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Protein-mimetic Peptide Nanofibers: Motif Design, Self-assembly Synthesis, And Sequence-specific Biomedical Applications
Wensi Zhang, X. Yu, Y. Li, Zhiqiang Su, K. Jandt, G. Wei
Published 2017 · Chemistry
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Abstract The design and fabrication of self-assembled peptide nanostructures offer an amazing platform for creating functional nanomaterials for various biomedical applications. Utilizing the mechanical and biological advantages of the protein-mimetic peptide (PMP) system, and combining self-assembled PMP nanofibers with other nanomaterials like nanoparticles, the fabricated PMP-based hybrid fibrous nanostructures can serve as promising candidates for advanced technological applications. In this review, we present the design, synthesis, modification, and fabrication of PMP nanofibers by mimicking the properties and functions of several types of proteins, including extracellular matrix proteins, silk proteins, amyloid proteins, and heparin. The sequence and motif design of PMPs, and the relationships between the design of PMP monomers and the fabrication of functional fibrous biomaterials are introduced and discussed. Furthermore, we summarize a basic classification of various peptide motifs, and provide some instructions for the function-based design of peptide nanostructures, in which some issues on the motif design and function tailoring are discussed. Finally, the recent advances in the PMP nanofiber-based functional nanomaterials in biomineralization, cell culture, tissue regeneration, drug delivery, hemostasis, bioimaging, and biosensors are presented in detail. We believe that this review will be very helpful for researchers to understand the property-specific molecular design, controllable supramolecular self-assembly, and motif-specific applications of both peptides and proteins.
This paper references
Alternate layer-by-layer assembly of graphene oxide nanosheets and fibrinogen nanofibers on a silicon substrate for a biomimetic three-dimensional hydroxyapatite scaffold.
J. Wang (2014)
Energetics of β-turn formation in a mutant peptide YPGDV from influenza hemagglutinin: an MD simulation study.
Rashmi Tambe Shukla (2013)
Advances in nanofibrous scaffolds for biomedical applications: From electrospinning to self-assembly
R. Wade (2014)
The extracellular matrix: at the center of it all.
S. Bowers (2010)
Self-assembly of collagen-mimetic peptide amphiphiles into biofunctional nanofiber.
Jingnan Luo (2011)
Enzyme‐Mediated Degradation of Peptide‐Amphiphile Nanofiber Networks
Ho-Wook Jun (2005)
Hierarchical structure and nanomechanics of collagen microfibrils from the atomistic scale up.
A. Gautieri (2011)
Natural Silk as a Photonics Component: a Study on Its Light Guiding and Nonlinear Optical Properties
S. Kujala (2016)
Sequence Programmable Peptoid Polymers for Diverse Materials Applications.
Abigail S Knight (2015)
Generation of Synthetic Elastin-Mimetic Small Diameter Fibers and Fiber Networks
L. Huang (2000)
Multi-hierarchical self-assembly of a collagen mimetic peptide from triple helix to nanofibre and hydrogel.
Lesley E. R. O'Leary (2011)
Review self‐assembly of amphipathic β‐sheet peptides: Insights and applications
Charles J. Bowerman (2012)
Ca2+-induced self-assembly of Bombyx mori silk sericin into a nanofibrous network-like protein matrix for directing controlled nucleation of hydroxylapatite nano-needles.
Mingying Yang (2015)
Enhanced integrin mediated signaling and cell cycle progression on fibronectin mimetic peptide amphiphile monolayers.
K. Shroff (2012)
Controlled release of doxorubicin and Smac-derived pro-apoptotic peptide from self-assembled KLD-based peptide hydrogels
Eliya Yishay-Safranchik (2014)
Synthetic cationic amphiphilic α-helical peptides as antimicrobial agents.
N. Wiradharma (2011)
Self-assembling polymer systems for advanced treatment of cancer and inflammation
R. Palao-Suay (2016)
Self-Assembled Peptide Nanofibers Encapsulated with Superfine Silver Nanoparticles via Ag⁺ Coordination.
Y. Hu (2015)
Two-Step Self-Assembly of Liposome-Multidomain Peptide Nanofiber Hydrogel for Time-Controlled Release
N. Wickremasinghe (2014)
Metal-directed, chemically-tunable assembly of one-, two- and three-dimensional crystalline protein arrays
Jeffrey D. Brodin (2012)
Protein recognition using synthetic small-molecular binders toward optical protein sensing in vitro and in live cells.
Ryou Kubota (2015)
Promotion of peptide antimicrobial activity by fatty acid conjugation.
A. Chu-Kung (2004)
Self-assembly of Surfactant-like Peptides with Variable Glycine Tails to Form Nanotubes and Nanovesicles
Steve Santoso (2002)
Synergism between platelet collagen receptors defined using receptor-specific collagen-mimetic peptide substrata in flowing blood.
N. Pugh (2010)
Mapping structural landmarks, ligand binding sites, and missense mutations to the collagen IV heterotrimers predicts major functional domains, novel interactions, and variation in phenotypes in inherited diseases affecting basement membranes
J. Parkin (2011)
Enzyme-Instructed Self-Assembly of Small d-Peptides as a Multiple-Step Process for Selectively Killing Cancer Cells
J. Zhou (2016)
Real-time Detection of Breast Cancer Cells Using Peptide-functionalized Microcantilever Arrays
H. Etayash (2015)
When biomolecules meet graphene: from molecular level interactions to material design and applications.
D. Li (2016)
Serial silver clusters biomineralized by one peptide.
Yanyan Cui (2011)
The effect of a recombinant elastin-mimetic coating of an ePTFE prosthesis on acute thrombogenicity in a baboon arteriovenous shunt.
S. Jordan (2007)
Regenerative effects of peptide nanofibers in an experimental model of Parkinson's disease.
Melike Sever (2016)
A Nanostructured Synthetic Collagen Mimic for Hemostasis
V. Kumar (2014)
Surface immobilization of a protease through an inhibitor-derived affinity ligand: a bioactive surface with defensive properties against an inhibitor.
Zengchao Tang (2015)
The physical properties of supramolecular peptide assemblies: from building block association to technological applications.
Lihi Adler-Abramovich (2014)
In situ-forming injectable hydrogels for regenerative medicine
J. Yang (2014)
Formation of Functionalized Nanowires by Control of Self‐Assembly Using Multiple Modified Amyloid Peptides
Hiroki Sakai (2013)
Cooperative effect of heparan sulfate and laminin mimetic peptide nanofibers on the promotion of neurite outgrowth.
B. Mammadov (2012)
Green electrospun pantothenic acid/silk fibroin composite nanofibers: fabrication, characterization and biological activity.
Linpeng Fan (2014)
Tat peptide-mediated intracellular delivery of pharmaceutical nanocarriers.
V. Torchilin (2008)
Molecular Mechanisms of RADA16-1 Peptide on Fast Stop Bleeding in Rat Models
T. Wang (2012)
Amphiphilic peptides and their cross-disciplinary role as building blocks for nanoscience.
S. Cavalli (2010)
Effect of linker and spacer on the design of a fibronectin-mimetic peptide evaluated via cell studies and AFM adhesion forces.
Jennifer A. Craig (2008)
Inhibition of cancer cell proliferation by designed peptide amphiphiles.
L. Aulisa (2009)
Self‐assembled peptide nanofiber templated ALD growth of TiO2 and ZnO semiconductor nanonetworks
Ruslan Garifullin (2016)
Controlled peptide coated nanostructures via the self-assembly of functional peptide building blocks
Xiao-Ding Xu (2012)
Molecular structure of RADA16-I designer self-assembling peptide nanofibers.
Ashley R Cormier (2013)
Controlled self-assembly and templated metallization of fibrinogen nanofibrils.
Gang Wei (2008)
Tuning Cellular Uptake of Molecular Probes by Rational Design of Their Assembly into Supramolecular Nanoprobes.
Lye Lin Lock (2016)
Nogo-66 receptor antagonist peptide promotes axonal regeneration
T. Grandpre (2002)
Biomimetic growth of hydroxyapatite on super water-soluble carbon nanotube-protein hybrid nanofibers
Gang Wei (2011)
Nanomechanics of functional and pathological amyloid materials.
T. Knowles (2011)
Mechanical properties of amyloid-like fibrils defined by secondary structures.
Christian Bortolini (2015)
Silk Nanofiber-Networked Bio-Triboelectric Generator: Silk Bio-TEG
Hyunjun Kim (2016)
Nucleation and Growth of Ordered Arrays of Silver Nanoparticles on Peptide Nanofibers: Hybrid Nanostructures with Antimicrobial Properties
Elena Pazos (2016)
Intrafibrillar collagen mineralization produced by biomimetic hierarchical nanoapatite assembly.
Y. Liu (2011)
Glycosaminoglycan mimetic peptide nanofibers promote mineralization by osteogenic cells.
Samet Kocabey (2013)
A short water-soluble self-assembling peptide forms amyloid-like fibrils.
S. Ray (2006)
Mimicking the extracellular matrix with functionalized, metal-assembled collagen peptide scaffolds.
Victor Hernandez-Gordillo (2014)
Dissecting the structural determinants for the difference in mechanical stability of silk and amyloid beta-sheet stacks.
Senbo Xiao (2013)
A laminin mimetic peptide SIKVAV-conjugated chitosan hydrogel promoting wound healing by enhancing angiogenesis, re-epithelialization and collagen deposition.
Shixuan Chen (2015)
RGD and BMP-2 mimetic peptide crosstalk enhances osteogenic commitment of human bone marrow stem cells.
I. Bilem (2016)
Surface modification and endothelialization of biomaterials as potential scaffolds for vascular tissue engineering applications.
Xiangkui Ren (2015)
Design of a novel fibronectin-mimetic peptide-amphiphile for functionalized biomaterials.
Anastasia Mardilovich (2006)
Electrospun scaffolds for stem cell engineering.
S. Lim (2009)
Role of metal ions in the self-assembly of the Alzheimer's amyloid-β peptide.
P. Faller (2013)
Self-assembly of elastin-mimetic double hydrophobic polypeptides.
Duc H. T. Le (2013)
Biomimetic Self-Templated Hierarchical Structures of Collagen-Like Peptide Amphiphiles.
Hyo-Eon Jin (2015)
Glycopolymer functionalization of engineered spider silk protein-based materials for improved cell adhesion.
John George Hardy (2014)
Energy landscapes and function of supramolecular systems
Faifan Tantakitti (2016)
Uncovering nanoscale electromechanical heterogeneity in the subfibrillar structure of collagen fibrils responsible for the piezoelectricity of bone.
Majid Minary-Jolandan (2009)
Robust, highly elastic and bioactive heparin-mimetic hydrogels
Chao He (2015)
Self-assembly of a peptide amphiphile based on hydrolysed Bombyx mori silk fibroin.
J. Zhang (2011)
Enzymatic activatable self-assembled peptide nanowire for targeted therapy and fluorescence imaging of tumors.
Y. Tang (2016)
Sequence Effects of Self-Assembling MultiDomain Peptide Hydrogels on Encapsulated SHED Cells
Marci K. Kang (2014)
Three-Dimensional Cell Entrapment as a Function of the Weight Percent of Peptide-Amphiphile Hydrogels.
C. M. Scott (2015)
Supramolecular Crafting of Self-Assembling Camptothecin Prodrugs with Enhanced Efficacy against Primary Cancer Cells
H. Su (2016)
Predictive modelling-based design and experiments for synthesis and spinning of bioinspired silk fibres.
S. Lin (2015)
Engineering aqueous fiber assembly into silk-elastin-like protein polymers.
Like Zeng (2014)
Angiogenic Heparin-Mimetic Peptide Nanofiber Gel Improves Regenerative Healing of Acute Wounds
Gozde Uzunalli (2017)
A Top-down Approach to Elucidate the Role of Matrix-Bound Phosphoproteins in Control of Collagen Biomineralization.
Alexander J. Lausch (2015)
Structural and functional features of a collagen-binding matrix protein from the mussel byssus.
M. Suhre (2014)
Small Peptides as Potent Mimetics of the Protein Hormone Erythropoietin
N. Wrighton (1996)
Biomimetic self-assembled nanofibers.
Ho-Wook Jun (2006)
Protein fibers as performance proteins: new technologies and applications.
T. Scheibel (2005)
AFM study of morphology and mechanical properties of a chimeric spider silk and bone sialoprotein protein for bone regeneration.
S. Gomes (2011)
Screening of integrin-binding peptides from the laminin α4 and α5 chain G domain peptide library.
Fumihiko Katagiri (2012)
Animal silks: their structures, properties and artificial production.
C. Fu (2009)
Designer nanomaterials using chiral self-assembling peptide systems and their emerging benefit for society.
Zhongli Luo (2012)
Fibronectin in tissue regeneration: timely disassembly of the scaffold is necessary to complete the build
J. Stoffels (2013)
Combination of integrin-binding peptide and growth factor promotes cell adhesion on electron-beam-fabricated patterns.
Christopher M. Kolodziej (2012)
Cooperative, reversible self-assembly of covalently pre-linked proteins into giant fibrous structures.
Saadyah E Averick (2014)
Fabrication of molecular materials using peptide construction motifs.
X. Zhao (2004)
Aligned macroscopic domains of optoelectronic nanostructures prepared via shear-flow assembly of peptide hydrogels.
Brian D. Wall (2011)
A fibronectin mimetic motif improves integrin mediated cell biding to recombinant spider silk matrices.
Mona Widhe (2016)
Fabrication of graphene–biomacromolecule hybrid materials for tissue engineering application
Dapeng Li (2017)
Mineralization of self-assembled peptide nanofibers for rechargeable lithium ion batteries.
J. Ryu (2010)
Bioinspired intrafibrillar mineralization of human dentine by PAMAM dendrimer.
J. Li (2013)
Self-assembly of protein fibrils into suprafibrillar aggregates: bridging the nano- and mesoscale.
S. Semerdzhiev (2014)
Protein aggregation kinetics, mechanism, and curve-fitting: a review of the literature.
A. Morris (2009)
Self-assembly of peptides to nanostructures.
D. Mandal (2014)
Injectable Peptide Decorated Functional Nanofibrous Hollow Microspheres to Direct Stem Cell Differentiation and Tissue Regeneration.
Z. Zhang (2015)
Nanocomposite gold-silk nanofibers.
Tzahi Cohen-Karni (2012)
Concepts and progress in the development of peptide mimetics.
G. L. Olson (1993)
Self-assembly of peptide-amphiphile nanofibers: the roles of hydrogen bonding and amphiphilic packing.
S. E. Paramonov (2006)
Heparin mimetic peptide nanofibers promote angiogenesis.
R. Mammadov (2011)
Self-assembled peptide nanofibers on graphene oxide as a novel nanohybrid for biomimetic mineralization of hydroxyapatite
J. Wang (2015)
Injectable multidomain peptide nanofiber hydrogel as a delivery agent for stem cell secretome.
E. Bakota (2011)
Self-assembled Tat nanofibers as effective drug carrier and transporter.
P. Zhang (2013)
Self-assembly of ovalbumin into amyloid and non-amyloid fibrils.
C. Lara (2012)
Effect of amino acid sequence and pH on nanofiber formation of self-assembling peptides EAK16-II and EAK16-IV.
Y. Hong (2003)
Self-assembly and hydrogelation of an amyloid peptide fragment.
M. Krysmann (2008)
Silk Nanofiber Hydrogels with Tunable Modulus to Regulate Nerve Stem Cell Fate.
S. Bai (2014)
Novel biopolymeric template for the nucleation and growth of hydroxyapatite crystals based on self-assembled fibrinogen fibrils.
G. Wei (2008)
Supramolecular nanostructures formed by anticancer drug assembly.
A. G. Cheetham (2013)
Improving pancreatic islet in vitro functionality and transplantation efficiency by using heparin mimetic peptide nanofiber gels.
G. Uzunalli (2015)
Detection of changes in near-membrane Ca2+ concentration using a novel membrane-associated Ca2+ indicator.
E. F. Etter (1994)
Self-assembly of fibronectin mimetic peptide-amphiphile nanofibers.
E. Rexeisen (2010)
Development and characterization of self-assembling nanoparticles using a bio-inspired amphipathic peptide for gene delivery.
H. McCarthy (2014)
Designer self-assembling peptide nanomaterials
Yang Yanlian (2009)
Design and engineering of silk fibroin scaffolds with biomimetic hierarchical structures.
H. Wang (2013)
Amyloids: not only pathological agents but also ordered nanomaterials.
Izhack Cherny (2008)
A multi-phase transitioning peptide hydrogel for suturing ultra-small vessels
D. Smith (2016)
Antitumor activity of peptide amphiphile nanofiber-encapsulated camptothecin.
S. Soukasene (2011)
Molecular self-assembly and applications of designer peptide amphiphiles.
X. Zhao (2010)
Functional Supramolecular Polymers
T. Aida (2012)
Cell interactions with the extracellular matrix
L. Bruckner-Tuderman (2009)
Mussel inspired dynamic cross-linking of self-healing peptide nanofiber network
H. Ceylan (2013)
A review of stimuli-responsive nanocarriers for drug and gene delivery.
Srinivas Ganta (2008)
Self-assembly of fiber-forming collagen mimetic peptides controlled by triple-helical nucleation.
Biplab Sarkar (2014)
Imaging dynamic insulin release using a fluorescent zinc indicator for monitoring induced exocytotic release (ZIMIR)
Daliang Li (2011)
Nanomechanical stimulus accelerates and directs the self-assembly of silk-elastin-like nanofibers.
Jonathan Chang (2011)
Nanomaterial-based activatable imaging probes: from design to biological applications.
Jingjing Li (2015)
Biocompatible fluorescent supramolecular nanofibrous hydrogel for long-term cell tracking and tumor imaging applications
Huaimin Wang (2015)
Designing peptide based nanomaterials.
R. Ulijn (2008)
Subtle charge balance controls surface-nucleated self-assembly of designed biopolymers.
Céline Charbonneau (2014)
Bimolecular based heparin and self-assembling hydrogel for tissue engineering applications.
Teresa Fernández-Muiños (2015)
Self-Assembling Peptide Nanofibrous Hydrogel as a Versatile Drug Delivery Platform.
Zhi-qiang Yu (2015)
Recent advances in self‐assembled peptides: Implications for targeted drug delivery and vaccine engineering
S. Eskandari (2017)
Controlled release of free doxorubicin from peptide-drug conjugates by drug loading.
Z. Chen (2014)
β‐Sheet and associated turn signatures in vibrational Raman optical activity spectra of proteins
Z. Wen (1994)
Development of bioactive peptide amphiphiles for therapeutic cell delivery.
M. Webber (2010)
Catalytic activity of copper ions in the amyloid fibrillation of β-lactoglobulin
Bruno Zappone (2013)
Slow release and delivery of antisense oligonucleotide drug by self-assembled peptide amphiphile nanofibers.
S. Bulut (2011)
Fibroblast Activation Protein, a Dual Specificity Serine Protease Expressed in Reactive Human Tumor Stromal Fibroblasts*
J. Park (1999)
Diverse Supramolecular Nanofiber Networks Assembled by Functional Low-Complexity Domains.
Bolin An (2017)
Bio-inspired in situ crosslinking and mineralization of electrospun collagen scaffolds for bone tissue engineering.
C. Dhand (2016)
Supramolecular Self-Assembly Bioinspired Synthesis of Luminescent Gold Nanocluster-Embedded Peptide Nanofibers for Temperature Sensing and Cellular Imaging.
Wensi Zhang (2017)
In vivo assessment of grafted cortical neural progenitor cells and host response to functionalized self-assembling peptide hydrogels and the implications for tissue repair.
A. L. Rodríguez (2014)
Crystal networks in silk fibrous materials: from hierarchical structure to ultra performance.
A. T. Nguyen (2015)
Self-assembled, photoluminescent peptide hydrogel as a versatile platform for enzyme-based optical biosensors.
J. Kim (2011)
Interplay between Intrinsic Conformational Propensities and Intermolecular Interactions in the Self-Assembly of Short Surfactant-like Peptides Composed of Leucine/Isoleucine.
P. Zhou (2016)
Self-assembly of protein-based biomaterials initiated by titania nanotubes.
Jacob H Forstater (2013)
Enhancement of neurite outgrowth using nano-structured scaffolds coupled with laminin.
H. S. Koh (2008)
Ultraviolet resonance Raman spectroscopy of a β‐sheet peptide: a model for membrane protein folding
H. S. Shafaat (2009)
Enhanced plastic deformations of nanofibrillated cellulose film by adsorbed moisture and protein-mediated interactions.
Jani-Markus Malho (2015)
Beaded nanofibers assembled from double‐hydrophobic elastin‐like block polypeptides: Effects of trifluoroethanol
Duc H. T. Le (2015)
Elastin-like polypeptides in drug delivery.
J. Rodríguez-Cabello (2016)
Elastin-like peptide amphiphiles form nanofibers with tunable length.
S. Aluri (2012)
Wet-spinning of amyloid protein nanofibers into multifunctional high-performance biofibers.
C. Meier (2011)
Strong underwater adhesives made by self-assembling multi-protein nanofibres.
C. Zhong (2014)
Self-assembling peptide and protein amyloids: from structure to tailored function in nanotechnology.
G. Wei (2017)
Peptide degradation is a critical determinant for cell-penetrating peptide uptake.
C. Palm (2007)
Programmable Assembly of Peptide Amphiphile via Noncovalent-to-Covalent Bond Conversion
K. Sato (2017)
Antitumor potential of a synthetic interferon-alpha/PLGF-2 positive charge peptide hybrid molecule in pancreatic cancer cells
H. Yin (2015)
Hydroxyapatite-containing silk fibroin nanofibrous scaffolds for tissue-engineered periosteum
Xili Ding (2016)
One-Dimensional Peptide Nanostructure Templated Growth of Iron Phosphate Nanostructures for Lithium-Ion Battery Cathodes.
Hepi Hari Susapto (2016)
Biomimetic and Bioinspired Synthesis of Nanomaterials/Nanostructures.
Guangtao Zan (2016)
Co-assembly, spatiotemporal control and morphogenesis of a hybrid protein-peptide system.
Karla E. Inostroza-Brito (2015)
Emerging biological materials through molecular self-assembly.
S. Zhang (2002)
Preparation of mineralized nanofibers: collagen fibrils containing calcium phosphate.
M. Maas (2011)
Peptide and protein mimetics inhibiting amyloid beta-peptide aggregation.
T. Takahashi (2008)
Applications of combinatorial technologies to drug discovery. 1. Background and peptide combinatorial libraries.
M. Gallop (1994)
Molecular biomimetics: nanotechnology through biology
M. Sarikaya (2003)
ATR-FTIR: a "rejuvenated" tool to investigate amyloid proteins.
Rabia Sarroukh (2013)
Bioinspired structural materials.
U. Wegst (2015)
Cell-penetrating peptides: design, synthesis, and applications.
D. Copolovici (2014)
Stimuli-responsive nanocarriers for drug delivery.
S. Mura (2013)
Temperature-sensitive elastin-mimetic dendrimers: Effect of peptide length and dendrimer generation to temperature sensitivity.
Chie Kojima (2014)
Fibronectin fibrillogenesis on sulfonated polystyrene surfaces.
N. Pernodet (2003)
Nanofibrous heparin and heparin-mimicking multilayers as highly effective endothelialization and antithrombogenic coatings.
Chuanxiong Nie (2015)
Tunable Fabrication of Molybdenum Disulfide Quantum Dots for Intracellular MicroRNA Detection and Multiphoton Bioimaging.
Wenhao Dai (2015)
8DSS-promoted remineralization of demineralized dentin in vitro.
Kunneng Liang (2015)
Designer self-assembling peptide nanofiber biological materials.
C. A. Hauser (2010)
Fibroblast-activation protein: a single marker that confidently differentiates morpheaform/infiltrative basal cell carcinoma from desmoplastic trichoepithelioma
O. Abbas (2010)
Peptide synthesis in aqueous environments: the role of extreme conditions on peptide bond formation and peptide hydrolysis.
E. Schreiner (2009)
Transformable Peptide Nanocarriers for Expeditious Drug Release and Effective Cancer Therapy via Cancer‐Associated Fibroblast Activation
T. Ji (2016)
Novel 1-D biophotonic nanohybrids: protein nanofibers meet quantum dots
Gang Wei (2011)
Aqueous multiphoton lithography with multifunctional silk-centred bio-resists
Yun-Lu Sun (2015)
Nanostructures from the self‐assembly of α‐helical peptide amphiphiles
Qingbin Meng (2014)
Bioactive Nanofiber Matrices Functionalized with Fibronectin‐Mimetic Peptides Driving the Alignment and Tubular Commitment of Adult Renal Stem Cells
A. Sciancalepore (2016)
Angiogenic peptide nanofibers repair cardiac tissue defect after myocardial infarction.
A. J. Rufaihah (2017)
I. Capila (2002)
Multifunctional adhesive silk fibroin with blending of RGD-bioconjugated mussel adhesive protein.
Y. J. Yang (2014)
Self-assembly of short collagen-related peptides into fibrils via cation-π interactions.
Chia-Ching Chen (2011)
Graphene-based wireless bacteria detection on tooth enamel.
M. S. Mannoor (2012)
Fibronectin-mimetic peptide-amphiphile nanofiber gels support increased cell adhesion and promote ECM production
Kamlesh Shroff (2010)
Design, fabrication, and biomedical applications of bioinspired peptide-inorganic nanomaterial hybrids.
Xiaoqing Yu (2017)
Controlled release of dexamethasone from peptide nanofiber gels to modulate inflammatory response.
M. Webber (2012)
Accumulation of Dynamic Catch Bonds between TCR and Agonist Peptide-MHC Triggers T Cell Signaling
B. Liu (2014)
Double-Chambered Ferritin Platform: Dual-Function Payloads of Cytotoxic Peptides and Fluorescent Protein.
S. Kim (2016)
Programming pH-triggered self-assembly transitions via isomerization of peptide sequence.
A. Ghosh (2014)
Heparin mimetic peptide nanofiber gel promotes regeneration of full thickness burn injury.
Fatih Yergoz (2017)
Effects of peptide ratios in nanofibre‐based hydrogels for the prevention of capsular opacification
Lisanne M. Nibourg (2016)
A modular electrochemical peptide-based sensor for antibody detection.
Mihaela Puiu (2014)
Molecular mechanisms for intrafibrillar collagen mineralization in skeletal tissues.
Zhijun Xu (2015)
Self-assembling peptide amphiphile nanofiber matrices for cell entrapment.
E. Beniash (2005)
Motif-designed peptide nanofibers decorated with graphene quantum dots for simultaneous targeting and imaging of tumor cells
Z. Su (2015)
Directed Growth of Silk Nanofibrils on Graphene and Their Hybrid Nanocomposites
Shengjie Ling (2014)
TDP6, a brain-derived neurotrophic factor-based trkB peptide mimetic, promotes oligodendrocyte myelination
A. W. Wong (2014)
Amyloid-carbon hybrid membranes for universal water purification.
Sreenath Bolisetty (2016)
Distinct β-sheet structure in protein aggregates determined by ATR-FTIR spectroscopy.
Bhavana Shivu (2013)
Use of thiolated oligonucleotides as anti-fouling diluents in electrochemical peptide-based sensors.
Adam McQuistan (2014)
Examination of the secondary structure of proteins by deconvolved FTIR spectra
D. Byler (1986)
Self-assembled peptide nanofiber templated one-dimensional gold nanostructures exhibiting resistive switching.
H. Acar (2012)
Mimicry of bioactive peptides via non-natural, sequence-specific peptidomimetic oligomers.
J. Patch (2002)
The bioactivity of composite Fmoc-RGDS-collagen gels.
Ricardo M Gouveia (2014)
Growth factor binding on heparin mimetic peptide nanofibers.
R. Mammadov (2012)
Self-Assembly of Tetraphenylalanine Peptides.
Enric Mayans (2015)
Amyloid inspired self-assembled peptide nanofibers.
Goksu Cinar (2012)
Multifunctional materials through modular protein engineering.
Rebecca L DiMarco (2012)
Nanoparticle Formation from Hybrid, Multiblock Copolymers of Poly(Acrylic Acid) and VPGVG Peptide.
Sarah E. Grieshaber (2013)
Self-Assembled Collagen-like Peptide Fibers as Templates for Metallic Nanowires.
Daniel Gottlieb (2008)
A Tumor Targeted Chimeric Peptide for Synergistic Endosomal Escape and Therapy by Dual‐Stage Light Manipulation
K. Han (2015)
Analysis of insulin amyloid fibrils by Raman spectroscopy.
C. Ortiz (2007)
Bioinspired self-assembled peptide nanofibers with thermostable multivalent α-helices.
So-hee Han (2013)
Hybrid nanocomposites of gold single-crystal platelets and amyloid fibrils with tunable fluorescence, conductivity, and sensing properties.
C. Li (2013)
The self-assembly, aggregation and phase transitions of food protein systems in one, two and three dimensions.
R. Mezzenga (2013)
Designed amyloid fibers as materials for selective carbon dioxide capture
D. Li (2013)
Self-assembling glucagon-like peptide 1-mimetic peptide amphiphiles for enhanced activity and proliferation of insulin-secreting cells.
S. Khan (2012)
The structure of α-helical coiled coils
A. Lupas (2005)
Basal Lamina Mimetic Nanofibrous Peptide Networks for Skeletal Myogenesis
Immihan Ceren Yasa (2015)
Peptide Bioink: Self-Assembling Nanofibrous Scaffolds for Three-Dimensional Organotypic Cultures.
Yihua Loo (2015)
Electrostatic Assembly of Peptide Nanofiber–Biomimetic Silver Nanowires onto Graphene for Electrochemical Sensors
Jinhui Wang (2014)
The position of hydrophobic residues tunes peptide self-assembly.
Christian Bortolini (2014)
Synthesis and in vitro hydroxyapatite binding of peptides conjugated to calcium-binding moieties.
Matthew B. Murphy (2007)
Heat-generating iron oxide nanocubes: subtle "destructurators" of the tumoral microenvironment.
Jelena Kolosnjaj-Tabi (2014)
Bioactive supramolecular peptide nanofibers for regenerative medicine.
E. Arslan (2014)
Directed patterning of the self-assembled silk-elastin-like nanofibers using a nanomechanical stimulus.
S. Johnson (2012)
Collagen-Based Artificial Corneal Scaffold with Anti-Infective Capability for Prevention of Perioperative Bacterial Infections
A. Riau (2015)
Amyloid-derived peptide forms self-assembled monolayers on gold nanoparticle with a curvature-dependent β-sheet structure.
C. P. Shaw (2012)
Bioactive self-assembled peptide nanofibers for corneal stroma regeneration.
G. Uzunalli (2014)
Sequence, structure, and function of peptide self-assembled monolayers.
Ann K. Nowinski (2012)
Bottom-Up Synthesis and Sensor Applications of Biomimetic Nanostructures
L. Wang (2016)
Dissecting Electrostatic Contributions to Folding and Self-Assembly Using Designed Multicomponent Peptide Systems.
A. Parmar (2016)
The robust hydrogel hierarchically assembled from a pH sensitive peptide amphiphile based on silk fibroin.
H. Guo (2013)
Protein-Coupled Fluorescent Probe To Visualize Potassium Ion Transition on Cellular Membranes.
Tomoya Hirata (2016)
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M. Ding (2019)
Electrohydrodynamic Jet Printing – Principles and Applications in High Sensitivity Biosensing
Gaofeng Zheng (2020)
Removing Metal Ions from Water with Graphene–Bovine Serum Albumin Hybrid Membrane
X. Yu (2019)
Opportunities, Challenges, and Prospects in Electrochemical Biosensing of Circulating Tumor DNA and Its Specific Features
Susana Campuzano (2019)
Mineralization of calcium phosphate controlled by biomimetic self-assembled peptide monolayers via surface electrostatic potentials
Shuo Wang (2020)
Current progress in application of polymeric nanofibers to tissue engineering
Sorour Nemati (2019)
Coupling synthetic biology and programmable materials to construct complex tissue ecosystems.
Catherine S Millar-Haskell (2019)
Dentin Phosphoprotein Mimetic Peptide Nanofibers Promote Biomineralization.
Gulcihan Gulseren (2019)
Building switchable peptide-architectures on gold/composite surfaces: New perspectives in electrochemical bioassays
Mihaela Puiu (2018)
Graphene oxide nanofilm and the addition of l-glutamine can promote development of embryonic muscle cells
M. Zielińska-Górska (2020)
Nanostructure-based photoelectrochemical sensing platforms for biomedical applications.
Zhenli Qiu (2020)
Effect of Silk Fibroin on Cell Viability in Electrospun Scaffolds of Polyethylene Oxide
Gabriela Carrasco-Torres (2019)
Interactions between elastin-like peptides and an insulating poly(ortho-aminophenol) membrane investigated by AFM and XPS
M. E. Carbone (2018)
Enhanced Mechanical Properties of Poly(arylene sulfide sulfone) Membrane by Co-electrospinning with Poly(m-xylene adipamide)
L. Chen (2020)
Hierarchical nanomaterials via biomolecular self-assembly and bioinspiration for energy and environmental applications.
Coucong Gong (2019)
Using Self-Assembling Peptides to Integrate Biomolecules into Functional Supramolecular Biomaterials
Renjie Liu (2019)
Developing Graphene-Based Nanohybrids for Electrochemical Sensing.
H. Song (2019)
Multilevel structural stereocomplex polylactic acid/collagen membranes by pattern electrospinning for tissue engineering
Y. Kang (2018)
Graphene oxide nanofilm and the addition of l-glutamine can promote development of embryonic muscle cells
M. Zielińska-Górska (2020)
Modulation of structure and mechanical properties of self-assembled peptide nanofibrils and nanosheets
Hangshuai Jin (2019)
Biotinylated and fluorophore-incorporated polymeric mixed micelles for tumor cell-specific turn-on fluorescence imaging of Al3.
Caixia Wang (2019)
Self-assembled thermosensitive luminescent nanoparticles with peptide-Au conjugates for cellular imaging and drug delivery
Xiaoyuan Zhang (2020)
Functional Peptide Nanofibers with Unique Tumor Targeting and Enzyme-Induced Local Retention Properties.
Vanessa Bellat (2018)
Enzyme-based hybrid nanoflowers with high performances for biocatalytic, biomedical, and environmental applications
Yiduo Li (2020)
Biomolecule conjugated metal nanoclusters: bio-inspiration strategies, targeted therapeutics, and diagnostics.
S. Zhang (2020)
Recent progresses in graphene based bio-functional nanostructures for advanced biological and cellular interfaces
Chuanxiong Nie (2019)
NIR light-responsive short peptide/2D NbSe2 nanosheets composite hydrogel with controlled-release capacity
Can Wu (2019)
Targeting self-assembly peptide for inhibiting breast tumor progression and metastasis.
S. Luo (2020)
Enhance transgene responses through improving cellular uptake and intracellular trafficking by bio-inspired non-viral vectors
Xi-Xi Ma (2020)
A Review on Properties of Natural and Synthetic Based Electrospun Fibrous Materials for Bone Tissue Engineering
Deval Prasad Bhattarai (2018)See more