Online citations, reference lists, and bibliographies.
← Back to Search

Recent Advances In Various Emerging Vescicular Systems: An Overview

M. Gangwar, Ragini Singh, Goel Rk, G. Nath
Published 2012 · Medicine

Cite This
Download PDF
Analyze on Scholarcy
Share
Abstract Liposomes have been widely investigated since 1970 as drug carriers for improving the delivery of therapeutic agents to specific sites in the body. As a result, numerous improvements have been made to make this technology potential the treatment of certain diseases in the clinics. This review mainly focused on various aspects related to the vesicular system, including method of preparation, stabilization, drawbacks, and applications. Various types of vesicular systems such as liposomes, niosomes, transfersomes, pharmacosomes, and nanoparticle have been discussed briefly along with some other emerging vescicular systems (photosomes, archaesomes, genosomes, cryptosomes, discomes) focusing on cell specific gene transfer, photodynamic therapy and ligand mediated drug targeting. Present applications of the liposomes are in the immunology, dermatology, vaccine adjuvant, eye disorders, brain targeting, infective disease and in tumour therapy. The new developments in this field are of specific binding properties of a drug-carrying liposome to a target cell such as a tumor cell and specific molecules in the body (antibodies, proteins, peptides etc), stealth liposomes which are especially used as carriers for hydrophilic (water soluble) anticancer drugs like doxorubicin, mitoxantrone and bisphosphonate-liposome mediated depletion of macrophages. This review would help researchers working in the area of liposomal drug delivery.
This paper references
10.1016/j.ijpharm.2009.01.023
Targeted delivery of doxorubicin using stealth liposomes modified with transferrin.
X. Li (2009)
10.1111/j.1468-2494.2008.00416.x
Novel cosmetic delivery systems: an application update
V. Patravale (2008)
10.2174/1567201054368020
Transdermal delivery of an analgesic agent using elastic liposomes: preparation, characterization and performance evaluation.
S. Jain (2005)
Liposomal drug delivery systems--clinical applications.
Parveen Goyal (2005)
10.1016/j.jconrel.2010.10.019
All-trans retinoic acid stealth liposomes prevent the relapse of breast cancer arising from the cancer stem cells.
Ruo-Jing Li (2011)
10.2745/DDS.19.530
Liposomal formulation technology: in the case of preparation of liposomes for gene delivery
Hiroshi Kikuchi (2004)
Delivery of nonsteroidal anti-inflammatory agents like diclofenac
S Jain (2005)
10.1016/j.bbrc.2010.03.041
Investigation of archaeosomes as carriers for oral delivery of peptides.
Z. Li (2010)
Stealth liposomes: an improved sustained release system for 1-beta-D-arabinofuranosylcytosine.
T. Allen (1992)
10.1016/S0169-409X(97)00108-7
Recent advances in liposome technologies and their applications for systemic gene delivery.
Cullis (1998)
10.1016/j.jconrel.2009.03.019
Aerosolized liposomes with dipalmitoyl phosphatidylcholine enhance pulmonary insulin delivery.
S. Chono (2009)
10.1016/j.phrs.2010.03.005
Targeting nanoparticles to cancer.
M. Wang (2010)
10.1016/j.jconrel.2011.07.028
Circulation kinetics and biodistribution of dual-labeled polymersomes with modulated surface charge in tumor-bearing mice: comparison with stealth liposomes.
J. Lee (2011)
Sphingosomes a novel approach to vesicular drug delivery
S. Saraf (2011)
10.1155/2010/652048
Silica-coated liposomes for insulin delivery
Neelam Dwivedi (2010)
10.1016/S0169-409X(00)00069-7
Virosomes: evolution of the liposome as a targeted drug delivery system.
Y. Kaneda (2000)
10.1111/j.1751-1097.2008.00530.x
Light‐sensitive Intelligent Drug Delivery Systems †
C. Alvarez-Lorenzo (2009)
10.4103/0378-6323.62961
Topical treatment in vitiligo and the potential uses of new drug delivery systems.
B. Garg (2010)
10.4268/CJCMM20110709
[Effect of phospholipid composition on pharmaceutical properties and anti-tumor activity of stealth liposomes containing brucine].
M. Chen (2011)
10.1016/j.vaccine.2008.02.026
Archaeosome adjuvants: immunological capabilities and mechanism(s) of action.
L. Krishnan (2008)
10.1039/b920900j
DNA-METAFECTENE PRO complexation: a physical chemistry study.
Manuel Alatorre-Meda (2010)
10.2174/138161211798194549
Prodrugs in photodynamic anticancer therapy.
R. Musiol (2011)
10.3109/08982100903402962
Archaeosomes as carriers for topical delivery of betamethasone dipropionate: in vitro skin permeation study
Ana González‐Paredes (2010)
10.6030/1939-067X-4.1.16
Targeting ischemic penumbra Part II: selective drug delivery using liposome technologies.
S. Liu (2011)
10.3109/08982109209010224
Stealth Liposomes, Ninja Liposomes, Or Cryptosomes: Are They Really Sterically Stabilized Liposomes?
L. Huang (1992)
Circulation time of cryptosomes
G Blume (1993)
[Enhanced absorption of breviscapine photosomes in small intestine of rats].
X. Tang (2005)
TRANSFEROSOMES: AN EMERGING TOOL FOR TRANSDERMAL DRUG DELIVERY
P. R. Kulkarni (2011)
10.1039/c0pp00147c
Targeted photodynamic therapy--a promising strategy of tumor treatment.
A. Bugaj (2011)
10.1002/ps.3606
Delivery
T. H. Miller (2013)
10.2147/IJN.S19917
Liposomes containing glycocholate as potential oral insulin delivery systems: preparation, in vitro characterization, and improved protection against enzymatic degradation
M. Niu (2011)
Proniosomes as drug Mayank Gangwar et al ./Asian Pacific Journal of Tropical Biomedicine (2012)S1176-S1188 S1187 carriers
V Sankar (2010)
10.1016/j.jconrel.2010.11.002
Antibody derivatization and conjugation strategies: application in preparation of stealth immunoliposome to target chemotherapeutics to tumor.
A. S. Manjappa (2011)
10.2174/156720111795256138
M cells prefer archaeosomes: an in vitro/in vivo snapshot upon oral gavage in rats.
M. Morilla (2011)
10.1021/jp7095828
Compaction process of calf thymus DNA by mixed cationic-zwitterionic liposomes: a physicochemical study.
A. Rodríguez-Pulido (2008)
10.18433/J3P88Z
Effects of stealth liposomal daunorubicin plus tamoxifen on the breast cancer and cancer stem cells.
J. Guo (2010)
10.1016/j.jconrel.2009.12.002
Temperature-sensitive liposomes for doxorubicin delivery under MRI guidance.
M. de Smet (2010)
10.2174/187221109789105630
New generation of liposomes called archaeosomes based on natural or synthetic archaeal lipids as innovative formulations for drug delivery.
T. Benvegnu (2009)
TRANSFERSOMES: A SURROGATED CARRIER FOR TRANSDERMAL DRUG DELIVERY SYSTEM
J. R. Walve (2011)
Niosomes : The ultimate drug carrier
Dubey Subodh (2010)
10.1016/j.vaccine.2011.05.015
Archaeosomes with encapsulated antigens for oral vaccine delivery.
Z. Li (2011)
The effect of stealth liposomes on pharmacokinetics, tissue distribution and anti-tumor activity of oridonin.
Chuanjin Wang (2009)
10.1684/BDC.2011.1389
Thérapie photodynamique et carcinomes urothéliaux
P. Colin (2011)
10.1684/bdc.2011.1389
[Photodynamic therapy and urothelial carcinoma].
P. Colin (2011)
10.1155/2011/396068
Preparation and Characterization of Stealth Archaeosomes Based on a Synthetic PEGylated Archaeal Tetraether Lipid
Julie Barbeau (2011)
Pharmacosomes: an emerging vesicular system
D Kavitha (2010)
10.1155/2010/354364
The effects of coupling agents on the properties of polyimide/nano-Al 2 O 3 three-layer hybrid films
Lizhu Liu (2010)
10.3322/caac.20114
Photodynamic therapy of cancer: An update
P. Agostinis (2011)
10.3109/1061186X.2011.595490
Chlorotoxin-modified stealth liposomes encapsulating levodopa for the targeting delivery against the Parkinson’s disease in the MPTP-induced mice model
Yu Xiang (2012)
10.1586/erv.10.34
Archaeal lipid mucosal vaccine adjuvant and delivery system
G. B. Patel (2010)
10.1016/0005-2736(93)90351-Y
Molecular mechanism of the lipid vesicle longevity in vivo.
G. Blume (1993)
Photodynamic therapy for photorejuvenation and non-oncologic indications: overview and update.
E. Kohl (2011)
10.1080/17482940902724044
Physicochemical characterization of stealth liposomes encapsulating an organophosphate hydrolyzing enzyme
M. Budai (2009)
10.3109/08982109209010210
Stealth Liposomes: Five Years On
T. Allen (1992)
10.1016/j.ijpharm.2011.09.042
Delivery systems for natural antioxidant compounds: Archaeosomes and archaeosomal hydrogels characterization and release study.
A. González-Paredes (2011)
10.1016/j.biomaterials.2010.05.045
Highly temperature-sensitive liposomes based on a thermosensitive block copolymer for tumor-specific chemotherapy.
K. Kono (2010)
Proniosomes as drug carriers.
V. Sankar (2010)
The ultimate drug carrier
S Dubey (2010)
10.2217/nnm.11.144
Photodynamic therapy with fullerenes in vivo: reality or a dream?
S. K. Sharma (2011)
10.1016/j.athoracsur.2011.02.062
Photodynamic therapy and the evolution of a lung-sparing surgical treatment for mesothelioma.
J. Friedberg (2011)



This paper is referenced by
SPHINGOSOME: A NOVEL VESICULAR DRUG DELIVERY SYSYTEM
Abhijeet Sunder Kunwarpuriya (2015)
PHARMACOSOMES: A NOVEL CARRIER FOR TARGETED AND CONTROLLED VESICULAR DRUG DELIVERY SYSTEM
Vijay Kumar Singh (2014)
10.1016/j.tips.2013.10.002
Potential therapeutic applications of biosurfactants.
E. Gudiña (2013)
A Review on Pharmacosomes.
Sonam Ranga (2014)
10.5772/58459
Liposomes as Potential Drug Carrier Systems for Drug Delivery
Melis Çağdaş (2014)
10.4018/978-1-5225-0751-2.CH005
Vesicular Drug Delivery Systems: A Special Emphasis on Pharmacosomes
P. Khulbe (2017)
10.1016/j.jcis.2015.01.022
Microbial surfactants: fundamentals and applicability in the formulation of nano-sized drug delivery vectors.
L. Rodrigues (2015)
VESICULAR DRUG DELIVERY SYSTEM: A NOVEL APPROACH
K. C. Ashara (2014)
10.1155/2014/978351
Application of Liposomes in Treatment of Rheumatoid Arthritis: Quo Vadis
B. Kapoor (2014)
10.1007/978-981-15-1664-1
Nanomedicine for Bioactives: Healthcare applications
Farhan J Ahmad (2020)
Optimization of formulation and process condition for downsizing of labisia pumila and ficus deltoidea loaded niosome
S. Chen (2015)
10.1016/j.cis.2018.01.003
Prodrugs, phospholipids and vesicular delivery - An effective triumvirate of pharmacosomes.
B. Kapoor (2018)
10.7324/JAPS.2015.50215
Design, development and characterization of serratiopeptidase loaded albumin nanoparticles -
H. Kaur (2015)
10.1016/j.colsurfb.2020.111262
Lipid vesicles: A versatile drug delivery platform for dermal and transdermal applications.
I. A. Chacko (2020)
10.1208/s12249-018-1252-4
Drug-Phospholipid Complex—a Go Through Strategy for Enhanced Oral Bioavailability
Kaushik Kuche (2019)
SPHINGOSOMES: APPLICATIONS IN TARGETED DRUG DELIVERY
Srinivas Lankalapalli (2012)
10.24018/10.24018/IIJMPS.2018.V1I1.22
A REVIEW ON TRANSFEROSOMES AS ULTRA DEFORMABLE VESICULAR CARRIERS FOR TRANSDERMAL DRUG DELIVERY
Ravalika Veldurthi (2017)
10.1016/j.ijbiomac.2014.01.019
The novel polymeric systems for photodynamic therapy technique.
M. Saboktakin (2014)
10.1016/B978-0-323-52729-3.00003-2
Chapter 3 – Liposomes
M. Shah (2017)
10.2147/DDDT.S232325
Potential Use of Microbial Surfactant in Microemulsion Drug Delivery System: A Systematic Review
M. Ohadi (2020)
10.1016/j.ijpharm.2020.119178
Dimeric artesunate phospholipid-conjugated liposomes as promising anti-inflammatory therapy for rheumatoid arthritis.
Yiwei Zhang (2020)
SPHINGOSOMES: A NOVEL VESICULAR DRUG DELIVERY SYSTEM
Prasanna Kumar Desu (2013)
10.5897/AJPPX2013.0004
Lipid-based drug delivery systems (LDDS): Recent advances and applications of lipids in drug delivery
S. Chime (2013)
10.1208/s12249-016-0661-5
Ultradeformable Liposomes: a Novel Vesicular Carrier For Enhanced Transdermal Delivery of Procyanidins: Effect of Surfactants on the Formation, Stability, and Transdermal Delivery
Rencai Chen (2016)
Transdermal Drug Delivery Through Carriers: Transfersomes
N. Kaur (2014)
10.4172/JAA.1000083
Virosomes-Hybrid Drug Delivery Systems
Mustafeez Mujtaba Babar (2013)
FORMULATION AND CHARACTERIZATION OF ZIDOVUDINE PRONIOSOMAL GEL
Bushra Ahmedi (2016)
10.1007/978-981-15-1664-1_11
New Paradigms in the Treatment of Skin Infections: Lipid Nanocarriers to the Rescue
Karan Razdan (2020)
PRONIOSOMAL GEL FOR IMPROVED TRANSDERMAL DRUG DELIVERY: AN OVERVIEW
Prashant G. Pandit (2015)
10.22270/JDDT.V9I1-S.2234
An updated review on pharmacosomes, a vesicular drug delivery system
B. Supraja (2019)
DDDT_A_232325 541..550
M. Ohadi (2020)
10.1016/j.jphotobiol.2013.07.014
Quercetin deformable liposome: preparation and efficacy against ultraviolet B induced skin damages in vitro and in vivo.
D. Liu (2013)
See more
Semantic Scholar Logo Some data provided by SemanticScholar