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Pain And Tenderness In Human Temporal Muscle Induced By Bradykinin And 5-hydroxytryptamine

K. Jensen, C. Tuxen, U. Pedersen-Bjergaard, I. Jansen, J. Olesen
Published 1990 · Medicine

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Pain was induced in 19 healthy individuals by double-blind injections into the temporal muscle of 0.2 ml of physiological saline with or without active substances added. 5-Hydroxytryptamine (2 nmol) caused pain similar to saline, bradykinin (2 nmol) only insignificantly more pain (0.05 less than p less than 0.1), while a mixture of the two substances in half dosage (1 nmol + 1 nmol) caused pain significantly above saline (p less than 0.01). Variations in the response to saline did not permit a conclusion to be made on the question of induced tenderness. However, the mixture of the two substances appeared to lower the pressure-pain threshold as measured by a pressure algometer (p less than 0.05).
This paper references
10.1093/CVR/10.3.314
An excitatory nociceptive cardiac reflex elicited by bradykinin and potentiated by prostaglandins and myocardial ischaemia.
J. Staszewka-Barczak (1976)
10.1016/0006-8993(74)90870-1
Activation of group IV afferent units from muscle by algesic agents.
S. Mense (1974)
10.1113/jphysiol.1977.sp012088
Thin‐fibre receptors responding to mechanical, chemical, and thermal stimulation in the skeletal muscle of the dog
T. Kumazawa (1977)
10.1002/ANA.410160202
The neurobiology of vascular head pain
M. Moskowitz (1984)
10.1002/cpt19667126
The effect of aspirin on pain and hand blood flow responses to intra‐arterial injection of bradykinin in man
J. Coffman (1966)
10.1111/j.1526-4610.1966.hed0603109.x
VASONEUROACTIVE SUBSTANCES IN MIGRAIN
F. Sicuteri (1966)
10.1097/00006842-195705000-00005
Studies in headache; summary of evidence concerning a noxious agent active locally during migraine headache.
A. Ostfeld (1957)
10.1016/0006-8993(75)90323-6
Muscle receptors with group IV afferent fibres responding to application of bradykinin
M. Franz (1975)
10.1038/NEWBIO240200A0
Prostaglandins, aspirin-like drugs and analgesia.
S. Ferreira (1972)
10.1016/0006-8993(76)90593-X
Excitatory effects of 5-hydroxytryptamine, histamine and potassium ions on muscular group IV afferent units: A comparison with bradykinin
Sibylle Fock (1976)
10.1113/jphysiol.1988.sp017240
Excitation and sensitization of fine articular afferents from cat's knee joint by prostaglandin E2.
H. G. Schaible (1988)
10.1016/0304-3959(89)90239-X
Pressure pain thresholds and thermal nociceptive thresholds in chronic tension-type headache
M. Langemark (1989)
10.1113/jphysiol.1979.sp012615
Effects of mechanical and chemical stimulation of fine muscle afferents upon primate spinothalamic tract cells.
R. Foreman (1979)
10.1111/J.1476-5381.1967.TB02148.X
The disappearance of bradykinin and eledoisin in the circulation and vascular beds of the cat.
S. Ferreira (1967)
10.1016/0304-3959(88)90277-1
Pericranial muscle tenderness and pressure-pain threshold in the temporal region during common migraine
K. Jensen (1988)
10.1113/jphysiol.1982.sp014191
Reduction of the bradykinin‐induced activation of feline group III and IV muscle receptors by acetylsalicylic acid.
S. Mense (1982)
10.1016/0196-9781(90)90142-R
Pain, wheal and flare in human forearm skin induced by bradykinin and 5-hydroxytryptamine
K. Jensen (1990)
10.1152/AJPLEGACY.1965.208.5.867
5-HYDROXYTRYPTAMINE BRADYKININ AND HISTAMINE AS MEDIATORS OF INFLAMMATORY HYPERESTHESIA.
T. M. Gilfoil (1965)
10.1007/BF00592598
Bradykinin and serotonin effects on various types of cutaneous nerve fibres
P. Beck (2004)
10.3181/00379727-126-32489
Bradykinin as a Mediator of Human Pain.∗
T. Kantor (1967)
Visceral pain and the pseudaffective response to intra-arterial injection of bradykinin and other algesic agents.
F. Guzmán (1962)
10.1016/0024-3205(65)90147-5
SEROTONIN--BRADYKININ POTENTIATION ON THE PAIN RECEPTORS IN MAN.
F. Sicuteri (1965)
10.1126/SCIENCE.6087456
Leukotriene B4 produces hyperalgesia that is dependent on polymorphonuclear leukocytes.
J. Levine (1984)
10.1152/AJPHEART.1987.253.3.H556
Hypoxia, bradykinin, and prostaglandins stimulate ischemically sensitive visceral afferents.
J. Longhurst (1987)
10.1016/0003-9969(62)90036-5
Chemical excitants of pain in human dentine and dental pulp.
D. J. Anderson (1962)
10.1002/cpt196784521
Pain and analgesia evaluated by the intraperitoneal bradykinin‐evoked pain method in man
R. Lim (1967)
10.1152/JN.1986.55.2.227
Responses of neurons in feline trigeminal subnucleus caudalis (medullary dorsal horn) to cutaneous, intraoral, and muscle afferent stimuli.
Niichiro Amano (1986)
10.1007/BF00583640
Evidence for the existence of different receptor sites for algesic agents at the endings of muscular group IV afferent units
E. Hiss (2004)
10.1113/jphysiol.1977.sp011802
Nervous outflow from skeletal muscle following chemical noxious stimulation
S. Mense (1977)
10.1016/0304-3959(86)90235-6
Pressure-pain threshold in human temporal region. Evaluation of a new pressure algometer
K. Jensen (1986)
10.1016/0006-8993(81)90320-6
Sensitization of group IV muscle receptors to bradykinin by 5-hydroxytryptamine and prostaglandin E2
S. Mense (1981)
10.1152/AJPLEGACY.1962.203.2.261
Bradykinin and cardiovascular system: estimation of half-life.
K. Saameli (1962)



This paper is referenced by
10.3109/00365513.2010.511257
Interstitial concentration of serotonin is increased in myalgic human trapezius muscle during rest, repetitive work and mental stress – an in vivo microdialysis study
B. Ghafouri (2010)
10.1007/s002210050892
Sensory nerve endings in the hard palate and papilla incisiva of the goat
Z. Halata (1999)
10.1016/S0304-3959(99)00026-3
Experimental human muscle pain and muscular hyperalgesia induced by combinations of serotonin and bradykinin
V. Babenko (1999)
10.1007/S11916-003-0062-9
Central and peripheral sensitization in tension-type headache
L. Bendtsen (2003)
10.1016/j.pain.2007.03.034
Serotonin (5-HT) excites rat masticatory muscle afferent fibers through activation of peripheral 5-HT3 receptors
David W. L. Sung (2008)
10.1007/978-1-4612-1328-4_9
Nitric Oxide, Perivascular Neural Transmission, and Migraine
J. Olesen (2000)
10.1080/03009740600865980
Fundamentals of muscle pain, referred pain, and deep tissue hyperalgesia
T. Graven-Nielsen (2006)
10.1046/j.1468-1331.2003.00570.x
Induction of prolonged tenderness in patients with tension‐type headache by means of a new experimental model of myofascial pain
H. Mørk (2003)
5 HT Increases Excitability of Nociceptor-Like Rat Dorsal Root Ganglion Neurons Via cAMP-Coupled TTX-Resistant Na 1 Channels
L. M. Cárdenas (2001)
10.1177/0333102491011S1128
Experimental Pain in Human Temporal Muscle Induced by Hypertonic Saline, Potassium and Acidity.
K. Jensen (1991)
10.1300/J094v10n01_09
Deep Tissue Hyperalgesia
L. Arendt-Nielsen (2002)
10.1016/S1567-7443(08)10407-0
Effects of Bradykinin on Nociceptors
G. Pethő (2009)
10.1097/00002508-200103000-00002
The Peripheral Apparatus of Muscle Pain: Evidence From Animal and Human Studies
T. Graven-Nielsen (2001)
10.1016/0028-3908(95)00136-0
Activation of 5-HT2A receptors potentiates pain produced by inflammatory mediators
F. Abbott (1996)
10.1113/jphysiol.2002.025106
Contraction‐related factors affect the concentration of a kallidin‐like peptide in rat muscle tissue
F. Boix (2002)
painisometric contraction and their relation to Kinin peptides in human trapezius muscle during
Fernando Boix (2015)
10.1152/JN.2001.86.1.241
5HT increases excitability of nociceptor-like rat dorsal root ganglion neurons via cAMP-coupled TTX-resistant Na(+) channels.
L. Cárdenas (2001)
HEADACHE WITH INHIBITORS OF NITRIC OXDE AND NITRC OXDE SYNTHASE
L. Bendtsen (2017)
Active and passive characteristics of muscle tone and their relationship to models of subluxation/joint dysfunction: Part II
G. A. Knutson (2003)
10.1002/1096-8628(20010108)105:1<110::AID-AJMG1073>3.0.CO;2-#
No evidence for involvement of the human inducible nitric oxide synthase (iNOS) gene in susceptibility to typical migraine.
R. Lea (2001)
10.1007/s004820050179
Neurobiologische Grundlagen von Muskelschmerz
S. Mense (1999)
10.1007/S11916-003-0057-6
The pathogenesis of muscle pain
S. Mense (2003)
10.1016/j.pbb.2006.04.009
Involvement of protein kinase C in 5-HT-evoked thermal hyperalgesia and spinal fos protein expression in the rat
X. Chen (2006)
10.1097/00007632-200107150-00005
Stimulation of Chemosensitive Afferents From Multifidus Muscle Does Not Sensitize Multifidus Muscle Spindles to Vertebral Loads in the Lumbar Spine of the Cat
Y. M. Kang (2001)
10.1097/00002508-200103000-00003
Referred Muscle Pain: Basic and Clinical Findings
L. Arendt-Nielsen (2001)
10.1016/J.APMR.2006.08.339
The effect of zaltoprofen on physiotherapy for limited shoulder movement in breast cancer patients: a single-blinded before-after trial.
K. Hase (2006)
10.1016/S0304-3959(99)00233-X
Pain and allodynia/hyperalgesia induced by intramuscular injection of serotonin in patients with fibromyalgia and healthy individuals
M. Ernberg (2000)
Induction and modulation of referred muscle pain in humans
R. Laursen (1999)
10.1007/s00586-003-0573-4
Calcitonin gene-related peptide immunoreactive neurons with dichotomizing axons projecting to the lumbar muscle and knee in rats
S. Ohtori (2003)
10.1016/j.ijom.2016.01.008
Clinical effects of an avocado-soybean unsaponifiable extract on arthralgia and osteoarthritis of the temporomandibular joint: preliminary study.
I. Catunda (2016)
10.1177/00220345000790101401
Elevated Intramuscular Concentration of Bradykinin in Jaw Muscle Increases the Fusimotor Drive to Neck Muscles in the Cat
F. Hellström (2000)
10.1124/jpet.107.123745
Sensitization and Activation of Intracranial Meningeal Nociceptors by Mast Cell Mediators
Xi-Chun Zhang (2007)
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