Online citations, reference lists, and bibliographies.
← Back to Search

The Management Of Malignant Pleural Mesothelioma.

G. Maggi, C. Casadio, R. Giobbe, E. Ruffini
Published 2003 · Medicine

Cite This
Download PDF
Analyze on Scholarcy
Share
there was a local recurrence of the tumor 2 years after the last operation on the thorax (right upper lobe of the lung, right pulmonary hilum, and behind the sternum). Surgical resection was not indicated because a right pneumonectomy under permanent left phrenic paralysis would have been necessary for a complete resection. Concurrent chemoradiotherapy using cisplatin (10 mg) 1 5-FU (50 mg) twice a week for 1 month (irradiation 66 Gy totally) was effective and the patient is doing well 1.5 years after treatment and 16 years after the primary operation. I would like to emphasize the importance of long-term follow up of the patient with this tumor. In our case, the first local recurrence was seen 5 years after the primary operation followed by prophylactic adjuvant chemotherapy. In recent reports, Tsuchida et al. [2] described one long-term survivor of this tumor who had a recurrence 6 years after the primary operation and another who had a recurrence 8 years after the primary operation. It would be suggested that this tumor is malignant but slow-moving. Body CT scanning is required for long-term postoperative follow-up to find small tumor recurrences and it would be concluded in the early surgical intervention. In conclusion, because this is a rare tumor, it is very difficult to collect evidence for appropriate treatment in a prospective study. As thoracic oncologists, it is our responsibility to report our experiences with these cases on a global scale.
This paper references



This paper is referenced by
10.1510/icvts.2010.256271
Is pleurectomy and decortication superior to palliative care in the treatment of malignant pleural mesothelioma?
Imran Zahid (2011)
10.1016/j.ejcts.2010.12.024
Clinical and pathological features of three-year survivors of malignant pleural mesothelioma following extrapleural pneumonectomy.
D. Sugarbaker (2011)
10.1200/JCO.2009.26.9944
Soluble mesothelin-related Peptide and osteopontin as markers of response in malignant mesothelioma.
P. Wheatley-Price (2010)
10.1016/S1572-1000(05)00059-1
Photodynamic therapy in the management of malignant pleural mesothelioma: A review.
K. Moghissi (2005)
10.3978/j.issn.2072-1439.2013.04.19
The continual search for ideal biomarkers for mesothelioma: the hurdles.
Fraser Jh Brims (2013)
10.1007/s11748-018-1027-6
Updated meta-analysis of survival after extrapleural pneumonectomy versus pleurectomy/decortication in mesothelioma
D. Magouliotis (2018)
10.1097/JTO.0b013e3181ae26ae
The Mesothelioma and Radical Surgery Randomized Controlled Trial: The MARS Feasibility Study
T. Treasure (2009)
10.1245/s10434-008-9899-9
Surgical Treatment in the Management of Malignant Pleural Mesothelioma: A Single Institution’s Experience
J. Sandick (2008)
10.1097/JTO.0b013e31815608d9
Prognostic Factors in the Treatment of Malignant Pleural Mesothelioma at a Large Tertiary Referral Center
R. Flores (2007)
10.1186/1471-2407-10-54
In vitro and in vivo characterization of highly purified Human Mesothelioma derived cells
A. Melotti (2009)
10.1016/J.RADONC.2006.06.002
The role of radiation therapy in malignant pleural mesothelioma: a systematic review.
Y. Ung (2006)
10.1016/j.ijsu.2008.04.004
Morbidity, mortality, mean survival, and the impact of histology on survival after pleurectomy in 64 patients with malignant pleural mesothelioma.
S. Neragi-Miandoab (2008)
10.1016/j.athoracsur.2008.04.012
Prevalence and pattern of lymph node metastasis in malignant pleural mesothelioma.
A. Abdel Rahman (2008)
10.1007/BF03256303
Biomarkers for Malignant Pleural Mesothelioma
L. Greillier (2012)
10.1245/s10434-011-1728-x
Summary of Prognostic Factors and Patient Selection for Extrapleural Pneumonectomy in the Treatment of Malignant Pleural Mesothelioma
Christopher Cao (2011)
10.1097/JTO.0b013e3181e95cb8
Prognostic Factors for Survival after Surgical Palliation of Malignant Pleural Effusion
J. Pilling (2010)
10.1053/j.semtcvs.2009.07.004
Multimodality strategies in malignant pleural mesothelioma.
W. Weder (2009)
10.1016/J.EJCTS.2007.01.064
Case-control study between extrapleural pneumonectomy and radical pleurectomy/decortication for pathological N2 malignant pleural mesothelioma.
A. Martin-Ucar (2007)
10.1510/ICVTS.2005.123430
The MARS trial: mesothelioma and radical surgery.
T. Treasure (2006)
10.1016/J.EJCTS.2007.09.039
The role of video assisted thoracoscopic pleurectomy/decortication in the therapeutic management of malignant pleural mesothelioma.
A. Nakas (2008)
10.1016/j.acra.2013.10.006
Impact of body habitus on radiologic interpretations.
C. Rajapakse (2014)
10.1016/J.THORSURG.2004.06.008
Preoperative assessment and therapeutic options for patients with malignant pleural mesothelioma.
S. Paul (2004)
10.1097/JTO.0000000000000661
A New Prognostic Score Supporting Treatment Allocation for Multimodality Therapy for Malignant Pleural Mesothelioma: A Review of 12 Years’ Experience
I. Opitz (2015)
10.1016/j.critrevonc.2016.05.004
The Third Italian Consensus Conference for Malignant Pleural Mesothelioma: State of the art and recommendations.
S. Novello (2016)
10.1016/J.RPPNEU.2012.02.004
Mesotelioma deciduóide pleural --- uma entidade rara numa mulher jovem
Cláudia Santos (2012)
10.1016/J.THORSURG.2004.06.007
Pathology of mesothelioma.
J. M. Corson (2004)
10.1007/s00595-015-1275-3
Current surgical strategies for malignant pleural mesothelioma
T. Takuwa (2015)
10.1186/1745-6673-3-34
Gemcitabine combined with oxaliplatin in pretreated patients with malignant pleural mesothelioma: an observational study
A. Xanthopoulos (2008)
10.1016/J.RPPNEN.2012.03.002
Deciduoid pleural mesothelioma--a rare entity in a young woman.
Carlos A. Q. Santos (2012)
10.1016/J.EJCTS.2005.10.008
Multimodality approach in management of malignant pleural mesothelioma.
S. Neragi-Miandoab (2006)
10.1017/9781316402009.004
Multi-modality Imaging of Pleural and Peritoneal Disease
J. Cunningham (2018)
10.1016/j.lungcan.2013.04.024
Systematic review of pleurectomy in the treatment of malignant pleural mesothelioma.
C. Cao (2013)
See more
Semantic Scholar Logo Some data provided by SemanticScholar