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Present And Future Applications Of Biomaterials In Controlled Drug Delivery Systems.

R. Langer, N. Peppas
Published 1981 · Materials Science, Medicine

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Abstract In this paper we review controlled drug release polymeric systems with emphasis on the polymer carriers as biomaterials. Polymer structure affects the diffusion mechanism and release behaviour of various drugs. Zero-order release can be achieved under certain conditions of polymer preparation and for specific geometric shapes. Physical, physicochemical, diffusive and toxicological tests for biomaterials used in controlled release applications are also discussed.
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