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Supercritical Fluid Technologies: An Innovative Approach For Manipulating The Solid-state Of Pharmaceuticals.

I. Pasquali, R. Bettini, F. Giordano
Published 2008 · Materials Science, Medicine

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Solid-state, crystallographic purity and careful monitoring of the polymorphism of drugs and excipients are currently an integral part of the development of modern drug delivery systems. The reproducible preparation of organic crystals in a specific form and size is a major issue that must be addressed. A recent approach for obtaining pharmaceutical materials in pure physical form is represented by the technologies based on supercritical fluids. The present work aims to provide a critical review of the recent advances in the use of supercritical fluids for the preparation and control of the specific physical form of pharmaceutical substances with particular attention to those fluids used for drug delivery systems. These innovative technologies are highly promising for future application in particle design and engineering.
This paper references
10.1016/S0378-5173(02)00358-7
Solution-mediated phase transformation of anhydrous to dihydrate carbamazepine and the effect of lattice disorder.
D. Murphy (2002)
10.1002/JPS.1137
Polymorph screening: influence of solvents on the rate of solvent-mediated polymorphic transformation.
C. H. Gu (2001)
10.1016/S0731-7085(00)00262-4
Solid-state study of polymorphic drugs: carbamazepine.
C. Rustichelli (2000)
10.1016/B978-044451574-2/50015-8
Chapter 2.2 – Interfacial Phenomena in Countercurrent and Spray Processing Using Supercritical Fluids
R. Eggers (2004)
10.1007/978-3-662-07380-3_2
Properties of Supercritical and Near-Critical Gases and of Mixtures with Sub- and Supercritical Components
G. Brunner (1994)
10.1016/S0008-6215(02)00284-7
Supercritical CO2 fluid extraction of crystal water from trehalose dihydrate. Efficient production of form II (Tα) phase
K. Akao (2002)
10.1016/S0896-8446(02)00248-6
Micronization of Ibuprofen by RESS
Defne Kayrak (2003)
10.1016/0021-9673(94)01213-X
Extraction of pesticides using supercritical trifluoromethane and carbon dioxide
R. Hillmann (1995)
10.1016/S0378-5173(03)00344-2
Supercritical carbon dioxide treatment as a method for polymorph preparation of deoxycholic acid.
Y. Tozuka (2003)
10.1016/S0928-0987(97)00072-9
Relationship between swelling, erosion and drug release in hydrophillic natural gum mini-matrix formulations.
J. Sujja-areevath (1998)
10.1080/713834046
Formation of Aqueous Small Droplet Aerosols Assisted by Supercritical Carbon Dioxide
R. Sievers (1999)
10.1016/S0896-8446(01)00100-0
Analysis of the supersaturation and precipitation process with supercritical CO2
S. Bristow (2001)
10.1016/S0022-0248(98)01022-7
Crystallization process in turbulent supercritical flows
B.Yu Shekunov (1999)
10.1002/JPS.20578
Pharmaceutical co-crystals.
Peddy Vishweshwar (2006)
10.1021/IE000151A
Micronization by Rapid Expansion of Supercritical Solutions to Enhance the Dissolution Rates of Poorly Water-Soluble Pharmaceuticals
M. Charoenchaitrakool (2000)
10.1016/S0939-6411(03)00092-4
Study of the solid state of carbamazepine after processing with gas anti-solvent technique.
M. Moneghini (2003)
10.1016/0378-5173(94)00132-4
Increased metastable solubility of milled griseofulvin, depending on the formation of a disordered surface structure
A. A. Elamin (1994)
10.1021/JA02086A003
The rate of solution of solid substances in their own solutions
A. A. Noyes (1897)
10.1016/J.ADDR.2003.10.009
Phase transformation considerations during process development and manufacture of solid oral dosage forms.
G. Zhang (2004)
10.1023/A:1011000915769
Characterization of Two Polymorphs of Salmeterol Xinafoate Crystallized From Supercritical Fluids
H. Tong (2004)
10.1016/J.SUPFLU.2004.10.005
Nanoparticle formation in rapid expansion of water-in-supercritical carbon dioxide microemulsion into liquid solution
M. J. Meziani (2005)
10.1016/S0928-0987(00)00108-1
Supercritical fluid processing of proteins. I: lysozyme precipitation from organic solution.
S. Moshashaée (2000)
10.1039/A706669D
Crystal chemistry and solvent effects in polymorphic systems Sulfathiazole
N. Blagden (1998)
10.1211/0022357022656
Open questions on bioequivalence: the case of multiple peak phenomenon
A. Marzo (2004)
10.1021/CM00044A013
Solid-state pharmaceutical chemistry
S. Byrn (1994)
10.1016/S1461-5347(99)00209-6
Strategies for particle design using supercritical fluid technologies.
York (1999)
10.1016/0896-8446(89)90003-X
Solubilities of indole, skatole, and 5-Methoxyindole in supercritical fluids
S. Sako (1989)
10.1615/CRITREVTHERDRUGCARRIERSYST.V18.I2.20
Preparation of drug delivery systems using supercritical fluid technology.
U. Kompella (2001)
10.1016/S0896-8446(99)00027-3
Numerical Modeling of Mass Transfer in the Supercritical Antisolvent Process
Jane O. Werling (1999)
10.1016/0896-8446(89)90004-1
Solubilities of Indole Derivatives in Supercritical fluids
T. Nakatani (1989)
10.1016/J.SUPFLU.2005.11.016
Effect of high-pressure gases on phase behaviour of solid lipids
S. Spilimbergo (2006)
10.1201/9780203021378
Supercritical fluid technology for drug product development
P. York (2004)
10.1023/A:1020477204512
Supercritical Fluids Crystallization of Budesonide and Flunisolide
S. Velaga (2004)
10.1201/9780203908280
Crystallization Technology Handbook
A. Mersmann (2001)
10.1073/pnas.0437744100
Elucidation of crystal form diversity of the HIV protease inhibitor ritonavir by high-throughput crystallization
S. Morissette (2003)
10.1002/JPS.1065
Crystallization of pure anhydrous polymorphs of carbamazepine by solution enhanced dispersion with supercritical fluids (SEDS).
A. D. Edwards (2001)
10.1208/pt030429
Crystal doping aided by rapid expansion of supercritical solutions
Chandra Vemavarapu (2008)
10.1098/rspl.1879.0054
VI. On the solubility of solids in gases
J. Hannay (1879)
10.1016/S0731-7085(00)00390-3
Solid-state studies on the hemihydrate and the anhydrous forms of flunisolide.
M. Bartolomei (2000)
Crystal chemistry and solvent effects in polymorphic systems sulfathiazole (vol 94, pg 1035, 1998)
N. Blagden (1998)
10.1201/9780203908280-12
‘‘Tailor-Made Additives’’ and Impurities
I. Weissbuch (2001)
10.1016/J.SUPFLU.2005.09.005
Formation and stabilization of ibuprofen nanoparticles in supercritical fluid processing
P. Pathak (2006)
10.1021/JS9601896
Characteristics and significance of the amorphous state in pharmaceutical systems.
Bruno C. Hancock (1997)
10.1023/A:1010194020563
Thermal Analysis, Microcalorimetry and Combined Techniques for the Study of Pharmaceuticals
D. Giron (1999)
10.1002/JPS.10186
Physicochemical characterization of solid dispersions of carbamazepine formulated by supercritical carbon dioxide and conventional solvent evaporation method.
S. Sethia (2002)
10.1021/CG034026O
Formation of composite crystals by precipitation in supercritical CO2
B. Shekunov (2003)
10.1016/b978-0-444-51574-2.x5000-7
Supercritical Fluids as Solvents and Reaction Media
G. Brunner (2004)
10.1023/A:1011045729706
Polymorph Control of Sulfathiazole in Supercritical CO2
A. Kordikowski (2004)
10.1023/B:JTAN.0000038999.29199.04
Interaction of pharmaceutical hydrates with supercritical CO2
R. Bettini (2004)
10.1016/0168-3659(91)90046-G
Probing the mechanisms of drug release from hydrogels
P. Lee (1991)
10.1023/A:1015358129817
Influence of Polymorphism on the Surface Energetics of Salmeterol Xinafoate Crystallized from Supercritical Fluids
H. Tong (2004)
10.1002/JPS.3030490417
Some pharmaceutical properties of novobiocin.
J. Mullins (1960)
10.1016/S0378-5173(02)00649-X
Polymorphic properties of micronized carbamazepine produced by RESS.
P. Gosselin (2003)
10.1201/9780203021378-11
Methods of Particle Production
G. Charbit (2004)
10.1016/J.IJPHARM.2003.11.025
Solid dispersion of carbamazepine in PVP K30 by conventional solvent evaporation and supercritical methods.
S. Sethia (2004)
10.1016/J.EJPS.2005.11.007
Solid-state chemistry and particle engineering with supercritical fluids in pharmaceutics.
I. Pasquali (2006)
10.1021/BK-1989-0406.CH022
Gas Antisolvent Recrystallization: New Process To Recrystallize Compounds Insoluble in Supercritical Fluids
P. Gallagher (1989)
10.1023/A:1011957512347
Phase Behavioral Effects on Particle Formation Processes Using Supercritical Fluids
S. Palakodaty (2004)
10.1201/b16941
Advanced Pharmaceutical Solids
J. T. Carstensen (2000)
10.1016/S0928-0987(01)00115-4
Solubility and conversion of carbamazepine polymorphs in supercritical carbon dioxide.
R. Bettini (2001)
10.1016/0378-5173(93)90002-W
Rapid expansion from supercritical solutions: application to pharmaceutical processes
E. Phillips (1993)
10.1201/9780203021378.ch7
Control of physical forms of pharmaceutical substances
A. Chow (2004)
10.1023/A:1025758127358
Thermal Analysis of Trace Levels of Polymorphic Impurity in Salmeterol Xinafoate Samples
H. Tong (2004)
Polymorphism in Pharmaceutical Solids
H. Brittain (1999)
THEORY AND ORIGIN OF POLYMORPHISM
D. J. Grant (1999)
10.1016/J.EJPS.2004.02.001
Optimisation of powders for pulmonary delivery using supercritical fluid technology.
Mahboob Rehman (2004)
10.1021/IE010943K
Supercritical-assisted atomization to produce micro- and/or nanoparticles of controlled size and distribution
E. Reverchon (2002)



This paper is referenced by
Development of supercritical fluid extraction for the recovery of betacyanins from red pitaya fruit (Hylocereus polyrhizus) peel: a source of natural red pigment with potential antioxidant properties
Farahnaz Fathordoobady (2019)
10.1201/B11035-8
Synthesis of Nanocomposite Particles Using Supercritical Fluids: A Bridge with Bio-applications
C. Aymonier (2011)
10.2174/13816128113199990396
Delivery of poorly soluble compounds by amorphous solid dispersions.
T. W. Lee (2014)
10.1016/J.SUPFLU.2013.07.015
Manipulating the size, the morphology and the polymorphism of acetaminophen using supercritical antisolvent (SAS) precipitation
M. Rossmann (2013)
10.1208/s12249-008-9152-7
Formation of Inhalable Rifampicin–Poly(l-lactide) Microparticles by Supercritical Anti-solvent Process
V. Patomchaiviwat (2008)
10.1016/j.addr.2016.01.012
Amorphous solid dispersions: Rational selection of a manufacturing process.
Teófilo Vasconcelos (2016)
10.1016/J.CHERD.2012.05.001
Antisolvent crystallization of carbamazepine from organic solutions
M. Park (2012)
10.1134/S1990793117070028
Fabrication of the Components for a Sustained-Release Injectable Dosage Form of Acetylsalicylic Acid Using Supercritical Carbon Dioxide
E. N. Antonov (2017)
10.1016/j.apt.2020.06.008
Development and validation of a two-dimensional population balance model for a supercritical CO2 antisolvent batch crystallization process
Indu Muthancheri (2020)
10.1016/J.SUPFLU.2015.06.005
Preparation and characterization of baicalein powder micronized by the SEDS process
Yan Tingxuan (2015)
10.4236/JBISE.2011.412091
Polymer-based nanoparticulate solid dispersions prepared by a modified electrospraying process
Deng-Guang Yu (2011)
Insights into particle formation and analysis
Jenni Pessi (2017)
Dissolution enhancement of glibenclamide by solid dispersion: solvent evaporation versus a supercritical fluid-based solvent -antisolvent technique
M. Tabbakhian (2014)
Improved dissolution behavior of lipophilic drugs by solid dispersions: a matter of composition
Parinda Srinarong (2011)
10.2147/IJN.S70340
Preparation and evaluation of cyclosporin A-containing proliposomes: a comparison of the supercritical antisolvent process with the conventional film method
P. R. Karn (2014)
10.1208/s12249-016-0492-4
Using Supercritical Fluid Technology (SFT) in Preparation of Tacrolimus Solid Dispersions
R. Obaidat (2016)
10.1016/j.foodchem.2016.01.121
Effect of solvent type and ratio on betacyanins and antioxidant activity of extracts from Hylocereus polyrhizus flesh and peel by supercritical fluid extraction and solvent extraction.
Farahnaz Fathordoobady (2016)
10.1016/J.JCRYSGRO.2011.11.046
Recrystallization of puerarin using the supercritical fluid antisolvent process
Ying Li (2012)
10.1016/B978-0-12-409547-2.12605-8
Polymorphs of Molecular Crystals
M. Caira (2017)
Title Diffusion coefficients of phenylbutazone in supercritical CO2 and in ethanol
C. Yi (2015)
10.1517/17425247.2011.598147
Improved dissolution behavior of lipophilic drugs by solid dispersions: the production process as starting point for formulation considerations
P. Srinarong (2011)
10.1016/J.SUPFLU.2008.12.005
Compressed CO2 antisolvent precipitation of lysozyme
Francesco Fusaro (2009)
10.1016/J.SUPFLU.2018.07.027
Preparation of 5-fluorouracil microparticles and 5-fluorouracil/poly(l-lactide) composites by a supercritical CO2 antisolvent process
Isaac A. Cuadra (2019)
10.1016/J.AJPS.2014.05.002
A practical guide to pharmaceutical polymorph screening & selection
E. Lee (2014)
10.1002/CEAT.201000462
Micronization of Fluticasone Propionate using Supercritical Antisolvent (SAS) Process
C.-S. Su (2011)
10.1016/j.addr.2011.10.009
Modification of physicochemical characteristics of active pharmaceutical ingredients and application of supersaturatable dosage forms for improving bioavailability of poorly absorbed drugs.
K. Kawakami (2012)
10.3390/CRYST8070298
Cryochemically Obtained Nanoforms of Antimicrobial Drug Substance Dioxidine and Their Physico-chemical and Structural Properties
T. I. Shabatina (2018)
10.14302/ISSN.2328-0182.JAPST-12-145
Supercritical Fluid Technology: A Review
R. Parhi (2013)
10.2147/IJN.S59516
Electrosprayed core–shell solid dispersions of acyclovir fabricated using an epoxy-coated concentric spray head
Zhe-peng Liu (2014)
10.1016/j.powtec.2019.08.090
Optimization of supercritical CO2-assisted spray drying technology for the production of inhalable composite particles using quality-by-design principles
Cláudia Moura (2019)
10.1021/ACS.OPRD.5B00279
Recrystallizing Primidone through Supercritical Antisolvent Precipitation
Hung-Hsin Chen (2016)
10.1016/j.aca.2012.07.010
An overview of the analytical characterization of nanostructured drug delivery systems: towards green and sustainable pharmaceuticals: a review.
C. Domingo (2012)
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