Online citations, reference lists, and bibliographies.
← Back to Search

Outcome Of Protein-energy Malnutrition In Elderly Medical Patients.

T. Cederholm, C. Jägrén, K. Hellström
Published 1995 · Medicine

Save to my Library
Download PDF
Analyze on Scholarcy Visualize in Litmaps
Share
Reduce the time it takes to create your bibliography by a factor of 10 by using the world’s favourite reference manager
Time to take this seriously.
Get Citationsy
PURPOSE To assess the impact of protein-energy malnutrition (PEM) on mortality and the long-term variations in the nutritional status of subjects admitted as emergency cases in a 9-month prospective follow-up study. PATIENTS AND METHODS The study comprised 205 patients without cancer aged 75 years (+/- 1). Malnourished subjects were identified as having at least three nutritional variables (which included weight index, triceps skinfold thickness, arm muscle circumference, serum albumin, and delayed cutaneous hypersensitivity reaction) below the reference range. RESULTS The mortality was 44% in the 41 malnourished patients and 18% in the 164 nonmalnourished subjects (P < 0.001). Among malnourished patients with congestive heart failure the mortality was 80%. Multivariate analysis revealed congestive heart failure, multiple organ disease, and PEM to be predictors of death. When the interaction between these disorders and PEM was considered, the prognostic relevance of PEM remained among the patients with cardiac congestion. Of the surviving subjects, 125 were reexamined after 9 months. At admission, more than half of the patients had displayed elevated levels of serum acid glycoprotein as evidence of an ongoing inflammation and subnormal recordings for serum albumin and delayed cutaneous hypersensitivity. At the reexamination, these variables had normalized in the well-nourished patients and in the 9 patients who had recovered from PEM, but remained unchanged in the 10 patients with persistent PEM. The latter patients were severely malnourished, commonly infected, and often hospitalized. CONCLUSIONS Protein-energy malnutrition in noncancer medical patients is associated with an excess mortality in those with congestive heart failure. Improvement of PEM is accompanied by a decline in inflammatory activity.
This paper references
10.1001/JAMA.1936.02770060032009
PERCENTAGE OF WEIGHT LOSS: BASIC INDICATOR OF SURGICAL RISK IN PATIENTS WITH CHRONIC PEPTIC ULCER
Hiram O. Studley (1936)
10.1177/028418513902000401
A Method for the Determination of the Heart Size by Teleroentgenography (A Heart Volume Index)
S. Jonsell (1939)
10.1136/bmj.1.5271.67
The Heart in Kwashiorkor
P. Smythe (1964)
10.1016/s0899-9007(97)83027-4
The assessment of the nutritional status of the community.
D. Jelliffe (1966)
10.1159/000166102
Nutrition and the heart.
V. Ramalingaswami (1968)
10.1177/014860717700100101
Nutritional and metabolic assessment of the hospitalized patient.
G. Blackburn (1977)
10.1016/S0022-5223(19)39884-8
Nutritional support in cardiac cachexia.
G. Blackburn (1977)
Energy and protein intake in elderly patients in an orthopedic surgical ward.
I. Hessov (1977)
10.1016/0002-8703(78)90300-9
Cardiac abnormalities in cachectic patients before and during nutritional repletion.
S. Heymsfield (1978)
10.1016/S0022-5223(19)38263-7
Nutritional status of patients requiring cardiac surgery.
R. Walesby (1979)
10.1177/014860718000400404
Incidence and mortality of hypoalbuminemic patients in hospitalized veterans.
G. Reinhardt (1980)
10.1016/S0039-6109(16)42442-4
Nutritional support in cardiac failure.
S. Heymsfield (1981)
10.1080/07315724.1982.10718069
The correctability of the nutritional, immune, and hematopoietic manifestations of protein calorie malnutrition in the elderly.
D. Lipschitz (1982)
10.1093/ajcn/35.2.417
Single nutrients and immunity.
W. Beisel (1982)
10.1097/00003246-198205000-00003
Comparison of nutritional indices and outcome in critically ill patients
K. Apelgren (1982)
10.1016/0261-5614(82)90015-2
Arm anthropometry in a large reference population and in surgical patients.
T. Symreng (1982)
10.1111/J.0954-6820.1982.TB03188.X
Nutritional status of medical patients on emergency admission to hospital.
N. Albiin (1982)
10.1177/0148607182006003218
Instant nutritional assessment: absolute weight loss and surgical mortality.
M. Seltzer (1982)
10.1177/014860718200600150
Utility of skin testing in nutritional assessment: a critical review.
P. Twomey (1982)
10.1016/0261-5614(83)90004-3
Delayed hypersensitivity. A critical evaluation of five recall antigens in a large reference population.
T. Symreng (1983)
10.1097/00000658-198403000-00009
Clinical Significance of Preoperative Nutritional Status in 215 Noncancer Patients
I. Warnold (1984)
10.1093/AJCN/39.1.66
Outcomes of older and younger malnourished and well-nourished patients one year after hospitalization.
B. Linn (1984)
10.1016/S0140-6736(85)91447-3
INCREASED VASCULAR PERMEABILITY: A MAJOR CAUSE OF HYPOALBUMINAEMIA IN DISEASE AND INJURY
A. Fleck (1985)
10.1093/AGEING/15.1.53
Grip strength, mental performance and nutritional status as indicators of mortality risk among female geriatric patients.
P. Phillips (1986)
Surg Clin North Am.
Rg. Martin (1986)
10.1177/0148607187011004360
Relation of serum albumin concentration to death rate in nursing home men.
D. Rudman (1987)
10.1093/AGEING/16.1.73
Hospital nutrition in geriatric long-term care medicine: II. Effects of dietary supplements.
S. Elmståhl (1987)
10.1093/AJCN/48.5.1173
Predictive ability of various nutritional variables for mortality in elderly people.
N. Agarwal (1988)
10.1016/0261-5614(88)90022-2
The evaluation of nutritional status in general medical patients
A. Rodríguez-González (1988)
10.1016/0002-9149(89)90256-7
Prevalence and hemodynamic correlates of malnutrition in severe congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy.
J. Carr (1989)
10.1177/014860718901300130
Hand grip dynamometry as a predictor of postoperative complications reappraisal using age standardized grip strengths.
A. Webb (1989)
10.1097/00003246-198908000-00004
Relationship of visceral proteins to nutritional status in chronic and acute stress.
M. Boosalis (1989)
Functional decline and nutritional status in a hospitalized geriatric population: sequential study.
P. Morales-Rodriguez (1990)
10.1056/NEJM199007263230405
Elevated circulating levels of tumor necrosis factor in severe chronic heart failure.
B. Levine (1990)
10.1016/0261-5614(90)90017-M
Effect of dietary supplement on nutritional status and clinical outcome in 501 geriatric patients--a randomised study.
J. Larsson (1990)
10.2307/2348743
Applied Logistic Regression.
R. Iyer (1991)
10.1177/0148607191015004400
A prospective study of outcome from protein-energy malnutrition in nursing home residents.
D. R. Thomas (1991)
10.1159/000213314
Nutritional status in recently hospitalized and free-living elderly subjects.
T. Cederholm (1992)
10.1016/0261-5614(92)90056-V
TNF and other cytokines in the metabolism of septic shock and cachexia.
K. Tracey (1992)
10.1016/0261-5614(93)90138-T
Nutritional status and performance capacity in internal medical patients.
T. Cederholm (1993)
10.2307/2074954
Applied Logistic Regression.
S. Gortmaker (1994)



This paper is referenced by
10.1186/s12877-021-02068-2
Factors associated with the nutritional status of the older population in a selected area of Dhaka, Bangladesh
K. M. Rahman (2021)
10.1016/j.jfma.2020.05.007
Derivation and validation of a new nutritional index for predicting 90 days mortality after ICU admission in a Korean population.
Da-Hye Son (2020)
10.1007/978-3-030-42667-5
Reviews on New Drug Targets in Age-Related Disorders
P. Guest (2020)
10.1007/978-3-030-42667-5_12
The Role of Nutrition in Attenuating Age-Related Skeletal Muscle Atrophy.
Behnaz Abiri (2020)
10.1177/0300060519863497
Correlation between malnutrition and health-related quality of life (HRQOL) in elderly Iranian adults
F. Khatami (2019)
10.1007/978-3-662-54507-2_107
Anästhesie bei Patienten mit schwerer Mangelernährung
Thomas W. Felbinger (2019)
10.11244/EJSPEN.1.1_13
出雲地域における在宅NST(Nutrition Support Team)活動とその介入効果
真美 中山 (2019)
10.1016/j.clnesp.2019.02.010
Malnutrition predicts long-term survival in hospitalized patients with gastroenterological and hepatological diseases.
B. Knappe-Drzikova (2019)
10.1108/BFJ-06-2017-0358
Older adults involvement in developing satisfactory pasta sauces with healthy ingredients
S. Predieri (2018)
10.1002/jpen.1042
Characteristics and Outcomes of Adult Inpatients With Malnutrition
M. Vest (2018)
Risk of Aminoglycoside-Induced Hearing Loss among Patients with Drug-Resistant Tuberculosis in South Africa
Hyejeong Hong (2018)
Money can buy me life. The Effect of a Basic Pension on Mortality: a Regression Discontinuity Design
Enrico Miglino (2018)
Technological Developments for Producing Soft Meat that Retains its Original Shape and can be Preserved at Room Temperature
Aya Nakajima (2018)
10.1177/0148607116676592
Malnutrition at Intensive Care Unit Admission Predicts Mortality in Emergency General Surgery Patients
J. Havens (2018)
10.3389/fnut.2017.00050
Malnutrition upon Hospital Admission in Geriatric Patients: Why Assess It?
P. Orlandoni (2017)
Chapter 70 The Geriatric Patient
Carl W. Peters (2017)
10.24884/0042-4625-2017-176-1-60-64
RESULTS OF ENHANCED RECOVERY PROTOCOL IN GERONTOLOGICAL PATIENS WITH COLON CANCER
G. M. Manikhas (2017)
10.1016/j.jstrokecerebrovasdis.2017.02.020
Transthyretin Concentrations in Acute Stroke Patients Predict Convalescent Rehabilitation.
N. Isono (2017)
10.23937/2572-3278.1510021
Exploration of Nutrition Support Team Outcome Predictors for Elderly
M. Hiramatsu (2017)
10.1111/ger.12290
The relationship between periodontal disease, tooth loss and decreased skeletal bone mineral density in ageing women
I. Savić Pavičin (2017)
10.1016/j.clnu.2016.06.019
Geriatric nutritional risk index correlates with length of hospital stay and inflammatory markers in older inpatients.
Simone Gärtner (2017)
10.2152/jmi.64.140
Impact of a multidisciplinary rehabilitation nutrition team on evaluating sarcopenia, cachexia and practice of rehabilitation nutrition.
Y. Kokura (2017)
10.1186/s12879-016-1718-5
Convergence of a diabetes mellitus, protein energy malnutrition, and TB epidemic: the neglected elderly population
S. Menon (2016)
10.1016/j.ccm.2016.01.006
Beyond the Golden Hours: Caring for Septic Patients After the Initial Resuscitation.
J. Gelinas (2016)
Undernutrition in hospitals
M. Holst (2016)
10.17116/hirurgia20161237-41
[Enhanced recovery protocol in gerontological colon cancer patients].
G. N. Khrykov (2016)
10.1016/j.jamda.2016.08.009
Impacts of High-Protein Oral Nutritional Supplements Among Malnourished Men and Women with Sarcopenia: A Multicenter, Randomized, Double-Blinded, Controlled Trial.
J. Cramer (2016)
10.1016/J.JCE.2016.12.002
The Health Implications of Social Pensions: Evidence from China's New Rural Pension Scheme
L. Cheng (2016)
10.1016/j.amjcard.2016.05.015
Application of a Multidisciplinary Enhanced Recovery After Surgery Pathway to Improve Patient Outcomes After Transcatheter Aortic Valve Implantation.
Michael Sola (2016)
10.1111/1750-3841.13298
Development of a Drinkable, Peanut-Based Dietary Supplement and Comparison of Its Nutritional and Microbiological Qualities with Commercial Products.
Y. A. Klu (2016)
10.1590/1677-5449.001215
Evidências para o uso da avaliação nutricional subjetiva global nos pacientes com doença arterial periférica
L. Costa (2016)
10.2186/AJPS.8.113
National Management Linking Acute Medical Phase to Home Care and Life Support
T. Higashiguchi (2016)
See more
Semantic Scholar Logo Some data provided by SemanticScholar