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Solid Lipid Nanoparticles For Targeting And Delivery Of Drugs And Genes
Rakesh K Tekade, Rahul Maheshwari, M. Tekade, M. Chougule
Published 2017 · Materials Science
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Most of the biologically active compounds are struggle with low solubility and therefore low bioavailability, biological degradation and inadvertent intrinsic side effects. To overcome such difficulties, the emergence of potential and novel drug carrier system is of supreme importance in terms of their efficient applicability through different routes of administration like skin, oral, topical, parenteral and pulmonary. Considering this, Solid lipid nanoparticles have attracted huge attention for the successful delivery of drugs and genes and also employed as an effective strategy for targeting therapeutics. The potential advantages of solid lipid nanoparticles over other nanoparticles are because of their high biocompatibility, higher drug loading capacity and scalability. In this chapter, we summarize the complete understanding about morphology, methodology, characterization, hybridization and biomedical applications of solid lipid nanoparticles.
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