Scholar Logo Some data provided by SemanticScholar