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INCREASED ADIPOSE-TISSUE LIPOPROTEIN-LIPASE ACTIVITY IN MODERATELY OBESE MEN AFTER WEIGHT REDUCTION

R. Schwartz, JohnD. Brunzell
Published 1978 · Medicine

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Most of the many metabolic abnormalities associated with obesity are corrected by weight reduction. Adipose-tissue lipoprotein-lipase activity per cell is increased in obesity. Adipose-tissue lipoprotein-lipase was significantly higher in seven previously obese men studied at a stable reduced weight than in a control population. In fact, enzyme activity was significantly higher than would have been predicted from the obese men's maximum weight. These results indicate that abnormalities in adipose-tissue lipoprotein lipase may have a primary role in the development of obesity.
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