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Synthetic Studies Towards Zetekitoxin AB: Preparation Of 4,5-epi-11-hydroxy-saxitoxinol.

A. D. Pearson, R. M. Williams
Published 2014 · Chemistry, Medicine

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A concise synthesis of 4,5-epi-11-hydroxy-saxitoxinol utilizing D-ribose to direct an asymmetric Mannich reaction. This approach allows many modes of reactivity, which can be used to access various analogs of saxitoxin.
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