Online citations, reference lists, and bibliographies.

The Relationship Between The Structural And Orthogonal Compressive Properties Of Trabecular Bone.

R. Goulet, S. Goldstein, M. Ciarelli, J. Kuhn, M. B. Brown, L. Feldkamp
Published 1994 · Engineering, Medicine

Cite This
Download PDF
Analyze on Scholarcy
In this study, cubes of trabecular bone with a wide range of structural properties were scanned on a micro-computed tomography system to produce complete three-dimensional digitizations from which morphological and architectural parameters could be measured in a nondestructive manner. The cubes were then mechanically tested in uniaxial compression in three orthogonal directions and to failure in one direction to find the orthogonal tangent elastic moduli and ultimate strengths. After testing, the cubes were weighed and ashed to determine the apparent and ash densities. A high correlation between the basic stereologic measurements was found, indicating that there is a relationship between the amount of bone and number of trabeculae in cancellous bone. Regression analysis was used to estimate the modulus and ultimate strength; these regressions accounted for 68-90% of the variance in these measures. These relationships were dependent on the metaphyseal type and donor, with the modulus also dependent on the direction of testing. This indicates that the properties of the individual trabeculae, as well as their amount and organization, may be important in predicting the mechanical properties of cancellous bone.
This paper references
1989bl Stereolonic assessment of ‘trabecular st&ure in‘ the lbmbar ve;tebral
A A.III. (1989)
A quantitative The scanning el & rin microscope in studies of trabecular histological study of bone formation in human cancellous bone from a human vertebra 1 body
J. L. Williams
1970b) A quantitative The scanning el&rin microscope in studies of trabecular histological study of bone formation in human cancellous bone from a human vertebra1
E. D. Whitehouse. W.J.. Dvson (1970)
The architecture of cancellous bone.
I. Singh (1978)
Alterations of trabecuGoldstein
M. B. Schaffler (1992)
Variation in trabecular structure
P. J. Atkinson (1967)
Predicting the architectural orientation logy
R. W. Goulet
The mechanical behaviour of cancellous bone.
L. Gibson (1985)
On the tomography
S. C. Cowin (1988)
The effect of constraint on the mechanical behaviour of trabecular bone specimens.
F. Linde (1989)
Elastic and mechanics 22 , 901910 . viscoelastic properties of trabecular bone : dependence on
J. W. J. Bio-Pugh (1973)
Trabecular architecture of the human and Kleerekoper, M
P. Raux (1975)
J. orthop. Res
A quantitative The scanning el&rin microscope in studies of trabecular histological study of bone formation in human cancellous bone from a human vertebra1 body
W J Whitehouse (1970)
Measurement of anisotropic vertebral trabecular bone loss during aging by quantitative image analysis
C. Bergot (1988)
The compressive behavior of bone as a two-phase porous structure.
D. Carter (1977)
The relationship between the elasticity menclature, symbols, and units
S. C. Cowin (1985)
Evaluation of orthogonal mechanical bone specimens
S. A. Goldstein (1991)
Trabecuiar bone structure and mechanical Turner, C. H
J. L. Kuhn (1987)
The underestimation of Young's modulus in compressive testing of cancellous bone specimens.
A. Odgaard (1991)
Practi - structure
L. A. Feldkamp (1984)
Evaluation of a microcomouted tomography system tb study trabecular bone structure . off - axis measurements of the elastic properties of bone
J. L. Kuhn
Wolff's law of trabecular architecture at remodeling equilibrium.
S. Cowin (1986)
Stereological Methods , Vol 1 : Practical bone specimens
I. Hvid
A study of variation of trabecular architecelastic constants of cancellous bone
The direct examination of patella
P. Raux
Methods for Biological Morphometry The effect of constraint on the London
F Linde (1979)
and Young's modulus in compressive testing of cancellous Evaluation of orthogonal mechanical bone specimens 691-698. properties and density of human trabecular bone from the Parfitt
A Odgaard (1991)
Bone mineralassay: its relation to the mechan
J C. (1985)
Boundary length and internal surface properties University of Michigan, area measurements in porous materials with elliptical Ann Arbor
J L Kuhn (1986)
485-490. ical Foundations
J. biomed. Engng
A Odgaard (1990)
Toward a quantitative formulation of Wol5''s law in trabecular bone
W. Hayes (1981)
Mechanical property distributions in the cancellous bone of the human proximal femur.
T. Brown (1980)
Bone mineralassay : its relation to the mechanbiomechanical implications
I. Hvid (1985)
anisotropic model of cancellous bone from the proximal ( 1990 ) Effects of prostaglandin E , on production of new tibia 1 epiphysis
W. S. S. Jee (1982)
Image Analysis and Mathematical Morphostein
R. W. Goulet (1982)
microstructural anisotropy in orthotropic materials using (1989a) Anisotropic structure-property relation for traa second rank tensor
T. P. 305-310. Harrigan (1989)
Quantitative Stereology. Addisonanics Meeting
Tomography System (1970)
Quantitative structural analysis of human cancellous bone.
W. A. Merz (1970)
ships between surface, volume and thickness of iliac traMathematical modelling of trabecular bone structure: the becular bone in aging and in osteoporosis
N. L. Fazzalari (1989)
A study of variation of trabecular architecelastic constants of cancellous bone
C. H. Turner
Errors induced by and Jesion
J. L. Kuhn (1988)
The distribution and anisotropy of the nontraumatic disuse osteoporosis during its active phase. stiffness of cancellous bone in the human patella
E. L. Radin (1975)
The mechanical properties of trabecular microarchitecture during immobilizationinduced lar bone : dependence on anatomical location and funcbone loss
M. B. Schaffler
The relationship between the elasticity menclature , symbols , and units , J . Bone Min . Res . 2 , tensor and the fabric tensor
A. A.M..Drezner.M.K..Glorieux.F.H..Kanis.J.
White anic Prooerties ofBone (Edited bv Cowin. S. C.). DD
B D Snyder
Stereolonic assessment of 'trabecular st&ure in' the lbmbar ve;tebral body Bone mineralassay: its relation to the mechanbiomechanical implications
Asme (1985)
The fabric dependence of the orthotropic L. A
C. H. Turner (1990)
Stiffness behaviour of trabecular bone specimens.
F. Linde (1987)
A comparison between cancellous bone compressive moduli determined from surface strain and total specimen deflection
R. N. Allard (1991)

This paper is referenced by
Analysis of Trabecular Bone Microstructure Using Contour Tree Connectivity
Dogu Baran Aydogan (2013)
Non-invasive bone competence analysis by high-resolution pQCT: an in vitro reproducibility study on structural and mechanical properties at the human radius.
T. L. Mueller (2009)
On the uncertainty quantification and non-linear hyper elastic simulation of biological tissues
Behrouz Shamsaei (2016)
Three-dimensional morphology analysis of vertebral trabecular network architecture using multi-scale method(本文)
Basaruddin Khairul Salleh Bin (2013)
Animal experiment (rabbit) to demonstrate changes in trabecular bone mechanical properties over time using finite element analysis.
Shuo Yang (2006)
Etiology and Pathogenesis of Osteoporosis
Y. An (2002)
Porous calcium aluminate ceramics for bone-graft applications
S. Kalita (2002)
Bone Volume Fraction Explains the Variation in Strength and Stiffness of Cancellous Bone Affected by Metastatic Cancer and Osteoporosis
A. Nazarian (2008)
Scaffold design and manufacturing: from concept to clinic.
S. Hollister (2009)
CHAPTER 2 – The Nature of Osteoporosis
R. Marcus (2008)
Image-based vs. mesh-based statistical appearance models of the human femur: implications for finite element simulations.
S. Bonaretti (2014)
Scaffold translation: barriers between concept and clinic.
S. Hollister (2011)
Image-based computational biomechanics of the musculoskeletal system
E. Chao (2000)
A comparative study of diagnostic and imaging techniques for osteoarthritis of the trapezium.
A. B. Lovati (2015)
Evaluation of MRI resolution affecting trabecular bone parameters: determination of acceptable resolution.
N. Kim (2012)
Mechanical properties of ewe vertebral cancellous bone compared with histomorphometry and high-resolution computed tomography parameters.
D. Mitton (1998)
Comparison of two methods for measuring orientation.
W. Geraets (1998)
Quantitative MRI for the assessment of bone structure and function.
F. Wehrli (2006)
Trabecular bone volume fraction mapping by low-resolution MRI.
M. Fernández-Seara (2001)
The effect of damage on the viscoelastic behavior of human vertebral trabecular bone.
T. Bredbenner (2006)
Mechanical and Microstructural Properties of Polycaprolactone Scaffolds with 1-D , 2-D , and 3-D Orthogonally Oriented Porous Architectures Produced by Selective Laser Sintering
Shaun Eshraghi (2010)
DensiProbe Spine: A Novel Instrument for Intraoperative Measurement of Bone Density in Transpedicular Screw Fixation
Stephan Deckelmann (2010)
Volume to density relation in adult human bone tissue.
Simone Tassani (2011)
Trabecular bone patterning in the hominoid distal femur
Leoni Georgiou (2018)
Porous biodegradable lumbar interbody fusion cage design and fabrication using integrated global-local topology optimization with laser sintering.
Heesuk Kang (2013)
Predicting regional variations in trabecular bone mechanical properties within the human proximal tibia using MR imaging.
S. Lancianese (2008)
Implications of local osteoporosis on the efficacy of anti-resorptive drug treatment: a 3-year follow-up finite element study in risedronate-treated women
D. Anitha (2013)
Quantitative trait loci modulate vertebral morphology and mechanical properties in a population of 18-month-old genetically heterogeneous mice.
G. Reeves (2007)
Characterization of Fracture Resistance in Network-Based Models of Bone
J. Carlson (2018)
Static histomorphometry of human iliac crest and vertebral trabecular bone: a comparative study.
J. Thomsen (2002)
Simulation of osteoporosis bone changes: effects on the degree of anisotropy.
L. Pothuaud (2001)
Mechanical characterization in shear of human femoral cancellous bone: torsion and shear tests.
K. Bruyère Garnier (1999)
See more
Semantic Scholar Logo Some data provided by SemanticScholar