Online citations, reference lists, and bibliographies.
Please confirm you are human
(Sign Up for free to never see this)
← Back to Search

Improvement Of The Inverse-gated-decoupling Sequence For A Faster Quantitative Analysis Of Various Samples By 13C NMR Spectroscopy.

P. Giraudeau, E. Baguet
Published 2006 · Chemistry, Medicine

Save to my Library
Download PDF
Analyze on Scholarcy
Share
The inverse-gated-decoupling sequence enables quantitative (1)H decoupled (13)C spectra to be obtained. We modified this sequence so as to obtain the same result in less time for molecules containing carbons with various relaxation properties. For that, we determined the optimal (13)C longitudinal-magnetization initial value for a faster relaxation while (1)H decoupler is stopped. This value can be calculated precisely via the nuclear Overhauser effects, the longitudinal relaxation times, together with the determination of the relaxation rate constants of carbons while (1)H are out of equilibrium. A supplementary delay of (1)H decoupling and/or a series of selective pulses applied at the beginning of the recovery delay allow an acceleration of (13)C longitudinal relaxation. We applied this method to the molecule of vanillin. The simultaneous quantification of all carbons was carried out with a recovery delay divided by two compared to the usual sequence.
This paper references
10.1016/0022-2364(72)90194-1
Proton-decoupled NMR. Spectra of carbon-13 With the nuclear overhauser effect suppressed
R. Freeman (1972)
10.1016/0079-6565(77)80003-4
Some quantitative applications of 13C NMR spectroscopy
J. N. Shoolery (1977)
10.1016/0022-2364(76)90122-0
Choice of pulse spacings for accurate T1 and NOE measurements in NMR spectroscopy
R. Harris (1976)
10.1021/AC0496998
NMR approach to the quantification of nonstatistical 13C distribution in natural products: vanillin.
E. Tenailleau (2004)
10.1081/AL-120016544
IMPROVEMENT IN QUANTITATIVE ACCURACY OF 13C DEPT INTEGRALS BY PARAMETER-OPTIMIZATION
N. Karabulut (2002)
10.1051/ANALUSIS:1999157
Simultaneous quantification of free and esterified cholesterol extracted from plasma by 13C NMR spectroscopy
E. Baguet (1999)
10.1103/PHYSREV.99.559
Relaxation Processes in a System of Two Spins
I. Solomon (1955)
10.1016/0022-2364(82)90286-4
Distortionless enhancement of NMR signals by polarization transfer
D. Doddrell (1982)
10.1016/0022-2364(76)90220-1
Systematic errors due to improper waiting times in heteronuclear overhauser effect measurements by the gated decoupling technique
D. Canet (1976)
10.1016/J.CRCI.2005.06.030
Improvement of the inverse-gated-decoupling sequence for a faster quantitative analysis by 13C NMR
P. Giraudeau (2006)
10.1002/(SICI)1097-458X(199712)35:133.0.CO;2-E
13C NMR analysis of the triacylglycerol composition of Greek virgin olive oils
T. Mavromoustakos (1997)
10.1016/0305-0491(95)00070-4
Quantitative high-resolution 13C nuclear magnetic resonance of anserine and lactate in white muscle of Atlantic salmon (Salmo salar)
M. Aursand (1995)
10.1063/1.432503
Dynamics of nuclear Overhauser enhancement in proton decoupled carbon‐13 nuclear magnetic resonance
S. Opella (1976)



This paper is referenced by
10.1016/j.phytochem.2015.08.018
A study on the biosynthesis of hygrophorone B(12) in the mushroom Hygrophorus abieticola reveals an unexpected labelling pattern in the cyclopentenone moiety.
Alexander Otto (2015)
Compréhension moléculaire et prédiction des propriétés physicochimiques dans les produits pétroliers
Jean-Jérôme da Costa Soares (2017)
10.1016/j.jmr.2008.11.016
Sensitive, quantitative carbon-13 NMR spectra by mechanical sample translation.
K. Donovan (2009)
10.1039/C6RA27042E
Design, synthesis, structure, toxicology and in vitro testing of three novel agents for Alzheimer’s disease
J. D. Figueroa-Villar (2017)
10.1002/9783527655861.CH9
NMR‐Based Metabolomics Analysis
Andrea Lubbe (2013)
Ornamental bulb crops as sources of medicinal and industrial natural products
Andrea Lubbe (2013)
10.1016/j.aca.2012.12.003
Quality assessment and authentication of virgin olive oil by NMR spectroscopy: a critical review.
P. Dais (2013)
10.1016/j.pnmrs.2016.01.005
Applications of NMR spectroscopy to systems biochemistry.
T. W. Fan (2016)
10.1021/MA501196H
PEG-Based Hyperbranched Polymer Theranostics: Optimizing Chemistries for Improved Bioconjugation
A. Ardana (2014)
10.1002/9781119286325.CH6
NMR Spectroscopy in Bitumen Characterization
Catarina Varanda (2017)
10.1016/j.talanta.2013.02.024
Green coffee oil analysis by high-resolution nuclear magnetic resonance spectroscopy.
N. D’Amelio (2013)
10.1016/j.carres.2020.108067
Substituent distribution of propyl cellulose studied by nuclear magnetic resonance.
H. Kono (2020)
10.3390/ijms21165832
Controlled Drug Release and Cytotoxicity Studies of Beta-Lapachone and Doxorubicin Loaded into Cyclodextrins Attached to a Polyethyleneimine Matrix
A. Kowalczyk (2020)
10.1039/c4cc04695a
Hemicarceplex formation allows ready identification of the isomers of the metallofullerene Sc3N@C80 using (1)H and (13)C NMR spectroscopy.
M. Ku (2014)
10.1016/J.PNMRS.2008.02.001
NMR for microbiology: In vivo and in situ applications
J. Grivet (2009)
10.1016/B978-0-12-397922-3.00003-4
Fast and Ultrafast Quantitative 2D NMR
P. Giraudeau (2013)
10.1016/J.PNMRS.2007.03.002
Structure-based profiling of metabolites and isotopomers by NMR
T. Fan (2008)
10.1016/B978-0-12-397922-3.00003-4
Chapter Three – Fast and Ultrafast Quantitative 2D NMR: Vital Tools for Efficient Metabolomic Approaches
P. Giraudeau (2013)
10.1016/S0066-4103(08)00401-8
Chapter 1 Quantitative 2D NMR Studies
H. Koskela (2009)
10.1016/j.jaap.2020.104837
In-depth structural characterization of the lignin fraction of a pine-derived pyrolysis oil
M. Figueiredo (2020)
Semantic Scholar Logo Some data provided by SemanticScholar