Online citations, reference lists, and bibliographies.
← Back to Search

Improvements In The Synthesis Of Terminal Alkynes Via Coupling Of Arylbromides With 2-methylbut-3-yn-2-ol

G. Menchi, A. Scrivanti, U. Matteoli
Published 2000 · Chemistry

Cite This
Download PDF
Analyze on Scholarcy
Share
Abstract The palladium/copper (Pd/Cu)-catalyzed cross-coupling of bromobenzene and 2-methylbut-3-yn-2-ol has been investigated to ascertain the factors influencing the reaction rate. Most usefully, the reaction is carried out using Pd(acetate) 2 as catalyst precursor in combination with PPh 3 and a copper salt. A primary or a cyclic amine is best suited as the reaction solvent. Under these conditions, substrate to palladium ratios of 2000 can be used.
This paper references
10.1246/CL.1992.2177
Generation of Tertiary Phosphine-Coordinated Pd(0) Species from Pd(OAc)2 in the Catalytic Heck Reaction
F. Ozawa (1992)
10.1055/S-1995-5220
Aryl- and Heteroaryl-Alkyne Coupling Reactions Catalyzed by Palladium on Carbon and CuI in an Aqueous Medium
L. Bleicher (1995)
10.1021/OM00039A023
R2PC2H4PR2)Pd(0) Alkene and Ethyne Complexes
J. Krause (1992)
10.1021/JA00167A032
Palladium-catalyzed alkylations in aqueous media
A. Casalnuovo (1990)
10.1016/S0022-328X(00)91277-4
Chemistry of dibenzylideneacetone-palladium(0) complexes: I. Novel tris(dibenzylideneacetone)dipalladium(solvent) complexes and their reactions with quinones
Toshina Ukai (1974)
10.1021/JO00279A040
Rates and regioselectivities of the palladium-catalyzed ethynylation of substituted bromo- and dibromobenzenes
Rina Singh (1989)
10.1016/S1381-1169(98)00396-3
Esters and N,N-dialkylamides of 2-(trifluoromethyl)acrylic acid (TFMAA) through Pd-catalysed carbonylation of fluorinated unsaturated substrates
U. Matteoli (1999)
10.1016/S0022-328X(97)00736-5
Chelating N-heterocyclic carbene ligands in palladium-catalyzed heck-type reactions 1 N-Heterocyclic
W. Herrmann (1998)
10.1016/1381-1169(95)00285-5
Facile catalytic coupling of aryl bromides with terminal alkynes by phospha-palladacycles
W. Herrmann (1996)
10.1021/OM00045A012
Evidence of the formation of zerovalent palladium from Pd(OAc)2 and triphenylphosphine
C. Amatore (1992)
10.1055/S-1992-21465
Palladium-Catalyzed Cross-Coupling Reactions in a Homogeneous Aqueous Medium
J. Genêt (1992)
10.1016/0040-4039(93)85056-3
An Efficient palladium-catalysed reaction of vinyl and aryl halides or triflates with terminal alkynes
M. Alami (1993)
10.1016/S0022-328X(00)94048-8
Synthesis of aryl- and vinyl-substituted acetylene derivatives by the use of nickel and palladium complexes
L. Cassar (1975)
10.1016/S0040-4039(00)91094-3
A convenient synthesis of acetylenes: catalytic substitutions of acetylenic hydrogen with bromoalkenes, iodoarenes and bromopyridines
K. Sonogashira (1975)
10.1016/S0022-328X(00)94049-X
Palladium catalyzed synthesis of aryl, heterocyclic and vinylic acetylene derivatives
H. A. Dieck (1975)
10.1055/S-1981-29448
A Convenient Synthesis of Ethynyl-N-heteroarenes
D. E. Ames (1981)
10.1055/S-1980-29145
A Convenient Synthesis of Ethynylarenes and Diethynylarenes
S. Takahashi (1980)
10.1021/JO00324A015
Facile synthesis of ethynylated benzoic acid derivatives and aromatic compounds via ethynyltrimethylsilane
W. B. Austin (1981)
10.1016/0040-4039(95)01900-3
A CONVENIENT SYNTHESIS OF 2-(6-METHOXY-2-NAPHTHYL)PROPENOIC ACID (A NAPROXEN PRECURSOR)
A. Scrivanti (1995)



This paper is referenced by
Semantic Scholar Logo Some data provided by SemanticScholar