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Phytochemical And Biological Research Of Polygoneae Medicinal Resources

Da Cheng Hao, Xiao-jie Gu, Pei Gen Xiao
Published 2015 · Biology
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Abstract This chapter synthesizes current knowledge on phytochemistry, bioactivity, molecular phylogeny, and omics of Polygoneae medicinal resources. Many species in the seven genera of Polygoneae are traditional and popular medicinal herbs. Anthraquinones and stilbenes are characteristic medicinal compounds of Polygoneae, while other useful constituents, such as alkaloids, glycosides, flavonoids, volatile oils, tannins, resins, coumarins, and lignans, have also been isolated from Polygoneae species. Among versatile bioactivities of Polygoneae compounds, their effects on the cardiovascular and nervous systems and their anti-inflammatory, antimicrobial, antiparasitic, insecticidal, anticancer, and antioxidant activities are highlighted. Interspecific hybridization and the following polyploidization play a major role in Polygoneae diversification. Nuclear ITS and chloroplast DNA sequences are retrieved to resolve the interspecific relationship and reassign some taxa to the appropriate genus. Omics study of Polygoneae is at the budding stage, which will revolutionize the sustainable utilization of Polygoneae medicinal resources.
This paper references
10.1016/j.jpba.2013.10.037
Simultaneous quantification and peroxynitrite-scavenging activities of flavonoids in Polygonum aviculare L. herb.
Agung Nugroho (2014)
10.1016/j.jep.2013.12.021
Anti-atherosclerotic effects of Polygonum aviculare L. ethanol extract in ApoE knock-out mice fed a Western diet mediated via the MAPK pathway.
Sun Haeng Park (2014)
10.7314/APJCP.2014.15.6.2453
Ginsenoside Rg1 induces apoptosis through inhibition of the EpoR-mediated JAK2/STAT5 signalling pathway in the TF-1/ Epo human leukemia cell line.
Jing Li (2014)
10.1038/aps.2013.100
Yin and Yang of ginseng pharmacology: ginsenosides vs gintonin
Dong-soon Im (2013)
10.1016/j.taap.2014.03.026
Attenuation of Aβ25-35-induced parallel autophagic and apoptotic cell death by gypenoside XVII through the estrogen receptor-dependent activation of Nrf2/ARE pathways.
Xiangbao Meng (2014)
10.3724/SP.J.1009.2012.00028
5, 6-Dihydropyranobenzopyrone: a previously undetermined antioxidant isolated from Polygonum amplexicaule : 5, 6-Dihydropyranobenzopyrone: a previously undetermined antioxidant isolated from Polygonum amplexicaule
A. Tantry Mudasir (2012)
10.3390/nu6020517
Immunomodulatory Activity of Red Ginseng against Influenza A Virus Infection
Jong Seok Lee (2014)
10.1248/CPB.C12-00764
Saponins composition of rhizomes, taproots, and lateral roots of Satsuma-ninjin (Panax japonicus).
Kouichi Yoshizaki (2013)
10.1111/j.1745-7254.2008.00869.x
Botanical characteristics, pharmacological effects and medicinal components of Korean Panax ginseng C A Meyer
Kwang-tae Choi (2008)
10.1074/jbc.M113.482315
The Inhibitory Effects of a Rhamnogalacturonan Ι (RG-I) Domain from Ginseng Pectin on Galectin-3 and Its Structure-Activity Relationship*
Xiaoge Gao (2013)
10.1371/journal.pone.0075034
A Key Role of microRNA-29b for the Suppression of Colon Cancer Cell Migration by American Ginseng
Deepak Poudyal (2013)
10.1055/s-0034-1368319
Isolation and immunosuppressive effects of 6″-O-acetylginsenoside Rb1 extracted from North American ginseng.
Raziye Samimi (2014)
10.1016/j.jgr.2013.11.015
Processed Vietnamese ginseng: Preliminary results in chemistry and biological activity
Thi Hong Van Le (2014)
10.1016/j.lfs.2014.05.010
p38 MAPK and ERK1/2 pathways are involved in the pro-apoptotic effect of notoginsenoside Ft1 on human neuroblastoma SH-SY5Y cells.
Bo Gao (2014)
10.3892/mmr.2014.2328
Anti‑inflammatory effects of Panax notoginseng saponins ameliorate acute lung injury induced by oleic acid and lipopolysaccharide in rats.
Y. K. Chen (2014)
10.1016/j.jep.2014.08.023
Study of the protective mechanisms of Compound Danshen Tablet (Fufang Danshen Pian) against myocardial ischemia/reperfusion injury via the Akt-eNOS signaling pathway in rats.
Qin Ren-an (2014)
10.5142/jgr.2012.36.1.1
Chemical Diversity of Panax ginseng, Panax quinquifolium, and Panax notoginseng
Dong-Hyun Kim (2012)
10.1155/2014/978034
Panaxatriol Saponins Attenuated Oxygen-Glucose Deprivation Injury in PC12 Cells via Activation of PI3K/Akt and Nrf2 Signaling Pathway
Yongliang Huang (2014)
10.1016/j.jep.2013.07.007
A bioactivity-guided study on the anti-diarrheal activity of Polygonum chinense Linn.
Hai-tao Xiao (2013)
10.5740/JAOACINT.12-195
Gas chromatography/mass spectrometry-based metabolic profiling and differentiation of ginseng roots according to cultivation age using variable selection.
Hae Eun Park (2013)
Antiproliferative activity of polygonaceae
I. Lajter (2013)
10.3892/ol.2013.1696
Polydatin inhibits growth of lung cancer cells by inducing apoptosis and causing cell cycle arrest
Yusong Zhang (2014)
10.1016/j.phytochem.2014.07.012
Saponins in the genus Panax L. (Araliaceae): a systematic review of their chemical diversity.
Wen-zhi Yang (2014)
10.1186/1749-8546-9-20
Panax ginseng therapy for chronic obstructive pulmonary disease: a clinical trial protocol and pilot study
Lei Wu (2014)
10.1002/PTR.5103
The antidepressant effects of ginseng total saponins in male C57BL/6N mice by enhancing hippocampal inhibitory phosphorylation of GSK-3β.
Lin Chen (2014)
10.1016/j.bbr.2014.01.039
Resveratrol reverses the effects of chronic unpredictable mild stress on behavior, serum corticosterone levels and BDNF expression in rats
De-xiang Liu (2014)
10.4268/CJCMM20122014
[Active neuraminidase constituents of Polygonum cuspidatum against influenza A(H1N1) influenza virus].
K Chen (2012)
10.1155/2014/351856
Red Ginseng Extract Ameliorates Autoimmune Arthritis via Regulation of STAT3 Pathway, Th17/Treg Balance, and Osteoclastogenesis in Mice and Human
Jooyeon Jhun (2014)
10.1016/j.jep.2009.05.042
Authentication of the family Polygonaceae in Chinese pharmacopoeia by DNA barcoding technique.
Jingyuan Song (2009)
10.3892/BR.2014.263
Tanshinone IIA promotes non-amyloidogenic processing of amyloid precursor protein in platelets via estrogen receptor signaling to phosphatidylinositol 3-kinase/Akt.
Chun Shi (2014)
-tetrahydroxystilbene-2-O-b-D-glucoside (THSG) attenuates human platelet aggregation, secretion and spreading in vitro
K Xiang (1940)
[Analysis of ITS sequences of some medicinal plants and their related species in Salvia].
Ying Wang (2007)
10.1016/j.jep.2014.07.049
Prevention of pulmonary fibrosis with salvianolic acid a by inducing fibroblast cell cycle arrest and promoting apoptosis.
Yongming Pan (2014)
10.1016/j.metabol.2014.06.015
Association of GLP-1 secretion with anti-hyperlipidemic effect of ginsenosides in high-fat diet fed rats.
Can Liu (2014)
Flavonoid glucuronides with
H. D. Smolarz (2008)
10.1002/cbdv.201300233
Chemotype diversity of indigenous Dalmatian sage (Salvia officinalis L.) populations in Montenegro.
Danijela Stešević (2014)
Study on chemical composition of ethylacetate fraction from Polygonum amplexicaule var
M. X. Xiang (2012)
10.1208/s12249-014-0138-3
The Melanogenesis-Inhibitory Effect and the Percutaneous Formulation of Ginsenoside Rb1
Lin Wang (2014)
10.1134/S1022795410080053
Polymorphism of RAPD, ISSR and AFLP markers of the Panax ginseng C. A. Meyer (Araliaceae) genome
Galina D Reunova (2010)
10.1155/2014/179529
Effects of a Proprietary Freeze-Dried Water Extract of Eurycoma longifolia (Physta) and Polygonum minus on Sexual Performance and Well-Being in Men: A Randomized, Double-Blind, Placebo-Controlled Study
Jay K. Udani (2014)
10.1021/np400948n
Manoyloxide Sesterterpenoids from Salvia mirzayanii.
Samad N Ebrahimi (2014)
10.1016/j.fct.2010.08.020
Chemical composition of the essential oil and hexane extract of Salvia chionantha and their antioxidant and anticholinesterase activities.
Gülsen Tel (2010)
10.1371/journal.pone.0046574
Protective Effects of Polydatin from Polygonum cuspidatum against Carbon Tetrachloride-Induced Liver Injury in Mice
Hong Zhang (2012)
10.14233/ajchem.2013.13000
[Chemical constituents from Salvia przewalskii Maxim].
Li-xin Yang (2011)
10.1007/s11095-014-1437-9
Cumulative Organic Anion Transporter-Mediated Drug-Drug Interaction Potential of Multiple Components in Salvia Miltiorrhiza (Danshen) Preparations
Li Wang (2014)
10.1016/j.jash.2014.04.004
Effect of Rg3-enriched Korean red ginseng (Panax ginseng) on arterial stiffness and blood pressure in healthy individuals: a randomized controlled trial.
Elena Jovanovski (2014)
10.1007/s10265-010-0367-9
Phylogenetic relationships among subgenera, species, and varieties of Japanese Salvia L. (Lamiaceae)
Atsuko Takano (2010)
10.1007/s00436-014-4037-z
Effect of Polygonum hydropiper L. against dengue vector mosquito Aedes albopictus L.
Rajan Maheswaran (2014)
10.1021/jf0608773
Chemical composition and antifungal activity of Salvia macrochlamys and Salvia recognita essential oils.
Nurhayat Tabanca (2006)
10.1016/j.fitote.2012.03.006
An unusual taxodione derivative from hairy roots of Salvia austriaca.
Lukasz Kuźma (2012)
10.1021/jf502214x
Quantitative Comparison and Metabolite Profiling of Saponins in Different Parts of the Root of Panax notoginseng
Jing-Rong Wang (2014)
10.1007/s11655-014-1791-1
Antioxidant effect of salvianolic acid B on hippocampal CA1 neurons in mice with cerebral ischemia and reperfusion injury
Yu-feng Jiang (2014)
Resveratrol attenuates oxidative damage
Zhongguo Zhong Yao Za Zhi (2012)
10.1016/j.carbpol.2013.09.038
Polysaccharides from Panax japonicus C.A. Meyer and their antioxidant activities.
Xiaolin Yang (2014)
10.22037/IJPR.2013.1364
Cytotoxic, Antioxidant and Antimicrobial Activities and Phenolic Contents of Eleven Salvia Species from Iran
Omidreza Firuzi (2013)
10.1007/s11064-014-1321-3
Ginsenoside Rd Attenuates Tau Protein Phosphorylation Via the PI3K/AKT/GSK-3β Pathway After Transient Forebrain Ischemia
Xiao Zhang (2014)
10.1016/j.intimp.2014.06.018
Notoginsenoside R1 attenuates amyloid-β-induced damage in neurons by inhibiting reactive oxygen species and modulating MAPK activation.
Bo Ma (2014)
10.1016/j.bmcl.2013.06.098
Promotion effect of constituents from the root of Polygonum multiflorum on hair growth.
Ya Nan Sun (2013)
The effect of 2, 3, 40, 5-tetrahydroxystilbene-2-O-bD-glucoside on pressure overload-induced cardiac remodeling in rats and its possible mechanism
X. L. Xu (2014)
In vitro a-glucosidase inhibitory
Int (2012)
10.1152/ajpheart.00017.2014
Polydatin attenuates cardiac hypertrophy through modulation of cardiac Ca2+ handling and calcineurin-NFAT signaling pathway.
Wenwen Ding (2014)
10.1155/2014/204840
Protective Effects of Panax Notoginseng Saponins on Cardiovascular Diseases: A Comprehensive Overview of Experimental Studies
Xiaochen Yang (2014)
10.1016/j.jep.2014.04.023
Lipid-lowering effects of Danhong injection on hyperlipidemia rats.
Juan Chen (2014)
10.1167/iovs.14-14008
Effect of tanshinone IIA in an in vitro model of Graves' orbitopathy.
Soolienah Rhiu (2014)
10.3967/bes2014.053
Protective effects of ginsenoside Rb1 on septic rats and its mechanism.
Li Wu (2014)
10.1007/s00299-010-0841-9
EST analysis and annotation of transcripts derived from a trichome-specific cDNA library from Salvia fruticosa
Fani Chatzopoulou (2010)
Simultaneous quantification and
A. 753–755. Nugroho (2014)
10.7762/cnr.2014.3.2.89
Effects of Korean White Ginseng (Panax Ginseng C.A. Meyer) on Vascular and Glycemic Health in Type 2 Diabetes: Results of a Randomized, Double Blind, Placebo-controlled, Multiple-crossover, Acute Dose Escalation Trial
Esra' Shishtar (2014)
10.1016/j.jep.2014.07.034
Ginseng treatment reverses obesity and related disorders by inhibiting angiogenesis in female db/db mice.
Hyunghee Lee (2014)
10.1007/BF02969276
A new stilbene glucoside from the roots ofPolygonum multiflorum Thunb.
Minglu Xu (2006)
Apoptosis induction
M. A. e93217. Mohd Ghazali (2014)
10.1021/np500108r
8-Methyltryptanthrin-induced differentiation of P19CL6 embryonal carcinoma cells into spontaneously beating cardiomyocyte-like cells.
Kazuhiko Seya (2014)
10.1093/bioinformatics/btp336
SOAP2: an improved ultrafast tool for short read alignment
Ruiqiang Li (2009)
Botanical DNA evidence
W. J. Koopman (2012)
10.1093/aob/mcu081
Why Africa matters: evolution of Old World Salvia (Lamiaceae) in Africa.
Maria Will (2014)
10.1016/j.fitote.2013.08.026
Antioxidant and anti-inflammatory flavonol glucuronides from Polygonum aviculare L.
Sebastian Granica (2013)
10.3390/molecules19011258
Inhibition of Epstein-Barr Virus Lytic Cycle by an Ethyl Acetate Subfraction Separated from Polygonum cuspidatum Root and Its Major Component, Emodin
Ching-Yi Yiu (2014)
10.3390/ijms141224581
A Simple Strategy for Development of Single Nucleotide Polymorphisms from Non-Model Species and Its Application in Panax
Ming Li (2013)
10.3390/ijms130912082
Development of New Microsatellite Markers for Salvia officinalis L. and Its Potential Use in Conservation-Genetic Studies of Narrow Endemic Salvia brachyodon Vandas
Ivan Radosavljević (2012)
[Study on the chemical constituents of the active fraction of Polygonum capitatum].
Li-juan Zhang (2012)
10.1016/j.pbb.2013.10.007
Antidepressant-like activity of resveratrol treatment in the forced swim test and tail suspension test in mice: The HPA axis, BDNF expression and phosphorylation of ERK
Zhen Wang (2013)
10.3109/13880209.2013.775160
Polyphenols from aerial parts of Polygonum bellardii and their biological activities
Adel Mohamed Abd El-Kader (2013)
10.1007/s12263-012-0319-1
Resveratrol ameliorates high-glucose-induced hyperpermeability mediated by caveolae via VEGF/KDR pathway
Chong Tian (2012)
10.2217/fon.13.276
Protective effect of Panax ginseng in cisplatin-induced cachexia in rats.
Carla Lobina (2014)
10.1111/jipb.12239
Identification of mRNA-like non-coding RNAs and validation of a mighty one named MAR in Panax ginseng.
Meizhen Wang (2015)
10.1371/journal.pone.0078568
Complete Sequencing of Five Araliaceae Chloroplast Genomes and the Phylogenetic Implications
Rong Li (2013)
10.3892/etm.2014.1919
Protective effects of Salvia miltiorrhiza injection against learning and memory impairments in streptozotocin-induced diabetic rats
Huabo Cai (2014)
10.1073/pnas.0805141105
Allopolyploid speciation in Persicaria (Polygonaceae): Insights from a low-copy nuclear region
Sang-Tae Kim (2008)
10.1016/j.fct.2012.09.025
8-Hydroxycalamenene isolated from the rhizomes of Reynoutria elliptica exerts neuroprotective effects both in vitro and in vivo.
Hyoung Jo (2013)
10.1177/1934578X1400900637
Chemical Composition, and Cytotoxic, Antioxidant and Antibacterial Activities of the Essential Oil from Ginseng Leaves
Rui Jiang (2014)
[Research of ginsenosides in kou zi qi using HPLC-MS-MS].
Kun Zou (2004)
10.1016/j.alcohol.2014.06.002
Reducing effect of the Chinese medicinal herb, Salvia miltiorrhiza, on alcohol self-administration in Sardinian alcohol-preferring rats.
Paola Maccioni (2014)
10.1016/j.ympev.2003.10.009
Phylogeny of Panax using chloroplast trnC-trnD intergenic region and the utility of trnC-trnD in interspecific studies of plants.
Chunghee Lee (2004)
10.3892/mmr.2014.2254
Tanshinone IIA reduces the risk of Alzheimer's disease by inhibiting iNOS, MMP‑2 and NF‑κBp65 transcription and translation in the temporal lobes of rat models of Alzheimer's disease.
Ping Jiang (2014)
10.3892/or.2014.3140
Tanshinone IIA blocks epithelial-mesenchymal transition through HIF-1α downregulation, reversing hypoxia-induced chemotherapy resistance in breast cancer cell lines.
Peifen Fu (2014)
10.1080/14786419.2014.939086
In vitro antioxidant and antiproliferative activities of nine Salvia species
Monica Rosa Loizzo (2014)
10.3732/ajb.1100117
Development and characterization of microsatellite markers for Panax notoginseng (Araliaceae), a Chinese traditional herb.
Han Liu (2011)
10.1016/j.carbpol.2014.04.061
A polysaccharide from Salvia miltiorrhiza Bunge improves immune function in gastric cancer rats.
Nan Wang (2014)
10.4103/2225-4110.114905
Anti-inflammatory Activity of the Invasive Neophyte Polygonum Cuspidatum Sieb. and Zucc. (Polygonaceae) and the Chemical Comparison of the Invasive and Native Varieties with regard to Resveratrol
Peihong Fan (2013)
10.1021/np3001464
Neo-clerodane diterpenes from Salvia herbacea.
Elihú Bautista (2012)
10.1155/2013/680545
Tetrahydroxystilbene Glucoside Attenuates Neuroinflammation through the Inhibition of Microglia Activation
F. H. Zhang (2013)
10.1080/10286020.2013.837454
Five new stilbene glycosides from the roots of Polygonum multiflorum
Shuo-Guo Li (2013)
10.1016/j.jep.2014.05.008
The haematopoietic effect of Panax japonicus on blood deficiency model mice.
Hong Zhang (2014)
10.1016/j.phymed.2013.09.021
Genuine traditional Korean medicine, Naju Jjok (Chung-Dae, Polygonum tinctorium) improves 2,4-dinitrofluorobenzene-induced atopic dermatitis-like lesional skin.
Na-ra Han (2014)
10.1159/000362999
Salvianolic Acid B Inhibited PPARγ Expression and Attenuated Weight Gain in Mice with High-Fat Diet-Induced Obesity
Peijian Wang (2014)
10.1055/s-0032-1328063
Abietane diterpenoids from Salvia sahendica--antiprotozoal activity and determination of their absolute configurations.
Samad N Ebrahimi (2013)
10.1248/BPB.B14-00301
Tanshinone IIA induces apoptosis in fibroblast-like synoviocytes in rheumatoid arthritis via blockade of the cell cycle in the G2/M phase and a mitochondrial pathway.
Ligang Jie (2014)
10.1016/j.phymed.2014.06.013
Reversal of P-glycoprotein (P-gp) mediated multidrug resistance in colon cancer cells by cryptotanshinone and dihydrotanshinone of Salvia miltiorrhiza.
Tao Hu (2014)
10.3732/ajb.1000462
New microsatellite markers for Salvia officinalis (Lamiaceae) and cross-amplification in closely related species.
Ivan Radosavljević (2011)
10.1371/journal.pone.0078700
Resveratrol Inhibits Invasion and Metastasis of Colorectal Cancer Cells via MALAT1 Mediated Wnt/β-Catenin Signal Pathway
Qing Ji (2013)
10.1016/j.ejphar.2014.04.045
Protocatechualdehyde prevents methylglyoxal-induced mitochondrial dysfunction and AGEs-RAGE axis activation in human lens epithelial cells.
Yue-Hua Wang (2014)
Polygonum viviparum L.
Harold C. Fritts (1956)
10.1371/journal.pone.0093217
Genetic Diversity and Population Structure in Polygonum cespitosum: Insights to an Ongoing Plant Invasion
Silvia Matesanz (2014)
10.3390/ijms13032692
Flavonoid Biosynthesis Genes Putatively Identified in the Aromatic Plant Polygonum minus via Expressed Sequences Tag (EST) Analysis
Nur Diyana Roslan (2012)
10.1111/and.12255
Dose-dependent effects of ethanol extract of Salvia haematodes Wall roots on reproductive function and copulatory behaviour in male rats.
Falgun Wanganuji Bansode (2015)
10.1248/CPB.C12-00794
Four new triterpenoid saponins from the leaves of Panax japonicus grown in southern Miyazaki Prefecture (4).
Kouichi Yoshizaki (2013)
10.1155/2012/404012
Gastroprotective Activity of Polygonum chinense Aqueous Leaf Extract on Ethanol-Induced Hemorrhagic Mucosal Lesions in Rats
Iza Farhana Ismail (2012)
10.1155/2014/450572
Synergistic Effect between Cryptotanshinone and Antibiotics against Clinic Methicillin and Vancomycin-Resistant Staphylococcus aureus
Jeong-Dan Cha (2014)
10.1007/s11064-014-1312-4
Anti-inflammatory Effect of Tanshinone I in Neuroprotection Against Cerebral Ischemia–Reperfusion Injury in the Gerbil Hippocampus
Joon Ha Park (2014)
10.3969/J.ISSN.1674-6348.2013.03.001
Pharmacophylogenetic Study on Plants of Genus Salvia L. from China
Minhui Li (2013)
10.1016/j.phrs.2014.08.001
Resveratrol and cardiovascular health--promising therapeutic or hopeless illusion?
Philip Chiu-Tsun Tang (2014)
10.1371/journal.pone.0061261
Age Estimates for the Buckwheat Family Polygonaceae Based on Sequence Data Calibrated by Fossils and with a Focus on the Amphi-Pacific Muehlenbeckia
Tanja M. Schuster (2013)
10.1111/1750-3841.12205
Reduction of hepatitis A virus on FRhK-4 cells treated with Korean red ginseng extract and ginsenosides.
Min Hwa Lee (2013)
10.1055/s-0031-1280454
Diterpenoids including a novel dimeric conjugate from Salvia leriaefolia.
Mohammad Iqbal Choudhary (2012)
10.1016/j.phytochem.2014.07.001
Cytotoxic diterpenoids from Salvia yunnanensis.
Chun-yan Wu (2014)
10.3892/ijmm.2013.1519
Biochemical basis of cancer chemoprevention and/or chemotherapy with ginsenosides (Review).
Joon-Seok Choi (2013)
10.1016/j.thromres.2013.11.006
2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside (THSG) attenuates human platelet aggregation, secretion and spreading in vitro.
Ke Xiang (2014)
10.1039/c4fo00305e
Piceid presents antiproliferative effects in intestinal epithelial Caco-2 cells, effects unrelated to resveratrol release.
Carolina E Storniolo (2014)
10.1111/bph.12804
Emodin inhibits tonic tension through suppressing PKCδ-mediated inhibition of myosin phosphatase in rat isolated thoracic aorta.
Kyung-Min Lim (2014)
10.1177/1934578X1200700601
Distribution of Drimane Sesquiterpenoids and Tocopherols in Liverworts, Ferns and Higher Plants: Polygonaceae, Canellaceae and Winteraceae Species
Yoshinori Asakawa (2012)
10.1080/14786419.2010.541884
A new triterpene from Salvia xanthocheila Boiss.
Somayyeh Gandomkar (2012)
10.3892/mmr.2014.1943
Hexane extracts of Polygonum multiflorum improve tissue and functional outcome following focal cerebral ischemia in mice.
Soo Vin Lee (2014)
10.1002/ddr.21214
Network pharmacology: a Rosetta Stone for traditional Chinese medicine.
Da Cheng Hao (2014)
10.1016/j.toxlet.2014.04.011
Salvianolic acid B protects against acute ethanol-induced liver injury through SIRT1-mediated deacetylation of p53 in rats.
Mingzhu Li (2014)
Purification, antioxidant activity
Y. Cheng (2014)
10.1142/S0192415X14500517
Notoginsenoside R1 attenuates hypoxia and hypercapnia-induced vasoconstriction in isolated rat pulmonary arterial rings by reducing the expression of ERK.
Yixiao Xu (2014)
10.1159/000365784
Compound Astragalus and Salvia miltiorrhiza Extract Suppresses Rabbits' Hypertrophic Scar by Modulating the TGF-β/Smad Signal
Chao Wu (2014)
10.1016/j.gene.2014.05.021
Protective effect of Salvia miltiorrhiza aqueous extract on myocardium oxidative injury in ischemic-reperfusion rats.
Guanghao Ge (2014)
10.3390/molecules181011842
In Vitro and in Vivo Studies of the Inhibitory Effects of Emodin Isolated from Polygonum cuspidatum on Coxsakievirus B4
Zhao Liu (2013)
10.3390/ijms15069859
Ginsenoside Rd Attenuates Mitochondrial Permeability Transition and Cytochrome c Release in Isolated Spinal Cord Mitochondria: Involvement of Kinase-Mediated Pathways
Jin-song Zhou (2014)
10.1055/s-0030-1250166
DNA barcoding of Panax species.
Yunjuan Zuo (2011)
10.1016/j.transproceed.2013.12.028
Ginsenoside Rg3 enhances islet cell function and attenuates apoptosis in mouse islets.
S S Kim (2014)
10.1016/j.neuint.2014.06.001
Neuroprotection against Aβ25–35-induced apoptosis by Salvia miltiorrhiza extract in SH-SY5Y cells
Hui-min Yu (2014)
10.1016/j.carbpol.2014.02.035
Antioxidant activities of the oligosaccharides from the roots, flowers and leaves of Panax ginseng C.A. Meyer.
Lili Jiao (2014)
10.1016/j.carbpol.2013.09.007
Purification, antioxidant activity and antiglycation of polysaccharides from Polygonum multiflorum Thunb.
Lishuang Lv (2014)
10.1186/1472-6882-13-51
In vitro biological effects of two anti-diabetic medicinal plants used in Benin as folk medicine
Fifa T. D. Bothon (2013)
10.1021/cr200058f
Constituents from Salvia species and their biological activities.
Yi-Bing Wu (2012)
10.1016/j.bmcl.2014.07.042
Triterpene glycosides from red ginseng marc and their anti-inflammatory activities.
Ill-Min Chung (2014)
10.3390/molecules18022255
Characterization of Proanthocyanidins in Stems of Polygonum multiflorum Thunb as Strong Starch Hydrolase Inhibitors
Hongyu Wang (2013)
10.1093/aob/mcl176
Staminal evolution in the genus Salvia (Lamiaceae): molecular phylogenetic evidence for multiple origins of the staminal lever.
Jay B. Walker (2007)
10.1016/j.ympev.2013.08.018
Molecular phylogeny of Koenigia L. (Polygonaceae: Persicarieae): implications for classification, character evolution and biogeography.
Deng-Mei Fan (2013)
10.1016/j.sjbs.2010.12.010
Studies on genetic diversity among populations of Persicaria barbata (L.) H. Hara from India based on internal transcribed spacer sequences of nuclear ribosomal DNA.
Ritesh Kumar Choudhary (2011)
Small-molecule STAT3 signaling pathway
J. Liu (2012)
10.1016/S1875-5364(12)60006-5
5, 6-Dihydropyranobenzopyrone: a previously undetermined antioxidant isolated from Polygonum amplexicaule.
Mudasir Ahmad Tantry (2012)
10.1371/journal.pone.0103229
Inhibitory Effect of Tanshinone IIA on Rat Hepatic Stellate Cells
Ya-Wei Liu (2014)
10.3892/ijmm.2013.1548
Inhibition of IL-32 and TSLP production through the attenuation of caspase-1 activation in an animal model of allergic rhinitis by Naju Jjok (Polygonum tinctorium).
Hyun-Ja Jeong (2014)
Polygonum cuspidatum inhibits pancreatic
Y. S. Kim (2013)
10.1016/j.jep.2014.04.037
Panax notoginseng saponins (PNS) inhibits breast cancer metastasis.
Peiwei Wang (2014)
10.1016/j.bmc.2013.11.002
Dammarane triterpenes from the leaves of Panax ginseng enhance cellular immunity.
Tien-Lam Tran (2014)
10.1007/s11655-014-1881-8
Effects of Panax Quinquefolium Saponin on phosphatidylinositol 3-kinase/serine threonine kinase pathway of neonatal rat myocardial cells subjected to hypoxia
Chun-yu Guo (2014)
8-Methyltryptanthrin-induced differentiation
K. e61261. Seya (2014)
10.1186/1471-2164-15-S2-P73
Analysis of chromosomal and genetic disorders in patients with recurrent miscarriages in Saudi Arabia
Rola F. Turki (2014)
10.1517/13543784.2014.892582
Saponins of Panax notoginseng: chemistry, cellular targets and therapeutic opportunities in cardiovascular diseases
Jingjing Liu (2014)
10.1016/j.jpba.2014.04.032
Discrimination of leaves of Panax ginseng and P. quinquefolius by ultra high performance liquid chromatography quadrupole/time-of-flight mass spectrometry based metabolomics approach.
Qian Jing Mao (2014)
10.1016/j.fitote.2012.05.005
Norditerpenoids from Salvia castanea Diels f. pubescens.
Zheng-hong Pan (2012)
10.1155/2014/540516
Tanshinone IIA Induces Apoptosis in Human Oral Cancer KB Cells through a Mitochondria-Dependent Pathway
Pao-Yu Tseng (2014)
10.1055/s-2004-827192
Comparative study on triterpene saponins of Ginseng drugs.
Shu Gao Zhu (2004)
10.1055/s-2003-40632
Authentication of Panax notoginseng by 5S-rRNA spacer domain and random amplified polymorphic DNA (RAPD) analysis.
X M Cui (2003)
10.1155/2014/969168
American Ginseng Extract (Panax quinquefolius L.) Is Safe in Long-Term Use in Type 2 Diabetic Patients
Iva Mucalo (2014)
10.1177/1934578X1200700616
Cinnamoylphenethyl Amides from Polygonum hyrcanicum Possess Anti-Trypanosomal Activity
Fahimeh Moradi-Afrapoli (2012)
10.2174/0929867053363397
Chemistry and biological activities of caffeic acid derivatives from Salvia miltiorrhiza.
R W Jiang (2005)
10.1021/ol3035033
Polyflavanostilbene A, a new flavanol-fused stilbene glycoside from Polygonum cuspidatum.
Fushuang Li (2013)
10.1155/2013/208349
A Review of the Pharmacological Effects of the Dried Root of Polygonum cuspidatum (Hu Zhang) and Its Constituents
Huan Huan Zhang (2013)
10.1186/1471-2164-14-564
The root transcriptome for North American ginseng assembled and profiled across seasonal development
Di Wu (2013)
10.1016/j.fitote.2014.02.003
Four new eudesmane-type sesquiterpenes from the basal leaves of Salvia plebeia R. Br.
Yiqun Dai (2014)
10.1055/s-0030-1270933
Antiplasmodial and antitrypanosomal activity of tanshinone-type diterpenoids from Salvia miltiorrhiza.
Sylwester Ślusarczyk (2011)
10.1016/j.gene.2013.07.097
A fast SNP identification and analysis of intraspecific variation in the medicinal Panax species based on DNA barcoding.
Xiao-chen Chen (2013)
10.1371/journal.pone.0057607
The Complete Chloroplast Genome Sequence of the Medicinal Plant Salvia miltiorrhiza
Jun Qian (2013)
10.1007/s00253-014-5890-5
Tanshinones extend chronological lifespan in budding yeast Saccharomyces cerevisiae
Ziyun Wu (2014)
10.3732/ajb.91.7.1115
Salvia (Lamiaceae) is not monophyletic: implications for the systematics, radiation, and ecological specializations of Salvia and tribe Mentheae.
Jay B. Walker (2004)
10.1002/cbdv.201300408
Essential-oil diversity of Salvia tomentosa Mill. in Greece.
Effie Hanlidou (2014)
10.1055/s-0033-1351016
Inhibition of G protein-activated inwardly rectifying K+ channels by extracts of Polygonum persicaria and isolation of new flavonoids from the chloroform extract of the herb.
Ildikó Lajter (2013)
10.3727/096368914X678391
Salvianolic Acid B Maintained Stem Cell Pluripotency and Increased Proliferation Rate by Activating Jak2–Stat3 Combined with EGFR–Erk1/2 Pathways
Chia Hui Liu (2014)
10.1007/s12272-014-0344-2
Quercetin-3-O-β-d-glucuronide isolated from Polygonum aviculare inhibits cellular senescence in human primary cells
Hyo Hyun Yang (2014)
10.1080/10286020.2013.794416
Two novel dammarane-type compounds from the leaves and stems of Panax quinquefolium L.
Jin-ping Liu (2013)
10.1002/med.20077
New developments in the chemistry and biology of the bioactive constituents of Tanshen.
Xihong Wang (2007)
10.1021/np4008798
Tyrosinase Inhibitory Activity of a Glucosylated Hydroxystilbene in Mouse Melan-a Melanocytes
Florence Wing-ki Cheung (2014)
10.1055/s-0034-1382877
Prevention of experimental postoperative peritoneal adhesions through the intraperitoneal administration of tanshinone IIA.
Chengxi Wang (2014)
10.1186/1471-2164-11-262
De novo sequencing and analysis of the American ginseng root transcriptome using a GS FLX Titanium platform to discover putative genes involved in ginsenoside biosynthesis
Chao Sun (2009)
10.4268/CJCMM20101201
[Genetic diversity of Polygonum capitatum from Guizhou populations by ISSR markers].
Tao Zhou (2010)
10.1016/j.ijbiomac.2014.01.039
Anti-tumour and immunomodulatory activities of oligosaccharides isolated from Panax ginseng C.A. Meyer.
Li-li Jiao (2014)
10.18632/ONCOTARGET.2034
20(S)-Ginsenoside Rg3 is a novel inhibitor of autophagy and sensitizes hepatocellular carcinoma to doxorubicin
Dong-gun Kim (2014)
10.1016/j.jep.2014.04.047
Induction of liver cytochrome P450s by Danshen-Gegen formula is the leading cause for its pharmacokinetic interactions with warfarin.
Zhen Zhang (2014)
10.1002/jnr.23397
Ginsenoside Rd ameliorates experimental autoimmune encephalomyelitis in C57BL/6 mice.
Dongliang Zhu (2014)
10.3892/ijmm.2014.1750
Antiviral activity of ginseng extract against respiratory syncytial virus infection
Jong Seok Lee (2014)
10.3732/ajb.0700008
Incongruence between cpDNA and nrITS trees indicates extensive hybridization within Eupersicaria (Polygonaceae).
Sang-Tae Kim (2008)
10.1007/s13277-013-1025-3
A potential antitumor ellagitannin, davidiin, inhibited hepatocellular tumor growth by targeting EZH2
Yan Wang (2013)
10.1186/s12967-014-0236-8
Extracts from Salvia-Nelumbinis naturalis alleviate hepatosteatosis via improving hepatic insulin sensitivity
Li Zhang (2014)
10.1111/ppl.12193
Transcriptional data mining of Salvia miltiorrhiza in response to methyl jasmonate to examine the mechanism of bioactive compound biosynthesis and regulation.
Hongmei Luo (2014)
10.1016/S1875-5364(14)60066-2
In vitro anti-leishmanial activity of methanolic extracts of Calendula officinalis flowers, Datura stramonium seeds, and Salvia officinalis leaves.
Banafsheh Nikmehr (2014)
10.12980/APJTB.4.2014C1255
A recent review on phytochemical constituents and medicinal properties of kesum (Polygonum minus Huds.).
Paritala Vikram (2014)
Screening of biological activities of PolygonummaritimumL
I. A. El-Haci (2013)
10.1016/J.APSB.2013.06.001
An ethnopharmacological investigation of medicinal Salvia plants (Lamiaceae) in China
Minhui Li (2013)
10.4103/0973-1296.111266
Xanthone and lignan glycosides from the aerial parts of Polygonum bellardii all growing in Egypt
Adel Mohamed Abd El-Kader (2013)
10.1016/j.bmcl.2010.09.074
Oleanane-type triterpenoids from Panax stipuleanatus and their anticancer activities.
Chun Liang (2010)
10.1155/2009/617509
Genome-Wide Transcriptional Profiling of the Response of Staphylococcus aureus to Cryptotanshinone
Haihua Feng (2009)
10.1016/j.ijbiomac.2014.06.036
Characterization, antioxidant and antitumor activities of polysaccharides from Salvia miltiorrhiza Bunge.
Yuan-yuan Jiang (2014)
10.1016/j.chroma.2014.04.007
Phytochemical profile and nutraceutical potential of chia seeds (Salvia hispanica L.) by ultra high performance liquid chromatography.
Oliviert Martínez-Cruz (2014)
10.1016/j.jep.2014.07.009
Treatment with ginseng total saponins improves the neurorestoration of rat after traumatic brain injury.
Bao-Ying Hu (2014)
10.1371/journal.pone.0099314
Complex Interplay among DNA Modification, Noncoding RNA Expression and Protein-Coding RNA Expression in Salvia miltiorrhiza Chloroplast Genome
Haimei Chen (2014)
10.1093/molbev/mst197
MEGA6: Molecular Evolutionary Genetics Analysis version 6.0.
Koichiro Tamura (2013)
10.1016/j.jgr.2013.11.017
Practical application of DNA markers for high-throughput authentication of Panax ginseng and Panax quinquefolius from commercial ginseng products
Juyeon Jung (2014)
10.1021/jf803320d
Detection of adulteration of notoginseng root extract with other panax species by quantitative HPLC coupled with PCA.
Chong-zhi Wang (2009)
10.4238/2014.July.25.19
CYP1A2 polymorphism in Chinese patients with acute liver injury induced by Polygonum multiflorum.
Kui-fen Ma (2014)
10.1248/BPB.B13-00770
Panax notoginseng saponins promotes stroke recovery by influencing expression of Nogo-A, NgR and p75NGF, in vitro and in vivo.
Lixing Liu (2014)
10.1155/2014/272101
Magnesium Lithospermate B, an Active Extract of Salvia miltiorrhiza, Mediates sGC/cGMP/PKG Translocation in Experimental Vasospasm
Chih-Zen Chang (2014)
10.1186/2008-2231-20-37
In vitro α-glucosidase inhibitory activity of phenolic constituents from aerial parts of Polygonum hyrcanicum
Fahimeh Moradi-Afrapoli (2012)
10.5142/jgr.2012.36.3.298
EST-SSR Marker Sets for Practical Authentication of All Nine Registered Ginseng Cultivars in Korea
Nam-Hoon Kim (2012)
10.1142/S0192415X1450061X
Salvia plebeia suppresses atopic dermatitis-like skin lesions.
Jin Kyeong Choi (2014)
10.1186/1472-6882-14-161
In vitro and ex-vivo cellular antioxidant protection and cognitive enhancing effects of an extract of Polygonum minus Huds (Lineminus™) demonstrated in a Barnes Maze animal model for memory and learning
Annie George (2014)
10.1007/s12013-014-0119-x
Protective Mechanism of Panax notoginseng Saponins on Rat Hemorrhagic Shock Model in Recovery Stage
Huai-Zheng Liu (2014)
10.1111/jphp.12291
Protective effect of saponins extract from Panax japonicus on myocardial infarction: involvement of NF-κB, Sirt1 and mitogen-activated protein kinase signalling pathways and inhibition of inflammation.
Na Wei (2014)
10.1016/j.jep.2014.07.058
Salvia miltiorrhiza: an ancient Chinese herbal medicine as a source for anti-osteoporotic drugs.
Yubo Guo (2014)
6-Dihydropyranobenzopyrone: a previously undetermined antioxidant isolated from Polygonum amplexicaule. Chin
M A Tantry (2012)
10.1016/j.gene.2014.05.024
Transcript expression profiling for adventitious roots of Panax ginseng Meyer.
Sathiyamoorthy Subramaniyam (2014)
10.1007/s11033-012-2286-4
Transcriptome profiling of genes induced by salicylic acid and methyl jasmonate in Polygonum minus
Su-Fang Ee (2012)
10.1016/S2221-1691(13)60124-0
Screening of biological activities of Polygonum maritimum L. from Algerian coast.
Imad Abdelhamid El-Haci (2013)
2008a,b) 107 Diisobutyl phthalate
Kim (2008)
10.3390/ijms15057827
Treatment with Panax Ginseng Antagonizes the Estrogen Decline in Ovariectomized Mice
Y Xu (2014)
10.1248/BPB.B14-00441
Anti-inflammatory effect of ginsenoside Rb1 contributes to the recovery of gastrointestinal motility in the rat model of postoperative ileus.
Shanjun Tan (2014)
10.1080/14786419.2012.673605
A new abietane diterpenoid from Salvia xanthocheila Boiss.
Zohreh Habibi (2013)
10.1016/j.phymed.2012.07.016
Antimicrobial and anti-biofilm properties of new taxodione derivative from hairy roots of Salvia austriaca.
L Kuźma (2012)
10.1016/j.lfs.2012.08.033
Resveratrol attenuates oxidative damage and ameliorates cognitive impairment in the brain of senescence-accelerated mice.
Gui-shan Liu (2012)
10.1016/j.ejphar.2012.05.045
Protective effect of tetrahydroxystilbene glucoside against hydrogen peroxide-induced dysfunction and oxidative stress in osteoblastic MC3T3-E1 cells.
Jin-Kang Zhang (2012)
10.1186/1471-2164-15-277
Genome-wide characterization and comparative analysis of R2R3-MYB transcription factors shows the complexity of MYB-associated regulatory networks in Salvia miltiorrhiza
Caili Li (2013)
10.1016/j.jep.2014.03.042
In vitro effects of active components of Polygonum Multiflorum Radix on enzymes involved in the lipid metabolism.
Wangen Wang (2014)
10.3390/ijms150813209
Chikusetsu Saponin V Attenuates MPP+-Induced Neurotoxicity in SH-SY5Y Cells via Regulation of Sirt1/Mn-SOD and GRP78/Caspase-12 Pathways
Ding Yuan (2014)
10.1002/phar.1473
Influence of Panax ginseng on the steady state pharmacokinetic profile of lopinavir-ritonavir in healthy volunteers.
Mónica M Calderón (2014)
10.1002/jsfa.5795
Polygonum viviparum L. inhibits the lipopolysaccharide-induced inflammatory response in RAW264.7 macrophages through haem oxygenase-1 induction and activation of the Nrf2 pathway.
Hui-wen Cheng (2013)
10.1007/s11655-014-1821-7
Inhibitory effects of 2,3,4′,5-tetrahydroxystilbene-2-O-β-D-glucoside on angiotensin II-induced proliferation of vascular smooth muscle cells
Xiaole Xu (2014)
10.1371/journal.pone.0068480
Protective Effect of Polygonum orientale L. Extracts against Clavibater michiganense subsp. sepedonicum, the Causal Agent of Bacterial Ring Rot of Potato
Jin Hua Cai (2013)
10.1186/1472-6882-14-265
Effects of Korean red ginseng (Panax Ginseng Meyer) on bisphenol A exposure and gynecologic complaints: single blind, randomized clinical trial of efficacy and safety
M. H. Yang (2014)
10.1016/j.fitote.2014.05.021
Inhibitory effect of a novel combination of Salvia hispanica (chia) seed and Punica granatum (pomegranate) fruit extracts on melanin production.
Ganesh Diwakar (2014)
10.1371/journal.pone.0087693
De Novo Assembly and Annotation of Salvia splendens Transcriptome Using the Illumina Platform
Xiuxiu Ge (2014)
activity of phenolic constituents from aerial parts ofPolygonum hyrcanicum
F. Moradi-Afrapoli (2012)
10.1016/j.jep.2013.03.013
Stilbene glucoside inhibits the glucuronidation of emodin in rats through the down-regulation of UDP-glucuronosyltransferases 1A8: application to a drug-drug interaction study in Radix Polygoni Multiflori.
Jiang Ma (2013)
10.1080/14786419.2011.635345
A lupane triterpenoid and other constituents of Salvia eremophila
Mahdi M Farimani (2012)
10.1021/ol202953b
Hydrangenone, a new isoprenoid with an unprecedented skeleton from Salvia hydrangea.
Mahdi M Farimani (2012)
10.1186/1472-6882-14-150
Polygonum viviparum L. induces vasorelaxation in the rat thoracic aorta via activation of nitric oxide synthase in endothelial cells
Ming-Long Chang (2014)
10.1021/np400720y
Polygonumosides A-D, stilbene derivatives from processed roots of Polygonum multiflorum.
Shi-Lun Yan (2014)
10.1371/journal.pone.0103628
Ginsenoside Rb3 Protects Cardiomyocytes against Ischemia-Reperfusion Injury via the Inhibition of JNK-Mediated NF-κB Pathway: A Mouse Cardiomyocyte Model
Lijia Ma (2014)
10.1016/j.phymed.2014.05.003
Salvianolic acid A, a matrix metalloproteinase-9 inhibitor of Salvia miltiorrhiza, attenuates aortic aneurysm formation in apolipoprotein E-deficient mice.
Tingting Christina Zhang (2014)
10.1055/s-0033-1360198
The effect of 2,3,4',5-tetrahydroxystilbene-2-O-β-D-glucoside on pressure overload-induced cardiac remodeling in rats and its possible mechanism.
Xiao Le Xu (2014)
10.4268/cjcmm20140733
[Prescription parsing of miao medicine Polygonum capitatum and kelintong capsule].
Nan Hu (2014)
10.1080/09168451.2014.890032
Content of resveratrol and glycoside and its contribution to the antioxidative capacity of Polygonum cuspidatum (Itadori) harvested in Kochi
Serika Kurita (2014)
10.1371/journal.pone.0029678
Metabolic Profiles and cDNA-AFLP Analysis of Salvia miltiorrhiza and Salvia castanea Diel f. tomentosa Stib
Dongfeng Yang (2012)
10.5142/jgr.2013.37.74
Oleanane-triterpenoids from Panax stipuleanatus inhibit NF-κB
Chun Liang (2013)
10.1007/s12272-014-0435-0
Inhibitory effects of (−)-loliolide on cellular senescence in human dermal fibroblasts
Hyo Hyun Yang (2015)
10.1248/BPB.B13-00921
Danshensu inhibits β-adrenergic receptors-mediated cardiac fibrosis by ROS/p38 MAPK axis.
Haiyan Helen Lu (2014)
10.3390/molecules181012548
Hypolipidemic and Antioxidant Properties of Phenolic Compound-Rich Extracts from White Ginseng (Panax ginseng) in Cholesterol-Fed Rabbits
Lan-Sook Lee (2013)
10.1128/CVI.00127-14
Rapeseed Oil and Ginseng Saponins Work Synergistically To Enhance Th1 and Th2 Immune Responses Induced by the Foot-and-Mouth Disease Vaccine
Cenrong Zhang (2014)
10.1007/s11427-012-4319-6
De novo characterization of the root transcriptome of a traditional Chinese medicinal plant Polygonum cuspidatum
Da-Cheng Hao (2012)
10.1016/j.biopha.2012.10.007
Proteomic analysis for anti-atherosclerotic effect of tetrahydroxystilbene glucoside in rats.
Wenjuan Yao (2013)
10.1186/1472-6882-14-99
Fusarium inhibition by wild populations of the medicinal plant Salvia africana-lutea L. linked to metabolomic profiling
Mpumelelo Nkomo (2014)
10.4103/0973-1296.133271
Inhibitory effects of ginseng seed on melanin biosynthesis
Yeonmi Lee (2014)
[Study on chemical composition of ethylacetate fraction from Polygonum amplexicaule var. sinense].
Mei-xian Xiang (2012)
Phytochemical and biological research of Polygoneae medicinal resources 527
10.1142/S0192415X14500396
Blood pressure lowering effect of Korea ginseng derived ginseol K-g1.
Moo-Yong Rhee (2014)
10.1007/s10265-010-0394-6
Evolution and origins of the Mazatec hallucinogenic sage, Salvia divinorum (Lamiaceae): a molecular phylogenetic approach
Aaron A. Jenks (2010)
10.1016/j.ygeno.2011.03.012
De novo transcriptome sequencing in Salvia miltiorrhiza to identify genes involved in the biosynthesis of active ingredients.
Hua Wenping (2011)
10.1159/000363012
Stimulation of Eryptosis by Cryptotanshinone
Rosi Bissinger (2014)
10.1016/j.biocel.2014.03.005
Salvianolic acid B promotes osteogenesis of human mesenchymal stem cells through activating ERK signaling pathway.
Daohua Xu (2014)
10.1007/s10571-014-0085-2
Anti-apoptotic Effect of Taxodione on Serum/Glucose Deprivation-Induced PC12 Cells Death
Negar Shafaei-Bajestani (2014)
10.4268/cjcmm20140918
[Chemical constituents of leaves of Panax japonicus var. major].
Rui He (2014)
10.1016/j.jep.2014.07.010
Tanshinone IIA, a major component of Salvia milthorriza Bunge, inhibits platelet activation via Erk-2 signaling pathway.
Francesco Maione (2014)
10.1021/np1002516
Sesterterpenoids and other constituents of Salvia sahendica.
Firouz Matloubi Moghaddam (2010)
a traditional medicine used in China and Korea, improves 2, 4-dinitrofluorobenzene-induced atopic dermatitis-like lesional skin
P. tinctorium (2014)
10.3390/molecules19021592
Resveratrol-4-O-d-(2'-galloyl)-glucopyranoside Isolated from Polygonum cuspidatum Exhibits Anti-Hepatocellular Carcinoma Viability by Inducing Apoptosis via the JNK and ERK Pathway
Qichao Xie (2014)
10.1371/journal.pone.0102689
Anti-Wrinkle Effect of Magnesium Lithospermate B from Salvia miltiorrhiza BUNGE: Inhibition of MMPs via NF-kB Signaling
Yu Ri Jung (2014)
10.3390/molecules19068189
Standardized Salvia miltiorrhiza Extract Suppresses Hepatic Stellate Cell Activation and Attenuates Steatohepatitis Induced by a Methionine-Choline Deficient Diet in Mice
Hak Sung Lee (2014)
10.1080/14786419.2011.628668
A new highly hydroxylated triterpene from Salvia atropatana Bunge
Zohreh Habibi (2012)
10.1248/CPB.59.1417
Oleanolic triterpene saponins from the roots of Panax bipinnatifidus.
Hữu Tùng Nguyễn (2011)
10.1016/j.tox.2014.04.002
Stereospecific effects of ginsenoside 20-Rg3 inhibits TGF-β1-induced epithelial-mesenchymal transition and suppresses lung cancer migration, invasion and anoikis resistance.
Youngjoo Kim (2014)
10.1007/s12272-014-0425-2
Anti-fibrotic effect of PF2401-SF, a standardized fraction of Salvia miltiorrhiza, in thioacetamide-induced experimental rats liver fibrosis
Daya Ram Parajuli (2015)
10.1002/cbdv.200790011
Guaiane sesquiterpene lactones from Salvia nubicola (Lamiaceae).
Muhammad Shaiq Ali (2007)
10.1016/j.fitote.2014.08.018
Salvianolic acids T and U: a pair of atropisomeric trimeric caffeic acids derivatives from root of Salvia miltiorrhiza.
Wei Li (2014)
10.1055/s-2002-32069
Hepatoprotective effect of majonoside R2, the major saponin from Vietnamese ginseng (Panax vietnamensis).
Quan le Tran (2002)
10.1186/1472-6882-14-183
Bidirectional regulation of angiogenesis and miR-18a expression by PNS in the mouse model of tumor complicated by myocardial ischemia
Qinbo Yang (2014)
10.1016/j.ympev.2014.04.017
Phylogeny and historical biogeography of Isodon (Lamiaceae): rapid radiation in south-west China and Miocene overland dispersal into Africa.
Xiang-Qin Yu (2014)
10.1055/s-2003-41117
Phylogenetic relationship in the genus Panax: inferred from chloroplast trnK gene and nuclear 18S rRNA gene sequences.
Shu Gao Zhu (2003)
10.1016/S0305-1978(99)00117-9
Quercetin 3-O-(6"-galloyl)-beta-D-galactoside from Polygonum viscosum (Polygonaceae).
Datta (2000)
10.1007/s00213-014-3641-z
Behavioural and neurochemical assessment of salvinorin A abuse potential in the rat
Verónica Serra (2014)
10.1111/jphp.12306
Ginsenoside Rh1 induces mouse osteoblast growth and differentiation through the bone morphogenetic protein 2/runt-related gene 2 signalling pathway.
Muhammad Hanif Siddiqi (2014)
10.1186/1471-2164-15-73
Combining metabolomics and transcriptomics to characterize tanshinone biosynthesis in Salvia miltiorrhiza
Wei Gao (2013)
10.1055/s-0029-1185382
Molecular authentication of the traditional medicinal plant Fallopia multiflora.
Chuanjin Zheng (2009)
10.1007/s12272-012-0909-x
Inhibition of DNA topoisomerases I and II of compounds from Reynoutria japonica
Kyoung Hwangbo (2012)
10.4238/2012.October.4.1
Phylogeny and systematics of Indian Polygonum sensu lato in the subfamily Polygonoideae based on ITS sequences of nuclear ribosomal DNA.
Ritesh Kumar Choudhary (2012)
10.1186/1471-2164-12-S5-S5
Analysis of the transcriptome of Panax notoginseng root uncovers putative triterpene saponin-biosynthetic genes and genetic markers
Hongmei Luo (2011)
10.1055/s-2008-1081330
Genetic variation and identification of cultivated Fallopia multiflora and its wild relatives by using chloroplast matK and 18S rRNA gene sequences.
Ping Yan (2008)
10.1016/j.gene.2013.07.009
Potential use of DNA barcoding for the identification of Salvia based on cpDNA and nrDNA sequences.
Meng Wang (2013)
10.1186/1472-6882-13-282
Polygonum cuspidatum inhibits pancreatic lipase activity and adipogenesis via attenuation of lipid accumulation
Young Sook Kim (2013)
10.1080/10286020.2013.769966
A new sesquiterpene lactone from Salvia plebeia
Shu-Yong Cao (2013)
10.3892/ijo.2014.2471
Tanshinone IIA induces cytochrome c-mediated caspase cascade apoptosis in A549 human lung cancer cells via the JNK pathway.
Jian Zhang (2014)
10.1016/S0254-6272(14)60083-2
Effects of radix ginseng on microbial infections: a narrative review.
Hong hua Wu (2014)
Content of resveratrol and glycoside
S. Kurita (2014)
The effect of hydro alcoholic extract of seven plants on cariogenic bacteria--an in vitro evaluation.
Hamid Kermanshah (2014)
10.3390/ijms150711566
Two Diterpenoids and a Cyclopenta[c]pyridine Derivative from Roots of Salvia digitaloids
Shwu-Jen Wu (2014)
10.3732/ajb.1100549
Phylogenetics, biogeography, and staminal evolution in the tribe Mentheae (Lamiaceae).
B. T. Drew (2012)
[Transcriptome characterization for Salvia miltiorrhiza using 454 GS FLX].
Ying Li (2010)
Essential oil composition, antioxidant and antifungal activities of Salvia sclarea L. from Munzur Valley in Tunceli, Turkey.
Ebru Yuce (2014)
10.4103/1008-682X.129129
Panax ginseng induces the expression of CatSper genes and sperm hyperactivation
Eun Hwa Park (2014)
10.1007/s11033-011-0792-4
CAPS markers using mitochondrial consensus primers for molecular identification of Panax species and Korean ginseng cultivars (Panax ginseng C. A. Meyer)
Jei-Wan Lee (2011)
10.1016/j.redox.2013.08.006
Effect of Nrf2 activators on release of glutathione, cysteinylglycine and homocysteine by human U373 astroglial cells☆
Megan L. Steele (2013)
10.1016/j.jgr.2013.11.011
Metabolomic approach for discrimination of processed ginseng genus (Panax ginseng and Panax quinquefolius) using UPLC-QTOF MS
Hee-Won Park (2014)
10.1016/j.lfs.2005.09.008
Psychopharmacology of the hallucinogenic sage Salvia divinorum.
Thomas E. Prisinzano (2005)
10.1111/cns.12270
Systematic review of clinical trials assessing pharmacological properties of Salvia species on memory, cognitive impairment and Alzheimer's disease.
Marco Miroddi (2014)
10.1016/j.jpba.2014.06.031
Adulteration and cultivation region identification of American ginseng using HPLC coupled with multivariate analysis.
Chunhao Yu (2014)
10.1016/j.fsigen.2011.07.013
Botanical DNA evidence in criminal cases: Knotgrass (Polygonum aviculare L.) as a model species.
Wim J. M. Koopman (2012)
10.4103/0973-1296.111288
Sterols isolated from seeds of Panax ginseng and their antiinflammatory activities
Jeong Ah Kim (2013)
[Analysis of head volatile constituents of Polyonum cuspidatum flower by HS-GC/MS].
Yin-shi Sun (2012)
10.1016/j.gene.2009.10.004
One-step identification of conserved miRNAs, their targets, potential transcription factors and effector genes of complete secondary metabolism pathways after 454 pyrosequencing of calyx cDNAs from the Labiate Salvia sclarea L.
Sylvain Legrand (2010)
10.12980/APJTB.4.2014C1270
Salvia fruticosa reduces intrinsic cellular and H2O2-induced DNA oxidation in HEK 293 cells; assessment using flow cytometry.
Saleem Bani Hani (2014)
10.1111/1755-5922.12077
Modulation of endothelial function by Korean red ginseng (Panax ginseng C.A. Meyer) and its components in healthy individuals: a randomized controlled trial.
Elena Jovanovski (2014)
10.1016/j.phytochem.2014.03.009
Triterpenoids from Salvia argentea var. aurasiaca (Pomel) Batt. & Trab. and their chemotaxonomic significance.
Hichem Lakhal (2014)
10.4268/cjcmm20131606
[Study on sequence characterized amplified region (SCAR) markers of Polygonum capitatum].
Tao Zhou (2013)
10.1016/j.bbrc.2014.04.056
Panax red ginseng extract regulates energy expenditures by modulating PKA dependent lipid mobilization in adipose tissue.
Hae-Mi Cho (2014)
10.1186/1471-2164-14-245
Transcriptome analysis reveals ginsenosides biosynthetic genes, microRNAs and simple sequence repeats in Panax ginseng C. A. Meyer
Chunfang Li (2012)
10.4238/2014.JULY.25.19
CYP1A2 polymorphism in Chinese patients with acute liver injury induced by Polygonum multiflorum.
Ma Kf (2014)
10.1002/ptr.4690
Antiproliferative activity of polygonaceae species from the Carpathian Basin against human cancer cell lines.
Ildikó Lajter (2013)
10.4268/cjcmm20140816
[A new chromone glycoside from roots of Polygonum multiflorum].
Hui-nan Zhao (2014)
10.1016/j.phytochem.2013.03.021
Malonyl-ginsenoside content of a cell-suspension culture of Panax japonicus var. repens.
D. V. Kochkin (2013)
Stilbene glucoside inhibits the glucuronidation
J. Ma (2013)
10.1111/j.1745-7254.2008.00868.x
Comparison of the pharmacological effects of Panax ginseng and Panax quinquefolium
Chieh-fu Chen (2008)
10.3109/13880209.2014.898076
Evaluation of the anti-diarrheal activity of Salvia connivens
Salud Pérez Gutiérrez (2014)
Hexane extracts of Polygonum multiflorum
S. V. Lee (2014)
10.1016/j.jgr.2013.11.013
New dammarane-type triterpenoids from the leaves of Panax notoginseng and their protein tyrosine phosphatase 1B inhibitory activity
Dawei Li (2014)
10.1155/2014/539607
Apoptosis Induction by Polygonum minus Is Related to Antioxidant Capacity, Alterations in Expression of Apoptotic-Related Genes, and S-Phase Cell Cycle Arrest in HepG2 Cell Line
Mohd Alfazari Mohd Ghazali (2014)
Aedes albopictus L
S. Matesanz (2014)
10.1021/np200559c
Triterpenoids with rare carbon skeletons from Salvia hydrangea: antiprotozoal activity and absolute configurations.
Mahdi Moridi Farimani (2011)
10.1021/np400337a
Antitrypanosomal triterpenoid with an ε-lactone E-ring from Salvia urmiensis.
Mahdi Moridi Farimani (2013)
10.5142/jgr.2013.37.300
20S-dihydroprotopanaxatriol modulates functional activation of monocytes and macrophages
Mi-Yeon Kim (2013)
10.1248/CPB.60.728
New triterpenoid saponins from fruit specimens of Panax japonicus collected in Toyama prefecture and Hokkaido (2).
Kouichi Yoshizaki (2012)
10.1007/s12272-001-2100-7
A new stilbene glucoside gallate from the roots of Polygonum multiflorum
Hyun Ki Kim (2008)
10.1021/np5002303
Dammarane triterpenes as potential SIRT1 activators from the leaves of Panax ginseng.
Jun-li Yang (2014)
10.1016/j.fct.2014.06.025
Differential effect of manool--a diterpene from Salvia officinalis, on genotoxicity induced by methyl methanesulfonate in V79 and HepG2 cells.
H D Nicolella (2014)
10.1016/j.antiviral.2006.04.014
Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 interaction
Tin-Yun Ho (2007)
10.1002/pca.1076
Flavonoid glucuronides with anti-leukaemic activity from Polygonum amphibium L.
Helena Danuta Smolarz (2008)
10.1111/cas.12359
2-Methoxystypandrone inhibits signal transducer and activator of transcription 3 and nuclear factor-κB signaling by inhibiting Janus kinase 2 and IκB kinase
Shan Kuang (2014)
10.1371/journal.pone.0101291
Ginsenoside Rg1 Prevents Cognitive Impairment and Hippocampus Senescence in a Rat Model of D-Galactose-Induced Aging
Jiahong Zhu (2014)
capitatum has antibacterial activity and can be used in bladder infection
P. Guizhou Miao medicine (2014)
10.1016/j.phymed.2014.05.004
Antioxidative effects of Panax notoginseng saponins in brain cells.
Ningna Zhou (2014)
10.1371/journal.pone.0098232
The Effect of Lithospermic Acid, an Antioxidant, on Development of Diabetic Retinopathy in Spontaneously Obese Diabetic Rats
Cheng Ji Jin (2014)
10.1016/j.bmcl.2014.08.009
20(S)-Ginsenoside Rh2 as aldose reductase inhibitor from Panax ginseng.
Sri Fatmawati (2014)
10.3109/13880209.2014.889720
Salvia miltiorrhiza compounds protect the liver from acute injury by regulation of p38 and NFκB signaling in Kupffer cells
Shu-qiang Yue (2014)
10.1371/journal.pone.0080464
Transcriptome Analysis of Medicinal Plant Salvia miltiorrhiza and Identification of Genes Related to Tanshinone Biosynthesis
Lei Yang (2013)
In vitro and in vivo studies of the inhibitory effects of emodin isolated from Polygonum cuspidatum on Coxsackievirus B₄
Z Liu (2013)
Phytochemical and biological research of Polygoneae medicinal resources 525
[Chemical constituents in herbs of Polygonum jucundum].
Yun Ming Lin (2009)
10.1016/j.taap.2012.07.003
A new herb-drug interaction of Polygonum cuspidatum, a resveratrol-rich nutraceutical, with carbamazepine in rats.
Ying-Chang Chi (2012)
10.1055/S-0032-1315121
Small-molecule STAT3 signaling pathway modulators from Polygonum cuspidatum.
Jiawei Liu (2012)
10.1016/j.jtbi.2010.05.008
A simple method to analyze the similarity of biological sequences based on the fuzzy theory.
Wei Huang (2010)
10.1111/j.1399-3054.2009.01309.x
Transcript profiles of Panax quinquefolius from flower, leaf and root bring new insights into genes related to ginsenosides biosynthesis and transcriptional regulation.
Qiong Wu (2010)
10.1016/j.jgr.2013.12.005
Evidence of genome duplication revealed by sequence analysis of multi-loci expressed sequence tag–simple sequence repeat bands in Panax ginseng Meyer
Nam-Hoon Kim (2014)



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