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Synthetic Methyl Hexagalacturonate Hapten Inhibitors Of Anti-homogalacturonan Monoclonal Antibodies LM7, JIM5 And JIM7.
M. Clausen, W. Willats, J. P. Knox
Published 2003 · Chemistry, Medicine
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A range of synthetic methyl hexagalacturonates were used as potential hapten inhibitors in competitive-inhibition enzyme-linked immunosorbent assays (ELISAs) with anti-homogalacturonan monoclonal antibodies LM7, JIM5 and JIM7. The selective inhibition of these antibodies by different haptens provides insight into the structures of the partially methyl-esterified pectin epitopes of these widely used monoclonal antibodies.
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