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Acetylcholinesterase And Butyrylcholinesterase Inhibitory Activity Of Some Turkish Medicinal Plants.

I. Orhan, B. Şener, M. I. Choudhary, A. Khalid
Published 2004 · Medicine, Biology

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The chloroform:medianol (1:1) extracts of a number of the plant species belonging to eight families, namely Corydalis solida (L.) Swartz subsp. solida and Glaucium corniculatum (L.) J. H. Rudolph (Papaveraceae), Rhododendron ponticum L. subsp. ponticum and Rhododendron luteum Sweet. (Ericaceae), Buxus sempervirens L. (Buxaceae), Vicia faba L. (Fabaceae), Robinia pseudoacacia L. (Caeselpiniaceae), Tribulus terrestris L. and Zygophyllum fabago L. (Zygophyllaceae), Lycopodium clavatum L. (Lycopodiaceae), Fumaria vaillantii Lois., Fumaria capreolata L., Fumaria kralikii Jordan, Fumaria asepala Boiss., Fumaria densiflora DC., Fumaria flabellata L., Fumaria petteri Reichb. subsp. thuretii (Boiss.) Pugsley, Fumaria macrocarpa Boiss. ex Hausskn., Fumaria cilicica Hauskkn., Fumaria parviflora Lam. and Fumaria judaica Boiss. (Fumariaceae) were screened for their anticholinesterase activity on acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes by in vitro Ellman method at 10 microg/ml and 1 mg/ml concentrations. The extracts did not show any noticeable inhibitory activity against both of the enzymes at 10 microg/ml. The extracts of Rhododendron ponticum subsp. ponticum, Rhododendron luteum, Corydalis solida subsp. solida, Glaucium corniculatum, and Buxus sempervirens showed remarkable inhibitory activity above 50% inhibition rate on AChE at 1 mg/ml. Among them, Rhododendron ponticum subsp. ponticum, Corydalis solida subsp. solida and Buxus sempervirens were the most active extracts against BChE having 95.46 +/- 1.03%, 93.08 +/- 0.97%, and 93.45 +/- 0.88% inhibition rates, respectively. Among the extracts screened, all of the Fumaria extracts displayed highly potent inhibition against both of the enzymes at 1 mg/ml concentration compared to the standard.
This paper references



This paper is referenced by
10.1016/j.fitote.2013.06.010
Isolation, characterization and acetylcholinesterase inhibitory activity of alkaloids from roots of Stemona sessilifolia.
Dong-Hai Lai (2013)
Screening for cholinesterase inhibitors in selected fruits and vegetables
D. Szwajgier (2012)
10.1016/J.JEP.2007.05.006
Acetylcholinesterase and butyrylcholinesterase inhibitory compounds from Corydalis cava Schweigg. & Kort.
A. Adsersen (2007)
10.22037/IJPR.2011.931
Chemical Compositionand Anti-acetyl cholinesterase Activity of Flower Essential Oils of Artemisiaannuaat Different Flowering Stage
Z. Yu (2011)
10.9734/BJPR/2013/4833
Anticholinesterase, Antioxidant and Nitric Oxide Scavenging A ctivity of the Aqueous Extract ofSome Medicinal Plants
R. Agarwal (2013)
10.3390/molecules19079999
Lycodine-Type Alkaloids from Lycopodiastrum casuarinoides and Their Acetylcholinesterase Inhibitory Activity
D. Zhang (2014)
10.1007/s13596-019-00408-7
Phenolic profiling and anti-Alzheimer’s evaluation of Eremobium aegyptiacum
M. Marzouk (2020)
10.15835/NBHA44110259
Total Phenolics, Flavonoids, Condensed Tannins Content of Eight Centaurea Species and Their Broad Inhibitory Activities against Cholinesterase, Tyrosinase, α-Amylase and α-Glucosidase
G. Zengin (2016)
10.1186/s13020-020-00321-1
Niosomes of active Fumaria officinalis phytochemicals: antidiabetic, antineuropathic, anti-inflammatory, and possible mechanisms of action
K. Raafat (2020)
10.1002/JIB.5
Phenolic acids from malt are efficient acetylcholinesterase and butyrylcholinesterase inhibitors
D. Szwajgier (2012)
Anti-acetylcholinesterase activities of leaf extracts of carphalea glaucescens and gnidia glauca from Mbeere North Subcounty, Kenya on chilo partellus larvae
A. W. Njoroge (2016)
10.1021/acs.jafc.5b04168
Dihydroagarofuranoid Sesquiterpenes as Acetylcholinesterase Inhibitors from Celastraceae Plants: Maytenus disticha and Euonymus japonicus.
J. Alarcón (2015)
10.1007/s13197-011-0572-0
Inhibitory effect of some tropical green leafy vegetables on key enzymes linked to Alzheimer’s disease and some pro-oxidant induced lipid peroxidation in rats’ brain
G. Oboh (2011)
10.1016/J.JEP.2005.09.032
Screening of plants used in Danish folk medicine to treat memory dysfunction for acetylcholinesterase inhibitory activity.
A. Adsersen (2006)
10.1016/j.jep.2013.02.022
The genus Rhododendron: an ethnopharmacological and toxicological review.
R. Popescu (2013)
10.1016/J.FOODCHEM.2007.12.070
Antioxidant and antiacetylcholinesterase activities of essential oils from Cymbopogon schoenanthus L. Spreng. Determination of chemical composition by GC–mass spectrometry and 13C NMR
Ayda Khadri (2008)
10.1515/znc-2008-7-813
Activity of Essential Oils and Individual Components against Acetyland Butyrylcholinesterase
I. Orhan (2008)
Anti-amnesic effect of aqueous extract of Crataeva nurvala stem bark in scopolamine induced amnesia -
Anshul Tanwar (2014)
10.1007/s12272-014-0515-1
Acetyl- and butyryl-cholinesterase inhibitory activities of the edible brown alga Eisenia bicyclis
J. Choi (2015)
10.1016/j.micpath.2016.03.003
Chemical composition and in vitro evaluation of antioxidant, antimicrobial, cytotoxicity and anti-acetylcholinesterase properties of Tunisian Origanum majorana L. essential oil.
Hafedh Hajlaoui (2016)
10.1155/2014/498629
Anticholinesterase and Antioxidative Properties of Aqueous Extract of Cola acuminata Seed In Vitro
G. Oboh (2014)
10.5219/866
Inhibitory effect of aqueous extracts of raw and roasted Sesamum indicum L. seeds on key enzymes linked to type-2 diabetes (α-amylase and α-glucosidase) and Alzheimer’s disease (acetylcholinesterase and butyrylcholinesterase)
J. Talabi (2018)
Evaluation of selected Libyan medicinal plant extracts for their antioxidant and anticholinesterase activities
F. M. Elmestiri (2007)
10.1515/znc-2007-11-1210
Screening of Various Phenolic Acids and Flavonoid Derivatives for their Anticholinesterase Potential
I. Orhan (2007)
10.3390/molecules21050639
In Vitro Antioxidant, Anti-Diabetes, Anti-Dementia, and Inflammation Inhibitory Effect of Trametes pubescens Fruiting Body Extracts
Kyung Hoan Im (2016)
10.1080/14786419.2010.487188
An aporphine alkaloid from Nelumbo nucifera as an acetylcholinesterase inhibitor and the primary investigation for structure–activity correlations
Z. Yang (2012)
Acetylcholinesterase Inhibitory Effect of Pseuderanthemum palatiferum in Albino Rats
Wararut Buncharoen (2010)
10.1016/j.jep.2016.06.037
Inhibitory activities of major anthraquinones and other constituents from Cassia obtusifolia against β-secretase and cholinesterases.
Hyun Ah Jung (2016)
10.4197/SCI.20-1.13
The Genetic Effect of the Combined Action of Vincristine and Fennel Plant Extract on the Germ Cells of Drosophilla melanogaster
N. H. Al-Twany (2008)
10.1088/1742-6596/1341/2/022003
Utilization of Nypa fruit in Alzheimer’s Disease: An In Silico Approach
Sulfahri (2019)
10.1016/B978-0-444-64183-0.00008-7
Alkaloids as Potential Multi-Target Drugs to Treat Alzheimer's Disease
J. A. Lima (2019)
10.1211/jpp/61.01.0014
Triclisia sacleuxii (Pierre) Diels (Menispermaceae), a potential source of acetylcholinesterase inhibitors.
S. Murebwayire (2009)
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