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Initial Glaucomatous Optic Disk And Retinal Nerve Fiber Layer Abnormalities And Their Progression.

A. Tuulonen, P. Airaksinen
Published 1991 · Medicine

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We attempted to identify the initial glaucomatous changes of the optic disk and retinal nerve fiber layer and to analyze how these changes subsequently progressed. Of 61 eyes of 61 patients with ocular hypertension, 23 (38%) developed glaucoma during ten years of follow-up (range, five to 15 years). The initial sign of glaucomatous damage was diffuse enlargement of the optic disk cup in ten of 23 eyes or generalized thinning of the nerve fiber layer without localized changes in 12 of 23 eyes. We found localized optic disk damage in ten of 23 patients and localized retinal nerve fiber layer damage in 11 of 23 patients alone or in combination with diffuse damage. In 13 of 23 eyes, the cupping ended up in diffuse enlargement with even more profound thinning of the neural rim in the upper and lower temporal disk margins. There seems to be great variability in the appearance and progression of the initial glaucomatous optic disk and nerve fiber layer abnormalities in patients with increased intraocular pressure.
This paper references

This paper is referenced by
23 – Measuring Glaucoma Progression in Clinical Practice
Brian J. Song (2015)
Event-based progression detection strategies using scanning laser polarimetry images of the human retina
K. A. Vermeer (2011)
European Glaucoma Society Terminology and Guidelines for Glaucoma, 4th Edition - Part 1Supported by the EGS Foundation
T. Square (2017)
Neuroprotection in relation to retinal ischemia and relevance to glaucoma.
N. Osborne (1999)
Retinal nerve fiber layer imaging with spectral-domain optical coherence tomography: a variability and diagnostic performance study.
C. Leung (2009)
Optic disk appearance in ocular hypertensive eyes.
J. Jonas (1994)
Diagnostic ability of Heidelberg Retina Tomograph 3 classifications: glaucoma probability score versus Moorfields regression analysis.
A. Ferreras (2007)
A non-linear multivariable regression method for the investigation of the correlation between central corneal thickness and HRTII optic nerve head topographic measurements in glaucoma patients
D. Kourkoutas (2008)
Ophthalmoscopic evaluation of the optic nerve head.
J. Jonas (1999)
Structural evaluation of preperimetric and perimetric glaucoma
G. Deshpande (2019)
Localized Retinal Nerve Fiber Layer Defects in Red-free Photographs Versus En Face Structural Optical Coherence Tomography Images
J. H. Jung (2018)
Evaluation of retinal nerve fiber layer thickness and optic nerve head changes in early to moderate glaucoma patients and compare them with age matched individuals using spectral domain optical coherence tomography
P. K. S. Suvitha (2013)
Glaucoma update: epidemiology and new approaches to medical management.
J. Flanagan (1998)
A new classification of glaucoma including focal glaucoma.
G. Spaeth (1994)
Quantitative evaluation of the optic nerve head in early glaucoma
D. Garway-Heath (1998)
[Importance of central corneal thickness when studying ocular hypertensive eyes, glaucoma suspects and preperimetric glaucomatous eyes].
E. Alías (2007)
Features of Optic Disc Progression in Patients With Ocular Hypertension and Early Glaucoma
Michael J. Lloyd (2013)
The comparative analysis of optic disc damage in exfoliative glaucoma
G. Tezel (1993)
Image processing for detection of Cataract, Retinopathy of Prematurity and Glaucoma
A. Ektesabi (2015)
Importancia del espesor corneal central en el estudio de hipertensos oculares, sospechosos de glaucoma y glaucomas preperimétricos
E. Alias (2007)
Comparison of Cirrus OCT and Stratus OCT on the ability to detect localized retinal nerve fiber layer defects in preperimetric glaucoma.
Jin Wook Jeoung (2010)
Scanning laser Doppler flowmetry in glaucoma
G. Holló (2004)
Correlation between the progression of optic disc and visual field changes in glaucoma.
S. Miglior (1996)
A Cowey and clinical comparison Retinal nerve fibre layer polarimetry : histological
J. Morgan (1998)
Correlation between central corneal thickness and retinal nerve fiber layer thickness in open-angle glaucoma
Esraa Mohamed (2019)
Trend-based analysis of retinal nerve fiber layer thickness measured by optical coherence tomography in eyes with localized nerve fiber layer defects.
Eun Ji Lee (2011)
Tecniche di imaging e neuropatie ottiche
M. Cesareo (2011)
Discrimination between normal and glaucomatous eyes with visual field and scanning laser polarimetry measurements
R. Lauande-Pimentel (2001)
The role of confocal scanning laser ophthalmoscopy in stereometric differentiation of eye papilla in ocular hypertension, normal tension glaucoma and primary open-angle glaucoma.
R. Gvozdenović (2013)
Correlations between densitometry of red-free photographs and reflectometry with the scanning laser ophthalmoscope in normal subjects and glaucoma patients
R. L. Cooper (2004)
Pathophysiology of human glaucomatous optic nerve damage: insights from rodent models of glaucoma.
J. Morrison (2011)
Visual Function, Optic Nerve Structure, and Ocular Blood Flow Parameters after 1 Year of Glaucoma Treatment with Fixed Combinations
I. Januleviciene (2009)
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