Online citations, reference lists, and bibliographies.
Please confirm you are human
(Sign Up for free to never see this)
← Back to Search

Electrochemiluminescence Performance Of Nitroolefin-based Fluorescein In Different Solutions And Its Application For The Detection Of Cysteine

Hangqing Xie, X. Li, Linlin Zhao, L. Han, Wenbo Zhao, X. Chen
Published 2016 · Chemistry

Save to my Library
Download PDF
Analyze on Scholarcy
Abstract Electrochemiluminescence (ECL) property of nitroolefin-based fluorescein was investigated and reported for the first time. Its ECL behaviors in acetonitrile (CH 3 CN) system and aqueous system were studied, respectively. Results indicated that nitroolefin-based fluorescein showed reversible reduction peaks on cycling voltammetric (CV) spectrum and produced ECL emission with the presence of benzoyl peroxide (BPO) as a coreactant in CH 3 CN solution. Reduction potential peaks of the substance can be observed in water solution in CV, and the intensity of ECL emission is much lower in water than that of in CH 3 CN solution. However, the ECL property of nitroolefin-based fluorescein can be used for the detection of cysteine (Cys) by using potassium persulfate (K 2 S 2 O 8 ) as coreactant in aqueous solution. Under optimum conditions, the ECL intensity has a linear relationship with the concentration of cysteine in the range of 10 −9 to 10 −8 mol L −1 and a detection limit of 4.2 × 10 −10 mol L −1 . It has a lower detection limit than the fluorescence method. Our investigation demonstrated that the proposed method provides an elegant platform for fabrication of new generation of biosensors with ultrahighsensitivity, and might have potentially broad applications in amino acids diagnostics and bioassay.
This paper references
Tuning the electrochemiluminescence potential from immobilised BODIPY by co-reactant selection
A. Venkatanarayanan (2013)
Recent progress in luminescent and colorimetric chemosensors for detection of thiols.
H. S. Jung (2013)
Electrochemiluminescence properties of a carboxy functionalised BODIPY
A. Venkatanarayanan (2012)
A fluorescent sensor bearing nitroolefin moiety for the detection of thiols and its biological imaging
Huilin Wang (2013)
Development of the Colle-Salvetti correlation-energy formula into a functional of the electron density.
Lee (1988)
Fluorescent and luminescent probes for detection of reactive oxygen and nitrogen species.
Xiaoqiang Chen (2011)
Synthesis, Photophysics, Electrochemistry and Electrogenerated Chemiluminescence of PEG-Modified BODIPY dyes in Organic and Aqueous Solutions.
A. B. Nepomnyashchii (2013)
Electrogenerated chemiluminescence of nanomaterials for bioanalysis.
Shengyuan Deng (2013)
Electrochemistry and electrogenerated chemiluminescence of π-stacked poly(fluorenemethylene) oligomers. Multiple, interacting electron transfers.
H. Qi (2012)
Electrogenerated Chemiluminescence of ZnS Nanoparticles in Alkaline Aqueous Solution
Lihua Shen (2007)
Green electrogenerated chemiluminescence of highly fluorescent benzothiadiazole and fluorene derivatives.
K. Omer (2009)
Results obtained with the correlation energy density functionals of becke and Lee, Yang and Parr
B. Miehlich (1989)
Electrogenerated chemiluminescence of solutions, films, and nanoparticles of dithienylbenzothiadiazole-based donor-acceptor-donor red fluorophore. Fluorescence quenching study of organic nanoparticles.
Mei Shen (2013)
Electrochemiluminescence immunosensor based on CdSe nanocomposites.
Guifen Jie (2008)
Electrogenerated chemiluminescence of Au nanoclusters for the detection of dopamine.
L. Li (2011)
Graphene oxide amplified electrogenerated chemiluminescence of quantum dots and its selective sensing for glutathione from thiol-containing compounds.
Ying Wang (2009)
Luminescent chemodosimeters for bioimaging.
Y. Yang (2013)
Biosensors and chemosensors based on the optical responses of polydiacetylenes.
Xiaoqiang Chen (2012)
Electrochemistry and Electrogenerated Chemiluminescence from Silicon Nanocrystal Quantum Dots
Z. Ding (2002)
CdS nanocrystal-based electrochemiluminescence biosensor for the detection of low-density lipoprotein by increasing sensitivity with gold nanoparticle amplification.
G. Jie (2007)
Zebrafish as a good vertebrate model for molecular imaging using fluorescent probes.
Sung-Kyun Ko (2011)
Density-functional thermochemistry. III. The role of exact exchange
Axel D. Becke (1993)
Detection of homocysteine and cysteine.
Weihua Wang (2005)

This paper is referenced by
An effective signal enhancement strategy for sensing cysteine based on aluminium-initiated emission
Wu Zou (2017)
A highly water-soluble, sensitive, coumarin-based fluorescent probe for detecting thiols, and its application in bioimaging
L. Guo (2017)
Stimulus-responsive electrochemiluminescence from self-assembled block copolymer and nonpolar carbon quantum dot composite nanospheres
Hangqing Xie (2019)
A coumarin-based fluorescent probe for thiols and its application in cell imaging
Y. Liao (2016)
A highly sensitive fluorescent probe based on the Michael addition mechanism with a large Stokes shift for cellular thiols imaging
S. Chen (2018)
Electrochemiluminescent sensors as a screening strategy for psychoactive substances within biological matrices.
Kelly Brown (2020)
Electrochemiluminescent Chemosensors for Clinical Applications: A Review
Cuong Khac Phu Truong (2019)
A polymer-based probe for specific discrimination of cysteine.
K. Liu (2017)
A novel fluorescent probe for highly sensitive and selective detection of cysteine and its application in cell imaging
Yuewen Yu (2017)
Psychoactive substances and how to find them : electrochemiluminescence as a strategy for identification and differentiation of drug species
Kelly Brown (2020)
A dual-mode probe for colorimetric and fluorometric detection of cysteine based on phosphorus/nitrogen co-doped CQDs and gold nanorods
Y. Wang (2018)
Semantic Scholar Logo Some data provided by SemanticScholar