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Highly Efficient And Economic Synthesis Of New Substituted Amino-bispyridyl Derivatives Via Copper And Palladium Catalysis

S. Gaillard, M. K. Elmkaddem, C. Fischmeister, C. Thomas, J. Renaud
Published 2008 · Chemistry

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A convenient route for the synthesis of a variety of amino-bispyridyl compounds is introduced. Bispyridylamines were prepared in three steps from commercially available 2,6-dibromopyridine, via a copper mediated alkylation followed by two consecutive N-arylation reactions catalyzed by copper and palladium, respectively.
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