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Acute Immune Thrombocytopenic Purpura: A Comparative Study Of Very High Oral Doses Of Methylprednisolone And Intravenously Administered Immune Globulin.
D. Albayrak, I. Işlek, A. Kalaycí, N. Gürses
Published 1994 · Medicine
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We compared very high doses of methylprednisolone with intravenously administered immune globulin for treatment of acute idiopathic thrombocytopenic purpura. Fifty-seven children were randomly assigned to receive the immune globulin preparation, 0.5 gm/kg per day for 5 consecutive days (n = 19), orally administered methylprednisolone, 30 mg/kg per day for 7 days (n = 19), or orally administered methylprednisolone, 50 mg/kg per day for 7 days (n = 19). There were no differences in the response of the platelet counts among the groups. We conclude that these two therapies were equally effective; choice between them may be made according to cost and therapy-related risks.
This paper references
Letter: Splenectomy and lymphomas.
R. Stephens (1975)
HIGH-DOSE INTRAVENOUS GAMMAGLOBULIN FOR IDIOPATHIC THROMBOCYTOPENIC PURPURA IN CHILDHOOD
P. Imbach (1981)
Intracranial hemorrhage in children with idiopathic thrombocytopenic purpura.
S. Woerner (1981)
INTRAVENOUS IMMUNOGLOBULIN VERSUS ORAL CORTICOSTEROIDS IN ACUTE IMMUNE THROMBOCYTOPENIC PURPURA IN CHILDHOOD
P. Imbach (1985)
High-dose steroids in childhood acute idiopathic thrombocytopenia purpura.
C. Suarez (1986)
High dose intravenous methylprednisolone or high dose intravenous gammaglobulin for autoimmune thrombocytopenia
A. E. von dem Borne (1988)
Pulse methylprednisolone therapy for acute childhood idiopathic thrombocytopenic purpura.
J. van Hoff (1988)
High dose intravenous methylprednisolone for chronic idiopathic thrombocytopenic purpura.
S. Ozsoylu (1989)
High‐dose intravenous methylprednisolone for acute childhood idiopathic thrombocytopenic purpura
Ş. Özsoylu (1989)
Oral megadose methylprednisolone for childhood acute idiopathic thrombocytopenic purpura.
S. Ozsoylu (1991)
A prospective, randomized trial of high-dose intravenous immune globulin G therapy, oral prednisone therapy, and no therapy in childhood acute immune thrombocytopenic purpura.
V. Blanchette (1993)
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Siraj Mithoowani (2016)
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I. Yıldız (2015)
The Thrombocytopenic Purpuras
S. Gillis (2012)
2011 yılında çocukluk çağı immün trombositopenik purpura hastalığı izlem ve tedavisinde değişiklikler
T. Celkan (2012)
Evidence-Based Emergent Management Of Bleeding Disorders
Katherine Fullerton (2011)
Crimean–Congo haemorrhagic fever: peritoneal and pleural effusion
G. Şensoy (2011)
CLINICAL FEATURES, TREATMENT RESPONSES, AND OUTCOME OF CHILDREN WITH IDIOPATHIC THROMBOCYTOPENIC PURPURA
F. Demircioğlu (2009)
Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura of adults and children: report from an international working group.
F. Rodeghiero (2009)
Possible lower rate of chronic ITP after IVIG for acute childhood ITP an analysis from registry I of the Intercontinental Cooperative ITP Study Group (ICIS)
R. Tamminga (2009)
The Effectiveness of High Dose Dexamethasone for the Initial Treatment of Childhood Acute Idiopathic Thrombocytopenic Purpura
J. S. Choi (2009)
an international working group immune thrombocytopenic purpura of adults and children: report from Standardization of terminology, definitions and outcome criteria in
M. Ruggeri (2009)
Late Side Effects of High-dose Steroid Therapy on Skeletal System in Children With Idiopathic Thrombocytopenic Purpura
Zühal Keskin Yildirim (2008)
Supporting Informed Decisions Polyclonal Intravenous Immunoglobulin in Patients with Immune Thrombocytopenic Purpura : Clinical Systematic
Stella Chen (2008)
Comparison of Megadose Methylprednisolone Versus Conventional Dose Prednisolone in Hematologic Disorders
S. Yetgin (2007)
Acute immune thrombocytopenic purpura in children.
A. Rehman (2007)
About megadose methylprednisolone.
S. Ozsoylu (2007)
Evaluation of clinical characteristics, diagnosis and management in childhood immune thrombocytopenic purpura: a single center's experience.
U. Koçak (2007)
Tratamiento desde el inicio o actitud expectante en el niño con púrpura trombopénica idiopática aguda
E. Monteagudo (2007)
Current options for the treatment of idiopathic thrombocytopenic purpura.
D. Arnold (2007)
A cost‐utility analysis of treatment for acute childhood idiopathic thrombocytopenic purpura (ITP)
Sarah H. O'Brien (2007)
Kikuchi-fujimoto disease associated with extreme leukopenia and thrombocytopenia in an adolescent boy.
M. Eboriadou (2007)
Strategien zur Behandlung von Thrombozytopenien im Kindesalter
W. Ebell (2006)
Recent Advances in the Treatment of Childhood
M. Tarantino (2006)
Recent advances in the treatment of childhood immune thrombocytopenic purpura.
M. Tarantino (2006)
Randomized Trial of Anti-D Immunoglobulin versus Low-Dose Intravenous Immunoglobulin in the Treatment of Childhood Chronic Idiopathic Thrombocytopenic Purpura
Mohsen S El Alfy (2006)
Corticosteroids versus intravenous immune globulin for the treatment of acute immune thrombocytopenic purpura in children: a systematic review and meta-analysis of randomized controlled trials.
C. Beck (2005)
THE EFFECTS OF MEGADOSE METHYLPREDNISOLONE THERAPY ON THE IMMUNE SYSTEM IN CHILDHOOD IMMUNE THROMBOCYTOPENIA
S. Yetgin (2005)
Differential diagnosis and management of thrombocytopenia in childhood.
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