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Basal And Postprandial Lipoprotein Lipase Activity In Adipose Tissue During Caloric Restriction And Refeeding.
M. R. Taskinen, E. Nikkilä
Published 1987 · Biology, Medicine
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The effect of a ten-day caloric restriction period and of subsequent refeeding on adipose tissue lipoprotein lipase (LPL) activity was studied in 14 moderately obese women. The enzyme assays were made from subcutaneous fat taken from three separate regions (gluteal, femoral, and abdominal) after overnight fasting and from one region also after a standard meal. There was a close correlation between the activities measured from the different subcutaneous sites. The caloric restriction was followed by a decrease of the basal LPL activity to one fifth of the value recorded during the isocaloric diet. However, the relative postprandial increase of LPL activity was greater during the low-calorie diet than during the isocaloric diet. During refeeding the basal LPL activity rose but remained at a lower level than before the caloric restriction. The postprandial LPL response was markedly exaggerated after ten days of refeeding (21% increase before dieting and 250% after refeeding). The changes of LPL during caloric restriction and subsequent refeeding were not correlated to plasma insulin levels. The mechanism of the exaggerated LPL response to meal during refeeding remains obscure.
This paper references
Lipoprotein lipase activity in adipose tissue from obese human beings.
W. Dahms (1981)
Effects of prolonged fast on lipoprotein lipase activity eluted from human adipose tissue.
B. Persson (1970)
Lipoprotein Lipase Activity and Uptake of Exogenous Triglycerides in Fat Cells of Different Size
P. Björntorp (1975)
Lipoprotein lipase activity in adipose tissue and in postheparin plasma in human obesity.
M. R. Taskinen (1977)
Effect of fat cell size, restrictive diet and diabetes on lipoprotein lipase release by human adipose tissue.
B. Guy-grand (1975)
Effect of high carbohydrate feeding with dextrose or sucrose on adipose tissue lipoprotein lipase activity and plasma triglyceride levels in hemodialysis patients.
A. Goldberg (1979)
Insulin stimulation of adipose tissue lipoprotein lipase. Use of the euglycemic clamp technique.
C. Sadur (1982)
Effects of caloric restriction on lipid metabolism in man: changes of tissue lipoprotein lipase activities and of serum lipoproteins.
M. R. Taskinen (1979)
Site differences in the basal metabolism of subcutaneous fat in obese women.
P. Arner (1981)
Fat cell metabolism in different regions in women. Effect of menstrual cycle, pregnancy, and lactation.
M. Rebuffe-Scrive (1985)
Lipoprotein-lipase activity in subcutaneous, adipose tissue in healthy subjects: variation of activity in a population of 60-year-old men.
H. Lithell (1978)
Nutritional induction of adipose tissue lipoprotein lipase in obese subjects.
M. Rebuffe-Scrive (1983)
Adipose tissue lipoprotein lipase and weight loss.
R. Schwartz (1984)
Increase of adipose tissue lipoprotein lipase activity with weight loss.
R. Schwartz (1981)
Effects of weight reduction on plasma lipoproteins and adipose tissue metabolism in obese subjects
R. Sorbris (1981)
Use of polyethylene glycol to separate free and antibody-bound peptide hormones in radioimmunoassays.
B. Desbuquois (1971)
Specific determination of blood glucose with o-toluidine.
Aulis Hyvärinen (1962)
Lipoprotein-lipase activity in human skeletal muscle and adipose tissue in the fasting and the fed states.
H. Lithell (1978)
The relationship between the basal lipolytic and lipoprotein lipase activities in human adipose tissue.
P. Arner (1983)
Postprandial adipose tissue lipoprotein lipase activity in primary hypertriglyceridemia.
A. Goldberg (1980)
Effect of fasting on insulin receptor binding and insulin action in different human subcutaneous fat depots.
P. Engfeldt (1985)
Reply to letter by Schwartz and Brunzell
B. Guy-grand (1984)
A micromethod for assay of lipoprotein lipase activity in needle biopsy samples of human adipose tissue and skeletal muscle.
M. R. Taskinen (1980)
INCREASED ADIPOSE-TISSUE LIPOPROTEIN-LIPASE ACTIVITY IN MODERATELY OBESE MEN AFTER WEIGHT REDUCTION
R. Schwartz (1978)
Adipose tissue lipoprotein-lipase activity in obesity.
O. Bosello (1984)
Determinants of human adipose tissue lipoprotein lipase. Effect of diabetes and obesity on basal- and diet-induced activity.
O. Pykälistö (1975)
Insulin and adipose tissue lipoprotein lipase activity in humans.
J. Brunzell (1981)
Characterization of lipase activities in obese Pima indians. Decreases with weight reduction.
J. Reitman (1982)
Lipoprotein lipase of adipose tissue and skeletal muscle in human obesity: response to glucose and to semistarvation.
M. R. Taskinen (1981)
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Acute effects of accumulating exercise on postprandial lipemia and C-reactive protein concentrations in young men.
M. Miyashita (2009)
Resistance exercise and postprandial lipemia: the dose effect of differing volumes of acute resistance exercise bouts
K. Shannon (2005)
Food deprivation increases post‐heparin lipoprotein lipase activity in humans
T. Ruge (2001)
Moderate exercise, postprandial lipemia, and skeletal muscle lipoprotein lipase activity.
S. L. Herd (2001)
Exercise of low energy expenditure along with mild energy intake restriction acutely reduces fasting and postprandial triacylglycerolaemia in young women.
M. Maraki (2009)
Periprandial systemic and regional lipase activity in normal humans.
S. W. Coppack (1996)
Sex-specific differences in leg fat uptake are revealed with a high-fat meal.
S. Votruba (2006)
Glucose and lipid metabolism in insulin resistance : an experimental study in fat cells
Jonas Burén (2003)
The fat cell.
J. Hirsch (1989)
Dietary modification and genetic variability of atherosclerosis risk factors
M. Rantala (2000)
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L. Qiao (2015)
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J. Eriksson (2003)
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V. Pruneta-Deloche (2004)
Effect of a moderate weight loss on adipose tissue lipoprotein lipase activity and expression: existence of sexual variation and regional differences
P. Imbeault (1999)
Étude de facteurs impliqués dans la variation de marqueurs inflammatoires présents dans un contexte d'obésité abdominale et de complications métaboliques associées
Amélie Cartier (2010)
Lipid metabolism in cachectic tumor-bearing rats at different stages of tumor growth.
O. Obeid (1993)
The effects of accumulating physical activity on postprandial lipaemia and other cardiovascular disease risk factors
M. Miyashita (2006)
Sex differences in abdominal, gluteal, and thigh LPL activity.
S. Votruba (2007)
Regulation of lipoprotein lipase activity in the sand rat: effect of nutritional state and cAMP modulation.
T. Chajek-Shaul (1988)
Elevated adipose tissue lipoprotein lipase activity in craniopharyngioma patients.
R. Sorva (1988)
Physiologic basis for the control of body fat distribution in humans.
R. Leibel (1989)
Effects of warm exposure on adipose tissue and muscle metabolism in growing pigs.
D. Rinaldo (1991)
Postprandial lipemia: effects of exercise and restriction of energy intake compared.
J. M. Gill (2000)
Associations of Energy Intake and Type 2 Diabetes with Hypertryglyceridemia in Older Adults Living in the Mediterranean Islands: The Medis Study
S. Tyrovolas (2010)
Impact of Walking on Adipose Tissue Lipoprotein Lipase Activity and Expression in Pre- and Postmenopausal Women
Sébastien Tessier (2010)
Effect of dietary macronutrient composition on tissue-specific lipoprotein lipase activity and insulin action in normal-weight subjects.
T. J. Yost (1998)
Postprandial studies of moderate exercise and triacylglycerol metabolism
J. M. Gill (1999)
Fasting induces ANGPTL4 and reduces LPL activity in human adipose tissue
Philip M M Ruppert (2020)
Regional fat deposition as a factor in FFA metabolism.
S. Votruba (2007)
Maternal High-Fat Feeding Increases Placental Lipoprotein Lipase Activity by Reducing SIRT1 Expression in Mice
L. Qiao (2015)
Effects of energy balance on postprandial triacylglycerol metabolism
Maria I. Maraki (2010)
Tissue‐Specific Responses of Lipoprotein Lipase to Dietary Macronutrient Composition as a Predictor of Weight Gain Over 4 Years
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