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Electrochemical Immunosensors: Critical Survey Of Different Architectures And Transduction Strategies

Christos Kokkinos, A. Economou, M. Prodromidis
Published 2016 · Computer Science

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Abstract This review describes the most popular architectures and transduction strategies that have been proposed for the development of electrochemical immunosensors. Relative published work has been classified into four main categories: i) enzyme-labelled immunosensors, ii) metal nanoparticle- and quantum dot-labelled immunosensors, iii) capacitive and (faradic) impedimetric immunosensors, and iv) magnetoimmunosensors. The principle of operation, analytical features, various signal amplification strategies as well as the adaptability of the afore-mentioned types of immunosensors to multiplexed formats, (micro) fluidic platforms and paper-based approaches are critically discussed. Perspectives in point-of-care analysis and commercialization opportunities are also discussed.
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