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Morphological Effects Of Chromium And Cobalt Complexes On Bacteria.

A. Theodotou, R. Stretton, A. Norbury, A. Massey
Published 1976 · Chemistry, Medicine

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The biological effects of chromium and cobalt complexes with a variety of bi- and tetradentate ligands on which the donor atoms are all nitrogen were investigated. The other co-ordination positions are occupied by either halogen atoms or water molecules. Graded concentrations of the appropriate complex were inoculated with an overnight culture of Escherichia coli and incubated at 37/sup 0/C for 24 hours. The organisms were then examined microscopically for morphological variations. The minimum inhibitory concentration values of a series of Cr and Co complexes were determined. The cis-complexes were all active.
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