Online citations, reference lists, and bibliographies.
← Back to Search

Technique For External Beam Treatment For Mesothelioma.

G. Kutcher, C. Kestler, D. Greenblatt, H. Brenner, B. Hilaris, D. Nori
Published 1987 · Medicine

Cite This
Download PDF
Analyze on Scholarcy
A combined photon-electron beam treatment for diffuse pleural mesothelioma is discussed in this paper. The technique consists of parallel opposed 10 MV X rays prescribed to 4250 cGy using customized blocks to shield the lung. The pleura is then boosted with electrons to a dose of 3600 cGy. The combination yields a TDF of 74 ret to the pleura. As discussed in an earlier paper, this treatment method when combined with subtotal pleurectomy and I-125 implantation leads to improved survivals with minimal complications. The details of this 3-dimensional radiation treatment method were not described in detail. To improve target coverage and local control, the technique has been modified. CT is now used along with simulation plane films to define the entire pleural surface. The target volume has also been extended from the dome to the base of this diaphragm. These changes have led to improved pleural dose distributions; by blocking the liver or stomach, and boosting the crus of the diaphragm with electrons, there is little added morbidity. As is demonstrated by dose volume histograms, we have been able to deliver 4250 cGy +/- 10% to most of the pleura with 1/3 of the lung parenchyma receiving less than 2100 cGy.
This paper references

This paper is referenced by
Chemotherapy for malignant pleural mesothelioma: past results and recent developments.
S. Tomek (2004)
Radical pleurectomy/decortication and intraoperative radiotherapy followed by conformal radiation with or without chemotherapy for malignant pleural mesothelioma.
T. T. Lee (2002)
A phase II trial of surgical resection and adjuvant high-dose hemithoracic radiation for malignant pleural mesothelioma.
V. Rusch (2001)
Pleurectomy and decortication for malignant mesothelioma.
S. Cowan (2004)
Patterns of Local and Nodal Failure in Malignant Pleural Mesothelioma After Extrapleural Pneumonectomy and Photon-Electron Radiotherapy
V. Gupta (2009)
Current surgical management of malignant pleural mesothelioma
L. Zellos (2002)
In reply to Drs. Russi et al
K. Rosenzweig (2006)
4.3. Place de la radiothérapie dans le mésothéliome pleural
C. Hennequin (2006)
Compensator‐based intensity‐modulated radiation therapy for malignant pleural mesothelioma post extrapleural pneumonectomy
K. Javedan (2008)
Radiation therapy options for malignant pleural mesothelioma.
E. Baldini (2009)
Evaluation of the photon dose calculation accuracy in radiation therapy of malignant pleural mesothelioma
G. Mahmoudi (2018)
Chapter 8 Mesothelioma : An Evidence-Based Review
J. Goudreault (2013)
A phase II trial of interferon alpha-2a and carboplatin in patients with advanced malignant mesothelioma.
E. O’Reilly (1999)
Investigation of Buildup Dose for Therapeutic Intensity Modulated Photon Beams in Radiation Therapy
K. Javedan (2010)
Promising Early Local Control of Malignant Pleural Mesothelioma Following Postoperative Intensity Modulated Radiotherapy (IMRT) to the Chest
A. Ahamad (2003)
Hemithoracic radiation therapy after pleurectomy/decortication for malignant pleural mesothelioma.
V. Gupta (2005)
Intensity-modulated radiotherapy following extrapleural pneumonectomy for the treatment of malignant mesothelioma: clinical implementation.
K. Forster (2003)
Guidelines for the diagnosis and treatment of malignant pleural mesothelioma.
N. van Zandwijk (2013)
Surgery for malignant pleural mesothelioma
D. Sugarbaker (2010)
Combined photon and electron three-dimensional conformal versus intensity-modulated radiotherapy with integrated boost for adjuvant treatment of malignant pleural mesothelioma after pleuropneumonectomy.
J. Krayenbuehl (2007)
Malignant pleural mesothelioma.
H. Pass (2004)
Proton beam therapy for malignant pleural mesothelioma.
S. Badiyan (2018)
Intensity-modulated photon arc therapy for treatment of pleural mesothelioma.
M. Tobler (2002)
Pleurectomy/decortication plus chemotherapy: outcomes of 40 cases of malignant pleural mesothelioma.
F. Colaut (2004)
Contamination of the pleural surfaces in childhood sarcoma. Use of colloidal P-32 to reduce radiation dose to the whole lung.
J. Montebello (1997)
External beam radiation therapy for the treatment of pleural mesothelioma.
E. Baldini (2004)
Establishing locoregional control of malignant pleural mesothelioma using high‐dose radiotherapy and 18F‐FDG PET/CT scan correlation
M. Feigen (2011)
Lung Cancer and Pleural Mesothelioma
R. Parker (2003)
Intensity-Modulated Radiation Therapy Improves the Target Coverage Over 3-D Planning While Meeting Lung Tolerance Doses for All Patients With Malignant Pleural Mesothelioma
S. Ulger (2017)
Dose-dependent pulmonary toxicity after postoperative intensity-modulated radiotherapy for malignant pleural mesothelioma.
D. Rice (2007)
Pleural irradiation in thoracic malignancies.
J. L. Habrand (1988)
Malignant pleural mesothelioma.
H. Schouwink (1999)
See more
Semantic Scholar Logo Some data provided by SemanticScholar