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Localized Metabolic Responses To Optokinetic Stimulation In The Brain Stem Nuclei And The Cerebellum Investigated With The [14C]2-deoxyglucose Method In Rats

K. Mori, Y. Miyashita
Published 1989 · Chemistry, Medicine

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The localized metabolic effects of monocular optokinetic stimulation to the cerebellar flocculus and brain stem nuclei were measured in pigmented rats. Quantitative [14C]2-deoxyglucose autoradiography was performed on alert rats stimulated with a drum either rotated horizontally in the temporonasal direction (optokinetic group) or kept stationary (control group). The superior colliculus in both groups showed a higher amount of activity on the contralateral side to the stimulated eye than on the ipsilateral side. The dorsal cap of the inferior olive, the nucleus of the optic tract, and the lateral pontine nucleus showed a higher amount of activity on the contralateral side only in the optokinetic group. The nucleus reticularis tegmenti pontis and the ventromedial aspect of the cerebellar paraflocculus showed no lateralized activity in either group. Local glucose utilization rates of both flocculi were significantly enhanced in the optokinetic group. Only in the optokinetic group did the ipsilateral flocculus show a higher local glucose utilization rate than the contralateral flocculus. The most enhanced activity was localized in the middle aspect of the rostrocaudal extent of the ipsilateral flocculus. The activity was greater in the granular layer than in the molecular layer or in the white matter. The pattern of activation in the granular layer was characterized by a patchy appearance in the frontal sections. Serial reconstruction of these sections showed metabolic blobs appearing with intervals of several hundred micrometers.
This paper references
10.1016/0006-8993(79)90238-5
Descending pathways of the nucleus of the optic tract in the rat
K. Terasawa (1979)
10.1016/0006-8993(85)91261-2
The vermal projection of spinocerebellar tracts arising from lower cervical segments in the cat: an anterograde WGA-HRP study
M. Matsushita (1985)
10.1016/0006-8993(76)90454-6
Adaptation of cat vestibulo-ocular reflex to 200 days of optically reversed vision
G. M. Jones (1976)
10.1111/j.1471-4159.1977.tb10649.x
THE [14C]DEOXYGLUCOSE METHOD FOR THE MEASUREMENT OF LOCAL CEREBRAL GLUCOSE UTILIZATION: THEORY, PROCEDURE, AND NORMAL VALUES IN THE CONSCIOUS AND ANESTHETIZED ALBINO RAT 1
L. Sokoloff (1977)
10.1016/0306-4522(79)90023-X
Visual-vestibular responses in vestibular nuclear neurons in the intact and cerebellectomized, alert cat
E. Keller (1979)
10.1016/0006-8993(75)90376-5
Mossy fiber responses evoked in the cerebellar flocculus of rabbits by stimulation of the optic pathway
K. Maekawa (1975)
10.1152/JN.1971.34.5.920
Discharge characteristics of single units in superior colliculus of the alert rhesus monkey.
P. Schiller (1971)
10.1016/0006-8993(87)90743-8
Cerebral glucose consumption following verbal auditory stimulation
M. Kushner (1987)
10.1002/CNE.902020212
The tectopontine projection in the rat with comments on visual pathways to the basilar pons
R. Burne (1981)
10.1016/S0168-0102(84)80002-4
Analysis of signal content of Purkinje cell responses to optokinetic stimuli in the rabbit cerebellar flocculus by selective lesions of brainstem pathways
Y. Miyashita (1984)
10.1212/WNL.35.1.138
Familial Meige syndrome and thyroid dysfunction
A. Lang (1985)
10.1016/0006-8993(72)90800-1
Climbing fiber activation of Purkinje cells in the flocculus by impulses transferred through the visual pathway.
K. Maekawa (1972)
10.1016/0306-4522(82)90024-0
Topographical representation of vestibulo-ocular reflexes in rabbit cerebellar flocculus
M. Ito (1982)
10.1126/SCIENCE.3603004
Three-dimensional representation and analysis of brain energy metabolism.
L. Hibbard (1987)
10.1152/JN.1979.42.1.1
Tectopontine pathway in the cat: laminar distribution of cells of origin and visual properties of target cells in dorsolateral pontine nucleus.
G. Mower (1979)
10.1016/0306-4522(84)90049-6
The mossy fiber projection of the nucleus reticularis tegmenti pontis to the flocculus and adjacent ventral paraflocculus in the cat
N. Gerrits (1984)
The Cerebellum And Neural Control
M. Ito (1984)
10.1002/CNE.901740304
The parasagittal zonation within the olivocerebellar projection. I. Climbing fiber distribution in the vermis of cat cerebellum
H. Groenewegen (1977)
10.1016/0006-8993(74)90610-6
Visual climbing fiber input to rabbit vestibulo-cerebellum: a source of direction-specific information.
J. Simpson (1974)
10.1159/000123774
Fractured somatotopy in granule cell tactile areas of rat cerebellar hemispheres revealed by micromapping.
G. M. Shambes (1978)
10.1016/0304-3940(77)90079-9
Differential localization of rabbit's flocculus Purkinje cells projecting to the medial and superior vestibular nuclei, investigated by means of the horseradish peroxidase retrograde axonal transport
M. Yamamoto (1977)
10.1016/0304-3940(77)90078-7
Functional localization in the rabbit's cerebellar flocculus determined in relationship with eye movements
M. Dufossè (1977)
10.1016/0006-8993(82)90606-0
Zonal organization of the floccular Purkinje cells projecting to the vestibular nucleus in cats
Y. Sato (1982)
10.1152/JAPPL.1966.21.3.1068
A method for measuring horizontal and vertical eye movement chronically in the monkey.
A. Fuchs (1966)
10.1152/JN.1983.49.3.745
Congruence of spatial organization of tactile projections to granule cell and Purkinje cell layers of cerebellar hemispheres of the albino rat: vertical organization of cerebellar cortex.
J. Bower (1983)
10.1016/0006-8993(74)90344-8
Visual influence on rabbit horizontal vestibulo-ocular reflex presumably effected via the cerebellar flocculus.
M. Ito (1974)
10.1016/0006-8993(81)90881-7
Neural activity of nucleus reticularis tegmenti pontis — the origin of visual mossy fiber afferents to the cerebellar flocculus of rabbits
K. Maekawa (1981)
10.1038/323806A0
Mapping human visual cortex with positron emission tomography
P. Fox (1986)
10.1152/JN.1978.41.3.764
Role of primate flocculus during rapid behavioral modification of vestibuloocular reflex. II. Mossy fiber firing patterns during horizontal head rotation and eye movement.
S. Lisberger (1978)
10.1016/0168-0102(88)90054-5
Metabolic responses of the flocculus to optokinetic stimuli as revealed by the [14C]2-deoxyglucose method in pigmented rats
K. Mori (1988)



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