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Research Progress In The Use Of Cationic Carbon Dots For The Integration Of Cancer Diagnosis With Gene Treatment

Lin Yue, Ying-ying Wei, Jiang-bo Fan, Lin Chen, Qiang Li, Jing-lei Du, Shi-ping Yu, Yong-zhen Yang
Published 2021 · Materials Science

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Abstract As a type of carbon dots (CDs) with a positive charge on their surface, cationic carbon dots (CCDs) can be obtained from CDs and amino-containing cationic compounds by one-step or two-step preparation. They not only retain the good fluorescence performance, low toxicity and biocompatibility of CDs, but also improve their gene delivery efficiency and cell uptake capacity. These excellent properties give CCDs potential advantages in the fields of the targeted fluorescence imaging of cancers and gene therapy. This paper reviews the preparation methods and properties of CCDs, suggesting that they can be used as good targeting carriers for imaging cancer and gene therapy. In addition, the basic principles of CCDs for cancer detection and treatment, and their uses in integrated cancer diagnosis and gene therapy are introduced. Current problems and future development trends of CCDs for this purpose are discussed.
This paper references
A powerful nonviral vector for in vivo gene transfer into the adult mammalian brain: polyethylenimine.
B. Abdallah (1996)
Fluorescence intermittency in single cadmium selenide nanocrystals
M. Nirmal (1996)
Improving cancer radiotherapy with 2-deoxy-D-glucose: phase I/II clinical trials on human cerebral gliomas.
B. Mohanti (1996)
The proton sponge: A trick to enter cells the viruses did not exploit[J]
Behr (1997)
Biodistribution of radiolabeled lipid-DNA complexes and DNA in mice.
R. Niven (1998)
Selective reduction of dormant maternal mRNAs in mouse oocytes by RNA interference.
P. Svoboda (2000)
Characteristics and biodistribution of cationic liposomes and their DNA complexes.
H. Ishiwata (2000)
Flat and depressed colonic neoplasms: a prospective study of 1000 colonoscopies in the UK
B. Rembacken (2000)
Electrophoretic analysis and purification of fluorescent single-walled carbon nanotube fragments.
Xiaoyou Xu (2004)
Recent advances in rational gene transfer vector design based on poly(ethylene imine) and its derivatives
M. Neu (2005)
Quantum-sized carbon dots for bright and colorful photoluminescence.
Ya-ping Sun (2006)
Optical Imaging Techniques in Cell Biology
G. Cox (2006)
Fluorescent carbon nanoparticles derived from candle soot.
Haipeng Liu (2007)
Carbon dots for multiphoton bioimaging.
L. Cao (2007)
Surface functionalized carbogenic quantum dots.
A. Bourlinos (2008)
The effect of particle design on cellular internalization pathways
Stephanie E. A. Gratton (2008)
Photoinduced electron transfers with carbon dots.
X. Wang (2009)
Electrochemiluminescence of water-soluble carbon nanocrystals released electrochemically from graphite.
Liyan Zheng (2009)
An aqueous route to multicolor photoluminescent carbon dots using silica spheres as carriers.
Ruili Liu (2009)
Microwave synthesis of fluorescent carbon nanoparticles with electrochemiluminescence properties.
Hui Zhu (2009)
Organocatalytic asymmetric aza-Nazarov cyclization of an azirine.
N. Shimada (2010)
Study on the fluorescence characteristics of carbon dots.
X. Mao (2010)
Endocytosis of nanomedicines.
G. Sahay (2010)
P53 in human melanoma fails to regulate target genes associated with apoptosis and the cell cycle and may contribute to proliferation
K. Avery-Kiejda (2010)
Molecular mechanisms underlying Ca2+-mediated motility of human pancreatic duct cells.
H. Dong (2010)
Molecular mechanism and physiological functions of clathrin-mediated endocytosis
H. McMahon (2011)
Polyamine-functionalized carbon quantum dots for chemical sensing
Yongqiang Dong (2012)
Polyethyleneimine modified fluorescent carbon dots and their application in cell labeling.
B. Han (2012)
Nano-carrier for gene delivery and bioimaging based on carbon dots with PEI-passivation enhanced fluorescence.
Chang-jun Liu (2012)
Optical Imaging Techniques in Cell Biology, by Guy Cox. CRC Press, Taylor & Francis Group, Boca Raton, FL, 2012, 268 pages. ISBN 0-8493-3919-7 (Hardcover)
A. Periasamy (2013)
Missed diagnosis of early gastric cancer or high-grade intraepithelial neoplasia.
Wei Ren (2013)
Pollutant soot of diesel engine exhaust transformed to carbon dots for multicoloured imaging of E. coli and sensing cholesterol
K. M. Tripathi (2014)
A cationic cholesterol based nanocarrier for the delivery of p53-EGFP-C3 plasmid to cancer cells.
S. Misra (2014)
Fluorescent carbon dots as an efficient siRNA nanocarrier for its interference therapy in gastric cancer cells
Qing Wang (2014)
Carbon-dot-based two-photon visible nanocarriers for safe and highly efficient delivery of siRNA and DNA.
Liqin Wang (2014)
Synthesis of polyethyleneimine capped carbon dots for preconcentration and slurry sampling analysis of trace chromium in environmental water samples.
Yueling Liu (2015)
Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012
J. Ferlay (2015)
The present situation and new progress of imaging examination of breast cancer[J]
Nie (2015)
Synthesis of nitrogen-doping carbon dots with different photoluminescence properties by controlling the surface states.
Y. Yuan (2016)
Multi-functionalized carbon dots as theranostic nanoagent for gene delivery in lung cancer therapy
Yu-Fen Wu (2016)
Cationic carbon quantum dots derived from alginate for gene delivery: One-step synthesis and cellular uptake.
Jie Zhou (2016)
Cisplatin and paclitaxel co-delivered by folate-decorated lipid carriers for the treatment of head and neck cancer
Jiying Yang (2016)
Morpholine Derivative-Functionalized Carbon Dots-Based Fluorescent Probe for Highly Selective Lysosomal Imaging in Living Cells.
Luling Wu (2017)
Synthesis of multicolor photoluminescent carbon quantum dots functionalized with hydrocarbons of different chain lengths
Kayo O. Vieira (2017)
Red, Yellow, and Blue Luminescence by Graphene Quantum Dots: Syntheses, Mechanism, and Cellular Imaging.
Tianfeng Gao (2017)
Biomarkers of folate and vitamin B12 and breast cancer risk: report from the EPIC cohort
M. Matejcic (2017)
An active structure preservation method for developing functional graphitic carbon dots as an effective antibacterial agent and a sensitive pH and Al(iii) nanosensor.
Peng Hou (2017)
One-step synthesis of photoluminescent carbon dots with excitation-independent emission for selective bioimaging and gene delivery.
X. Yang (2017)
One-Pot Hydrothermal Synthesis of Carbon Dots with Efficient Up- and Down-Converted Photoluminescence for the Sensitive Detection of Morin in a Dual-Readout Assay.
Jiayu Li (2017)
Super-Cationic Carbon Quantum Dots Synthesized from Spermidine as an Eye Drop Formulation for Topical Treatment of Bacterial Keratitis.
Hong-Jyuan Jian (2017)
The use of carbon quantum dots as fluorescent materials in white LEDs
Bo Cui (2017)
Carbon quantum dots with intrinsic mitochondrial targeting ability for mitochondria-based theranostics.
Xian-Wu Hua (2017)
Amphiphilic carbon dots as versatile vectors for nucleic acid and drug delivery.
Hai-jiao Wang (2017)
Chitosan-Based Composite Materials for Prospective Hemostatic Applications
Zhang Hu (2018)
Progress in research on the preparation of carbon dots and their use in tumor theranostics
Chunhe Lu (2018)
The cytotoxicity of water-soluble carbon nanotubes on human embryonic kidney and liver cancer cells
Shiping Yu (2018)
Rapid and green synthesis of fluorescent carbon dots from starch for white light-emitting diodes
Jingxia Zheng (2018)
Photoluminescent Cationic Carbon Dots as efficient Non-Viral Delivery of Plasmid SOX9 and Chondrogenesis of Fibroblasts
X. Cao (2018)
Author Correction: Cathelicidin-OA1, a novel antioxidant peptide identified from an amphibian, accelerates skin wound healing
Xiaoqing Cao (2018)
Mechanism, Tuning and Application of Excitation-Dependent Fluorescence Property in Carbon Dots
Junli Wang (2018)
Cui (2018)
Mechanism, tuning and application of excitation-dependent fluorescence property in carbon dots[J]
Wang (2018)
Preparation of nitrogen-doped carbon dots with a high fluorescence quantum yield for the highly sensitive detection of Cu2+ ions, drawing anti-counterfeit patterns and imaging live cells
Wen Liu (2019)
Photoluminescent functionalized carbon dots for CRISPR delivery: synthesis, optimization and cellular investigation.
A. Hasanzadeh (2019)
Microwave-assisted and one-step synthesis of PEG passivated fluorescent carbon dots from gelatin as an efficient nanocarrier for methotrexate delivery
N. Arsalani (2019)
Green fluorescent carbon quantum dots functionalized with polyethyleneimine, and their application to aptamer-based determination of thrombin and ATP
Ying Guo (2019)
Dual-ligand functionalized carbon nanodots as green fluorescent nanosensors for cellular dual receptor-mediated targeted imaging.
Fangfang Du (2019)
Fluorometric label-free aptasensor for detection of the pesticide acetamiprid by using cationic carbon dots prepared with cetrimonium bromide
Z. Saberi (2019)
AS1411 aptamer modified carbon dots via polyethylenimine‐assisted strategy for efficient targeted cancer cell imaging
T. Kong (2019)
Interpretation of the 2018 global cancer statistics report[J]
Wang (2019)
Assembling Defined DNA Nanostructure with Nitrogen-Enriched Carbon Dots for Theranostic Cancer Applications.
Di Wu (2020)
Carbon dots derived from flax straw for highly sensitive and selective detections of cobalt, chromium, and ascorbic acid.
Guangkuo Hu (2020)
Research progress on the use of micro/nano carbon materials for antibacterial dressings
Y. Liu (2020)
Synthesis and Applications of Chiral Carbon Quantum Dots
W. Yingying (2020)
Synthesis of Multi-Color Fluorescent Carbon Dots From Mint Leaves: A Robust Bioimaging Agent with Potential Antioxidant Activity.
Sadia Shahid (2020)
Dual Targeted Therapy in HER2-positive Breast Cancer Cells with the Combination of Carbon Dots/HER3 siRNA and Trastuzumab.
Mengjun Shu (2020)
Synthesis and applications of chiral carbon quantum dots[J]
Wei (2020)

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